Applied research contracts - Archive

> SAS Partnership (2012-2014)

▪ FINANCING: SAS
▪ GRANT HOLDER: C. Legrand
The SAS software is one of the most used statistical software in the world. Since several years, there exist a partenariat between SAS and Institut de Statistique, Biostatistique et Sciences Actuarielles (ISBA) through which courses of programming in SAS and data mining techniques are organized. These courses are open to all master students as well as to PhD students and to all researchers of the UCL. Within the context of this partenariat, SAS also support (financially and logistically) the organisation of short courses within ISBA.

> Statistical monitoring applied to research trials (2011-2013)

▪ FINANCING: Biowin (pôle de compétitivité region wallonne)
▪ GRANT HOLDER: C. Legrand
The objective is to develop and validate a software for central statistical monitoring of clinical trial data quality. This software will ne primarily based on a large number of statistical tests as well as on techniques from data mining and artificial intelligence. This tool will allow to detect abnormalities in data, resulting from errors, negligence, or fraud.

> External Statistician of the Independent Data Monitoring Committee for GSK-Biologicals Study “MAGRIT trial MAGE-A3 as Adjuvant Non-Small Cell LunG CanceR ImmunoTherapy” (2009-2013)

▪ FINANCING: GlaxoSmithKline Biologicals
▪ GRANT HOLDER: C. Legrand
GlaxoSmithKline Biologicals is currently conducting a large phase III clinical trial in lung cancer aiming to investigate the effect of an antigen-specific cancer immunotherapeutic as adjuvent treatment for patients with resectable non-small cell lung cancer. This clinical trial will enroll more than 2000 patients and to ensure the safety of these patients, this trial is regularly monitored by an independent committee of experts (Independent Data Monitoring Committee). The role of this IDMC is to review, at regular time interval, all the data available to ensure that further continuation of the trial is ethical and eventually to make recommendations with regards to the conduct of the trial. This IDMC is composed of 5 experts; 4 medical doctors and 1 statistician. Catherine Legrand, Institut de Statistique, Biostatistique et Sciences Actuarielles (ISBA), acts as independent statistician in this IDMC.

> SAS Partnership (2008-2012)

▪ FINANCING: SAS
▪ GRANT HOLDER: C. Legrand
The SAS software is one of the most used statistical software in the world. Since several years, there exist a partenariat between SAS and Institut de Statistique, Biostatistique et Sciences Actuarielles (ISBA) through which courses of programming in SAS and data mining techniques are organized. These courses are open to all master students as well as to PhD students and to all researchers of the UCL. Within the context of this partenariat, SAS also support (financially and logistically) the organisation of short courses within ISBA.