The objective of our research is to use drug delivery systems and biomaterials as a mean to improve therapeutic outcomes of drugs. We develop drug delivery systems going from nano-scale, through micro-scale up to macro-scale (Figure 1A).
Our different research applications can be gathered into two research themes (Figure 1B):
Figure 1: A. Drug delivery systems and biomaterials developed/used by the ADDB group; B. Biomedical applications
1. Nanomedicines:
a. Cancer: this theme focuses on targeted theranostic nanoparticles loaded with anticancer drugs or siRNA, adjuvanted recombinant antigens and gene vaccines.
b. Mucosal delivery routes: this theme includes the research on oral delivery using nanomedicines, cutaneous delivery and pulmonary delivery.
c. CNS diseases: the objective is to develop nanomedicines that would stimulate CNS repair by local, systemic, or mucosal delivery.
2. Regenerative medicine: this theme focuses on tissue regeneration and restoration and gathers the research on spinal cord regeneration, dental restoration and skin wound healing.