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- Arthur Colson
Arthur Colson was graduated as a medical doctor at the université catholique de Louvain (UCLouvain), in Brussels (Belgium) two years ago. During his studies, he was always interested in research and learning the laboratory techniques in parallel of his medical training. Thereby, he discovered many areas of research such as immunology, oncology, hepatology and obstetrics. His last project gave me the opportunity to be enrolled in the PhD program of the university in the laboratory of Prof. F. Debiève (Experimental and Clinical Research Institute, IREC). At the same time, he was successfully accepted in the gynecology/obstetrics residency in the Saint-Luc university hospital (Brussels). His research project is focused on placental development and its influence on fetal growth. The experimental setup includes both manipulations on primary trophoblasts and human samples.
Colson, Arthur ; Depoix, Christophe ; Lambert, Isaline ; Leducq, Camille ; Bedin, Marie ; De Beukelaer, Michèle ; Gatto, Laurent ; Loriot, Axelle ; Peers de Nieuwburgh, Maureen ; Bouhna, Khadija ; Baldin, Paméla ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Specific hypoxia-inducible factor-2 (HIF-2α) inhibitor PT2385 mitigates placental dysfunction in vitro and in a rat model of preeclampsia (RUPP). In: Hypertension., Vol. 80, no. 5, p. 1011-1023 (2023). doi:10.1161/HYPERTENSIONAHA.122.20739.
Schwartz, David A ; Avvad-Portari, Elyzabeth ; Babál, Pavel ; Baldewijns, Marcella ; Blomberg, Marie ; Bouachba, Amine ; Camacho, Jessica ; Collardeau-Frachon, Sophie ; Colson, Arthur ; Dehaene, Isabelle ; Ferreres, Joan Carles ; Fitzgerald, Brendan ; Garrido-Pontnou, Marta ; Gergis, Hazem ; Hargitai, Beata ; Helguera-Repetto, A Cecilia ; Holmström, Sandra ; Irles, Claudine Liliane ; Leijonhfvud, Åsa ; Libbrecht, Sasha ; Marton, Tamás ; McEntagart, Noel ; Molina, James T ; Morotti, Raffaella ; Nadal, Alfons ; Navarro, Alexandra ; Nelander, Maria ; Oviedo, Angelica ; Otani, Andre Ricardo Oyamada ; Papadogiannakis, Nikos ; Petersen, Astrid C ; Roberts, Drucilla J ; Saad, Ali G ; Sand, Anna ; Schoenmakers, Sam ; Sehn, Jennifer K ; Simpson, Preston R ; Thomas, Kristen ; Valdespino-Vázquez, M Yolotzin ; van der Meeren, Lotte E ; Van Dorpe, Jo ; Verdijk, Robert M ; Watkins, Jaclyn C ; Zaigham, Mehreen. Placental Tissue Destruction and Insufficiency From COVID-19 Causes Stillbirth and Neonatal Death From Hypoxic-Ischemic Injury.. In: Archives of pathology & laboratory medicine, Vol. 146, no.6, p. 660-676 (2022). doi:10.5858/arpa.2022-0029-SA.
Colson, Arthur ; Sonveaux, Pierre ; Debiève, Frédéric ; Sferruzzi-Perri, Amanda N. Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction. In: Human Reproduction Update, Vol. 27, no. 3, p. 531-569 (2021). doi:10.1093/humupd/dmaa053.
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. COVID-19 during Pregnancy: Clinical and In Vitro Evidence against Placenta Infection at Term by SARS-CoV-2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Danhaive, Olivier ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Clinical and in Vitro Evidence against Placenta Infection at Term by Severe Acute Respiratory Syndrome Coronavirus 2.. In: The American journal of pathology, Vol. 191, no. 9, p. 1610-1623 (2021). doi:10.1016/j.ajpath.2021.05.009.
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Debiève, Frédéric. Isolation of Primary Cytotrophoblasts From Human Placenta at Term. In: BIO-PROTOCOL, Vol. 11, no.19, p. 1 (2021). doi:10.21769/bioprotoc.4185.
Depoix, Christophe ; Colson, Arthur ; Mhallem Gziri, Mina ; Hubinont, Corinne ; Debiève, Frédéric. Effects of chemotherapy on placental development and function using in vitro culture of human primary cytotrophoblasts.. In: Investigational new drugs, Vol. 38, no. 3, p. 547-557 (2020). doi:10.1007/s10637-019-00800-9.
Colson, Arthur ; Depoix, Christophe ; Baldin, Paméla ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Hypoxia-inducible factor 2 alpha impairs human cytotrophoblast syncytialization: new insights in placental dysfunction and fetal growth restriction. In: The FASEB Journal, Vol. 34, no. 11, p. 15222-15235 (2020). doi:10.1096/fj.202001681R.
Depoix, Christophe ; Colson, Arthur ; Hubinont, Corinne ; Debieve, Frédéric. Impaired vascular endothelial growth factor expression and secretion during in vitro differentiation of human primary term cytotrophoblasts.. In: Angiogenesis, Vol. 23, no. 2, p. 221-230 (2020). doi:10.1007/s10456-019-09702-z.
Colson, Arthur ; Brinkley, Anita ; Braconnier, Philippe ; Ammor, Nadia ; Burnier, Michel ; Pruijm, Menno. Impact of salt reduction in meals consumed during hemodialysis sessions on interdialytic weight gain and hemodynamic stability.. In: Hemodialysis International, Vol. 22, no.4, p. 501-506 (2018). doi:10.1111/hdi.12655.
Ciccarelli, Olga ; Colson, Arthur ; De Saeger, Christine ; Reding, Raymond ; Sempoux, Christine ; Leclercq, Isabelle ; Starkel, Peter. Tumoral response and tumoral phenotypic changes in a rat model of diethylnitrosamine-induced hepatocellular carcinoma after salirasib and sorafenib administration.. In: OncoTargets and Therapy, Vol. 11, p. 7143-7153 (2018). doi:10.2147/OTT.S176903.
Colson, Arthur ; Depoix, Christophe ; Baldin, Paméla ; Mhallem Gziri, Mina ; Steenhaut, Patricia ; van der Monde, Julie ; Van Grambezen, Aurianne ; Bernard, Pierre ; Danhaive, Olivier ; Hubinont, Corinne ; Debieve, Frédéric. Assessment of SARS-CoV-2 vertical transmission: analysis of the 31 placentas from the PREG-COV study. 27th European Congress of Obstetrics and Gynaecology (EBCOG) (Athens, du 02/09/2021 au 04/09/2021).
Colson, Arthur ; Depoix, Christophe ; Dessilly, Géraldine ; Baldin, Paméla ; Hubinont, Corinne ; Danhaive, Olivier ; Sonveaux, Pierre ; Debieve, Frédéric. Risk of COVID-19 maternofetal transmission at term: new evidence against placental infection by SARS-CoV-2. IFPA Annual Meeting 2021 (Virtual, du 30/08/2021 au 02/09/2021).
Colson, Arthur ; Lambert, Isaline ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debieve, Frédéric. Use of the Hypoxia-Inducible Factor (HIF)-2α Inhibitor PT2385 in Placental Dysfunction: New Intervention Addressing Fetal Growth Restriction and Preeclampsia. 68th annual meeting of the Society for Reproductive Investigation (Boston, du 06/07/2021 au 09/07/2021).
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Hypoxia-Inducible Factor 2α (HIF-2α) Impairs Placental Development in Fetal Growth Restriction (FGR). 22th annual meeting of the Society for Reproductive Investigation (Vancouver, du 10/03/2020 au 14/03/2020).
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Debiève, Frédéric. Hypoxia-Inducible Factor 2 (EPAS1) Decreases Syncytialization in Primary Villous Cytotrophoblasts. 21th annual meeting of the Society for Reproductive Investigation (Paris, du 12/03/2019 au 16/03/2019).
Colson, Arthur ; Depoix, Christophe ; Hubinont, Corinne ; Sonveaux, Pierre ; Debiève, Frédéric. Oxygen-resistant Hypoxia-Inducible Factor-2a (EPAS1) Mutant Inhibits Forskolin-induced Differentiation of Choriocarcinoma Cell Line BeWo. CTR Annual Conference (Cambridge, du 08/07/2019 au 09/07/2019).
Colson, Arthur. Targeting the hypoxia-inducible factor 2α in placental dysfunction : towards new treatments for preeclampsia and fetal growth restriction, prom. : Debiève, Frédéric ; Sonveaux, Pierre, 23/11/2023.