Annual meeting of the Belgian Nutrition
Sarah Pötgens (MNUT research group/LDRI) won the young researcher oral presentation competition at the Belgian Nutrition Society annual meeting on May 3. In her presentation, she showed results of her PhD project which aims to unravel the pathways underlying the host-microbiota crosstalk in cancer cachexia by using, among others, NMR metabolomics and gut microbiota sequencing. These analyses reveal alterations in gut microbiota composition, as well as associated cecal and liver metabolites in a preclinical model of cachexia. The project is still ongoing and will now be oriented by these results to interrogate the role of specific microbial-host pathways in this pathological context. Indeed, the exploitation of such pathways may represent a druggable approach to harvest the therapeutic potential of the gut microbiota in cancer cachexia.
https://uclouvain.be/en/research-institutes/ldri/in-the-context-of-cancer-cachexia.html