Pauline Bottemanne, BPBL LDRI, Endocannabinoids and 25-hydroxycholesterol as modulators of inflammation

Bruxelles Woluwe

September 14, 2020

Supervisor: Prof. Giulio G. Muccioli – Co-supervisor: Dr. Mireille Alhouayek

Related references:

25-hydroxycholesterol metabolism is altered by lung inflammation and its local administration modulates lung inflammation. Bottemanne P, Paquot A, Ameraoui H, Guillemot-Legris O, Alhouayek M, Muccioli GG, submitted

N-acylethanolamine-hydrolyzing acid amidase inhibition, but not fatty acid amide hydrolase inhibition, prevents the development of experimental autoimmune encephalomyelitis in mice. Bottemanne P, Guillemot-Legris O, Paquot A, Masquelier J, Malamas M, Makriyannis A, Alhouayek M, Muccioli GG, in revision

The α/β-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids. Bottemanne P, Paquot A, Ameraoui H, Alhouayek M, Muccioli GG. FASEB J. 2019;33(6):7635-7646.

N-acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities. Bottemanne P, Muccioli GG, Alhouayek M. Drug Discov Today. 2018;23(8):1520-1529.