4 virtual PhD defenses for 4 real new doctors !!

Bruxelles Woluwe

"Despite the « lockdown », I’m glad to have been able to present my PhD thesis in a “videoconference style”, surrounded (1.5 meters away) by my family and a few friends after all."

May 2020

Alice Ameryckx (Medicinal Chemistry/Cellular and Molecular Pharmacology, LDRI)

Design, synthesis and evaluation of D-alanyl-D-Alanine ligase inhibitors: an attractive target for the development of antimicrobial agents

Promoters: Pr. Raphaël Frédérick, Pr. Françoise Van Bambeke

Related Publications :

  • Ameryckx, A.; Thabault, L.; Pochet, L.; Leimanis, S.; Poupaert, J. H.; Wouters, J.; Joris, B.; Van Bambeke, F.; Frederick, R., 1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio. Eur. J. Med. Chem. 2018, 159, 324-338.
  • Ameryckx A.; Pochet, L.; Wang G.; Yildiz E.; Es Saadi B.; Wouters J.; Van Bambeke, F.; Frederick, R.; Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio. Eur. J. Med. Chem. 2020, accepted.

May 2020

Natalija Tatic (Advanced Drug Delivery and Biomaterials, LDRI)

Modulation of macrophage phenotype for spinal cord injury repair

Promoters: Prof. Lisa White (University of Nottingham) and Anne des Rieux

Related publication:

  • Tatic, N., Rose, F., des Rieux, A. & White, L. J. Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells. Sci Rep 9, 14015, doi:10.1038/s41598-019-50367-x (2019).

"Thanks to a defense via Teams, I was happy that my family and my colleagues in Vietnam could participate"

June 2020

Tiep Khac Nguyen (Cellular and Molecular Pharmacology, LDRI)

Antibiotic resistance in Vietnam in relation with persistent forms of infection

Promoter: F. Van Bambeke

  • Nguyen TK et al. Antibiotic resistance, biofilm formation, and intracellular survival as possible determinants of persistent or recurrent infections by Staphylococcus aureus in a Vietnamese tertiary hospital. Focus on bacterial response to moxifloxacin. Microbial Drug Resistance. 2019 doi: 10.1089/mdr.2019.0282
  • Nguyen TK et al. Contribution of antibiotic persistence and resistance towards failure to eradicate intracellular infection by clinical isolates of Staphylococcus aureus. Submitted.
  • Peyrusson F, Varet H, Nguyen TK et al. Intracellular Staphylococcus aureus persisters upon antibiotic exposure. Nat Commun . 2020 May 4;11(1):2200.

"My virtual PhD defense was an amazing journey that would be a special memory in my life. Thank you to all who witnessed my defense! "

April 2020

Yining Xu (Advanced Drug Delivery and Biomaterials, LDRI)

Peptide-loaded nanoparticle oral delivery strategies towards diabetes treatment

Promoter: Ana Beloqui

Related papers

  • Xu Y., Shrestha N., Préat V., Beloqui A. Overcoming the intestinal barrier: A look into targeting approaches for improved oral drug delivery systems. Journal of Controlled Release (2020). In press
  • Xu Y., van Hul M., Suriano F., Préat V., Cani P.D., Beloqui A. A novel strategy for oral peptide delivery in incretin-based diabetes treatment. Gut 69 (2020) 911-919.
  • Xu Y., Carradori D., Alhouayek M., Muccioli G.G., Cani P.D., Préat V., Beloqui A. Size effect on lipid nanocapsules-mediated GLP-1 secretion from enteroendocrine L cells. Molecular Pharmaceutics 15 (2018) 108-115.


Published on June 23, 2020