Due to the COVID-19 crisis, the information below is subject to change,
in particular that concerning the teaching mode (presential, distance or in a comodal or hybrid format).
5 credits
30.0 h + 30.0 h
Q2
Teacher(s)
Page Melissa; Soumillion Patrice;
Language
English
Prerequisites
The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Main themes
Main themes to cover :
Introduction to metabolism
Bioenergetics
Biochemical transport phenomenon
Main metabolic ways :
Glycolysis and hexose catabolism
Metabolism of glycogen and glyconeogenesis
Oxidation of fatty acids and biosynthesis of lipids
Krebs cycle
Electron transport, oxidative phosphorylation
Metabolism of amino acids, nucleotides and linked molecules.
Main ways of regulation.
The exercises are divided into two complementary parts :
One, followed in the case of CHIM BAC, consists of practical work on a specific question in biochemistry.
The other, for all, consists of preparing, presenting and discussing, in groups, a question linked to a biochemical problem, but voluntarily carrying onto other disciplines of life sciences.
Aims
At the end of this learning unit, the student is able to : | |
| 1 | The objective of the theoretical course is to examine the general aspects of glucides, lipids, amino acids and nucleotides metabolism, as well as their regulation. The course must allow the acquisition and mastering of several types of competences: General knowledge of metabolism and its regulation modes ; comprehension of reactional mechanisms, representation of main metabolic ways, as well as their main regulations ; Integration of metabolism in the physiology context of cells and organisms, mainly animal. The goal of exercises is : Deepening, by practical exercises, basic notions seen in the theoretical course ; by the realization of a personal interdisciplinary work, based on a problem-situation, integrating the understanding of metabolic biochemistry in the context of life sciences. |
Content
Bioenergetic principles; carbohydrate metabolism (glycolysis, fermentation, phosphogluconate pathway, gluconeogenesis and glycogenogenesis); Krebs cycle and glyoxylate; respiratory chain and oxidative phosphorylation; photosynthesis; oxidation and biosynthesis of lipids; urea cycle; synthesis and degradation of amino acids and other important nitrogen compounds; nucleotide metabolism.
Instruction will take place in english.
Instruction will take place in english.
Teaching methods
Due to the COVID-19 crisis, the information in this section is particularly likely to change.
The skills targeted by the course will be developed using lectures. Students will give a presentation on a topic to choose from a list of topics proposed by teachers. Laboratory sessions for chemistry students are not part of Part A for students in biology and veterinary science.
Evaluation methods
Due to the COVID-19 crisis, the information in this section is particularly likely to change.
Written exam including questions requiring precise / short answers, theoretical developments or problem solving. The student presentations are also part of the overall assessment as well as the laboratory sessions (except part A).
Online resources
Slideshows are available via the moodle platform
Bibliography
- Lehninger Principles of biochemistry 7th edition
- Voet & Voet Biochemistry 4th Edition
Teaching materials
- Lehninger Principles of biochemistry 7th edition
- Voet & Voet Biochemistry 4th Edition
Faculty or entity
CHIM
