Cellular and molecular pathophysiology of human diseases (Part 1)

wsbim2184  2021-2022  Bruxelles Woluwe

Cellular and molecular pathophysiology of human diseases (Part 1)
3 credits
30.0 h
Q1
Language
English
Prerequisites
This course requires good knowledge of cellular and molecular biology, biochemistry of cell metabolism, immunology, cell and organ physiology, and human pathology.
Main themes
At the end of the year, the student will :
  • know the pathophysiology of the diseases covered during classes, from the molecule to the cell, the cell to the organ, and the organ to the organism
  • understand/be able to explain the link between the molecular and cellular alterations described and the development of the chronic diseases covered during classes, as well as the mode of action of drugs targeting these alterations and their impact in other organs
  • be able to analyze and criticize a conference or paper in that field ; use his/her new knowledge and skills to investigate unaswered questions on the topic
  • imagine new approaches to study the pathophysiology of other diseases
Aims

At the end of this learning unit, the student is able to :

1 At the end of the class, the student should:
(1) know the pathophysiology of diseases specifically addressed during the class, not only from the molecular and cellular point of view, but also in a larger perspective (organs, organism);
(2) understand and explain the link between the molecular and cellular dysfunction and disease development; understand and explain the mode of action of drugs targeting these alterations;
(3) be able to critically analyze a presentation or scientific paper about
the subject ; use her knowledge to address new questions in the field ;
(4) be able to propose experimental approaches to study the molecular and cellular pathophysiology of other diseases.
 
Content
The classes will cover the pathophysiological mechanisms underlying the development of frequent non-communicable human diseases, the drugs targeting these mechanisms and unanswered questions on the topic (biomedical research). The link between the molecular, cellular, and tissue alterations and their impact on the whole organism will be highlighted as much as possible. Diseases covered during classes: diabetes and its complications ; cardiovascular diseases; respiratory diseases; neurodegenerative diseases ; cancers.
Teaching methods
The course consists in a series of lectures or inverted classes on specific topics.
Evaluation methods
Written examination, unless specified otherwise by each professor.
Questions are written in English, but students can anwer in French or English.
The final note will be the geometric mean of the notes obtained in each part. This means that, in case of a major failure in one part, the final note will be lower than the arithmetic mean of the notes obtained in each part.
Other information
This course requires good knowledge of cellular and molecular biology, biochemistry of cell metabolism, immunology, cell and organ physiology, and human pathology.
Online resources
Slides projected during classes and additional documents will be posted on MoodleUCL.
Teaching materials
  • aucun support obligatoire (documents et slides sur Moodle)
Faculty or entity


Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Sigle
Credits
Prerequisites
Aims
Master [60] in Biomedicine

Master [120] in Biomedicine