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"Despite the « lockdown », I’m glad to have been able to present my PhD thesis in a “videoconference style”, surrounded (1.5 meters away) by my family and a few friends after all."
May 2020
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Alice Ameryckx (Medicinal Chemistry/Cellular and Molecular Pharmacology, LDRI)
Design, synthesis and evaluation of D-alanyl-D-Alanine ligase inhibitors: an attractive target for the development of antimicrobial agents
Promoters: Pr. Raphaël Frédérick, Pr. Françoise Van Bambeke
Related Publications :
- Ameryckx, A.; Thabault, L.; Pochet, L.; Leimanis, S.; Poupaert, J. H.; Wouters, J.; Joris, B.; Van Bambeke, F.; Frederick, R., 1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio. Eur. J. Med. Chem. 2018, 159, 324-338.
- Ameryckx A.; Pochet, L.; Wang G.; Yildiz E.; Es Saadi B.; Wouters J.; Van Bambeke, F.; Frederick, R.; Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio. Eur. J. Med. Chem. 2020, accepted.
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May 2020
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Natalija Tatic (Advanced Drug Delivery and Biomaterials, LDRI)
Modulation of macrophage phenotype for spinal cord injury repair
Promoters: Prof. Lisa White (University of Nottingham) and Anne des Rieux
Related publication:
- Tatic, N., Rose, F., des Rieux, A. & White, L. J. Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells. Sci Rep 9, 14015, doi:10.1038/s41598-019-50367-x (2019).
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"Thanks to a defense via Teams, I was happy that my family and my colleagues in Vietnam could participate"
June 2020
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Tiep Khac Nguyen (Cellular and Molecular Pharmacology, LDRI)
Antibiotic resistance in Vietnam in relation with persistent forms of infection
Promoter: F. Van Bambeke
- Nguyen TK et al. Antibiotic resistance, biofilm formation, and intracellular survival as possible determinants of persistent or recurrent infections by Staphylococcus aureus in a Vietnamese tertiary hospital. Focus on bacterial response to moxifloxacin. Microbial Drug Resistance. 2019 doi: 10.1089/mdr.2019.0282
- Nguyen TK et al. Contribution of antibiotic persistence and resistance towards failure to eradicate intracellular infection by clinical isolates of Staphylococcus aureus. Submitted.
- Peyrusson F, Varet H, Nguyen TK et al. Intracellular Staphylococcus aureus persisters upon antibiotic exposure. Nat Commun . 2020 May 4;11(1):2200.
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"My virtual PhD defense was an amazing journey that would be a special memory in my life. Thank you to all who witnessed my defense! "
April 2020
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Yining Xu (Advanced Drug Delivery and Biomaterials, LDRI)
Peptide-loaded nanoparticle oral delivery strategies towards diabetes treatment
Promoter: Ana Beloqui
Related papers
- Xu Y., Shrestha N., Préat V., Beloqui A. Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems. Journal of Controlled Release (2020). In press
- Xu Y., van Hul M., Suriano F., Préat V., Cani P.D., Beloqui A. A novel strategy for oral peptide delivery in incretin-based diabetes treatment. Gut 69 (2020) 911-919.
- Xu Y., Carradori D., Alhouayek M., Muccioli G.G., Cani P.D., Préat V., Beloqui A. Size effect on lipid nanocapsules-mediated GLP-1 secretion from enteroendocrine L cells. Molecular Pharmaceutics 15 (2018) 108-115.
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