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Photo of Charles De Smet

Charles De Smet

Professeur ordinaire
charles.desmet@uclouvain.be

SSS/FASB Faculté de pharmacie et des sciences biomédicales (FASB)

SSS/DDUV Institut de Duve (DDUV)

SSS/DDUV/GEPI Epigénétique (GEPI)

Année Libellé Établissement
1994 Docteur en sciences UCLouvain | Université catholique de Louvain (Belgique)
1993 Diplômé d'études approfondies en biologie UCLouvain | Université catholique de Louvain (Belgique)
1987 Licencié en sciences pour le groupe des sciences zoologiques UCLouvain | Université catholique de Louvain (Belgique)
1985 Candidat en sciences pour le groupe des sciences biologiques UCLouvain | Université catholique de Louvain (Belgique)

Unités d'enseignement pour 2026

Libellé Code
Biologie et physiologie cellulaire LGBIO1111
Biologie générale WFASB1102
Biologie générale et approche expérimentale de la biologie WMD1120
Biologie et embryologie générale WMEDE1152
Biologie moléculaire (dont l'épigénétique) et travaux dirigés WSBIM1226
Embryologie WSBIM1310
Design expérimental en sciences biomédicales WSBIM1313
Séminaire d'accompagnement du mémoire en sciences biomédicales WSBIM2061
Génétique et épigénétique des tumeurs WSBIM2142
Special issues in cancerology WSBIM2244
In-session seminar in biomedicine WSBIM2245
Scientific communication workshop WSBIM2280

Les mécanismes épigénétiques sont essentiels pour établir et maintenir les programmes d'expression génique qui caractérisent les différents types cellulaires de l'organisme. La dérégulation de ces mécanismes peut entraîner des maladies, y compris le cancer. Les travaux de notre groupe de recherche portent sur les causes et les conséquences des altérations épigénétiques dans les tumeurs (lien vers le labo).

2026
Article de journal

Wangermez, C., Carlier, F., Lecocq, M., Pilette, C., & De Smet, C. (2026). Hypomethylation of FAM83A in lung adenocarcinoma mirrors an epigenetic signature of airway cell differentiation states. Discover Oncology, 17(1), 1154. https://doi.org/10.1007/s12672-026-05380-8 (Original work published 2026)

https://research.dial.uclouvain.be/handle/2078.5/279391


2025
Article de journal

Loriot, A., Devis, J., Gatto, L., & De Smet, C. (2025). A survey of human cancer-germline genes: Linking X chromosome localization, DNA methylation and sex-biased expression in early embryos. PLOS Genetics, 21(10), e1011734. https://doi.org/10.1371/journal.pgen.1011734 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/260600


2024
Article de journal

Fain, J., Wangermez, C., Loriot, A., Denoue, C., & De Smet, C. (2024). DNA Hypomethylation Underlies Epigenetic Swapping between AGO1 and AGO1-V2 Isoforms in Tumors. Epigenomes, 8(3), 24. https://doi.org/10.3390/epigenomes8030024 (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/273784


2023
Article de journal

Diacofotaki, A., Loriot, A., & De Smet, C. (2023). An abundance of brain-expressed genes show ectopic activation in lung adenocarcinoma. bioRxiv, 557389. https://doi.org/10.1101/2023.09.12.557389 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/102041


De Smet, C. (2023). DNA methylation profiling in early lung adenocarcinoma to predict response to immunotherapy. Translational Lung Cancer Research, 12(4), 657-660. https://doi.org/10.21037/tlcr-23-96 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/100263


2022
Article de journal

Diacofotaki, A., Loriot, A., & De Smet, C. (2022). Identification of tissue-specific gene clusters induced by DNA demethylation in lung adenocarcinoma: more than germline genes. Cancers, 14(4), 1007. https://doi.org/10.3390/cancers14041007 (Original work published 2022)

https://research.dial.uclouvain.be/handle/2078.5/110563


2021
Article de journal

Vander Linden, C., Corbet, C., Bastien, E., Martherus, R., Guilbaud, C., Petit, L., Wauthier, L., Loriot, A., De Smet, C., & Feron, O. (2021). Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition. Cell Reports, 35(9), 109202. https://doi.org/10.1016/j.celrep.2021.109202 (Original work published 2021)

https://research.dial.uclouvain.be/handle/2078.5/264681


Fain, J., Loriot, A., Diacofotaki, A., Van Tongelen, A., & De Smet, C. (2021). Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer. Scientific Reports, 11, 17346. https://doi.org/10.1038/s41598-021-96844-0 (Original work published 2021)

https://research.dial.uclouvain.be/handle/2078.5/112805


Viceconte, N., Loriot, A., Lona Abreu, P., Scheibe, M., Fradera Sola, A., Butter, F., De Smet, C., Azzalin, C. M., Arnoult, N., & Decottignies, A. (2021). PAR-TERRA is the main contributor to telomeric repeat-containing RNA transcripts in normal and cancer mouse cells. R N A, 27(1), 106-121. https://doi.org/10.1261/rna.076281.120 (Original work published 2021)

https://research.dial.uclouvain.be/handle/2078.5/117894


2019
Article de journal

Fain, J., Van Tongelen, A., Loriot, A., & De Smet, C. (2019). Epigenetic Coactivation of MAGEA6 and CT-GABRA3 Defines Orientation of a Segmental Duplication in the Human X Chromosome. Cytogenetic and Genome Research. Published. https://doi.org/10.1159/000502933 (Original work published 2019)

https://research.dial.uclouvain.be/handle/2078.5/245685


2017
Article de journal

De Pauw, A., Andre, E., Sekkali, B., Bouzin, C., Esfahani, H., Barbier, N., Loriot, A., De Smet, C., Vanhoutte, L., Moniotte, S., Gerber, B., di Mauro, V., Catalucci, D., Feron, O., Hilfiker-Kleiner, D., & Balligand, J.-L. (2017). Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction. JCI insight, 2(12). https://doi.org/10.1172/jci.insight.91810 (Original work published 2017)

https://research.dial.uclouvain.be/handle/2078.5/94736


Van Tongelen, A., Loriot, A., & De Smet, C. (2017). Oncogenic roles of DNA hypomethylation through the activation of cancer-germline genes. Cancer Letters, 396, 130-137. https://doi.org/10.1016/j.canlet.2017.03.029 (Original work published 2017)

https://research.dial.uclouvain.be/handle/2078.5/76158


2015
Article de journal

Cannuyer, J., Van Tongelen, A., Loriot, A., & De Smet, C. (2015). A gene expression signature identifying transient DNMT1 depletion as a causal factor of cancer-germline gene activation in melanoma. Clinical Epigenetics, 7(1), 114 [1-17]. https://doi.org/10.1186/s13148-015-0147-4 (Original work published 2015)

https://research.dial.uclouvain.be/handle/2078.5/188848


Van Tongelen, A., Loriot, A., De Backer, O., & De Smet, C. (2015). Application of CRISPR/cas9-Directed Homologous Recombination to the Generation of Human Tumor Cells with Conditional Knockout of an X-Linked MicroRNA Locus. Gene Technology, 04(02), 1000124. https://doi.org/10.4172/2329-6682.1000124 (Original work published 2015)

https://research.dial.uclouvain.be/handle/2078.5/190689


2014
Article de journal

Hendrickx, A., Pierrot, N., Tasiaux, B., Schakman, O., Kienlen-Campard, P., De Smet, C., & Octave, J.-N. (2014). Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease. PLoS One, 9(6), e99467 [1-9]. https://doi.org/10.1371/journal.pone.0099467 (Original work published 2014)

https://research.dial.uclouvain.be/handle/2078.5/195060


Loriot, A., Van Tongelen, A., Blanco, J., Klaessens, S., Cannuyer, J., van Baren, N., Decottignies, A., & De Smet, C. (2014). A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors. Epigenetics, 9(8), 1163-1171. https://doi.org/10.4161/epi.29628 (Original work published 2014)

https://research.dial.uclouvain.be/handle/2078.5/77399


2013
Article de journal

Hendrickx, A., Pierrot, N., Tasiaux, B., Schakman, O., Brion, J.-P., Kienlen-Campard, P., De Smet, C., & Octave, J.-N. (2013). Epigenetic induction of EGR-1 expression by the amyloid precursor protein during exposure to novelty. PLoS One, 8(9), e74305. https://doi.org/10.1371/journal.pone.0074305 (Original work published 2013)

https://research.dial.uclouvain.be/handle/2078.5/201292


Cannuyer, J., Loriot, A., Parvizi, G. K., & De Smet, C. (2013). Epigenetic Hierarchy within the MAGEA1 Cancer-Germline Gene: Promoter DNA Methylation Dictates Local Histone Modifications. PLoS One, 8(3), e58743. https://doi.org/10.1371/journal.pone.0058743 (Original work published 2013)

https://research.dial.uclouvain.be/handle/2078.5/163837


Chapitre de livre

De Smet, C., & Loriot, A. (2013). DNA hypomethylation and activation of germline-specific genes in cancer. In Adam R. Karpf (ed.), Epigenetic alterations in oncogenesis (pp. 149-166). Adam R. Karpf. https://doi.org/10.1007/978-1-4419-9967-2_7

https://research.dial.uclouvain.be/handle/2078.5/255555


2012
Article de journal

Loriot, A., Parvizi, G. K., Reister, S., & De Smet, C. (2012). Silencing of cancer-germline genes in human preimplantation embryos: evidence for active de novo DNA methylation in stem cells. Biochemical and Biophysical Research Communications, 417(1), 187-191. https://doi.org/10.1016/j.bbrc.2011.11.120 (Original work published 2012)

https://research.dial.uclouvain.be/handle/2078.5/34690


Lucas, S., van Baren, N., De Smet, C., & Coulie, P. (2012). Demethylation of the FOXP3 gene in human melanoma cells precludes the use of this epigenetic mark for quantification of Tregs in unseparated melanoma samples. International Journal of Cancer, 130(8), 1960-1966. https://doi.org/10.1002/ijc.26198 (Original work published 2012)

https://research.dial.uclouvain.be/handle/2078.5/205625


Tilman, G., Arnoult, N., Lenglez, S., Van Beneden, A., Loriot, A., De Smet, C., & Decottignies, A. (2012). Cancer-linked satellite 2 DNA hypomethylation does not regulate Sat2 non-coding RNA expression and is initiated by heat shock pathway activation. Epigenetics, 7(8), 903-913. https://doi.org/10.4161/epi.21107 (Original work published 2012)

https://research.dial.uclouvain.be/handle/2078.5/70441


2010
Article de journal

Bazhin, A. V., De Smet, C., Golovastova, M. O., Schmidt, J., & Philippov, P. P. (2010). Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells. Experimental Dermatology, 19(11), 1023-1025. https://doi.org/10.1111/j.1600-0625.2010.01126.x (Original work published 2010)

https://research.dial.uclouvain.be/handle/2078.5/39071


De Smet, C., & Loriot, A. (2010). DNA hypomethylation in cancer: Epigenetic scars of a neoplastic journey. Epigenetics : official journal of the DNA Methylation Society, 5(3). (Original work published 2010)

https://research.dial.uclouvain.be/handle/2078.5/32519


2009
Article de journal

Loriot, A., Reister, S., Parvizi, G. K., Lysy, P., & De Smet, C. (2009). DNA Methylation-Associated Repression of Cancer-Germline Genes in Human Embryonic and Adult Stem Cells. Stem Cells : the international journal of cell differentiation and proliferation, 27(4), 822-824. https://doi.org/10.1002/stem.8 (Original work published 2009)

https://research.dial.uclouvain.be/handle/2078.5/210113


Tilman, G., Loriot, A., Van Beneden, A., Arnoult, N., Londoño-Vallejo, J. A., De Smet, C., & Decottignies, A. (2009). Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells. Oncogene : including Oncogene Reviews, 28(14), 1682-1693. https://doi.org/10.1038/onc.2009.23 (Original work published 2009)

https://research.dial.uclouvain.be/handle/2078.5/64679


Stockis, J., Fink, W., François, V., Connerotte, T., De Smet, C., Knoops, L., van der Bruggen, P., Boon, T., Coulie, P., & Lucas, S. (2009). Comparison of stable human Treg and Th clones by transcriptional profiling. European Journal of Immunology, 39(3), 869-882. https://doi.org/10.1002/eji.200838807 (Original work published 2009)

https://research.dial.uclouvain.be/handle/2078.5/215597


2008
Article de journal

Loriot, A., Sterpin, C., De Backer, O., & De Smet, C. (2008). Mouse embryonic stem cells induce targeted DNA demethylation within human MAGE-A1 transgenes. Epigenetics : official journal of the DNA Methylation Society, 3(1), 38-42. (Original work published 2008)

https://research.dial.uclouvain.be/handle/2078.5/134914


Kholmanskikh, O., Loriot, A., Brasseur, F., De Plaen, E., & De Smet, C. (2008). Expression of BORIS in melanoma: lack of association with MAGE-A1 activation. International journal of cancer. Journal international du cancer, 122(4), 777-784. https://doi.org/10.1002/ijc.23140 (Original work published 2008)

https://research.dial.uclouvain.be/handle/2078.5/88602


2007
Article de journal

Bazhin, A. V., Schadendorf, D., Willner, N., De Smet, C., Heinzelmann, A., Tikhemirova, N. K., Umansky, V., Philippov, P. P., & Eichmüller, S. B. (2007). Photoreceptor proteins as cancer-retina antigens. International Journal of Cancer, 120(6), 1268-1276. https://doi.org/10.1002/ijc.22458 (Original work published 2007)

https://research.dial.uclouvain.be/handle/2078.5/205002


2006
Article de journal

Loriot, A., De Plaen, E., Boon, T., & De Smet, C. (2006). Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells. Journal of Biological Chemistry, 281(15), 10118-10126. https://doi.org/10.1074/jbc.M510469200 (Original work published 2006)

https://research.dial.uclouvain.be/handle/2078.5/132907


2005
Article de journal

Brenner, C., Deplus, R., Didelot, C., Loriot, A., Vire, E., De Smet, C., Gutierrez, A., Danovi, D., Bernard, D., Boon, T., Pelicci, P. G., Amati, B., Kouzarides, T., de Launoit, Y., Di Croce, L., & Fuks, F. (2005). Myc represses transcription through recruitment of DNA methyltransferase corepressor. The EMBO journal, 24(2), 336-346. https://doi.org/10.1038/sj.emboj.7600509 (Original work published 2005)

https://research.dial.uclouvain.be/handle/2078.5/95875


2004
Article de journal

Laduron, S., Deplus, R., Zhou, S., Kholmanskikh, O., GODELAINE, D., De Smet, C., Hayward, S. D., Fuks, F., Boon, T., & De Plaen, E. (2004). MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription. Nucleic Acids Research, 32(14), 4340-4350. https://doi.org/10.1093/nar/gkh735 (Original work published 2004)

https://research.dial.uclouvain.be/handle/2078.5/211985


De Smet, C., Loriot, A., & Boon, T. (2004). Promoter-dependent mechanism leading to selective hypomethylation within the 5 ′ region of gene MAGE-A1 in tumor cells. Molecular and Cellular Biology, 24(11), 4781-4790. https://doi.org/10.1128/MCB.24.11.4781-4790.2004 (Original work published 2004)

https://research.dial.uclouvain.be/handle/2078.5/97141


2003
Article de journal

Karanikas, V., Lurquin, C., Colau, D., van Baren, N., De Smet, C., Lethé, B., Connerotte, T., Corbiere, V., Demoitie, M., Lienard, D., Dréno, B., Velu, T., Boon, T., & Coulie, P. (2003). Monoclonal anti-MAGE-3 CTL responses in melanoma patients displaying tumor regression after vaccination with a recombinant canarypox virus. Journal of Immunology, 171(9), 4898-4904. https://doi.org/10.4049/jimmunol.171.9.4898 (Original work published 2003)

https://research.dial.uclouvain.be/handle/2078.5/211109


Loriot, A., Boon, T., & De Smet, C. (2003). Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. International Journal of Cancer, 105(3), 371-376. https://doi.org/10.1002/ijc.11104 (Original work published 2003)

https://research.dial.uclouvain.be/handle/2078.5/137148


Rousseau, E., Ruchoux, M.-M., Scaravilli, F., Chapon, F., Vinchon, M., De Smet, C., Godfraind, C., & Vikkula, M. (2003). CDKN2A, CDKN2B and p14ARF are frequently and differentially methylated in ependymal tumours. Neuropathology and Applied Neurobiology, 29(6), 574-583. https://doi.org/10.1046/j.0305-1846.2003.00505.x (Original work published 2003)

https://research.dial.uclouvain.be/handle/2078.5/77700


2002
Article de journal

De Smet, C., Nishimori, H., Furnari, F. B., Bögler, O., Huang, H.-J. S., & Cavenee, W. K. (2002). A novel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression. Journal of neurochemistry, 81(3), 575-588. (Original work published 2002)

https://research.dial.uclouvain.be/handle/2078.5/201290


2000
Article de journal

Martelange, V., De Smet, C., De Plaen, E., Lurquin, C., & Boon, T. (2000). Identification on a human sarcoma of two new genes with tumor-specific expression. Cancer research, 60(14), 3848-3855. (Original work published 2000)

https://research.dial.uclouvain.be/handle/2078.5/76560


1999
Article de journal

De Smet, C., Lurquin, C., Lethé, B., Martelange, V., & Boon, T. (1999). DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter. Molecular and Cellular Biology, 19(11), 7327-7335. https://doi.org/10.1128/mcb.19.11.7327 (Original work published 1999)

https://research.dial.uclouvain.be/handle/2078.5/140351


De Backer, O., Arden, K. C., Boretti, M., Vantomme, V., De Smet, C., Czekay, S., Viars, C. S., De Plaen, E., Brasseur, F., Chomez, P., Van den Eynde, B., Boon-Falleur, T., & van der Bruggen, P. (1999). Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. Cancer Research, 59(13), 3157-3165. (Original work published 1999)

https://research.dial.uclouvain.be/handle/2078.5/130583


Louahed, J., Grasso, L., De Smet, C., Van Roost, E., Wildmann, C., Nicolaides, N. C., Levitt, R. C., & Renauld, J.-C. (1999). Interleukin-9-induced expression of M-Ras/R-Ras3 oncogene in T-helper clones. Blood, 94(5), 1701-1710. https://doi.org/10.1182/blood.V94.5.1701 (Original work published 1999)

https://research.dial.uclouvain.be/handle/2078.5/140453


Janssen, B., van de Locht, L., Fourkour, A., De Smet, C., Mensink, E., van Muijen, G., & de Vries, T. (1999). Transcription of the MAGE-1 gene and the methylation status of its Ets binding promoter elements: a quantitative analysis in melanoma cell lines using a real-time polymerase chain reaction technique. Melanoma Research : an international journal of rapid communications of basic and clinical research in melanoma, 9(3), 213-222. https://doi.org/10.1097/00008390-199906000-00002 (Original work published 1999)

https://research.dial.uclouvain.be/handle/2078.5/140501


1998
Article de journal

Lucas, S., De Smet, C., Arden, KC., Viars, C., Lethé, B., Lurquin, C., & Boon, T. (1998). Identification of a new MAGE gene with tumor-specific expression by representational difference analysis. Cancer Research, 58(4), 743-752. (Original work published 1998)

https://research.dial.uclouvain.be/handle/2078.5/142004


Lethé, B., Lucas, S., Michaux, L., De Smet, C., Godelaine, D., Serrano, A., De Plaen, E., & Boon, T. (1998). LAGE-1, a new gene with tumor specificity. International journal of cancer. Journal international du cancer, 76(6), 903-908. https://doi.org/10.1002/(SICI)1097-0215(19980610)76:6<903::AID-IJC22>3.0.CO;2-1 (Original work published 1998)

https://research.dial.uclouvain.be/handle/2078.5/135814


1997
Article de journal

Lurquin, C., De Smet, C., Brasseur, F., Muscatelli, F., Martelange, V., De Plaen, E., Brasseur, R., Monaco, A. P., & Boon-Falleur, T. (1997). Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins. Genomics, 46(3), 397-408. https://doi.org/10.1006/geno.1997.5052 (Original work published 1997)

https://research.dial.uclouvain.be/handle/2078.5/129388


De Smet, C., Martelange, V., Lucas, S., Brasseur, F., Lurquin, C., & Boon-Falleur, T. (1997). Identification of human testis-specific transcripts and analysis of their expression in tumor cells. Biochemical and Biophysical Research Communications, 241(3), 653-657. https://doi.org/10.1006/bbrc.1997.7868 (Original work published 1997)

https://research.dial.uclouvain.be/handle/2078.5/142087


De Smet, C., Lurquin, C., De Plaen, E., Brasseur, F., Zarour, H., De Backer, O., Coulie, P., & Boon-Falleur, T. (1997). Genes coding for melanoma antigens recognised by cytolytic T lymphocytes. Eye, 11, 243-248. https://doi.org/10.1038/eye.1997.59 (Original work published 1997)

https://research.dial.uclouvain.be/handle/2078.5/210800


Ikeda, H., Lethé, B., Lehmann, F., van Baren, N., Baurain, J.-F., De Smet, C., Chambost, H., Vitale, M., Moretta, A., Boon-Falleur, T., & Coulie, P. (1997). Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. Immunity, 6(2), 199-208. https://doi.org/10.1016/S1074-7613(00)80426-4 (Original work published 1997)

https://research.dial.uclouvain.be/handle/2078.5/211796


De Plaen, E., Naerhuyzen, B., De Smet, C., Szikora, J.-P., & Boon-Falleur, T. (1997). Alternative promoters of gene MAGE4a. Genomics, 40(2), 305-313. https://doi.org/10.1006/geno.1996.4566 (Original work published 1997)

https://research.dial.uclouvain.be/handle/2078.5/143177


1996
Article de journal

De Smet, C., Debacker, O., Faraoni, I., Lurquin, C., Brasseur, F., & Boon, T. (1996). The activation of human gene MAGE-1 in tumor cells is correlated with genome-wide demethylation. National Academy of Sciences. Proceedings, 93(14), 7149-7153. https://doi.org/10.1073/pnas.93.14.7149 (Original work published 1996)

https://research.dial.uclouvain.be/handle/2078.5/77262


Zarour, H., De Smet, C., Lehmann, F., Marchand, M., Lethé, B., Romero, P., Boon, T., & Renauld, J.-C. (1996). The majority of autologous cytolytic T-lymphocyte clones derived from peripheral blood lymphocytes of a melanoma patient recognize an antigenic peptide derived from gene Pmel17/gp100. The Journal of Investigative Dermatology, 107(1), 63-67. https://doi.org/10.1111/1523-1747.ep12298177 (Original work published 1996)

https://research.dial.uclouvain.be/handle/2078.5/51607


1995
Article de journal

De Smet, C., Courtois, SJ., Faraoni, I., Lurquin, C., Szikora, J.-P., Debacker, O., & Boon, T. (1995). Involvement of 2 Ets Binding-sites in the Transcriptional Activation of the Mage1 Gene. Immunogenetics, 42(4), 282-290. (Original work published 1995)

https://research.dial.uclouvain.be/handle/2078.5/144769


1994
Article de journal

van der Bruggen, P., Bastin, J., Gajewski, T., Coulie, P., Boël, P., De Smet, C., Traversari, C., Townsend, A., & Boon-Falleur, T. (1994). A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3. European Journal of Immunology, 24(12), 3038-3043. https://doi.org/10.1002/eji.1830241218 (Original work published 1994)

https://research.dial.uclouvain.be/handle/2078.5/211810


De Plaen, E., Arden, K., Traversari, C., Gaforio, J. J., Szikora, J.-P., De Smet, C., Brasseur, F., van der Bruggen, P., Lethé, B., Lurquin, C., Brasseur, R., Chomez, P., De Backer, O., Cavenee, W., & Boon-Falleur, T. (1994). Structure, Chromosomal Localization, and Expression of 12 Genes of the Mage Family. Immunogenetics, 40(5), 360-369. https://doi.org/10.1007/BF01246677 (Original work published 1994)

https://research.dial.uclouvain.be/handle/2078.5/145720


De Smet, C., Lurquin, C., van der Bruggen, P., De Plaen, E., Brasseur, F., & Boon-Falleur, T. (1994). Sequence and Expression Pattern of the Human Mage2 Gene. Immunogenetics, 39(2), 121-129. https://doi.org/10.1007/BF00188615 (Original work published 1994)

https://research.dial.uclouvain.be/handle/2078.5/146465


1992
Article de journal

Dyson, PJ., De Smet, C., Knight, AM., Simonchazottes, D., Guénet, J.-L., & Boon, T. (1992). Mapping of the Genes Encoding Tum- Transplantation Antigen-p91a, Antigen-p35b, and Antigen-p198. Immunogenetics. https://doi.org/10.1007/BF00189894

https://research.dial.uclouvain.be/handle/2078.5/137160


Dyson, P. J., De Smet, C., Knight, A. M., Simon-Chazottes, D., Guénet, J. L., & Boon, T. (1992). Mapping of the genes encoding tum- transplantation antigens P91A, P35B, and P198. Immunogenetics, 35(5), 316-323. (Original work published 1992)

https://research.dial.uclouvain.be/handle/2078.5/51000


Chomez, P., De Plaen, E., Van Pel, A., De Smet, C., Szikora, J.-P., Lurquin, C., Lebacqverheyden, AM., & Boon, T. (1992). Efficient Expression of Tum- Antigen P91a By Transfected Subgenic Fragments. Immunogenetics, 35(4), 241-252. https://doi.org/10.1007/BF00166829 (Original work published 1992)

https://research.dial.uclouvain.be/handle/2078.5/137179