Céline Schoonjans - REMA - Tumor microenvironment involvement in the metabolic reprogramming induced by the PDK inhibitor dichloroacetate

Friday December 18, 2pm

Céline Schoonjans

REMA (Biomedical Magnetic Resonance), LDRI, UCL and FATH (Pharmacologie et Thérapeutique), IREC, UCL

Tumor microenvironment involvement in the metabolic reprogramming induced by the PDK inhibitor dichloroacetate

Only on TEAMS : https://teams.microsoft.com/l/meetup-join/19%3ameeting_MDIxMDNkMjktNWM3Yi00NWMxLTgzYTUtMjQ0YTNlMDlhNDMy%40thread.v2/0?context=%7b%22Tid%22%3a%227ab090d4-fa2e-4ecf-bc7c-4127b4d582ec%22%2c%22Oid%22%3a%2200b6c117-953b-47f8-8a63-cfcba01b1a60%22%2c%22IsBroadcastMeeting%22%3atrue%7d

Supervisors : Bernard Gallez (promotor) and Olivier Feron (co-promotor)

Related publications :

• Schoonjans, C. A., Joudiou, N., Brusa, D., Corbet, C., Feron, O., & Gallez, B. (2020). Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate. Cancer Letters, 470, 18-28.
• Schoonjans, C. A., Mathieu, B., Joudiou, N., Zampieri, L. X., Brusa, D., Sonveaux, P., ... & Gallez, B. (2020). Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1. Journal of clinical medicine, 9(10), 3308.
• Schoonjans, C. A., & Gallez, B. (2020). Metabolic Plasticity of Tumor Cells: How They Do Adapt to Food Deprivation. In Tumor Microenvironment (pp. 109-123). Springer, Cham.

Info: bernard.gallez@uclouvain.be