Teacher(s)
Language
French
Prerequisites
It is recommended that the student master the basic notions of organic and general chemistry, as developed in first-year courses in the faculty of science or faculty of bioengineering.
Main themes
Introduction to basic molecules of biochemistry
1. Amino acids and proteins
2. Carbohydrates
3. Lipids and biological membranes
4. Nucleic acids
Function of bio molecules
1. Structure of proteins
2. Enzymes
Notions of molecular biochemistry
1. Replication of DNA
2. Transcription of DNA into RNA
3. Nucleic acid-protein complexes
4. Biosynthesis of proteins
The practical work illusrates the properties of the main classes of biomolecules studied in the theoretical course and initiatee students to a certain number of techniques used currently in biochemistry.
1. Amino acids and proteins
2. Carbohydrates
3. Lipids and biological membranes
4. Nucleic acids
Function of bio molecules
1. Structure of proteins
2. Enzymes
Notions of molecular biochemistry
1. Replication of DNA
2. Transcription of DNA into RNA
3. Nucleic acid-protein complexes
4. Biosynthesis of proteins
The practical work illusrates the properties of the main classes of biomolecules studied in the theoretical course and initiatee students to a certain number of techniques used currently in biochemistry.
Content
This first biochemistry course will aim at presenting the structure and chemical properties of the main molecular protagonists of the living world.
The different chapters will be devoted to the detailed description of the major classes of biomolecules (amino acids, nucleotides, lipids, carbohydrates, proteins, enzymes).
The way in which small molecules are assembled into larger structures (polymers) will also be discussed.
The chemical origin of the main types of covalent and non-covalent interactions between biomolecules will allow a good understanding of the modes of biosynthesis and molecular recognition which are at the heart of the organization and functioning of living organisms.
The behavior of enzymes, the main workers of life, will also be introduced, by describing the catalytic properties and the modes of regulation of these properties.
The course will also provide a first descriptive introduction to the three major processes that are at the heart of the functioning of any living cell, namely replication, transcription and translation.
This introduction will then serve as a basis for presenting the basics of modern molecular biology and recombinant DNA technologies that allow us to manipulate DNA in a surgical manner today.
Five half-day practical sessions are also organized to familiarize the student with the experimental manipulation of the main classes of biomolecules (sugars, lipids, proteins, enzymes).
The different chapters will be devoted to the detailed description of the major classes of biomolecules (amino acids, nucleotides, lipids, carbohydrates, proteins, enzymes).
The way in which small molecules are assembled into larger structures (polymers) will also be discussed.
The chemical origin of the main types of covalent and non-covalent interactions between biomolecules will allow a good understanding of the modes of biosynthesis and molecular recognition which are at the heart of the organization and functioning of living organisms.
The behavior of enzymes, the main workers of life, will also be introduced, by describing the catalytic properties and the modes of regulation of these properties.
The course will also provide a first descriptive introduction to the three major processes that are at the heart of the functioning of any living cell, namely replication, transcription and translation.
This introduction will then serve as a basis for presenting the basics of modern molecular biology and recombinant DNA technologies that allow us to manipulate DNA in a surgical manner today.
Five half-day practical sessions are also organized to familiarize the student with the experimental manipulation of the main classes of biomolecules (sugars, lipids, proteins, enzymes).
Teaching methods
Lectures and practical work in the classroom
Evaluation methods
Written exam in session (80% of the final grade), quiz and practical work reports (20% of the final grade).
Bibliography
- Principles of Biochemistry de Lehninger
- Biochemistry de Voet et Voet
Faculty or entity
