Pursuit of Perfection? On Brain Organoids as Models

Bruxelles Woluwe

De Maxence Gaillard & Mylène Botbol-Baum

Article paru dans la revue AJOB Neuroscience (volume 13 de 2022)

In this issue, Sawai and colleagues draw a map of the emerging field of brain organoid ethics. The constitution of this field is dependent on the concept of a brain organoid that would be considered as deserving ethical consideration. Brain organoid research in itself is a broad field and many different entities could qualify as brain organoids, from the early self-organizing neural cell cultures (Lancaster) to organoids modeling this or that part of the brain, until complex physiological systems such as assembloids (Birey), and we might also discuss problems raised by brain organoids made from human material, human-animal chimeras, and so on. While the target article reviews the different questions that might be raised for different kinds of entities, the diversity of entities that we group conveniently under the label brain organoid should not be underestimated...

Publié le 25 mars 2022