Bruxelles Woluwe


  1. Phenolic profiling in the pulp and peel of nine plantain cultivars (Musa sp.).
    Passo Tsamo C.V., Herent M.F., Tomekpe K., Happi Emaga T., Quetin-Leclercq J., Rogez H., Larondelle Y., Andre C.
    Food Chem. 2015 Jan 15;167:197-204.
  2. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota .
    Geurts L., Everard A., Van Hul M., Essaghir A., Duparc T., Matamoros S., Plovier H., Castel J., Denis R.G., Bergiers M., Druart C., Alhouayek M., Delzenne N.M., Muccioli G.G., Demoulin J.B., Luquet S., Cani P.D.
    Nat. Commun., 6, 6495.
  3. Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms .
    Vandevelde N.M., Tulkens P.M., Muccioli G.G., Van Bambeke F.
    J. Antimicrob. Chemother., 70(6), 1713-1726


  1. Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status.
    Everard A., Geurts L., Caesar R., Van Hul M., Matamoros S., Duparc T., Denis R.G., Cochez P., Pierard F., Castel J., Bindels L.B., Plovier H., Robine S., Muccioli G.G., Renauld J.C., Dumoutier L., Delzenne N.M., Luquet S., Bäckhed F., Cani P.D.
    Nat Commun., 5, 5648
  2. Synthesis, half-wave potentials and antiproliferative activity of 1-aryl-substituted aminoisoquinolinequinones 
    Ibacache J.A., Delgado V., Benites J., Theoduloz C., Arancibia V., Muccioli G.G., Valderrama J.A.
    Molecules, 19(1), 726-739
  3. Chemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin
    Kpoviessi S., Bero J., Agbani P., Gbaguidi F., Kpadonou-Kpoviessi B., Sinsin B., Accrombessi G., Frédérich M., Moudachirou M., Quetin-Leclercq J.
    J. Ethnopharmacol., 151(1), 652-659


  1. Effect of Drug-Targeting Nebulization on Lung Delivery
    Reychler G, Aubriot AS, Masquelier J, Muccioli GG, Liistro G
    Arch Bronconeumol. 2013 Dec 28. pii: S0300-2896(13)00356-6
  2. Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6
    Alhouayek M, Masquelier J, Cani PD, Lambert DM, Muccioli GG
    Proc Natl Acad Sci U S A. 2013; 110(43):17558-63.
  3. Eco-friendly synthesis and antiproliferative evaluation of some oxygen substituted diaryl ketones
    Arenas P, Peña A, Ríos D, Benites J, Muccioli GG, Calderon PB, Valderrama JA
    Molecules. 2013;18(8):9818-32
  4. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
    Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
    Proc Natl Acad Sci U S A. 2013 May 13.
  5. Fast method for the simultaneous quantification of toxic polyphenols applied to the selection of genotypes of yam bean (Pachyrhizus sp.) seeds
    Lautié E, Rozet E, Hubert P, Vandelaer N, Billard F, Zum Felde T, Grüneberg WJ, Quetin-Leclercq J.
    Talanta. 2013 Dec 15;117:94-101.
  6. Mass spectrometric characterization of organosulfates related to secondary organic aerosol from isoprene
    Safi Shalamzari M, Ryabtsova O, Kahnt A, Vermeylen R, Hérent MF, Quetin-Leclercq J, Van der Veken P, Maenhaut W, Claeys M.
    Rapid Commun Mass Spectrom. 2013 Apr 15;27(7):784-94.
  7. Piceatannol, a potent bioactive stilbene, as major phenolic component in Rhodomyrtus tomentosa
    Lai TN, Herent MF, Quetin-Leclercq J, Nguyen TB, Rogez H, Larondelle Y, André CM.
    Food Chem. 2013 Jun 1;138(2-3):1421-30
  8. In vivo antimalarial activity of Keetia leucantha twigs extracts and in vitro antiplasmodial effect of their constituents
    Bero J, Hérent MF, Schmeda-Hirschmann G, Frédérich M, Quetin-Leclercq J.
    J Ethnopharmacol. 2013 Aug 26;149(1):176-83. doi:
  9. Fast microwave-assisted extraction of rotenone for its quantification in seeds of yam bean (Pachyrhizus sp.)
    Lautié E, Rasse C, Rozet E, Mourgues C, Vanhelleputte JP, Quetin-Leclercq J.
    J Sep Sci. 2013 Feb;36(4):758-63.
  10. Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase
    Bero J, Beaufay C, Hannaert V, Hérent MF, Michels PA, Quetin-Leclercq
    J. Phytomedicine. 2013 Feb 15;20(3-4):270-4.
  11. Development and validation of an UHPLC-LTQ-Orbitrap MS method for non-anthocyanin flavonoids quantification in Euterpe oleracea juice
    Dias AL, Rozet E, Larondelle Y, Hubert P, Rogez H, Quetin-Leclercq J.
    Anal Bioanal Chem. 2013 Nov;405(28):9235-49
  12. Degradation of rotenone in yam bean seeds ( Pachyrhizus sp.) through food processing 
    Catteau L, Lautié E, Koné O, Coppée M, Hell K, Pomalegni CB, Quetin-Leclercq J.
    J Agric Food Chem. 2013 Nov 20;61(46):11173-9
  13. Chronic endocannabinoid system stimulation induces muscle macrophage and lipid accumulation in type 2 diabetic mice independently of metabolic endotoxaemia
    Geurts L, Muccioli GG, Delzenne NM, Cani PD.
    PLoS One. 2013;8(2):e55963.


  1. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action.
    L. Hamtiaux, J. Masquelier, G. G. Muccioli, C. Bouzin, O. Feron, B. Gallez, D.M Lambert.
    BMC Cancer, 2012, 12(92): 1-14
  2. Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo
    B. Bosier, G. G. Muccioli, B. Mertens, S. Sarre, Y. Michotte, D. M. Lambert, E. Hermans Neuropharmacology, 2012, 62: 2327- 2335
  3. Gut microbiota-derived propionate reduces cancer cell proliferation in the liver
    L.B. Bindels, P. Porporato, E.M. Dewulf, J. Verrax, A.M. Neyrinck, J.C. Martin, K.P. Scott, P. Buc Calderon, O. Feron, G.G. Muccioli, P. Sonveaux, P.D. Cani, N.M. Delzenne
    British Journal of Cancer, 2012: 1–8
  4. Synthesis and Pharmacological Evaluation of 2,4-Dinitroaryldithiocarbamate Derivatives as Novel Monoacylglycerol Lipase Inhibitors
    C. N. Kapanda, J. Masquelier, G. Labar, G. G. Muccioli, J. H. Poupaert, D. M. Lambert
    Journal of Medicinal Chemistry, 2012, 55, 5774−5783
  5. Funcionalized phosphonated half-cage molecules as ligands for metal complexes
    E. Villemin, M.-F. Hérent, J. Marchand-Brynaert.
    European Journal of Organic Chemistry, 31, 6165-6178, 2012
  6. Anti-inflammatory effects of pomegranate (Punica granatum L.) husk ellagitannins in Caco-2 cells, an in vitro model of human intestine.
    S. Hollebeeck, J. Winand, M.-F. Herent, A. During, J. Leclercq, Y. Larondelle, Y.-J. Schneider.
    Food & Function, 3(8), 875-885, 2012.
  7. Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum 
    D.C.Ganfon H. , Bero J., Tchinda A.T., Gbaguidi F., Gbenou J., Moudachirou M., Frédérich M., Quetin-Leclercq J.
    J. Ethnopharmacol., 141 (2012) : 411– 417
  8. Quantification of rotenone in seeds of different species of yam bean (Pachyrhizus sp.) by a SPE HPLC–UV method.
    Lautié E., Rozet E., Hubert P., Quetin Leclercq J.
    Food Chemistry 131(4) (2012): 1531-1538
  9. Characterization of an endophytic whorl-forming Streptomyces from Catharanthus roseus stems producing polyene macrolide antibiotic.
    Rakotoniriana E.F., Chataigné, G., Raoelison G., Rabemanantsoa C., Munaut F., El Jaziri M., Urveg-Ratsimamanga S., Marchand-Brynaert J., Corbisier A.-M., Declerck S., Quetin-Leclercq J.
    Can. J. Microbiol. 58 (2012) 617-627
  10. A rapid validated UHPLC–PDA method for anthocyanins quantification from Euterpe oleracea fruits.
    Dias A.L.S., Rozet E., Chataigné G., Oliveira A.C., Rabelo C.A.S., Hubert Ph., Rogez H., Quetin-Leclercq J.
    Journal of Chromatography B, 907 (2012) 108– 116


  1. SAR and LC/MS Studies of β-Lactamic Inhibitors of Human Fatty Acid Amide Hydrolase (hFAAH): Evidence of a Nonhydrolytic Process 
    M. Feledziak, G. G. Muccioli, D. M. Lambert, J. Marchand-Brynaert
    Journal of Medicinal Chemistry, 2011, 54: 6812–6823
  2. Dual Inhibition of α/β-Hydrolase Domain 6 and Fatty Acid Amide Hydrolase Increases Endocannabinoid Levels in Neurons
    W.R. Marrs, E. A. Horne, S. Ortega-Gutierrez, J. A.Cisneros, C. Xu, Y. Hsing Lin, G. G. Muccioli, M. L. Lopez-Rodriguez, N.Stella Journal of Biological Chemistry, 2011, 286(33): 28723-28728
  3. Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue
    L. Geurts, V. Lazarevic, M. Derrien, A. Everard, M. Van Roye, C. Knauf, P. Valet, M. Girard, G.G. Muccioli, P. François, W. M. deVos, J. Schrenzel, N.M. Delzenne, P.D. Cani. Frontiers in Microbiology, 2011, 2(149): 1-17
  4. Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation
    M. Alhouayek, D. M. Lambert, N. M. Delzenne, P. D. Cani, G. G. Muccioli. The FASEB Journal, 2011, 25: 2711-2721
  5. Hepatic n-3 Polyunsaturated Fatty Acid Depletion Promotes Steatosis and Insulin Resistance in Mice: Genomic Analysis of Cellular Targets.
    B. D. Pachikian, A. Essaghir, J.-B. Demoulin, A. M. Neyrinck, E. Catry, F. C. De Backer, N. Dejeans, E. M. Dewul1, F. M. Sohet, L. Portois, L. Deldicque, O. Molendi-Coste, I. A. Leclercq, M. Francaux, Y.A. Carpentier, F. Foufelle, G. G. Muccioli, P. D. Cani, N. M. Delzenne. PlosOne, 2011, 6(8) e23365: 1-13
  6. Increasing Antiproliferative Properties of Endocannabinoids in N1E-115 Neuroblastoma Cells through Inhibition of Their Metabolism.
    L. Hamtiaux, L. Hansoulle, N. Dauguet, G. G. Muccioli, B. Gallez, D. M. Lambert. PlosOne, 2011, 6(10) e26823: 1-14
  7. Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice.
    C. Thabuis, F. Destaillats, D. M. Lambert, G. G. Muccioli , M. Maillot, T. Harach , D. Tissot-Favre , J.-C.Martin.
    Journal of Lipid Research Volume, 2011, 52: 1373-1382
  8. Novel phosphonated bicyclic frameworks from Diels–Alder reaction as chelating agents of di- and trivalent metal cations.
    E. Villemin , B. Elias , R. Robiette , K. Robeyns , M.-F. Herent , J.-L. Habib-Jiwan, J. Marchand-Brynaert
    Tetrahedron Letters, 52, 5140-5144, 2011
  9. In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract.
    J. Bero, V. Hannaert, G. Chataigné, M.-F. Hérent, J. Quetin-Leclercq.
    Journal of Ethnopharmacology, 137, 998-1002, 2011.
  10. Identification by LC-ESI-MS of Flavonoids Responsible for the Antioxidant Properties of Mallotus Species from Vietnam.
    V N.T. Hong, C. Rivière, Q. T. Hong, G.Chataigné, N.N. Hoai, B. Dejaegher, C. Tistaert, T. N.T. Kim, K. P. Van, Y. Vander Heyden, M. C. Van and J.Quetin-Leclercq.
    Natural Products Communications 6(6) (2011): 813-818


  1. The serine hydrolase ABHD6 controls 2-AG the accumulation and efficacy at cannabinoid receptors
    W. Marrs, J. Blankman, E. Horne, A. Thomazeau, Y.H. Lin, J. Coy, A. Bodor, G.G. Muccioli, S. Shu-Jung Hu, G. Woodruff, S. Fung, M. Lafourcade, J. Alexander, J. Long, W. Li, C. Xu, T.Möller, K. Mackie, O. Manzoni, B. Cravatt, N. Stella
    Nature Neuroscience, 2010,13(8):951-7
  2. Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
    Collard F., Stroobant V., Lamosa P., Kapanda C.N., Lambert D.M., Muccioli G.G., Poupaert J.H., Opperdoes F., Van Schaftingen E.
    Journal of Biological Chemistry, 2010, 285, 29826-29833.
  3. The endocannabinoid system links gut microbiota to adipogenesis. G.G. Muccioli, D. Naslain, F. Bäckhed, C. Reigstad, D.M Lambert, N.M. Delzenne, P.D. Cani. Molecular Systems Biology, 2010, 6(392): 1-15
  4. Photodegradation of flupentixol in aqueous solution under irradiation at 254 nm : Identification of the photoproducts generated. A. Maquille, S. Salembier, M.-F. Hérent, J.-L. Habib Jiwan, Journal of Photochemistry and Photobiology A : Chemistry, 214, 224-229, 2010.
  5. Mallotus species from Vietnamese moutainous areas: phytochemistry and pharmacological activities C. Rivière, V. Nguyen Thi Hong, Q. Tran Hong, G. Chataigné, N. Nguyen Hoai, B. Dejaegher, C. Tistaert, T. Nguyen Thi Kim, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq. Phytochemistry Reviews (2010) 9: 217-25


  1. Polyphenols isolated from antiradical extracts of Mallotus metcalfianus
    Rivière C. , V. Nguyen V., L. Pieters L., B. Dejargher B., Y. Vander Heyden Y., M. Chau Van M., J. Quetin-Leclercq J.
    Phytochemistry, 70, 91-99
  2. Genetic Manipulation of Palmitoylethanolamide Production and Inactivation in Saccharomyces cerevisiae.
    Muccioli G.G., A. Sia A., P. Muchowski P., N. Stella N.
    PlosOne, 4(6) e5942: 1-10