All publications

Bruxelles Woluwe


  1. Guichard, Marie-Julie ; Wilms, Tobias ; Mahri, Sohaib ; Patil, Harshad P. ; Hoton, Delphine ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Cheou, Paméla ; Beka, Mathilde ; Marbaix, Etienne ; Leal, Teresinha ; Vanbever, Rita.
    PEGylation of recombinant human deoxyribonuclease I provides a long‐acting version of the mucolytic for patients with cystic fibrosis.
    In: Advanced Therapeutics, Vol. 4, no. 2, p. 2000146 (2020). doi:10.1002/adtp.202000146.
  2. Lopes, Alessandra ; Bastiancich, Chiara ; Bausart, Mathilde ; Ligot, Sophie ; Lambricht, Laure ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Gallez, Bernard ; Préat, Véronique ; Vandermeulen, Gaëlle.
    New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models.
    In: Journal for immunotherapy of cancer, Vol. 9, no.4, p. e001243 (2021). doi:10.1136/jitc-2020-001243.
  3. Mahri, Sohaib ; Hardy, Eléonore ; Wilms, Tobias ; De Keersmaecker, Herlinde ; Braeckmans, Kevin ; De Smedt, Stefaan ; Bosquillon, Cynthia ; Vanbever, Rita.
    PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages.
    In: International journal of pharmaceutics, Vol. 593, p. 120107 (2021). doi:10.1016/j.ijpharm.2020.120107.
  4. Mahri, Sohaib ; Rondon, Aurélie ; Wilms, Tobias ; Bosquillon, Cynthia ; Vanbever, Rita.
    Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.
    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 329, p. 1054-1065 (2021). doi:10.1016/j.jconrel.2020.10.034.


  1. Alevra Sarika, Niki ; Payen, Valery ; Fléron, Maximilien ; Ravau, Joachim ; Brusa, Davide ; Najimi, Mustapha ; Pauw, Edwin De ; Eppe, Gauthier ; Mazzucchelli, Gabriel ; Sokal, Etienne ; des Rieux, Anne ; El Taghdouini, Adil.
    Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells.
    In: Cells, Vol. 9, no.6, p. 1357 (2020). doi:10.3390/cells9061357.
  2. Bozzato, Elia ; Bastiancich, Chiara ; Préat, Véronique.
    Nanomedicine: A Useful Tool against Glioma Stem Cells.
    In: Cancers, Vol. 13, no.1 (2020). doi:10.3390/cancers13010009.
  3. Buya Banzenga, Aristote ; Ucakar, Bernard ; Beloqui Garcia, Ana ; Memvanga, Patrick ; Préat, Véronique.
    Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDSs) for senicapoc.
    In: International Journal of Pharmaceutics, Vol. 580, p. 119180 (2020). doi:10.1016/j.ijpharm.2020.119180 (Accepté/Sous presse).
  4. Buya, Aristote Banzenga ; Beloqui Garcia, Ana ; Memvanga, Patrick ; Préat, Véronique.
    Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery.
    In: Pharmaceutics, Vol. 12, no.12, p. 1194 (2020). doi:10.3390/pharmaceutics12121194.
  5. Carradori, Dario ; Labrak, Yasmine ; Miron, Véronique E ; Saulnier, Patrick ; Eyer, Joël ; Préat, Véronique ; des Rieux, Anne.
    Retinoic acid-loaded NFL-lipid nanocapsules promote oligodendrogenesis in focal white matter lesion.
    In: Biomaterials, Vol. 230, p. 119653 [1-11] (2020). doi:10.1016/j.biomaterials.2019.119653.
  6. Dumont, Camille ; Beloqui Garcia, Ana ; Miolane, Cédric ; Bourgeois, Sandrine ; Préat, Véronique ; Fassi, Hatem ; Jannin, Vincent.
    Solid lipid nanocarriers diffuse effectively through mucus and enter intestinal cells - but where is my peptide?.
    In: International journal of pharmaceutics, Vol. 586, p. 119581 (2020). doi:10.1016/j.ijpharm.2020.119581 (Accepté/Sous presse).
  7. Fourniols, Thibaut ; Bastien, Estelle ; Canevat, Alizée ; Feron, Olivier ; Préat, Véronique.
    Inhibition of colorectal cancer-associated fibroblasts by lipid nanocapsules loaded with acriflavine or paclitaxel.
    In: International journal of pharmaceutics, Vol. 584, p. 119337 (2020). doi:10.1016/j.ijpharm.2020.119337 (Accepté/Sous presse).
  8. Huguet-Casquero, Amaia ; Xu, Yining ; Gainza, Eusebio ; Pedraz, Jose Luis ; Beloqui Garcia, Ana.
    Oral delivery of oleuropein-loaded lipid nanocarriers alleviates inflammation and oxidative stress in acute colitis.
    In: International journal of pharmaceutics, Vol. 586, p. 119515 (2020). doi:10.1016/j.ijpharm.2020.119515 (Accepté/Sous presse).
  9. Kandalam, Saikrishna ; De Berdt, Pauline ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Bouzin, Caroline ; Gratpain, Viridiane ; Diogenes, Anibal ; Montero-Menei, Claudia N ; des Rieux, Anne.
    Human dental stem cells of the apical papilla associated to BDNF-loaded pharmacologically active microcarriers (PAMs) enhance locomotor function after spinal cord injury.
    In: International journal of pharmaceutics, Vol. 587, p. 119685 (2020). doi:10.1016/j.ijpharm.2020.119685.
  10. Moura, Rui Pedro ; Pacheco, Catarina ; Pêgo, Ana Paula ; des Rieux, Anne ; Sarmento, Bruno.
    Lipid nanocapsules to enhance drug bioavailability to the central nervous system.
    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 322, p. 390-400 (2020). doi:10.1016/j.jconrel.2020.03.042.
  11. Plaza-Oliver, M ; Beloqui Garcia, Ana ; Santander-Ortega, M J ; Castro-Vázquez, L ; Rodríguez-Robledo, V ; Arroyo-Jiménez, M M ; Préat, Véronique ; Lozano, M V.
    Ascorbyl-dipalmitate-stabilised nanoemulsions as a potential localised treatment of inflammatory bowel diseases.
    In: International journal of pharmaceutics, Vol. 586, p. 119533 (2020). doi:10.1016/j.ijpharm.2020.119533 (Accepté/Sous presse).
  12. Scarcello, Eleonora ; Lambremont, Alexia ; Vanbever, Rita ; Jacques, Pascal ; Lison, Dominique.
    Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese.
    In: PLOS ONE, Vol. 15, no.4, p. e0231634 (2020). doi:10.1371/journal.pone.0231634.
  13. Shahbazi, Mohammad-Ali ; Shrestha, Neha ; Pierchala, Malgorzata Karolina ; Kadumudi, Firoz Babu ; Mehrali, Mehdi ; Hasany, Masoud ; Préat, Véronique ; Leeuwenburgh, Sander ; Dolatshahi-Pirouz, Alireza.
    A self-healable, moldable and bioactive biomaterial gum for personalised and wearable drug delivery.
    In: Journal of Materials Chemistry B, Vol. 8, no.19, p. 4340-4356 (2020). doi:10.1039/c9tb02156f.
  14. Tsakiris, Nikolaos ; Fauvet, Frédérique ; Ruby, Samia ; Puisieux, Alain ; Paquot, Adrien ; Muccioli, Giulio ; Vigneron, Arnaud M ; Préat, Véronique.
    Combined nanomedicines targeting colorectal cancer stem cells and cancer cells.
    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 326, p. 387-395 (2020). doi:10.1016/j.jconrel.2020.07.025.
  15. Xu, Yining ; Bohns-Michalowski, Cécilia ; Beloqui Garcia, Ana.
    Advances in lipid carriers for drug delivery to the gastrointestinal tract.
    In: Current opinion in colloid & interface science, Vol. 52, p. 101414 [1-17 ] (2020). doi:10.1016/j.cocis.2020.101414.
  16. Xu, Yining ; De Keersmaecker, Herlinde ; Braeckmans, Kevin ; De Smedt, Stefaan ; Cani, Patrice D. ; Préat, Véronique ; Beloqui Garcia, Ana.
    Targeted nanoparticles towards increased L cell stimulation as a strategy to improve oral peptide delivery in incretin-based diabetes treatment.
    In: Biomaterials, Vol. 255, p. 120209 [1-12] (2020). doi:10.1016/j.biomaterials.2020.120209.
  17. Xu, Yining ; Shrestha, Neha ; Préat, Véronique ; Beloqui Garcia, Ana.
    Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems.
    In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 322, p. 486-508 (2020). doi:10.1016/j.jconrel.2020.04.006.
  18. Xu, Yining ; Van Hul, Matthias ; Suriano, Francesco ; Préat, Véronique ; Cani, Patrice D. ; Beloqui Garcia, Ana.
    Novel strategy for oral peptide delivery in incretin-based diabetes treatment.
    In: Gut, Vol. 69, no.5, p. 911-919 (2020). doi:10.1136/gutjnl-2019-319146.
  19. Zhao, Mengnan ; van Straten, Demian ; Broekman, Marike L D ; Préat, Véronique ; Schiffelers, Raymond M.
    Nanocarrier-based drug combination therapy for glioblastoma.
    In: Theranostics, Vol. 10, no.3, p. 1355-1372 (2020). doi:10.7150/thno.38147.


  1. Bastiancich, Chiara ; Bozzato, Elia ; Luyten, Urszula ; Danhierr, Fabienne ; Bastiat, Guillaume ; Préat, Véronique.
    Drug combination using an injectable nanomedicine hydrogel for glioblastoma treatment.
    In: International Journal of Pharmaceutics, Vol. 559, p. 220-227 (2019). doi:10.1016/j.ijpharm.2019.01.042.
  2. Boyd, Ben J ; Bergström, Christel A S ; Vinarov, Zahari ; Kuentz, Martin ; Brouwers, Joachim ; Augustijns, Patrick ; Brandl, Martin ; Bernkop-Schnürch, Andreas ; Shrestha, Neha ; Préat, Véronique ; Müllertz, Anette ; Bauer-Brandl, Annette ; Jannin, Vincent.
    Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems.
    In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 137, p. 104967 (2019). doi:10.1016/j.ejps.2019.104967 (Accepté/Sous presse).
  3. Del Vento, Federico ; Vermeulen, Maxime ; Ucakar, Bernard ; Poels, Jonathan ; des Rieux, Anne ; Wyns, Christine.
    Significant Benefits of Nanoparticles Containing a Necrosis Inhibitor on Mice Testicular Tissue Autografts Outcomes.
    In: International journal of molecular sciences, Vol. 20, no.23, p. 5833 [1-18] (2019). doi:10.3390/ijms20235833.
  4. Diaz Iglesias, Yvan ; Wilms, Tobias ; Vanbever, Rita ; Van Bambeke, Françoise.
    Activity of Antibiotics against Staphylococcus aureus in an Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium.
    In: Antimicrobial agents and chemotherapy, Vol. 63, no.7, p. pii: e00602-19 (2019). doi:10.1128/AAC.00602-19.
  5. Freches, Danielle ; Rocks, Natacha ; Patil, Harshad P. ; Perrin, Fabienne ; Van Snick, Jacques ; Vanbever, Rita ; Cataldo, Didier.
    Preclinical evaluation of topically-administered PEGylated Fab’lung toxicity.
    In: International Journal of Pharmaceutcis, (2019).
  6. Ganipineni, Lakshmi Pallavi ; Ucakar, Bernard ; Joudiou, Nicolas ; Riva, Raphaël ; Jérôme, Christine ; Gallez, Bernard ; Danhier, Fabienne ; Préat, Véronique.
    Paclitaxel-loaded multifunctional nanoparticles for the targeted treatment of glioblastoma.
    In: Journal of drug targeting, Vol. 27, no.5-6, p. 614-623 (2019). doi:10.1080/1061186X.2019.1567738.
  7. Kos, Spela ; Lopes, Alessandra ; Préat, Véronique ; Cemazar, Maja ; Lampreht Tratar, Ursa ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Sersa, Gregor ; Vandermeulen, Gaëlle.
    Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma.
    In: PloS one, Vol. 14, no.5, p. e0217762 (2019). doi:10.1371/journal.pone.0217762.
  8. Lloyd, Amy F ; Davies, Claire L ; Holloway, Rebecca K ; Labrak, Yasmine ; Ireland, Graeme ; Carradori, Dario ; Dillenburg, Alessandra ; Borger, Eva ; Soong, Daniel ; Richardson, Jill C ; Kuhlmann, Tanja ; Williams, Anna ; Pollard, Jeffrey W ; des Rieux, Anne ; Priller, Josef ; Miron, Veronique E.
    Central nervous system regeneration is driven by microglia necroptosis and repopulation.
    In: Nature neuroscience, Vol. 22, p. 1046-1052 (2019). doi:10.1038/s41593-019-0418-z.
  9. Lopes, Alessandra ; Feola, Sara ; Ligot, Sophie ; Fusciello, Manlio ; Vandermeulen, Gaëlle ; Préat, Véronique ; Cerullo, Vincenzo.
    Oncolytic adenovirus drives specific immune response generated by a poly-epitope pDNA vaccine encoding melanoma neoantigens into the tumor site.
    In: Journal for immunotherapy of cancer, Vol. 7, no.1, p. 174 (2019). doi:10.1186/s40425-019-0644-7.
  10. Lopes, Alessandra ; Vandermeulen, Gaëlle ; Préat, Véronique.
    Cancer DNA vaccines: current preclinical and clinical developments and future perspectives.
    In: Journal of experimental & clinical cancer research : CR, Vol. 38, no.1, p. 146 (2019). doi:10.1186/s13046-019-1154-7.
  11. Matos, Ana I ; Carreira, Barbara ; Peres, Carina ; Moura, Liane I F ; Conniot, João ; Fourniols, Thibaut ; Scomparin, Anna ; Martínez-Barriocanal, Águeda ; Arango, Diego ; Conde, João P ; Préat, Véronique ; Satchi-Fainaro, Ronit ; Florindo, Helena F.
    Nanotechnology is an important strategy for combinational innovative chemo-immunotherapies against colorectal cancer.
    In: Journal of controlled release : official journal of the Controlled Release Society, (2019). doi:10.1016/j.jconrel.2019.06.017.
  12. O’Driscoll, Caitriona M ; Bernkop-Schnürch, Andreas ; Friedl, Julian D ; Préat, Véronique ; Jannin, Vincent.
    Oral delivery of non-viral nucleic acid-based therapeutics - do we have the guts for this?.
    In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 133, no.133, p. 190-204 (2019). doi:10.1016/j.ejps.2019.03.027.
  13. Sironval, Violaine ; Palmai-Pallag, Mihaly ; Vanbever, Rita ; Huaux, François ; Mejia, Jorge ; Lucas, Stéphane ; Lison, Dominique ; Van Den Brûle, Sybille.
    HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles.
    In: Particle and Fibre Toxicology, Vol. 16, no.35, p. 1-12 (2019). doi:10.1186/s12989-019-0319-z.
  14. Tatic, Natalija ; Rose, Felicity R. A. J. ; des Rieux, Anne ; White, Lisa J.
    Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells.
    In: Scientific Reports, Vol. 9, no. 1, p. 14015 [1-9] (2019). doi:10.1038/s41598-019-50367-x.
  15. Tomar, Jasmine ; Tonnis, Wouter F. ; Patil, Harshad P. ; de boer, Anne H. ; Hagedoorn, Paul ; Vanbever, Rita ; Frijlink, Henderik W. ; Hinrichs, Wouter L.J.
    Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination.
    In: Acta Pharmaceutica Sinica B, Vol. 9, no. 6, p. 1231-1240 (2019). doi:10.1016/j.apsb.2019.05.003.
  16. Tsakiris, Nikolaos ; Papavasileiou, Malamatenia ; Bozzato, Elia ; Lopes, Alessandra ; Vigneron, Arnaud M ; Préat, Véronique.
    Combinational drug-loaded lipid nanocapsules for the treatment of cancer.
    In: International journal of pharmaceutics, Vol. 569, p. 118588 (2019). doi:10.1016/j.ijpharm.2019.118588 (Accepté/Sous presse).
  17. Vanbever, Rita ; Loira Pastoriza, Cristina ; Dauguet, Nicolas ; Hérin, Caroline ; Ibouraadaten, Saloua ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Tyteca, Donatienne ; Huaux, François.
    Cationic Nanoliposomes Are Efficiently Taken up by Alveolar Macrophages but Have Little Access to Dendritic Cells and Interstitial Macrophages in the Normal and CpG-Stimulated Lungs.
    In: Molecular pharmaceutics, Vol. 16, no.5, p. 2048-2059 (2019). doi:10.1021/acs.molpharmaceut.9b00033.
  18. Zamproni, Laura ; Teixeira, Daniela ; Arnaut Alliegro, Amanda ; Longo Maugéri, Ieda ; des Rieux, Anne ; Porcionatto, Marimelia A.
    Decreased viability and neurite length in neural cells treated with chitosan-dextran sulfate nanocomplexes.
    In: Neurotoxicology, Vol. 76, p. 33-43 (2020). doi:10.1016/j.neuro.2019.10.001.


  1. Bastiancich, Chiara ; Bastiat, Guillaume ; Lagarce, Frederic. Gemcitabine and glioblastoma: challenges and current perspectives. In: Drug discovery today, Vol. 23, no. 2, p. 416-423 (2018). doi:10.1016/j.drudis.2017.10.010.
  2. Bastiancich, Chiara ; Lemaire, Laurent ; Bianco, John ; Franconi, Florence ; Danhier, Fabienne ; Préat, Véronique ; Bastiat, Guillaume ; Lagarce, Frederic. Evaluation of lauroyl-gemcitabine-loaded hydrogel efficacy in glioblastoma rat models.. In: Nanomedicine (London, England), (2018). doi:10.2217/nnm-2018-0057.
  3. Carradori, Dario ; Dos Santos, Andreia ; Masquelier, Julien ; Paquot, Adrien ; Saulnier, Patrick ; Eyer, Joël ; Préat, Véronique ; Muccioli, Giulio ; Mingeot-Leclercq, Marie-Paule ; des Rieux, Anne. The origin of neural stem cells impacts their interactions with targeted-lipid nanocapsules: Potential role of plasma membrane lipid composition and fluidity. In: Journal of Controlled Release, Vol. 292, p. 248-255 (2018). doi:10.1016/j.jconrel.2018.11.005.
  4. De Berdt, Pauline ; Bottemanne, Pauline ; Bianco, John ; Al Houayek, Mireille ; diogenes Anibal ; Llyod, Amy ; Gerardo-Nava, Jose ; Brook, Gary A ; Miron, Véronique ; Muccioli, Giulio ; des Rieux, Anne. Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion.. In: Cellular and Molecular Life Sciences, Vol. 75, p. 2843-2856 (2018). doi:10.1007/s00018-018-2764-5.
  5. De Berdt, Pauline ; Bottemanne, Pauline ; Bianco, John ; Alhouayek, Mireille ; Diogenes, Anibal ; Llyod, Amy ; Gerardo-Nava, Jose ; Brook, Gary A. ; Miron, Véronique ; Muccioli, Giulio ; desRieux, Anne. Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion. In: Cellular and Molecular Life Sciences, (2018). doi:10.1007/s00018-018-2764-5 (Accepté/Sous presse).
  6. Desmet, Céline ; Préat, Véronique ; Gallez, Bernard. Nanomedicines and gene therapy for the delivery of growth factors to improve perfusion and oxygenation in wound healing.. In: Advanced Drug Delivery Reviews, Vol. 129, p. 262-284 (2018). doi:10.1016/j.addr.2018.02.001.
  7. Desmet, Céline ; Vandermeulen, Gaëlle ; Bouzin, Caroline ; Lam, Martin ; Préat, Véronique ; Levêque, Philippe ; Gallez, Bernard. EPR monitoring of wound oxygenation as a biomarker of response to gene therapy encoding hCAP-18/LL37 peptide.. In: Magnetic Resonance in Medicine, Vol. 79, no. 6, p. 3267-3273 (2018). doi:10.1002/mrm.26956.
  8. Desmet, Céline Marie ; Tran, Ly Binh An ; Danhier, Pierre ; Gallez, Bernard. Characterization of a clinically used charcoal suspension for in vivo EPR oximetry.. In: Magn Reson Mater Biol Phys, Vol. xx, no. xx, p. 1-8 (2018). doi:10.1007/s10334-018-0704-x.
  9. Ganipineni, Lakshmi Pallavi ; Danhier, Fabienne ; Préat, Véronique. Drug delivery challenges and future of chemotherapeutic nanomedicine for glioblastoma treatment. In: Journal of Controlled Release, Vol. 281, p. 42-57 (2018). doi:10.1016/j.jconrel.2018.05.008.
  10. Ganipineni, Lakshmi Pallavi ; Ucakar, Bernard ; Joudiou, Nicolas ; Bianco, John ; Danhier, Pierre ; Zhao, Mengnan ; Bastiancich, Chiara ; Gallez, Bernard ; Danhier, Fabienne ; Préat, Véronique. Magnetic targeting of paclitaxel-loaded poly(lactic-<em>co</em>-glycolic acid)-based nanoparticles for the treatment of glioblastoma. In: International Journal of Nanomedicine, Vol. 13, p. 4509-4521 (2018). doi:10.2147/ijn.s165184.
  11. Germain, Loïc ; Fuentes, Carlos A. ; van Vuure, Aart W. ; des Rieux, Anne ; Dupont-Gillain, Christine C.3D-printed biodegradable gyroid scaffolds for tissue engineering applications. In: Materials & Design, Vol. 151, p. 113-122 (2018). doi:10.1016/j.matdes.2018.04.037.
  12. Guichard, Marie-Julie ; Kinoo, David ; Aubriot, Anne-Sophie ; Bauwens, Nathalie ; Gougué, Jordane ; Vermeulen, François ; Lebecque, Patrick ; Leal, Teresinha ; Vanbever, Rita. Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum. In: Clinical Science, Vol. 132, p. 1439-1452 (2018). doi:10.1042/cs20180315.
  13. Hardy, Chloé ; Bebelman, S. ; Leloup, Gaëtane ; Hadis, M.A. ; Palin, W.M. ; Leprince, Julian. Investigating the limits of resin-based luting composite photopolymerization through various thicknesses of indirect restorative materials. In: Dental Materials, (2018). doi:10.1016/
  14. Joris, Freya ; De Backer, Lynn ; Van de Vyver, Thijs ; Bastiancich, Chiara ; De Smedt, Stefaan C ; Raemdonck, Koen. Repurposing cationic amphiphilic drugs as adjuvants to induce lysosomal siRNA escape in nanogel transfected cells.. In: Journal of controlled release, Vol. 269, p. 266-276 (2018). doi:10.1016/j.jconrel.2017.11.019.
  15. Kalichuk, Valentina ; Renodon-Cornière, Axelle ; Béhar, Ghislaine ; Carrión, Federico ; Obal, Gonzalo ; Maillasson, Mike ; Mouratou, Barbara ; Préat, Véronique ; Pecorari, Frédéric. A novel, smaller scaffold for Affitins: Showcase with binders specific for EpCAM.. In: Biotechnology and Bioengineering, Vol. 115, p. 290-299 (2018). doi:10.1002/bit.26463 (Soumis).
  16. Lopes, Alessandra ; Vanvarenberg, Kevin ; Kos, Špela ; Lucas, Sophie ; Colau, Didier ; Van den Eynde, Benoît ; Préat, Véronique ; Vandermeulen, Gaëlle. Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma.. In: Scientific reports, Vol. 8, no.1, p. 15732 (2018). doi:10.1038/s41598-018-33933-7.
  17. Lozano, Carmen ; Azcona-Gutiérrez, José Manuel ; Sáenz, Yolanda. Great phenotypic and genetic variation among successive chronic Pseudomonas aeruginosa from a cystic fibrosis patient, collab. Van Bambeke, Françoise. In: PLOS ONE, Vol. 13, no. 9, p. e0204167 (2018). doi:10.1371/journal.pone.0204167.
  18. Lyoussi, Badiaa ; Cherkaoui Tangi, Khadija ; Morel, Nicole ; Haddad, Mohamed ; Quetin-Leclercq, Joëlle. Evaluation of cytotoxic effects and acute and chronic toxicity of aqueous extract of the seeds of (Poiret) Link (subsp. ) in rodents.. In: Avicenna Journal of Phytomedicine, Vol. 8, no.2, p. 122-135 (2018). doi:10.22038/ajp.2017.23177.1859.
  19. Montigaud, Yoann ; Ucakar, Bernard ; Krishnamachary, Balaji ; Bhujwalla, Zaver M ; Feron, Olivier ; Préat, Véronique ; Danhier, Fabienne ; Gallez, Bernard ; Danhier, Pierre. Optimized acriflavine-loaded lipid nanocapsules as a safe and effective delivery system to treat breast cancer.. In: International journal of pharmaceutics, Vol. 551, no.1-2, p. 322-328 (2018). doi:10.1016/j.ijpharm.2018.09.034.
  20. Shrestha, Neha ; Bouttefeux, Oriane ; Vanvarenberg, Kevin ; Lundquist, Patrik ; Cunarro, Juan ; Tovar, Sulay ; Khodus, Georgiy ; Andersson, Ellen ; Keita, Åsa V ; Gonzalez Dieguez, Carlos ; Artursson, Per ; Préat, Véronique ; Beloqui Garcia, Ana. The stimulation of GLP-1 secretion and delivery of GLP-1 agonists via nanostructured lipid carriers.. In: Nanoscale, Vol. 10, p. 603-613 (2018). doi:10.1039/c7nr07736j.
  21. Xu, Yining ; Carradori, Dario ; Al Houayek, Mireille ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique ; Beloqui Garcia, Ana. Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.. In: Molecular Pharmaceutics, Vol. 15, p. 108-115 (2018). doi:10.1021/acs.molpharmaceut.7b00742.
  22. Xu, Yining ; Carradori, Dario ; Al Houayek, Mireille ; Muccioli, Giulio ; Cani, Patrice D. ; Préat, Véronique ; Beloqui Garcia, Ana. Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.. In: Molecular pharmaceutics, Vol. 15, no.1, p. 108-115 (2018). doi:10.1021/acs.molpharmaceut.7b00742.
  23. Zhao, Mengnan ; Danhier, Fabienne ; Bastiancich, Chiara ; Joudiou, Nicolas ; Ganipineni, Lakshmi Pallavi ; Tsakiris, Nikolaos ; Gallez, Bernard ; des Rieux, Anne ; Jankovski, Aleksandar ; Bianco, John ; Préat, Véronique. Post-resection treatment of glioblastoma with an injectable nanomedicine-loaded photopolymerizable hydrogel induces long-term survival.. In: International journal of pharmaceutics, Vol. 548, no. 1, p. 522-529 (2018). doi:10.1016/j.ijpharm.2018.07.033.


  1. Beloqui Garcia, Ana ; Brayden, David J ; Artursson, Per ; Préat, Véronique ; des Rieux, Anne.
    A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.
    In: Nature Protocols (Online) : recipes for researchers, Vol. 12, no.7, p. 1387-1399 (2017). doi:10.1038/nprot.2017.041.     
  2. Bianco, John ; Bastiancich, Chiara ; Jankovski, Aleksandar ; des Rieux, Anne ; Préat, Véronique ; Danhier, Fabienne.
    On glioblastoma and the search for a cure: where do we stand?
    In: Cellular and Molecular Life Sciences, Vol. 74, no. 13, p. 2451-2466 (2017). doi:10.1007/s00018-017-2483-3.
  3. Bianco, John ; Carradori, Dario ; Deumens, Ronald ; des Rieux, Anne.
    Rapid Serum-Free Isolation of Oligodendrocyte Progenitor Cells from Adult Rat Spinal Cord.
    In: Stem Cell Reviews, (2017). doi:10.1007/s12015-017-9742-4. 
  4. Carradori, Dario ; Eyer, Joel ; Saulnier, Patrick ; Préat, Véronique ; des Rieux, Anne.
    The therapeutic contribution of nanomedicine to treat neurodegenerative diseases via neural stem cell differentiation.
    In: Biomaterials, Vol. 123, p. 77-91 (2017). doi:10.1016/j.biomaterials.2017.01.032.
  5. Dugernier, Jonathan ; Hesse, Michel ; Vanbever, Rita ; Depoortere, Virginie ; Roeseler, Jean ; Michotte, JeanBernard ; Laterre, Pierre-François ; Jamar, François ; Reychler, Gregory.
    SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. In: Pharmaceutical Research, Vol. 34, no. 2, p. 290-300 (2017). doi:10.1007/s11095-016-2061-7.
  6. Freches, Danielle ; Patil, Harshad Padmanabh ; Machado Franco, Maria ; Uyttenhove, Catherine ; Heywood, Sam ; Vanbever, Rita.
    PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.. In: International Journal of Pharmaceutics, Vol. 521, no.1-2, p. 120-129 (2017). doi:10.1016/j.ijpharm.2017.02.021.
  7. Furtado, N ; Pirson, L ; Edelberg, Hélène ; Miranda, L ; Loira Pastoriza, Cristina ; Préat, Véronique ; Larondelle, Yvan ; Andre, C.
    Pentacyclic Triterpene Bioavailability: An Overview of In Vitro and In Vivo Studies.
    In: Molecules (Print Archive Edition), Vol. 22, no.400 (march 2017). doi:10.3390/molecules22030400. 
  8. Guichard, Marie-Julie ; Patil, Harshad Padmanabh ; Koussoroplis, Salome Juliette ; Wattiez, Ruddy ; Leal, Teresinha ; Vanbever, Rita.
    Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy.
    In: International Journal of Pharmaceutics, Vol. 524, no.1-2, p. 159-167 (2017). doi:10.1016/ j.ijpharm.2017.03.057.
  9. Guichard, Marie-Julie; Leal, Teresinha; Vanbever Rita.
    PEGylation, an approach for improving the pulmonary delivery of biopharmaceuticals
    In : Current Opinion in Colloid & Interface Science, Vol. 31, p. 43-50 (2017)
  10. Kandalam, Saikrishna ; Sindji, Laurence ; Delcroix, Gaëtan J-R ; Violet, Fabien ; Garric, Xavier ; André, Emilie M ; Schiller, Paul C ; Venier-Julienne, Marie-Claire ; des Rieux, Anne ; Guicheux, Jérôme ; Montero-Menei, Claudia N.
    Pharmacologically active microcarriers delivering BDNF within a hydrogel: Novel strategy for human bone marrowderived stem cells neural/neuronal differentiation guidance and therapeutic secretome enhancement.
    In: Acta Biomaterialia, Vol. 49, p. 167-180 (2017). doi:10.1016/j.actbio.2016.11.030.
  11. Kos, Spela ; Vanvarenberg, Kevin ; Dolinsek, Tanja ; Cemazar, Maja ; Jelenc, Jure ; Préat, Véronique ; Sersa, Gregor ; Vandermeulen, Gaëlle.
    Gene electrotransfer into skin using noninvasive multi-electrode array for vaccination and wound healing.
    In: Bioelectrochemistry, Vol. 114, p. 33-41 (2017). doi:10.1016/j.bioelechem.2016.12.002.
  12. Peres, Carina ; Matos, Ana I ; Conniot, João ; Sainz, Vanessa ; Zupančič, Eva ; Silva, Joana M ; Graça, Luís ; Sá Gaspar, Rogério ; Préat, Véronique ; Florindo, Helena F.
    Poly(lactic acid)-based particulate systems are promising tools for immune modulation.
    In: Acta Biomaterialia, Vol. 48, p. 41-57 (2017). doi:10.1016/j.actbio.2016.11.012. 
  13. Vanbever, Rita; Mitragotri, Samir
    Therapeutic opportunities for polymer-drug conjugates to deliver small molecules and proteins.
    In : Current Opinion in Colloid & Interface Science, Vol. 31, p. A1-A2 (2017)
  14. Vermeulen, Maxime ; Poels, Jonathan ; De Michele, Francesca ; des Rieux, Anne ; Wyns, Christine.
    Restoring Fertility with Cryopreserved Prepubertal Testicular Tissue: Perspectives with Hydrogel Encapsulation, Nanotechnology, and Bioengineered Scaffolds. In: Annals of Biomedical Engineering, (2017). doi:10.1007/s10439-017-1789-5 (Accepté/ Sous presse).
  15. Viswanath, Aiswarya ; Vanacker, Julie ; Germain, Loïc ; Leprince, Julian ; Diogenes, Anibal ; Shakesheff, Kevin M ; White, Lisa J ; des Rieux, Anne.
    Extracellular matrix-derived hydrogels for dental stem cell delivery.
    In: Journal of Biomedical Materials Research. Part A, Vol. 105, no.1, p. 319-328 (2017). doi:10.1002/jbm.a.35901.
  16. Zamproni, Laura N ; Mundim, Mayara V ; Porcionatto, Marimelia A ; des Rieux, Anne.
    Injection of SDF-1 loaded nanoparticles following traumatic brain injury stimulates neural stem cell recruitment.
    In: International Journal of Pharmaceutics, Vol. 519, no.1-2, p. 323-331 (2017). doi:10.1016/j.ijpharm.2017.01.036.


  1. Bastiancich C., Vanvarenberg K., Ucakar B., Pitorre M., Bastiat G., Lagarce F., Préat V., Danhier F.
    Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma. 
    J. Control. Release, 225, 283-293. [Journal Impact Factor : 7.441 (in 2015)] - PMID : 26829100
  2. Bastiancich C., Danhier P., Préat V., Danhier F.
    Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma.
    J. Control. Release. [Journal Impact Factor : 7.441 (in 2015)] - PMID : 27693428
  3. Beloqui A., Memvanga P.B., Coco R., Reimondez-Troitiño S., Alhouayek M., Muccioli G.G., Alonso M.J., Csaba N., de la Fuente M., Préat V.
    A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease.
    Colloids Surf. B Biointerfaces, 143, 327-335. [Journal Impact Factor : 3.902 (in 2015)] - PMID : 27022873
  4. Beloqui A., Solinís M.Á., Rodríguez-Gascón A., Almeida A.J., Préat V.
    Nanostructured lipid carriers: Promising drug delivery systems for future clinics.
    Nanomedicine, 12, 143–161. [Journal Impact Factor : 6.155 (in 2014)] - PMID : 26410277
  5. Beloqui A., Alhouayek M., Carradori D., Vanvarenberg K., Muccioli G.G., Cani P.D., Préat V.
    A Mechanistic Study on Nanoparticle-Mediated Glucagon-Like Peptide-1 (GLP-1) Secretion from Enteroendocrine L Cells.
    Mol. Pharm., 13(12), 4222-4230. [Journal Impact Factor : 4.342 (in 2015)]
  6. Beloqui A., des Rieux A., Préat V.
    Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier.
    Adv. Drug Deliv. Rev. , 106(Pt B), 242-255. [Journal Impact Factor : 15.606 (in 2015)] - PMID : 27117710
  7. Bianco J., De Berdt P., Deumens R., des Rieux A.
    Taking a bite out of spinal cord injury: do dental stem cells have the teeth for it?
    Cell Mol. Life Sci., 73(7), 1413-1437. [Journal Impact Factor : 5.694 (in 2015)] - PMID : 26768693
  8. Bouttefeux O., Beloqui A., Preat V.
    Delivery of Peptides Via the Oral Route: Diabetes Treatment by Peptide-Loaded Nanoparticles.
    Curr. Pharm. Des., 22(9), 1161-1176. [Journal Impact Factor : 3.052 (in 2015)] - PMID : 26675223
  9. Carradori D., Saulnier P., Préat V., des Rieux A., Eyer J.
    NFL-lipid nanocapsules for brain neural stem cell targeting in vitro and in vivo.
    J. Control. Release, 238, 253-262. [Journal Impact Factor: 7.441 (in 2015)] - PMID : 27503706
  10. Chereddy K.K., Vandermeulen G., Préat V.
    PLGA based drug delivery systems: Promising carriers for wound healing activity. 
    Wound Repair Regen., 24(2):223-236. [Journal Impact Factor : 2.628 (in 2015)] - PMID : 26749322
  11. Corbet C., Ragelle H., Pourcelle V., Vanvarenberg K., Marchand-Brynaert J., Préat V., Feron O.
    Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method.
    J. Control. Release, 223:53-63.[Journal Impact Factor : 7.441 (in 2015)] - PMID : 26699426
  12. Dalheim M.Ø., Vanacker J., Najmi M.A., Aachmann F.L., Strand B.L., Christensen B.E.
    Efficient functionalization of alginate biomaterials.
    Biomaterials, 80, 146-156. [Journal Impact Factor : 8.387 (in 2015)] - PMID : 26708091
  13. Danhier F.
    To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?
    J. Control. Release., 244(Pt A), 108-121. [Journal Impact Factor: 7.441 (in 2015)] - PMID : 27871992
  14. Desoubeaux G., Reichert J.M., Sleeman M., Reckamp K.L., Ryffel B., Adamczewski J.P., Sweeney T.D., Vanbever R., Diot P., Owen C.A., Page C., Lerondel S., Le Pape A., Heuze-Vourc'h N.
    Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France.
    MAbs, 8(6), 999-1009. [Journal Impact Factor: 4.161 (in 2015)] - PMID : 27266390
  15. Dugernier J., Reychler G., Wittebole X., Roeseler J., Depoortere V., Sottiaux T., Michotte J.B., Vanbever R., Dugernier T., Goffette P., Docquier M.A., Raftopoulos C., Hantson P., Jamar F., Laterre P.F.
    Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study.
    Ann. Intensive Care, 6(1), 73. [Journal Impact Factor: 3.447 (in 2014)] - PMID : 27447788
  16. Gartziandia O., Egusquiaguirre S.P., Bianco J., Pedraz J.L., Igartua M., Hernandez R.M., Préat V., Beloqui A.
    Nanoparticle transport across in vitro olfactory cell monolayers.
    Int. J. Pharm., 499, 81-89. [Journal Impact Factor : 3.994 (in 2015)] - PMID : 26721725
  17. Guada M., Beloqui A., Kumar M.N., Préat V., Dios-Viéitez M.D., Blanco-Prieto M.J.
    Reformulating cyclosporine A (CsA): More than just a life cycle management strategy.
    J. Control. Release., 225, 269-282. [Journal Impact Factor : 7.441 (in 2015)] - PMID : 26829101
  18. Guada M., Beloqui A., Alhouayek M., Muccioli G.G., Dios-Viéitez Mdel C., Préat V., Blanco-Prieto M.J.
    Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease. 
    Int. J. Pharm., 503(1-2), 196-198.  [Journal Impact Factor : 3.994 (in 2015)] - PMID : 26972380
  19. Jully V., Mathot F., Moniotte N., Préat V., Lemoine D.
    Mechanisms of antigen adsorption onto an aluminum-hydroxide adjuvant evaluated by high-troughput screening. 
    J. Pharm. Sci., 105(6), 1829-1836. [Journal Impact Factor : 2.590 (in 2014)] - PMID : 27238481
  20. Kos S., Vanvarenberg K., Dolinsek T., Cemazar M., Jelenc J., Préat V., Sersa G., Vandermeulen G.
    Gene electrotransfer into skin using noninvasive multi-electrode array for vaccination and wound healing.
    Bioelectrochemistry,114, 33-41. [Journal Impact Factor: 3.556 (in 2015)] - PMID : 28006672
  21. Kos S., Blagus T., Cemazar M., Lampreht Tratar U., Stimac M., Prosen L., Dolinsek T., Kamensek U., Kranjc S., Steinstraesser L., Vandermeulen G., Préat V., Sersa G.
    Electrotransfer parameters as a tool for controlled and targeted gene expression in skin.
    Mol. Ther. Nucleic Acids, 5(8), e356. [Journal Impact Factor: 3.556 (in 2015)] - PMID : 27574782 [reprint PDF ] - UCL only - Copyright owned by the publisher - Contributing Research Group : ADDB
  22. Lambricht L., Lopes A., Kos S., Sersa G., Préat V., Vandermeulen G.
    Clinical potential of electroporation for gene therapy and DNA vaccine delivery.
    Expert Opin. Drug Deliv., 13(2), 295-310. [Journal Impact Factor : 4.116 (in 2014)] - PMID : 26578324
  23. Lambricht L., Vanvarenberg K., De Beuckelaer A., Van Hoecke L., Grooten J., Ucakar B., Lipnik P., Sanders N.N., Lienenklaus S., Préat V., Vandermeulen G.
    Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.
    Mol. Ther., 24(9), 1686-1696. [Journal Impact Factor : 6.938 (in 2015)] - PMID : 27434590
  24. Luo T., Magnusson J., Préat V., Frédérick R., Alexander C., Bosquillon C., Vanbever R.
    Synthesis and In Vitro Evaluation of Polyethylene Glycol-Paclitaxel Conjugates for Lung Cancer Therapy.
    Pharm. Res., 33(7), 1671-1681. [Journal Impact Factor : 3.420 (in 2014)] - PMID : 26984129
  25. Luo T., Loira-Pastoriza C., Patil H.P., Ucakar B., Muccioli G.G., Bosquillon C., Vanbever R.
    PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma. 
    J. Control. Release, 239, 62-71. [Journal Impact Factor : 7.441 (in 2015)]
  26. Poels J., Abou-Ghannam G., Decamps A., Leyman M., des Rieux A., Wyns C.
    Transplantation of testicular tissue in alginate hydrogel loaded with VEGF nanoparticles improves spermatogonial recovery.
    J. Control Release, 234, 79-89. [Journal Impact Factor : 7.441 (in 2015)] - PMID: 27189137
  27. Ragelle H., Vanvarenberg K., Vandermeulen G., Préat V.
    Chitosan nanoparticles for SiRNA delivery in vitro.
    Methods Mol. Biol., 1364, 143-150. - PMID : 27730820
  28. Randolph L.D., Steinhaus J., Möginger B., Gallez B., Stansbury J., Palin W.M., Leloup G., Leprince J.G.
    Photopolymerization of highly filled dimethacrylate-based composites using Type I or Type II photoinitiators and varying co-monomer ratios.
    Dent Mater., 32(2), 136-148. [Journal Impact Factor : 3.931 (in 2015)] - PMID : 26719130
  29. Randolph L.D., Palin W.M., Leloup G., Leprince J.G.
    Filler characteristics of modern dental resin composites and their influence on physico-mechanical properties.
    Dent Mater., 32(12), 1586-1599. [Journal Impact Factor : 3.931 (in 2015)] - PMID : 26719130
  30. Stanga S., Zanou N., Audouard E., Tasiaux B., Contino S., Vandermeulen G., René F., Loeffler J.P., Clotman F., Gailly P., Dewachter I., Octave J.N., Kienlen-Campard P.
    APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.
    FASEB J., 30(5) 1696-1711. [Journal impact factor : 5.299 (in 2015)] - PMID : 26718890
  31. Taccola G., Doyen P.J., Damblon J., Dingu N., Ballarin B., Steyaert A., des Rieux A., Forget P., Hermans E., Bosier B., Deumens R.
    A new model of nerve injury in the rat reveals a role of Regulator of G protein Signaling 4 in tactile hypersensitivity.
    Exp. Neurol., 286, 1-11. [Journal Impact Factor: 4.657 (in 2015)] - PMID : 27641322
  32. Thwala L.N., Beloqui A., Csaba N.S., González-Touceda D., Tovar S., Dieguez C., Alonso M.J., Préat V.
    The interaction of protamine nanocapsules with the intestinal epithelium: A mechanistic approach.
    J. Control. Release, 243, 109-120. [Journal Impact Factor : 7.441 (in 2015)] - PMID : 27720993


  1. Bruffaerts N., Pedersen L.E., Vandermeulen G., Préat V., Stockhofe-Zurwieden N., Huygen K., Romano M.
    Increased B and T Cell Responses in M. bovis Bacille Calmette-Guérin Vaccinated Pigs Co-Immunized with Plasmid DNA Encoding a Prototype Tuberculosis Antigen.
    PLoS One, 10(7), e0132288. [Journal Impact Factor : 3.234 (in 2014)] - PMID : 26172261
  2. Chereddy K.K., Lopes A., Koussoroplis S., Payen V., Moia C., Zhu H., Sonveaux P., Carmeliet P. des Rieux A. Vandermeulen G. Préat V.
    Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds.
    Nanomedicine, 11, 1975-1984. [Journal Impact Factor : 6.155 (in 2014)] - PMID : 26238081
  3. Cuvelier B., Eloy P., Loira-Pastoriza C., Ucakar B., Sanogo A.A., Dupont-Gillain C., Vanbever R. 
    Minimal amounts of dipalmitoylphosphatidylcholine improve aerosol performance of spray-dried temocillin powders for inhalation.
    Int. J. Pharm., 495(2), 981-990. [Journal Impact Factor : 3.650 (in 2014)] - PMID : 26456267
  4. Danhier F., Danhier P., De Saedeleer C.J., Fruytier A.C., Schleich N., des Rieux A., Sonveaux P., Gallez B2, Préat V4.
    Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors.
    Int. J. Pharm., 479(2), 399-407. [Journal Impact Factor : 3.650 (in 2014) - PMID : 25578367
  5. De Berdt P., Vanacker J., Ucakar B., Elens L., Diogenes A., Leprince J.G., Deumens R., des Rieux A.
    Dental Apical Papilla as Therapy for Spinal Cord Injury.
    J. Dent. Res., 94(11), 1575-1581. [Journal Impact Factor : 4.139 (in 2014) - PMID : 26341974
  6. Desmet C.M., Djurkin A., Dos Santos-Goncalvez A.M., Dong R., Kmiec M.M., Kobayashi K., Rychert K., Beun S., Leprince J.G., Leloup G., Levêque P., Gallez B. 
    Tooth retrospective dosimetry using Electron Paramagnetic Resonance: Influence of irradiated dental composites.
    PLoS One. 2015 Jun 30;10(6):e0131913. [Journal Impact Factor : 3.234 (in 2014) - PMID : 26125565
  7. Fourniols T., Randolph L.D., Staub A., Vanvarenberg K., Leprince J.G., Préat V., des Rieux A., Danhier F.
    Temozolomide-loaded photopolymerizable PEG-DMA-based hydrogel for the treatment of glioblastoma.
    J. Control. Release, 210, 95-104. [Journal impact factor: 7.705 (in 2014)] - PMID : 25982679
  8. Germain L., De Berdt P., Vanacker J., Leprince J., Diogenes A., Jacobs D., Vandermeulen G., Bouzin C., Préat V., Dupont-Gillain C., des Rieux A.
    Fibrin hydrogels to deliver dental stem cells of the apical papilla for regenerative medicine.
    Regen Med., 10(2), 153-167. [Journal impact factor: 2.786 (in 2014)] - PMID : 25835480
  9. Jully V., Moniotte N., Mathot F., Lemoine D., Préat V.
    Development of a high-throughput screening platform to study the adsorption of antigens onto aluminum-containing adjuvants.
    J. Pharm. Sci., 104(2), 557-565. [Journal impact factor: 2.590 (in 2014)] - PMID : 25470455
  10. Ragelle H., Colombo S., Pourcelle V., Vanvarenberg K., Vandermeulen G., Bouzin C., Marchand-Brynaert J., Feron O., Foged C., Préat V.
    Intracellular siRNA delivery dynamics of integrin-targeted, PEGylated chitosan-poly(ethylene imine) hybrid nanoparticles: A mechanistic insight. 
    J. Control. Release, 211, 1-9. [Journal impact factor: 7.705 (in 2014)] - PMID : 25989603
  11. Schleich N., Danhier F., Préat V.
    Iron oxide-loaded nanotheranostics: Major obstacles to in vivo studies and clinical translation.
    J. Control. Release, 198C, 35-54. [Journal Impact Factor: 7.261 (in 2013)] - PMID : 25481448
  12. Silva J.M., Zupancic E., Vandermeulen G., Oliveira V.G., Salgado A., Videira M., Gaspar M., Graca L., Préat V., Florindo H.F.
    In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model.
    J. Control. Release, 198, 91-103. [Journal Impact Factor: 7.261 (in 2013)] - PMID: 25483429
  13. Tesic N., Kamensek U., Sersa G., Kranjc S., Stimac M., Lampreht U., Préat V., Vandermeulen G., Butinar M., Turk B., Cemazar M.
    Endoglin (CD105) Silencing Mediated by shRNA Under the Control of Endothelin-1 Promoter for Targeted Gene Therapy of Melanoma.
    Mol. Ther. Nucleic Acids, 4, e239. PMID : 25942402
  14. Vandermeulen G., Vanvarenberg K., De Beuckelaer A., De Koker S., Lambricht L., Uyttenhove C., Reschner A.? Vanderplasschen A., Grooten J., Préat V.
    The site of administration influences both the type and the magnitude of the immune response induced by DNA vaccine electroporation.
    Vaccine, 33(28), 3179-3185. [Journal Impact Factor : 3.624 (in 2014)] - PMID : 25980430


  1. Beloqui A., Solinís M.Á., des Rieux A., Préat V., Rodríguez-Gascón A.
    Dextran-protamine coated nanostructured lipid carriers as mucus-penetrating nanoparticles for lipophilic drugs.
    Int. J. Pharm., 468(1-2), 105-111. [Journal impact factor: 3.785 (in 2013)] - PMID : 24746410
  2. Beloqui A., Coco R., Memvanga P.B., Ucakar B., des Rieux A., Préat V.
    pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease
    Int. J. Pharm., 473(1-2), 203-212. [Journal impact factor: 3.785 (in 2013)] - PMID : 25014369
  3. Chereddy K.K., Her C.H., Comune M., Moia C. Lopes A., Porporato P.E., Vanacker J., Lam M.C., Steinstraesser L., Sonveaux P., Zhu H., Ferreira L.S., Vandermeulen G., Préat V.
    PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.
    J. Control. Release., 194C, 138-147. [Journal impact factor: 7.261 (in 2013)] - PMID : 25173841
  4. Danhier F., Kouhé T.T., Duhem N., Ucakar B., Staub A., Draoui N., Feron O., Préat V.
    Vitamin E-based micelles enhance the anticancer activity of doxorubicin.
    Int. J. Pharm., 476(1-2), 9-15.  [Journal impact factor: 3.785 (in 2013)] - PMID : 25245548
  5. Danhier F., Ucakar B., Vanderhaegen M.L., Brewster M.E., Arien T., Préat V.
    Nanosuspension for the delivery of a poorly soluble anti-cancer kinase inhibitor. 
    Eur. J. Pharm. Biopharm., 88(1), 252-260. [Journal impact factor: 3.785 (in 2013)] - PMID : 24859391 
  6. des Rieux A., De Berdt P., Ansorena E., Ucakar B., Damien J, Schakman O, Audouard E, Bouzin C, Auhl D, Simón-Yarza T, Feron O, Blanco-Prieto MJ, Carmeliet P, Bailly C, Clotman F, Préat V.
    Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord.
    J Biomed Mater Res A. 2014 Jul;102(7):2345-2355. [Journal impact factor: 2.841(in 2013)] - PMID : 23946111 
  7. Duhem N., Danhier F., Préat V.
    Vitamin E-based nanomedicines for anti-cancer drug delivery.
    J. Control. Release, 182C, 33-44. [Journal Impact Factor : 7.261(in 2013)] - PMID : 24631865
  8. Koussoroplis S.J., Paulissen G., Tyteca D., Goldansaz H., Todoroff J., Barilly C., Uyttenhove C., Van Snick J., Cataldo D., Vanbever R.
    PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract. 
    J. Control Release, 187C, 91-100. [Journal Impact Factor : 7.261 (in 2013)] - PMID : 24845126
  9. Lambricht L., De Berdt P., Vanacker J., Leprince J., Diogenes A., Goldansaz H., Bouzin C., Préat V., Dupont-Gillain C., des Rieux A.
    The type and composition of alginate and hyaluronic-based hydrogels influence the viability of stem cells of the apical papilla.
    Dent Mater., 30(12), e349-e361. [Journal Impact Factor : 4.160] - PMID : 25182372
  10. Leprince J.G., Palin W.M., Vanacker J., Sabbagh J., Devaux J., Leloup G.
    Physico-mechanical characteristics of commercially available bulk-fill composites.
    J. Dent., 42(8), 993-1000. [Journal impact factor: 2.840 (in 2013)] - PMID : 24874951
  11. Loira-Pastoriza C., Todoroff J., Vanbever R.
    Delivery strategies for sustained drug release in the lungs.
    Adv. Drug Deliv. Rev., 75C, 81-91. [Journal impact factor: 12.707 (in 2013)] - PMID : 24915637
  12. Memvanga P.B., Mbinze J.K., Rozet E., Hubert P., Préat V., Marini R.D.
    Development of a liquid chromatographic method for the simultaneous quantification of curcumin, β-arteether, tetrahydrocurcumin and dihydroartemisinin. Application to lipid-based formulations.
    J. Pharm. Biomed. Anal., 88C:447-456. [Journal Impact Factor : 2.829 (in 2013)] - PMID : 24184380
  13. Palin W.M., Hadis M.A., Leprince J.G., Leloup G., Boland L., Fleming G.J., Krastl G., Watts D.C.
    Reduced polymerization stress of MAPO-containing resin composites with increased curing speed, degree of conversion and mechanical properties.
    Dent. Mater., 30(5), 507-516. [Journal Impact Factor : 4.160] - PMID : 24629734
  14. Ragelle H., Riva R., Vandermeulen G., Naeye B., Pourcelle V., Le Duff CS., D'Haese C5, Nysten B., Braeckmans K., De Smedt SC., Jérôme C., Préat V.
    Chitosan nanoparticles for siRNA delivery: Optimizing formulation to increase stability and efficiency.
    J. Control. Release, 17, 54-63. [Journal Impact Factor : 7.261 (in 2013)] - PMID : 24389132
  15. Randolph L.D., Palin W.M., Bebelman S., Devaux J., Gallez B., Leloup G., Leprince J.G.
    Ultra-fast light-curing resin composite with increased conversion and reduced monomer elution
    Dent. Mater., 30(5), 594-604. [Journal Impact Factor : 4.160 (in 2013)] - PMID : 24679406
  16. Randolph L.D., Palin W.M., Watts D.C., Genet M., Devaux J., Leloup G., Leprince J.G.
    The effect of ultra-fast photopolymerisation of experimental composites on shrinkage stress, network formation and pulpal temperature rise.
    Dent. Mater., 30(11), 1280-1289. [Journal Impact Factor : 4.160 (in 2013)] - PMID: 25261362
  17. Schleich N., Po C., Jacobs D., Ucakar B., Gallez B., Danhier F., Préat V.
    Comparison of active, passive and magnetic targeting to tumors of multifunctional paclitaxel/SPIO-loaded nanoparticles for tumor imaging and therapy.
    J. Control. Release, 194C:82-91. [Journal Impact Factor : 7.261 (in 2013)] - PMID : 25178270
  18. Setbon H.M., Devaux J., Iserentant A., Leloup G., Leprince J.G.
    Influence of composition on setting kinetics of new injectable and/or fast setting tricalcium silicate cements.
    Dent Mater., 30(12), 1291-1303. [Journal Impact Factor : 4.160] - PMID: 25443159
  19. Steinstraesser L., Lam M.C., Jacobsen F., Porporato P.E., Chereddy K.K., Becerikli M., Stricker I., Hancock R.E., Lehnhardt M., Sonveaux P., Préat V., Vandermeulen G.
    Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing
    Mol. Ther., 22(4), 734-742. [Journal Impact Factor : 6.425 (in 2013)] - PMID : 24394186   
  20. Ungaro F., Vanbever R.
    Improving the efficacy of inhaled drugs for severe lung diseases: Emerging pulmonary delivery strategies.
    Adv. Drug Deliv. Rev.,75, 1-2. [Journal Impact Factor : 12.707 (in 2013)] - PMID: 25109852
  21. Vanacker J., Viswanath A., De Berdt P., Everard A., Cani P.D., Bouzin C., Feron O., Diogenes A., Leprince J.G., des Rieux A.
    Hypoxia modulates the differentiation potential of stem cells of the apical papilla.
    J. Endodont., 40(9), 14 10-1418. [Journal Impact Factor : 2.788 (in 2013)] - PMID: 25146023
  22. Vandermeulen G., Uyttenhove C., De Plaen E., Van den Eynde B.J., Préat V.
    Intramuscular electroporation of a P1A-encoding plasmid vaccine delays P815 mastocytoma growth.
    Bioelectrochemistry, 100, 112-118. [Journal Impact Factor : 2.788 (in 2013)] - PMID: 24342164


  1. Ansorena E., De Berdt P., Ucakar B., Simón-Yarza T., Jacobs D., Schakman O., Jankovski A., Deumens R., Blanco-Prieto M.J., Préat V., des Rieux A.
    Injectable alginate hydrogel loaded with GDNF promotes functional recovery in a hemisection model of spinal cord injury.
    Int. J. Pharm., 455(1-2), 148-158. [Journal impact factor: 3.785] - PMID : 23523733
  2. Alonso-Sande M., des Rieux A., Fievez V., Sarmento B., Delgado A., Evora C., Remuñán-López C., Préat V., Alonso M.J. 
    Development of PLGA-Mannosamine nanoparticles as oral protein carriers
    Biomacromolecules, 14(11), 4046-4052. [Journal impact factor: 5.788] - PMID : 24131254
  3. Beloqui A., Solinís M.Á., Gascón A.R., Del Pozo-Rodríguez A., des Rieux A., Préat V.
    Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier
    J. Control. Release, 166(2), 115-123. [Journal impact factor : 7.261] - PMID : 23266764
  4. Beloqui A., Coco R., Alhouayek M., Solinís M.A., Rodríguez-Gascón A., Muccioli G.G., Préat V.
    Budesonide-loaded nanostructured lipid carriers reduce inflammation in murine DSS-induced colitis.
    Int. J. Pharm., 454(2), 775-783. [Journal impact factor : 3.785] - PMID : 23694806
  5. Blagus T., Markelc B., Cemazar M., Kosjek T., Preat V., Miklavcic D., Sersa G.
    In vivo real-time monitoring system of electroporation mediated control of transdermal and topical drug delivery.
    J. Control Release, 172(3), 862-871. [Journal impact factor : 7.261] - PMID : 24113487
  6. Cajot S., Schol D., Danhier F., Préat V., Gillet De Pauw M.C., Jérôme C.
    In vitro investigations of smart drug delivery systems based on redox-sensitive cross-linked micelles
    Macromol. Biosci., 13(12), 1661-1670. [Journal impact factor : 3.650 (in 2012)] - PMID : 24339277
  7. Chereddy K.K., Coco R., Memvanga P.B., Ucakar B., des Rieux A., Vandermeulen G., Préat V.
    Combined effect of PLGA and curcumin on wound healing activity.
    J. Control. Release, 171(2), 208-215. Journal impact factor: 7.261] - PMID : 23891622
  8. Coco R., Plapied L., Pourcelle V., Jérôme C., Brayden D.J., Schneider Y.J., Préat V.
    Drug delivery to inflamed colon by nanoparticles: comparison of different strategies.
    Int. J. Pharm., 440(1), 3-12. [Journal Impact Factor : 3.785] - PMID : 22820482
  9. Crokart N., Danhier F., Daugimont L., Gonçalves N., Jordan B.F., Grégoire V., Feron O., Bouquet C., Gallez B., Préat V.
    Potentiation of radiotherapy by a localized antiangiogenic gene therapy.
    Radiother Oncol.,107(2), 252-258. [Journal Impact Factor : 4.857] - PMID : 23623728
  10. des Rieux A., Pourcelle V., Cani P.D., Marchand-Brynaert J., Préat V.
    Targeted nanoparticles with novel non-peptidic ligands for oral delivery.
    Adv. Drug Deliv. Rev., 65, 6, 833-844. [Journal Impact Factor : 12.707] - PMID : 23454185
  11. Koussoroplis S.J., Heywood S., Uyttenhove C., Barilly C., Van Snick J., Vanbever R.
    Production, purification and biological characterization of mono-PEGylated anti-IL-17A antibody fragments
    Int. J. Pharm., 454(1), 107-115. [Journal Impact Factor : 3.785] - PMID : 23850622
  12. Koussoroplis S.J., Vanbever R.
    Peptides and proteins : pulmonary absorption
    in : Encyclopedia of Pharmaceutica Science and Technology, Fourth edition. pp. 2607-2618
  13. Memvanga P.B., Coco R., Préat V.
    An oral malaria therapy: Curcumin-loaded lipid-based drug delivery systems combined with β-arteether.
    J. Control. Release, 172(3), 904-913. [Journal Impact Factor : 7.261] - PMID : 24021359
  14. Memvanga P.B., Eloy P., Gaigneaux E.M., Préat V.
    In vitro lipolysis and intestinal transport of β-arteether-loaded lipid-based drug delivery systems.
    Pharm Res., 30(10), 2694-2705. [Journal Impact Factor : 3.952] - PMID : 23739990
  15. Neyrinck A.M., Alligier M., Memvanga P.B., Névraumont E., Larondelle Y., Préat V., Cani P.D., Delzenne N.M.
    Curcuma longa Extract Associated with White Pepper Lessens High Fat Diet-Induced Inflammation in Subcutaneous Adipose Tissue
    PLoS One, 8(11):e81252. [Journal impact factor : 3.534] - PMID : 24260564
  16. Ragelle H., Vandermeulen G., Préat V.
    Chitosan-based siRNA delivery systems
    J. Control. Release, 172(1), 207-218. Journal impact factor: 7.261] - PMID : 23965281
  17. Reschner A., Scohy S., Vandermeulen G., Daukandt M., Jacques C., Michel B., Nauwynck H., Xhonneux F., Préat V., Vanderplasschen A., Szpirer C. 
    Use of Staby® technology for development and production of DNA vaccines free of antibiotic resistance gene.
    Hum. Vaccin. Immunother., 9(10). 2203-2210. Journal impact factor: 2.131)] - PMID : 24051431
  18. Schleich N., Sibret P., Danhier P., Ucakar B., Laurent S., Muller R.N., Jérôme C., Gallez B., Préat V., Danhier F.
    Dual anticancer drug/superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging.
    Int. J. Pharm., 447(1-2):94-101.  [Journal Impact Factor : 3.785] - PMID : 23485340 
  19. Silva J.M., Videira M., Gaspar R., Préat V., Florindo H.F.
    Immune system targeting by biodegradable nanoparticles for cancer vaccines
    J. Control Release. 168(2), 179-199. [Journal Impact Factor : 7.261] - PMID : 23524187
  20. Silva J.M., Zupancic E., C. Peres C., Silva L.C., Gaspar R., Préat V., Florindo H.F.
    Immunomodulation against microbial pathogens through dendritic cells in : Microbial pathogens and strategies for combating them: science, technology and education, Volume 3, A. Méndez-Vilas, Ed, pp. 1686-1705. Contributing Research Group : FARG
  21. Todoroff J., Lemaire M.M, Fillee C, Jurion F, Renauld JC, Huygen K, Vanbever R.
    Mucosal and Systemic Immune Responses to Mycobacterium tuberculosis Antigen 85A following Its Co-Delivery with CpG, MPLA or LTB to the Lungs in Mice.
    PLoS One., 8(5):e63344. [Journal Impact Factor : 3.534] - PMID : 23675482
  22. Todoroff J., Ucakar B., Inglese M., Vandermarliere S., Fillee C., Renauld J.C., Huygen K., Vanbever R.
    Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery.
    Eur. J. Pharm. Biopharm., 84(1):40-48. [Journal Impact Factor : 4.245] - PMID : 23238272
  23. Zorec B., Préat V., Miklavčič D., Pavšelj N.
    Active enhancement methods for intra- and transdermal drug delivery: A review
    Zdravniski Vestnik, 82 (5), 339-356. 


  1. Danhier F., Danhier P., Magotteaux N., De Preter G., Ucakar B., Karroum O., Jordan B., Gallez B., Préat V.
    Electron paramagnetic resonance highlights that the oxygen effect contributes to the radiosensitizing effect of Paclitaxel
    PLoS One. 2012;7(7):e40772. [Journal impact factor : 3.730] - PMID : 22808261
  2. Danhier F., Pourcelle V., Marchand-Brynaert J., Jérôme C., Feron O., Préat V.
    Targeting of tumor endothelium by RGD-Grafted PLGA-nanoparticles
    Methods Enzymol., 508, Chapter 8, 157-175. [Journal impact factor: 2.002] - PMID : 22449925
  3. Danhier F., Ansorena E., Silva J.M., Coco R., Le Breton A., Préat V.
    PLGA-based nanoparticles: An overview of biomedical applications
    J. Control Release., 161(2), 505-522. [Journal impact factor: 7.633] - PMID : 22353619
  4. Danhier F., Le Breton A., Préat V.
    RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis.
    Mol. Pharm., 9(11), 2961-2973.  [Journal impact factor: 4.570] - PMID : 22967287
  5. Dasnoy S., Le Bras V., Préat V., Lemoine D.
    High-throughput assessment of antigen conformational stability by ultraviolet absorption spectroscopy and its application to excipient screening.
    Biotechnol. Bioeng., 109, 502-516. [Journal Impact Factor : 3.648]
  6. Duhem N., Rolland J., Riva R., Guillet P., Schumers J.M., Jérôme C., Gohy J.F., Préat V.
    Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs
    Int. J. Pharm., 423, 452-460. [Journal Impact Factor : 3.458]
  7. Fernandes C., Fievez L., Neyrinck A., Delzenne N., Bureau F., Vanbever R.
    Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages
    Biochem. Biophys. Res. Commun., 420, 857-861. [Journal Impact Factor : 2.406] - PMID : 22469470
  8. Memvanga P., Préat V.
    Formulation design and in vivo antimalarial evaluation of lipid-based drug delivery systems for oral delivery of β-arteether
    Eur. J. Pharm. Biopharm., 82, 112–119. [Journal Impact Factor : 3.826] - PMID : 22609572
  9. Porporato PE, Payen VL, De Saedeleer CJ, Préat V, Thissen JP, Feron O, Sonveaux P.
    Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice
    Angiogenesis, 15(4), 581-592. [Journal Impact Factor : 3.972] - PMID : 22660894
  10. Rolland J., Guillet P., Schumers M., Duhem N., Préat V., Gohy J.F
    Polyelectrolyte Complex Nanoparticles from Chitosan and Poly(acrylic acid) and Polystyrene-block-Poly(acrylic acid)
    J. Polym. Sci. Pol. Chem., 50, 4484–4493. [Journal Impact Factor : 3.543]
  11. Vanacker J., Luyckx V., Dolmans M.M., Des Rieux A., Jaeger J., Van Langendonckt A., Donnez J., Amorim C.A.
    Transplantation of an alginate-matrigel matrix containing isolated ovarian cells: first step in developing a biodegradable scaffold to transplant isolated preantral follicles and ovarian cells.
    Biomaterials, 33(26), 6079-6085. [Journal Impact Factor : 7.604] - PMID : 22658800
  12. Vandermeulen G., Athanasopoulos T., Trundley A., Foster K., Préat V., Yáñez-Muñoz R.J., Dickson G.
    Highly potent delivery method of gp160 envelope vaccine combining lentivirus-like particles and DNA electrotransfer
    J. Control. Release., 159(3): 376-383. [Journal impact factor: 7.633] - PMID : 22310089
    [Reprint PDF ] - (UCL only - Copyright owned by the publisher) - Contributing Research Group : FARG


  1. Dasnoy S., Dezutter N., Lemoine D., Le Bras V., Préat V.
    High-throughput screening of excipients intended to prevent antigen aggregation at air-liquid interface.
    Pharm. Res., 2011, 28, 1591-1605.  [Journal Impact Factor : 4.093] - PMID : 21400018
  2. Daugimont L., Vandermeulen G., Defresne F., Bouzin C., Mir L., Bouquet C., Feron O., Préat V.
    Antitumoral and antimetastatic effect of antiangiogenic plasmids in B13 melanoma: higher efficiency of the recombinant disintegrin domain of ADAM15
    Eur. J. Pharm. Biopharm., 78, 314-319. [Journal Impact Factor : 4.269] - PMID : 21316447
  3. De Laporte L., des Rieux A., Tuinstra H., Zelivyanskaya M., De Clercq N., Postov A., Préat V., Shea L.
    Vascular endothelial growth factor and fibroblast growth factor 2 delivery from spinal cord bridges to enhance angiogenesis following injury
    J. Biomed. Mater. Res. Part A, 98A, 373-382. [Journal Impact Factor : 2.625] - PMID : 21630429des Rieux A., Ucakar B., Kaishusha Mupendwa Billy Paul, Colau D., Feron O., Carmeliet P., Préat V.
    3D systems delivering VEGF to promote angiogenesis for tissue engineering
    J. Controlled Release, 150, 272-278. [Journal Impact Factor : 6.499] - PMID : 21130820
  4. Driessens G., Nuttin L., Gras A., Maetens J., Mievis S., Schoore M., Velu T., Tenenbaum L., Préat V.,
    Bruyns C.

    Development of a successful antitumor therapeutic model combining in vivo dendritic cell vaccination with tumor irradiation and intratumoral GM-CSF delivery.
    Cancer Immunol. Immunother., 60, 273-281.  [Journal Impact Factor : 3.701] - PMID : 21076828
  5. Estella-Hermoso de Mendoza A., Préat V., Mollinedo F., Blanco-Prieto M.J.
    In vitro and in vivo efficacy of edelfosine-loaded lipid nanoparticles against glioma
    J. Control. Release, 156, 421-426. Journal Impact Factor : 6.499]. - PMID : 21821074
  6. Fernandes C.A., Fievez L., Ucakar B., Neyrinck A.M., Fillee C., Huaux F., Delzenne N.M., Bureau F., Vanbever R.
    Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice.
    Am. J. Physiol. Lung Cell Mol. Physiol.,300, L354-361. [Journal Impact Factor : 3.662] - PMID : 21131399
  7. Freichels H., Danhier F., Préat V., Lecomte P., Jérôme C.
    Fluorescent labeling of degradable poly(lactide-co-glycolide) for cellular nanoparticles tracking in living cells.
    Int. J. Artif. Organs., 34, 152-160. [Journal Impact Factor : 1.861] - PMID : 21374567
  8. Mitragotri S., Vanbever R.
    Converting innovative colloids into potent drug delivery carriers : Opportunities and challenges (Editorial overview)
    Curr. Opin. Coll. Interface Sci., 16, 169-170. [Journal Impact Factor : 8.010]
  9. Plapied L., Duhem N., des Rieux A., Préat V.
    Fate of polymeric nanocarriers for oral drug delivery
    Curr. Opin. Colloid Interface Sci., 16, 228-237. [Journal Impact Factor : 8.010]- DOI : 10.1016/j.cocis.2010.12.005
  10. Riva R., Ragelle H., des Rieux A., Duhem N., Jérôme C., Préat V.
    Chitosan and Chitosan derivatives in drug delivery and tissue engineering
    in Advances in Polymer Science 244, Chitosan for biomaterials II, Eds R. Jayakumar, M. Prabaharan, R.A.A. Muzzarelli, pp. 19-44. IISN 0065-3195. [Journal Impact Factor : 3.890]
  11. Todoroff J., Vanbever R.
    Fate of nanomedicines in the lungs
    Curr. Opin. Colloid Interface Sci., 16, 246-254. [Journal Impact Factor : 8.010] - DOI : 10.106/j.cocis.2011.03.001
  12. Vandermeulen G., Marie C., Scherman D., Préat V.
    New Generation of Plasmid Backbones Devoid of Antibiotic Resistance Marker for Gene Therapy Trials
    Mol. Ther. 19, 1942-1949.  [Journal Impact Factor : 6.873] PMID: 21878901 
  13. Verrax J., Defresne F., Lair F., Vandermeulen G., Rath G., Dessy C., Préat V., Feron O.
    Delivery of Soluble VEGF Receptor 1 (sFlt1) by Gene Electrotransfer as a New Antiangiogenic Cancer Therapy.
    Mol. Pharm., 8, 701-708.  [Journal Impact Factor : 4.782] - PMID : 21548585 
    [Reprint PDF] - (UCL only - Copyright owned by the publisher) - Contributing Research Group : GTOX/FARG


  1. Danhier F., Ucakar B., Magotteaux N., Brewster M. Préat V.
    Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621
    International Journal of Pharmaceutics, 392: 20-28 [I.F. 3.607]
  2. Danhier F., Feron O., Préat V.
    To exploit the tumor microenvironment : passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
    J. Control Release, 148(2), 135-146. [I.F. 7.164]
  3. Daugimont L., Baron N., Vandermeulen G., Pavselj N., Miklavcic D., Jullien M.C., Cabodevila G., Mir L., Préat V.
    Hollow microneedle arrays for intradermal drug delivery and DNA electroporation
    Journal of Membrane Biology, 236: 117-125 [I.F. 2.189]
  4. Fievez V., Plapied L., Plaideau C., Legendre D., des Rieux A., Pourcelle V., Freichels H., Jérôme C., Marchand J., Préat V., Schneider Y.J.
    In vitro identification of targeting ligands of human M cells by phage display
    International Journal of Pharmaceutics, 394: 35-42   [I.F. 3.607]
  5. Marie C., Vandermeulen G., Quiviger M., Richard M., Préat V., Scherman D.
    pFARs, plasmids free of antibiotic resistance markers, display high-level transgene expression in muscle, skin and tumour cells
    Journal of Gene Medicine, 12: 323-332
  6. Mignet N., Vandermeulen G., Pembouong G, Largeau C., Thompson B., Spanedda M.V., Wasungu L., Rols M.P., Bessodes M., Bureau M.F., Préat V., Scherman D.
    Cationic and anionic lipoplexes inhibit gene transfection by electroporation in vivo, Journal of Gene Medicine, 12: 491-500 [I.F. 2.968]
  7. Plapied L., Vandermeulen G., Vroman B., des Rieux A.
    Bioadhesive nanoparticles of fungal chitosan for oral DNA delivery
    International Journal of Pharmaceutics, 398: 210-218 [I.F. 3.607]
  8. Patton S., Brain J., Davies L., Fiegel J., Gumbleton M., Kim K.J., Sakagami M., Vanbever R., Ehrhardt C.
    The particle has Landd-characterizing the fate of inhalec pharmaceuticals
    J. Aerosol. Med. Pulm. Drug Deliv., 23, 71-87. [I.F.: 1.824]
  9. Staes E., Rozet E., Ucakar B., Hubert Ph., Préat V.
    Validation of a method for the quantitation of ghrelin and unacylated ghrelin by HPLC
    Journal of Pharmaceutical and Biomedical Analysis, 51: 633-639  [I.F. 2.629]
  10. Staes E., Absil P.A., Lins L., Brasseur R., Deleu M., Lecouturier N., Fievez V., des Rieux A., Mingeot-Leclercq M.P., Raussens V., Préat V.
    Acylated and unacylated ghrelin binding to membranes and to ghrelin receptor: towards a better understanding of the underlying mechanisms
    BBA-Biomembranes, 1798, 2102-2113 [I.F. 3.998]


  1. Charlier N., Driesschaert B., Wauthoz N., Beghein N., Préat V., Amighi K., Marchand-Brynaert J., Gallez B.
    Nano-emulsions of fluorinated trityl radicals as sensors for EPR oximetry
    Journal of Magnetic Resonance, 197: 176-180 [I.F. 2.438]
  2. Danhier F. Lecouturier N., Vroman B., Jérôme C., Marchand-Brynaert J., Feron O., Préat V.
    Paclitaxel-loaded PEGylated PLGA-based nanoparticles : In vitro and in vivo evaluation
  3. Journal of Controlled Release, 133: 11-17 [I.F. 5.690]
  4. Danhier F., Vroman B., Lecouturier N., Crokart N., Pourcelle V., Freichels H., Jérôme C, Marchand-Brynaert J., Feron O., Préat V.
    Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with Paclitaxel
    Journal of Controlled Release, 140: 166-173 [I.F. 5.690]
  5. Danhier F., Magotteaux N., Ucakar B., Lecouturier N., Brewster M., Préat V.
    Novel self-assembling PEG-p-CL-co-TMC) polymeric micelles as safe and effective delivery system for Paclitaxel
    European Journal of Pharmaceuticas and Biopharmaceutics, 73: 230-238 [I.F. 3.344]
  6. des Rieux A., Shikanov A., Shea L.
    Fibrin hydrogels for non-viral vector delivery in vitro
    Journal of Controlled Release, 136: 148-154 [I.F. 5.690]
  7. Ducreux J., Tyteca D., Ucakar B., Medts T., Crocker P., Courtoy P., Vanbever R.
    PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages
    Bioconjugate Chemistry, 29: 295-303 [I.F. 4.584]
  8. Ducreux J., Crocker P., Vanbever R.
    Analysis of sialoadhesin expression on mouse alveolar macrophages, Immunology Letters, 124: 77-80 [I.F. 2.858]
  9. Fernandes C., Vanbever R.
    Preclinical models for pulmonary drug delivery
    Expert opinion on Drug Delivery, 6: 1231-1245
  10. Fievez V., Plapied L., des Rieux A., Pourcelle V., Freichels H., Wascotte V., Vanderhaeghen M.-L., Jérôme C., Vanderplasschen A., Marchand-Brynaert J., Schneider Y.J., Préat V.
    Tarteting nanoparticles to M cells with non-peptidic ligands for oral vaccination
    European Journal of Pharmaceutics and Biopharmaceutics, 73: 16-24 [I.F. 3.344]
  11. Lubamba B., Lebacq J., Lebecque P., Vanbever R., Leonard A., Wallemacq P., Leal T.
    Airway delivery of low-dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice
    American Journal of Respiratory and critical care medicine, 179: 1022-1028 [I.F. 9.792]
  12. Ni J., Nolte B., Vandermeulen G., Préat V., Scherman D., Schirmacher V., Fournier Ph.
    Ear Pinna: A priviliged DNA electroporation site for inducing strong Th1 immune responses
    The Open Cancer Immunology Journal, 2: 1-13
  13. Préat V., Vandermeulen G., Daugimont L., Wascotte V.
    Ionophorèse et électroporation, administration cutanée de médicaments et d'ADN
    Actualité Chimique, 327-328: 81-84
  14. Rives C., des Rieux A., Zelivyanskaya M., Stock S., Lowe W., Shea L.
    Layered PLG scaffolds for in vivo plasmid delivery
    Biomaterials, 30: 394-401 [I.F. 6.646]
  15. Rouxhet L., Dinguizli M., Latere Dwan'Isa J.P., Ould-Ouali L., Twaddle P., Nathan A., Brewster M.E., Rosenblatt J., Ariên A., Préat V.
    Monoglyceride-based self assembling copolymers as carriers for poorly water-soluble drugs
    International of Pharmaceutics, 382: 244-253 [I.F. 3.061]
  16. Slutter B., Plapied L., Fievez V., Alonso-Sande M., des Rieux A., Schneider Y.J., Van Riet E., Jiskoot W., Préat V.
    Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination
    Journal of Controlled Release, 138: 113-121 [I.F. 5.690]
  17. Vandermeulen G., Richiardi H., Escriou V., Ni J., Fournier P., Schirmacher V., Scherman D., Préat V.
    Skin-specific promoters for genetic immunisation by DNA electroporation
  18. Vaccine, 27: 4272-4277 [I.F. 3.298]
  19. Vandermeulen G., Daugimont L., Richiardi H., Vanderhaeghen M.L., Lecouturier N., Ucakar B., Préat V.
    Effect of tape stripping and adjuvants on immune response after intradermal DNA electroporation
    Pharmaceutical Research, 26: 1745-1751 [I.F. 4.024]


  1. André F., Gehl J., Sersa G., Préat V., Hojman P., Eriksen J., Golzio M., Cemazar M., Pavselj N., Rols M.P., Miklavcic D., Neumann E., Teissié J., Mir L.
    Efficiency of High- and Low-Voltage pulse combinations for gene electrotransfer in muscle; liver, tumor and skin, Human Gene Therapy, 19: 1261-1271 [I.F.4104]
  2. Ducreux J., Vanbever R., Croker P.
    The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following, Bioconjugate chemistry, 19: 2088-2094 [I.F. 4.584]
  3. Herkenne C., Alberti I., Naik A., Kalia Y.N., Mathy F.X., Préat V., Guy R.H.
    In vivo methods for the assessment of topical drug bioavailability, Pharmaceutical Research, 25: 87-103 [I.F. 4.024]
  4. Latere Dwan'Isa J.P., Rouxhet L., Brewster M.E., Préat V., Ariën A.
    Spontaneously self assembled micelles form poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization
    Die Pharmazie, 63 : 235-240
  5. Minne A., Huaux F., Jaworska J., Rha R.D., Hamelmann E., Vanbever R.
    Safety evaluation of pulmonary influenza vaccination in healthy and "asthmatic" mice, Vaccine, 26: 2360-2368 [I.F. 3.298]
  6. Minne A., Boireau H., Horta J.M., Vanbever R.
    Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients, European Journal of Pharmaceutics and Biopharmaceutics, 70:839-844 [I.F. 3.344]
  7. Vandermeulen G., Daugimont L., Préat V.
    DNA transfer in the skin in : Dermatologic, cosmeceutic and cosmetic development - Development and novel approaches - Ed. H. Walters, M. Roberts, Chapter 33:537-555
  8. Wascotte V., Rozet E., Salvaterra A., Hubert Ph. Jadoul M. Guy R.H., Préat V.
    Non-invasive diagnosis and monitoring of chronic kidney disease by reverse iontophoresis of urea in vivo, European Journal of Pharmaceutics and Biopharmaceutics, 69: 1077-1082 [I.F. 3.344]


  1. Beghein N., Rouxhet L., Dinguizli M., Brewster ME, Arien A, Préat V, Habib JL, Gallez B.
    Characterization of self-assembling copolymers in aqueous solutions using Electron Paramagnetic Resonance and Fluorescence spectroscopy, Journal of Controlled Release, 117: 196-203 [I.F. 4.756]
  2. Begu S., Bochot A., L. Choisnard, Couvreur P., Duchêne D., Edwards-Lévy F., Fattal E., Gèze A., Ponchel G., Préat V., Tourné-Péteilh C., Wouessidjewe D.
    Pharmacie galénique - Formulation et technologie pharmaceutique - Chapitre 8 : formes galéniques en développement, pp. 251-289 - P. Wherlé, Marloine
  3. des Rieux A., Fievez V., Momtaz M., Detrembleur C., Alonso-Sande M., Van Gelder J., Cauvin A., Schneider Y.J., Préat V.
    Helodermin-loaded nanoparticles: Characterization and transport across an in vitro model of the follicle-associated epithelium, Journal of Controlled Release, 118: 294-302 [I.F. 4.756]
  4. des Rieux A., Fievez V., Théate I., Mastd J., Préat V., Schneider Y.J.
    An improved in vitro model of human intestinal follicle-associated epithelium to study nanoparticle transport by M cells, European Journal of Pharmaceutical Sciences, 30: 380-391[I.F. 3.127]
  5. Ducreux J., Vanbever R.
    Crucial biopharmaceutical issues facing macromolecular candidates for inhalation : the role of macrophages in pulmonary protein clearance, Respiratory Drug Delivery Europe, 31-41
  6. Dwan’Isa Latere J.P., Rouxhet L., Préat V., Brewster M.E., Arien A.
    Prediction of drug solubility in amphiphilic di-block copolymer micelles: the role of polymer-drug compatibility
    Die Pharmacie, 62, 7, 499-504 [I.F. 0.775]
  7. Garinot M., Fievez V., Pourcelle V., Stoffelbach F., des Rieux A., Plapied L., Theate I., Freichels H., Jerôme C., Marchand Brynaert J., Schneider Y.J., Préat V.
    PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination, Journal of Controlled Release, 120: 195-204 [I.F. 4.756]
  8. Mathot F., Schanck F., Van Bambeke F., Arien A., Noppe M., Brewster M., Préat V.
    Passive diffusion of polymeric surfactants across lipid bilayers, Journal of Controlled Release, 120, 79-87 [I.F. 4.756]
  9. Mathot F., des Rieux A., Ariën A., Schneider Y.J., Brewster M., Préat V.
    Transport mechanisms of mmePEG750P(CL-co-TMC) polymeric micelles across the intestinal barrier, Journal of Controlled Release, 124: 134-143 [I.F. 4756]
  10. Minne A., Louahed J., Mehauden S., Baras B., Renauld J.C., Vanbever R.
    The delivery site of a monovalent influenza vaccine within the respiratory tract impacts on the immune response, Immunology, 122: 316-325 [I.F. 3.398]
  11. Minne A., Jaworska J., Gerhold K., Ahrens B., Avagyan A., Vanbever R., Matricardi P.M., Schmidt A.C., Hamelmann E.
    Intranasal delivery of whole influenza vaccine prevents subsequent allergen-induced sensitization and airway hyper-reactivity in mice, Clinical and Experimental Allergy, 37:1250-1258 [I.F. 3.729]
  12. Pavselj N., Préat V., Miklavcic D.
    A numerical model of skin electropermeabilization based on in vivo experiments, Annals of Biomedical Engineering, 35:2138-2144 [I.F. 2.346]
  13. Pourcelle V., Devouge S., Garinot M., Préat V., Marchand-Brynaert J.
    PCL-PEG-Based nanoparticles grafted with GRDGS peptide: preparation and surface analysis by XPS, Biomacromolecules, 8: 3977-3983 [I.F. 4.169]
  14. Rozet E., Wascotte V., Lecouturier N., Préat V., Dewé W., Boulanger B., Hubert P.
    Improvement of the decision efficiency of the accuracy profile by means of a desirability function for analytical methods validation: application to a diacetyl-monoxime colorimetric assay used for the determination or urea in transdermal iontophoretic extracts, Analytica Chimica Acta, 591, 239-247 [I.F. 3.186]
  15. Vandermeulen G., Staes E., Vanderhaeghen M.L., Bureau M.F., Scherman D., Préat V.
    Optimisation of intradermal DNA electrotransfer for immunisation, Journal of Controlled Release, 124: 81-87 [I.F. 4.756]
  16. Vroman B., Mazza M., Fernandez M., Jérôme R., Préat V.
    Copolymers of e-caprolactone and quaternized e-caprolactone as gene carriers, Journal of Controlled Release, 118: 136-144 [I.F. 4.756]
  17. Vroman B., Ferreira I., Jerome C., Jérôme R., Préat V.
    PEGylated quaternized copolymer/DNA complexes for gene delivery, International Journal of Pharmaceutics, 344: 88-95 [I.F. 2.408]
  18. Wascotte V., Delgado-Charro M.B., Rozet E., Wallemacq P., Hubert P., Guy R.H., Préat V.,
    Monitoring of Urea and Potassium by Reverse Iontophoresis In Vitro, Pharmaceutical Research, 24, 1131-1137 [I.F. 3.441]
  19. Wascotte V., Caspers P., de Sterke J., Jadoul M., Guy R.H., Préat V.
    Assessment of the "Skin Reservoir" of Urea by Confocal Raman Microspectroscopy and Reverse Iontophoresis in vivo, Pharmaceutical Research, 24: 1897-1901
    [I.F. 3.441]


  1. Mathot F., Van Beijsterveldt L., Préat V., Brewster M., Arien A.
    Intestinal uptake and biodistribution of novel polymeric micelles after oral administration, Journal of Controlled Release, 111:47-55
    [I.F. 4.012]
  2. Charlier N., Préat V., Gallez B.
    Evaluation of lipid-based carrier systems and inclusion complexes of diethyldithiocarbamate-iron to trap nitric oxide in biological systems, Magnetic Resonance in Medicine, 55: 215-218
    [I.F. 3.427]
  3. Vandermeulen G., Rouxhet L., Arien A., Brewster M.E., Préat V.
    Encapsulation of amphotericin B in poly(ethylene glycol)-block-poly(epsilon-caprolactone-co-trimethylenecarbonate) polymeric micelles, International journal of Pharmaceutics, 309: 234-240
    [I.F. 2.212]
  4. Préat V., Wascotte V.
    Topical delivery by iontophoresis in handbook of cosmetic science and technology, Second edition, ed. Paye M., Barel A., Maibach H. pp.189-200
  5. Préat V., Roland-Marcelle N., Van den Abeele B.
    Histoire de la pharmacie galénique: L'art de préparer les médicaments de Galien à nos jours.
  6. des Rieux A., Fievez V., Garinot M., Schneider Y.J., Préat V.
    Nanoparticles as potential oral delivery systems of proteins and vaccines : a mechanistic approach, Journal of Controlled Release, 116:1-27
    [I.F. 4.012]


  1. des Rieux A., Ragnarsson E., Gullberg E., Préat V., Schneider Y.J., Artursson P.
    Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium, European Journal of Pharmaceutical Sciences, 25: 455-465
    [I.F. 2.347]
  2. Latere Dwan'Isa J., Dinguizli M., Préat V., Arien A., Brewster M.
    Qualitative prediction of solubilization of highly hydrophobic drugs in block copolymer micelles, Journal of Controlled Release, 101: 366-368
    [I.F. 3.696]
  3. Mathy F.X., Ntivunwa D., Verbeeck R.K., Préat V.
    Fluconazole distribution in rat dermis following intravenous and topical application: a microdialysis study, Journal of Pharmaceutical Sciences, 94:770-780
    [I.F. 2.237]
  4. Mathy F.X., Lombry C., Verbeeck R.K., Préat V.
    Study of the percutaneous penetration of flurbiprofen by cutaneous and subcutaneous microdialys after iontophoretic delivery in rat, Journal of Pharmaceutical Sciences, 94:144-152
    [I.F. 2.237]
  5. Musaji A., Meite M., Detalle L., Franquin S., Cormont F., Préat V., Izui S., Coutelier J.P.
    Enhancement of autoantibody pathogenicity by viral infections in mouse models of anemia and thrombocytopenia, Autoimmunity Reviews, 4: 247-252
    [I.F. 3.091]
  6. Ould-Ouali L., Noppe M., Langlois X., Willems B., Te Riele P., Timmerman P., Brewster M., Ariën, A., Préat V.
    Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone, Journal of Controlled Release, 102:657-668
    [I.F. 3.696]
  7. Pasvlej N., Préat V.
    DNA electrotransfer into the skin using a combination of one high- and one low-voltage pulse, Journal of Controlled Release, 106:407-415
    [I.F. 3.696]
  8. Vanbever R.
    Performance-driven, pulmonary delivery of systemically acting drug, Drug discovery today: technologies, 2:39-46
    [I.F. 7.755]


  1. Bosquillon C., Préat V., Vanbever R.
    Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats, Journal of Controlled Release, 96:233-244
    [I.F. 3.297]
  2. Bosquillon C., Rouxhet P.G., Ahimou F., Simon D., Culot C., Préat V., Vanbever R.
    Aerosolization properties, surface composition and physical state of spray-dried protein powders, Journal of Controlled Release, 99:357-367
    [I.F. 3.297]
  3. Codrons V., Vanderbist F., Ucakar B., Préat V., Vanbever R.
    Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs, Journal of Pharmaceutical Sciences, 93:1241-1252
    [I.F. 2.180]
  4. Denet A.R., Vanbever R., Préat V.
    Skin electroporation for transdermal and topical delivery, Advanced Drug Delivery Reviews, 56:659-674
    [I.F. 7.763]
  5. Dujardin N., Préat V.
    Delivery of DNA to skin by electroporation, In: Methods in Molecular Biology, 245:215-226
  6. Lombry C., Edwards D.E., Préat V., Vanbever R.
    Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules, American Journal of Physiology - Lung Cellular and Molecular Physiology, 286:L1002-L1008
    [I.F. 3.939]
  7. Lombry C., Marteleur A., Arras M., Lison D., Louahed J., Renauld J.C., Préat V., Vanbever R.
    Local and systemic immune responses to intratracheal instillation of antigen and DNA vaccines in mice, Pharmaceutical Research, 21:127-135
  8. Ould-Ouali L., Ariën A., Rosenblatt J., Nathan A., Twaddle P., Matalenas T., Borgia M., Arnold S., Préat V.
    Biodegradable self-assembling PEG-copolymer as vehicle for poorly water-soluble drugs, Pharmaceutical Research, 21:1581-1590
    [I.F. 2.325]
  9. Préat V.
    Noninvasive lithium monitoring, Clinical Chemistry, 50:1966-1967
  10. [I.F. 6.501]


  1. Codrons V., Vanderbist F., Verbeeck R.K., Arras M., Lison D., Préat V., Vanbever R.
    Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats, Journal of Pharmaceutical Sciences, 92:938-950
    [I.F. 2.070]
  2. Denet A.R., Préat V.
    Transdermal Delivery of timolol by electroporation through human skin, Journal of Controlled Release, 88:253-262
    [I.F. 3.298]
  3. Denet A.R., Ucakar B., Préat V.
    Transdermal delivery of timolol and atenolol using electroporation and iontophoresis in combination : a mechanistic approach, Pharmaceutical Research, 20:1946-1951
    [I.F. 2.609]
  4. Mathy F.X., Vroman B., Ntivunwa D., De Winne A.J., Verbeeck R.K., Préat V.
    On-line determination of fluconazole in blood and dermal rat microdialysates by microbore high-performance liquid chromatography, Journal of Chromatography B , 787:323-331 [I.F. 2.085]
  5. Mathy F.X., Denet A.R., Vroman B., Clarys P., Barel A., Verbeeck R.K., Préat V.
    In vivo tolerance assesment of skin after insertion of subcutaneous and cutaneous microdialysis probes in rats, Skin Pharmacology and Applied Skin Physiology, 16:18-27
    [I.F. 1.529]
  6. Préat V., Vanbever R.
    Skin electroporation for transdermal and topical drug delivery.
    In: Transdermal Drug Delivery, RH Guy & JHadgraft ed, Marcel Dekker, 227-254
  7. Vanbever R.
    Optimization of dry powder aerosols for systemic drug delivery.
    In: Optimization of aerosol drug delivery, Leon Gradon & Jan Marijnissen ed., Kluwer Academic Publishers,


  1. Dujardin N., Staes E., Kalia Y., Clarys P., Guy R., Préat V.
    In vivo assessment of skin electroporation using square wave pulses, Journal of Controlled Release, 79:219-227
     [I.F. 3.131]
  2. Lombry C., Bosquillon C., Préat V., Vanbever R.
    Confocal imaging of rat lungs following intratracheal delivery of dry powders or solutions of fluorescent probes, Journal of Controlled Release , 83:331-341
     [I.F. 3131]


  1. Benoit M.A., Ribet C., Distexhe J., Hermand D., Letesson J.J., Vandenhaute J., Gillard J.
    Studies on the potential of microparticles entrapping pDNA-poly(aminoacids) complexes as vaccine delivery systems, Journal of Drug Targeting , 9:253-266
  2. Bosquillon C., Lombry C., Préat V., Vanbever R.
    Comparison of particle sizing techniques in the case of inhalation dry powders
    Journal of Pharmaceutical Sciences , 90:2032-2041 [I.F. 2.117]
  3. Bosquillon C., Lombry C., Préat V., Vanbever R.
    Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance, Journal of Controlled Release, 70:329-339
    [I.F. 2626]
  4. Dujardin N., Van der Smissen P., Préat V.
    Topical gene transfer into rat skin using electroporation, Pharmaceutical Research , 18:61-66
    [I.F. 2.801]
  5. Mathy F.X., Préat V., Verbeeck R.K.
    Validation of subcutaneous microdialysis sampling for pharmacokinetic studies of flurbiprofen in the rat, Journal of Pharmaceutical Sciences, 90:1897-1906
    [I.F. 2117]
  6. Préat V.
    Administration de médicaments et de gènes par électrotransfert, Annales Pharmaceutiques Françaises, 59:239-244
  7. Préat V., Dujardin N
    Topical delivery of nucleic acids in the skin, STP Pharma Sciences, 11:57-68
     [I.F. 0.504]
  8. Préat V., Vanbever R.
    Topical delivery by iontophoresis.
    In: Handbook of Cosmetic Science and Technology, A.O. Barel, M. Paye and I. Maibach ed., Marcel Dekker Inc., 211-219


  1. Baras B., Benoit M.A., Gillard J.
    Influence of various technological parameters on the preparation of spray-dried poly(epsilon-caprolactone) microparticles containing a model antigen
    Journal of Microencapsulation, 17:485-498
  2. Baras B., Benoit M.A., Gillard J.
    Parameters influencing the antigen release from spray-dried poly(DL-lactide) microparticles
    International Journal of Pharmaceutics, 200:133-145
  3. Baras B., Benoit M.A., Poulain-Godefroid O., Schacht A.M., Capron A., Gillard J., Riveau G.
    Vaccine properties of antigens entrapped in microparticles produced by spray-drying technique and using various polyester polymers
    Vaccine, 18:1495-2005
  4. Lombry C., Dujardin N., Préat V.
    Transdermal delivery of macromolecules using skin electroporation
    Pharmaceutical Research, 17:32-37
  5. Regnier V., Tahiri A., André N., Lemaître M., Le Doan T., Préat V.
    Electroporation-mediated delivery of 3'-protected phosphodiester oligodeoxynucleotides to the skin
    Journal of Controlled Release , 67:337-346


  1. Ben-Jebria A., Chen D., Eskew M.L., Vanbever R., Langer R., Edwards D.A.
    Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs
    Pharmaceutical Research, 16:551-561
  2. Baras B., Benoit M.A., Dupré L. Poulain-Godefroy O., Schacht A.M., Capron A., Gillard J., Riveau G.
    Single-dose mucosal immunization with biodegradable microparticles containing a schistosoma mansoni antigen
    Infection and Immunity, 67: 2643-2648
  3. Benoit M.A., Baras B., Gillard J.
    Preparation and characterization of protein-loaded poly(epsilon-caprolactone) microparticles for oral vaccine delivery
    International Journal of Pharmaceutics, 184:73-84
  4. Jadoul A., Bouwstra J., Préat V.
    Effects of iontophoresis and electroporation on the stratum corneum. Review of the biophysical studies, Advanced Drug Delivery Reviews , 35:89-105
  5. Lemoine D., Deschuyteneer M., Hogge F., Préat V.
    Intranasal immunization againts influenza virus using polymeric particles
    Journal of Biomaterials Sciences Polymer Edition , 10:805-825
  6. Prausnitz M.R., Pliquett U., Vanbever R.
    Mechanistic studies of skin electroporation using biophysical methods. In : M.J. Jaroszeski, R. Gilbert and R. Heller(eds) Electrochemotherapy, Electrogenetherapy and transdermal delivery by electroporation-electrically-mediated delivery of molecules to celles, Humana Press pp. 213-245
  7. Vanbever R., Préat V.
    Transdermal drug delivery by skin electroporation in the rat. In : M.J. Jaroszeski, R. Gilbert and R. Heller(eds) Electrochemotherapy, Electrogenetherapy and transdermal delivery by electroporation-electrically-mediated delivery of molecules to celles, Humana Press pp. 457-471
  8. Préat V., Prausnitz M.R.
    Enhanced drug delivery using high-voltage pulses (Preface)
    Advanced Drug Delivery Reviews , 35:1-2
  9. Regnier V., De Morre N., Jadoul A., Préat V.
    Mechanism of a phosphorothioate oligonucleotide delivery by skin electroporation
    International Journal of Pharmaceutics , 184:147-156
  10. Vanbever R.
    Administration transdermique de médicaments par électroporation
    Bulletin et Mémoires de l'Académie royale de Médecine de Belgique , 154:327-333
  11. Vanbever R., Préat V.
    In vivo efficacy and safety of skin electroporation
    Advanced Drug Delivery Reviews , 35:77-88
  12. Vanbever R., Pliquett U.F., Préat V., Weaver J.C.
    Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and trasport properties
    Journal of Controlled Release, 60:35-47
  13. Vanbever R., Mintzes J.D., Wang J., Nice J., Chen D., Batycky R., Langer R., Edwards D.A.
    Formulation and physical characterization of large porous particles for inhalation
    Pharmaceutical Research, 16:1735-1742
  14. Vanbever R., Ben-Jebria A., Mintzes J.D., Langer R., Edwards D.A.,
    Sustained-release of insulin from insoluble inhaled particles, Drug dev. Res,48:178-185
  15. Youan B.B.C., Benoit M.A., Baras B., Gillard J.
    Protein-loaded poly(epsilon-caprolactone) microparticles. I. Optimization of the preparation by (water-in-oil)-in water emulsion solvent evaporatio
    Journal of Microencapsulation, 16:587-599
  16. Youan B.B.C., Benoit M.A., Rollmann B., Riveau G., Gillard J.
    Protein-loaded poly(epsilon-caprolactone) microparticles. II. Muramyl dipeptide for oral controlled release of adjuvant
    Journal of Microencapsulation, 16:601-612
  17. Youan B.B.C., Gillard J., Rollmann B.
    Protein-loaded poly(epsilon-caprolactone) microparticles III. Entrapment of superoxide dismutase by the (water-in-oil)-in water solvent evaporation method
    STP Pharma Sciences, 9:175-181
  18. Zewert T.E., Pliquett U., Vanbever R., Langer R., Weaver J.C.
    Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule
  19. Bioelectrochemistry and Bioenergetics, 49:11-20


  1. Benoit M.A., Baras B., Poulain-Godefroy O., Schacht A.M., Capron A., Gillard J., Riveau G.
    Evaluation of the antibody response after oral immunization by microparticles containing an antigen from schistosoma mansoni.
    In: Biomedical Science and Technology. Recent Developments in the Pharmaceutical and Medical Sciences, Atilla Hincal A. and Süheyla Kas H. Hacettepe University, Ankara, Turkey ed., Plenum Press. New York and London, 137-144
  2. Benoit M.A., Mousset B., Bouillet R., Delloye C., Gillard J.
    Vancomycin-loaded calcium sulfate for the treatment of osteomyelitis - controlled release by a poly(lactide-CO-glycolide) polymer.
    In: Biomedical Science and Technology. Recent Developments in the Pharmaceutical and Medical Sciences, A. Atilla Hincal & H. Süheyla Kas ed., Plenum Press, 189-196
  3. Clarys P., Alewaeters K., Jadoul A., Barel A., Oliveira Manadas R., Préat V.
    In vitro percutaneous penetration through hairless rat skin: influence of temperature, vehicle and penetration enhancers
    European Journal of Pharmaceutics and Biopharmaceutics, 46:279-283
  4. Jadoul A., Lecouturier N., Mesens J., Caers W., Préat V.
    Transdermal alniditan delivery by skin electroporation
    Journal of Controlled Release , 54:265-272
  5. Jadoul A., Tanojo H., Préat V., Bouwstra J.A., Spies F., Boddé H.E.
    Electroperturburation of human stratum corneum fine structure by high voltage pulses: a freeze-fracture electron microscopy and differential thermal analysis study, Journal of Investigative Dermatology Symposium Proceedings, 3:153-158
  6. Lemoine D., Préat V.
    Polymeric nanoparticles as delivery system for influenza virus glycoproteins
    Journal of Controlled Release, 54:15-27
  7. Lemoine D., Francotte M., Préat V.
    Nasal vaccines from fundamental concepts to vaccine development
    STP Pharma Sciences, 8:5-18
  8. Lemoine D., Wauters F., Bouchendhomme S., Préat V.
    Preparation and characterization of alginate microspheres containing a model antigen
    International Journal of Pharmaceutics, 176:9-19
  9. Pliquett U.F., Vanbever R., Préat V., Weaver J.C.
    Local transport regions (LTRs) in human stratum corneum due to long and short 'high voltage' pulses
    Bioelectrochemistry and Bioenergetics , 47:151-161
  10. Préat V.
    Augmentation de la pénétration transdermique des médicaments.
    Bulletin et Mémoires de l'Académie royale de Médecine de Belgique , 153:295-302
  11. Préat V.
    Transdermal delivery of peptides and proteins.
    In: Peptide and Protein Drug Delivery, Frokjaer S., Christrup L. & Krogsgaard-Larsen P. ed., Munksgaard, Copenhagen, 175-182
  12. Regnier V., Préat V.
    Localization of a FITC-labeled phosphorothiote oligodeoxynucleotide in the skin after topical delivery by iontophoresis and electroporation.
    Pharmaceutical Research, 15:1596-1602
  13. Regnier V., Le Doan T., Préat V.
    Parameters controlling topical delivery of oligonucleotides by electroporation
    Journal of Drug Targeting, 5:275-289
  14. Vanbever R., Fouchard D., Jadoul A., De Morre N., Préat V., Marty J.P.
    In vivo noninvasive evaluation of hairless rat skin after high-voltage pulse exposure
    Skin Pharmacology and Applied Skin Physiology, 11:23-34
  15. Vanbever R., Langers G., Montmayeur S., Préat V.
    Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation
    Journal of Controlled Release, 50:225-235
  16. Vanbever R., Leroy M.A., Préat V.
    Transdermal permeation of neutral molecules by skin electroporation
    Journal of Controlled Release, 54:243-250


  1. Benoit M.A., Mousset B., Delloye C., Bouillet R., Gillard J.
    Antibiotic-loaded plaster of Paris implants coated with poly lactide-co-glycolide as a controlled release delivery system for the treatment of bone infections
    International Orthopaedics, 21:403-408
  2. Jadoul A., Préat V.
    Electrically enhanced transdermal delivery of domperidone
    International Journal of Pharmaceutics, 154:229-234
  3. Jadoul A., Regnier V., Doucet J., Durand D., Préat V.
    X-ray scattering analysis of human stratum corneum treated by high voltage pulses
    Pharmaceutical Research, 14:1275-1277
  4. Jadoul A., Regnier V., Doucet J., Durand D., Préat V.
    X-ray scattering analysis of human stratum corneum treated by high-voltage pulses.
    In: Transdermal Administration: a Case Study (iontophoresis), P. Couvreur, D. Duchêne, P. Green and H.E. Junginger ed., Editions de Santé, Paris, 297-301
  5. Préat V., Vanbever R., Jadoul A., Regnier R.
    Electrically enhanced transdermal drug delivery: intophoresis versus electroporation.
    In: Transdermal Administration: a Case Study (Iontophoresis), P. Couvreur, D. Duchêne, P. Green and H.E. Junginger ed., Editions de Santé, Paris, 58-67
  6. Regnier V., Tahiri A., Préat V., Lemaitre M., Le Doan T.
    Topical delivery of 3'end-modified phosphodiester oligonucleotides by electroporation.
    In: Transdermal Administration: a Case Study (iontophoresis), P. Couvreur, D. Duchêne, P. Green and H.E. Junginger ed., Editions de Santé, Paris, 369-373
  7. Vanbever R., Prausnitz M.R., Préat V.
    Macromolecules as novel transdermal transport enhancers for skin electroporation
    Pharmaceutical Research, 14:638-644
  8. Weaver J.C., Vanbever R., Vaughan M.R., Prausnitz M.R.
    Heparin alters transdermal transport associated with electroporation
    Biochemical and Biophysical Research Communications, 234:637-640


  1. Jadoul A., Doucet J., Durand D., Préat V.
    Modifications induced on stratum corneum structure after in vitro iontophoresis: ATR-FTIR and X-ray scattering studies
    Journal of Controlled Release, 42:165-173
  2. Jadoul A., Mesens J., Caers W., de Beukelaar F., Crabbé R., Préat V.
    Transdermal permeation of alniditan by iontophoresis: in vitro optimization and human pharmacokinetic data
    Pharmaceutical Research, 13:1348-1353
  3. Vanbever R., Le Boulengé E., Préat V.
    Transdermal delivery of fentanyl by electroporation I. Influence of electrical factors
    Pharmaceutical Research, 13:559-565
  4. Vanbever R., de Morre N., Préat V.
    Transdermal delivery of fentanyl by electroporation II. Mechanisms involved in drug transport
    Pharmaceutical Research, 13:1360-1366


  1. Dujardin N., Préat V.
    Delivery of DNA to skin by Electroporation. In: Gene Delivery to Mammalian Cells, William C. Heiser ed., Humana Press,
  2. Jadoul A., Hanchard C., Thysman S., Préat V.
    Quantification and localization of fentanyl and TRH delivered by iontophoresis in the skin
    International Journal of Pharmaceutics, 120:221-228
  3. Mousset B., Benoit M-A, Delloye C., Bouillet R., Gillard J.
    Biodegradable implants for potential use in bone infection. An in vitro study of antibiotic-loaded calcium sulphate
    International Orthopaedics 19:157-161
  4. Tasset Ch., Barette N., Thysman S., Ketelslegers J.M., Lemoine D., Préat V.
    Polyisobutylcyanoacrylate nanoparticles as sustained release system for calcitonin
    Journal of Controlled Release, 33:23-30
  5. Thysman S., Jadoul A., Leroy T., Van Neste D., Préat V.
    Laser doppler evaluation of skin reaction in volunteers after histamine iontophoresis
    Journal of Controlled Release, 36:215-219
  6. Thysman S., Van Neste D., Préat V.
    Nonivasive investigation of human skin after in vivo iontophoresis
    Skin Pharmacology, 8:229-236
  7. Vanbever R., Préat V.
    Factors affecting transdermal delivery of metoprolol by electroporation
    Bioelectrochemistry and bioenergetics, 38:223-228