In brief

Bruxelles Woluwe

The objective of our research is to use delivery systems and biomaterials as a mean to improve therapeutic outcomes of drugs. We develop drug delivery systems going from nano-scale, through micro-scale up to macro-scale (Figure 1A).

Our different research applications can be gathered into two research themes (Figure 1B):

  1. Nanomedicines
    a. Cancer: this theme focuses on targeted theranostic nanoparticles loaded with anticancer drugs, siRNA, adjuvanted recombinant antigens and gene vaccines.
    b. Mucosal delivery routes: this theme includes the research on oral delivery using nanomedicines, cutaneous delivery and pulmonary delivery.
    c. CNS diseases: the objective is to develop nanomedicines that would stimulate CNS repair by local, systemic, or mucosal delivery
  2. Regenerative medicine:
    This theme focuses on tissue regeneration and restoration and gathers the research on spinal cord regeneration, dental restoration and skin wound healing.

Figure 1:  A. Drug delivery systems and biomaterials developed/used by the ADDB group; B. Biomedical applications