November 12, 2018
Former Medicinal Chemistry Director at Ogeda (Gosselie, Belgium)
Scientific collaborator at CMFA, LDRI (UCLouvain)
The Discovery of Fezolinetant (ESN364): A Novel NK3 Antagonist for Treatment of Sex-Hormone Disorders & Vasomotor Symptoms (Hot Flashes)
Related references:
- Hoveyda et al. Discovery and optimization of novel antagonists to the human neurokinin-3 receptor for the treatment of sex-hormone disorders. J Med Chem. 2015 Apr 9;58(7):3060-82. doi: 10.1021/jm5017413. Epub 2015 Mar 18.
- Fraser et al. The NK3 Receptor Antagonist ESN364 Suppresses Sex Hormones in Men and Women. J Clin Endocrinol Metab. 2016 Feb;101(2):417-26.
Info : Raphaël Frédérick