Molecular Virology

wsbim1302  2020-2021  Bruxelles Woluwe

Molecular Virology
Due to the COVID-19 crisis, the information below is subject to change, in particular that concerning the teaching mode (presential, distance or in a comodal or hybrid format).
3 credits
25.0 h

The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Main themes
General structure, replication cycles, and classification of viruses; antiviral agents and vaccination; Reverse genetics and use of viruses as vectors. Selected viruses will be taken as exemples to illustrate the diversity of host-virus interactions and the outcome thereof (latency, cellular transformation, oncogenesis, antigenic variation and escape of immune responses, AIDS...).

At the end of this learning unit, the student is able to :

1 The lectures present basic concepts on structure and function of animal viruses. It outlines the relationship between the basic replication cycle of the virus and the outcome of the infection for the host. It aims at giving the student the ability to use basic knowledge of viral life cycles as a tool to understand the techniques that are used to detect viruses, develop antiviral compounds.
Historics of viruses discovery, characterization and classification. Structure and replication cycle of animal viruses (DNA viruses, RNA viruses and retroviruses). Host-virus interaction (cellular transformation, latency, antigenic variation, cancer, oncogenes, AIDS). Vaccination and antiviral agents. Reverse genetics and use of viruses. Non-conventional agents.
Teaching methods

Due to the COVID-19 crisis, the information in this section is particularly likely to change.

classes and discussions
Evaluation methods

Due to the COVID-19 crisis, the information in this section is particularly likely to change.

written examination
Other information
Prerequisite: basic biochemistry, molecular and cellular biology: nature and function of nucleic acids and proteins; gene expression, protein synthesis, modification and targeting in eucaryotic cells; organization and function of the eucaryotic cell. Assessment: By written (or oral) exam. The students will be examined on their knowledge of the subject, and on their capacity to use this knowledge to solve problems
Online resources
web site of "initiation to Virology"  (in french):
files with the illustration slides posted on Moodle
Faculty or entity

Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Bachelor in Biomedicine