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- Lisa Leyssens
Lisa Leyssens
Assistante
A microCT-based approach for the characterization of biodegradable metallic intravascular stents
The goal of my research project is to optimize high-resolution 3D microfocus X-ray computed tomography (microCT) and contrast-enhanced microCT (CECT) for the characterization of the microstructure of blood vessels in a first instance. Then, this technique is applied to study the degradation behaviour of potential materials for biodegradable metallic intravascular stents, both in vitro and in vivo.
2023
Leyssens, Lisa ; Balcaen, Tim ; Pétré, Maïté ; Bejar Ayllon, Natalia ; El Aazmani, Walid ; de Pierpont, Alix ; Pyka, Grzegorz ; Lacroix, Valérie ; Kerckhofs, Greet. Non-destructive 3D characterization of the blood vessel wall microstructure in different species and blood vessel types using contrast-enhanced microCT and comparison with synthetic vascular grafts. In: Acta Biomaterilia, Vol. 164, no.164, p. 303-316 (2023). doi:10.1016/j.actbio.2023.04.013.
2022
Maes, Arne ; Pestiaux, Camille ; Marino, Alice ; Balcaen, Tim ; Leyssens, Lisa ; Vangrunderbeeck, Sarah ; Pyka, Grzegorz ; De Borggraeve, Wim M. ; Bertrand, Luc ; Beauloye, Christophe ; Horman, Sandrine ; Wevers, Martine ; Kerckhofs, Greet. Cryogenic contrast-enhanced microCT enables nondestructive 3D quantitative histopathology of soft biological tissues. In: Nature Communications, Vol. 13, no.1, p. - (2022). doi:10.1038/s41467-022-34048-4.
2022
Léger, Jean ; Leyssens, Lisa ; Kerckhofs, Greet ; De Vleeschouwer, Christophe. Ensemble learning and test-time augmentation for the segmentation of mineralized cartilage versus bone in high-resolution microCT images. In: Computers in Biology and Medicine, Vol. 148, no.-, p. 105932 (2022). doi:10.1016/j.compbiomed.2022.105932.
2021
Leyssens, Lisa ; Pestiaux, Camille ; Kerckhofs, Greet. A Review of Ex Vivo X-ray Microfocus Computed Tomography-Based Characterization of the Cardiovascular System. In: International Journal of Molecular Sciences, Vol. 22, no.6, p. 3263 (2021). doi:10.3390/ijms22063263.
2023
Leyssens, Lisa ; Lapraille, Noémie ; Pyka, Grzegorz ; Jacques, Pascal ; Horman, Sandrine ; Goldman, Jeremy ; Kerckhofs, Greet. Exploring the biodegradability and biocompatibility of candidate metallic intravascular stent materials using microCT and CECT.. 15th Biometal conference (Cetraro, du 21/08/2023 au 27/08/2023).
2022
Pestiaux, Camille ; Maes, Arne ; Balcaen, Tim ; Leyssens, Lisa ; Vangrunderbeeck, Sarah ; Pyka, Grzegorz ; De Borggraeve, Wim M. ; Bertrand, Luc ; Beauloye, Christophe ; Horman, Sandrine ; Wevers, Martine ; Kerckhofs, Greet. Cryogenic Contrast-Enhanced MicroCT (cryo-CECT): a Novel Nondestructive Approach to 3D Quantitative Histopathology of Soft Biological Tissues. Tomography for Scientific Advancement UK and Europe 2022 (London, UK, du 07/09/2022 au 09/09/2022).
2022
Leyssens, Lisa. Optimization of contrast-enhanced microCT for vascular applications. 5th International Conference on Tomography of Materials and Structures (Grenoble, du 27/06/2022 au 01/07/2022).
2022
Pétré, Maïté ; Leyssens, Lisa ; El Aazmani, Walid ; Balcaen, Tim ; Fehervary, Heleen ; Famaey, Nele ; Kerckhofs, Greet. Screening of contrast-enhancing staining agents for 4D contrast-enhanced microCT of vascular tissues. World Conference of Biomechanics (Tapei, Tawain, du 10/07/2022 au 14/07/2022).
2021
Leyssens, Lisa ; Pétré, Maïté ; Kerckhofs, Greet. Optimization of MicroCT and CECT for Cardiovascular Applications. 17th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and the 5th Conference on Imaging (Online, du 07/09/2021 au 09/09/2021).
2021
Leyssens, Lisa ; Kerckhofs, Greet. Optimization of microCT and CECT for cardiovascular applications. ToScA (Online, du 01/09/2021 au 03/09/2021).
2019
Maes, Arne ; Leyssens, Lisa ; Kerckhofs, Greet. ADVANCED CHARACTERIZATION OF THE 3D MORPHOLOGY OF THE BONE-TENDON INTERFACE. ESB 2019 (Vienna, Austria, du 07/07/2019 au 10/07/2019).
2019
Arne Maes ; Leyssens, Lisa ; Carla Geeroms ; Kerckhofs, Greet. ADVANCED CHARACTERIZATION OF THE 3D MORPHOLOGY OF THE BONE-TENDON INTERFACE TOWARDS REGENERATIVE TREATMENTS. BSTE 2019 (Hasselt, du 14/11/2019 au 15/11/2019).
2019
Leyssens, Lisa. Advanced characterization of the 3D morphology and the mechanical properties of the enthesis: optimization study. CMBBE 2019 (New York, du 14/08/2019 au 16/08/2019).
2019
Leyssens, Lisa ; Bejar Ayllon, Natalia. Arterial grafts: in depth characterization of structure and mechanical properties. BSTE 2019 (Hasselt, du 14/11/2019 au 15/11/2019).
2019
Léger, Jean ; Leyssens, Lisa ; De Vleeschouwer, Christophe ; Kerckhofs, Greet. Deep learning-based segmentation of mineralized cartilage and bone in high-resolution micro-CT images. 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (New York City, du 14/08/2019 au 16/08/2019) (Accepté/Sous presse).
2019
Leyssens, Lisa ; Ryelandt, Sophie ; Favache, Audrey ; Kerckhofs, Greet. Nanoindentation of biological tissues: opportunities and challenges for the bone-tendon interface. ESB 2019 (Vienna, du 07/07/2019 au 10/07/2019).
2019
Leyssens, Lisa. Optimization of contrast-enhanced micro-CT for characterization of the in vivo behavior of biodegradable metallic intravascular stents. CMBBE 2019 (New York, du 14/08/2019 au 16/08/2019).
2018
Leyssens, Lisa ; Ryelandt, Sophie ; Favache, Audrey ; Kerckhofs, Greet. Nanoindentation of biological tissues: opportunities and challenges for the bone-tendon interface. Indentation 2018 (Liège, du 11/09/2018 au 14/09/2018).