Projects

  • To study the role of miRNA (eg, miR199a) on endothelial function in various diseases including hypertension and endocrine disorders

  • To investigate the beneficial role of prebiotics and aggravating impact of PUFA depletion on endothelial dysfunction, an early key marker of cardiovascular diseases.

  • To dissect the protective effects of hypoxic preconditioning on the vascular function, with a specific focus on  the role of transient receptor potential cation channels V4 (TRPV4) and gap junctions.

  • To study mediators of the endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation, in particular those located in caveolae and/or regulated by the structural protein caveolin-1.