DDUV
Avenue Hippocrate 74/B1.74.03
1200 Woluwe-Saint-Lambert
- Accueil
- Répertoire
- Pierre van der Bruggen
Pierre van der Bruggen
Chercheur
Professeur extraordinaire
- Diplômes
Année Label Institution 1979 Candidat ingénieur agronome Université catholique de Louvain 1982 Ingénieur agronome Université catholique de Louvain 1988 Docteur en sciences agronomiques Université catholique de Louvain
- Les cours
Nom ID Maladies inflammatoires, auto-immunitaires et cancer: aspects immunologiques WSBIM2116
2024
Delhez, Nicolas ; Aboubakar Nana, Frank ; Houbion, Camille ; Bayard, Alexandre ; Bruger, Annika ; Vanhaver, Christophe ; Brandau, Sven ; van der Bruggen, Pierre ; Hirsch, Thibault. Deciphering neutrophil heterogeneity in human blood and tumors: Methods for isolating neutrophils and assessing their effect on T-cell proliferation. In: Methods in Cell Biology, Vol. /, no./, p. / (2024). doi:10.1016/bs.mcb.2024.10.010.
2024
Hirsch, Thibault ; Neyens, Damien ; Duhamel, Céline ; Bayard, Alexandre ; Vanhaver, Christophe ; Luyckx, Mathieu ; Sala de Oyanguren, F ; Wildmann, Claude ; Dauguet, Nicolas ; Squifflet, Jean-Luc ; Montiel, Virginie ; Deschamps, Mélanie ; van der Bruggen, Pierre. IRF4 Impedes Human CD8 T-Cell Function and Promotes Cell Proliferation and PD-1 Expression. In: Cell Reports, Vol. 43, no.7, p. 114401 (2024).
2023
Neyens, Damien ; Hirsch, Thibault (co-first author) ; Abdel Aziz Issa Abdel Hadi, Achraqat ; Dauguet, Nicolas ; Vanhaver, Christophe ; Bayard, Alexandre ; Wildmann, Claude ; Luyckx, Mathieu ; Squifflet, Jean-Luc ; D’Hondt, Quentin ; Duhamel, Céline ; Huaux, Antoine ; Montiel, Virginie ; Dechamps, Mélanie ; van der Bruggen, Pierre. HELIOS-expressing human CD8 T cells exhibit limited effector functions. In: Frontiers in Immunology, Vol. 14 (2023). doi:10.3389/fimmu.2023.1308539.
2023
Vanhaver, Christophe ; Aboubakar Nana, Frank (co-first author) ; Delhez, Nicolas ; Luyckx, Mathieu ; Hirsch, Thibault ; Bayard, Alexandre ; Houbion, Camille ; Dauguet, Nicolas ; Brochier, Alice ; van der Bruggen, Pierre ; Bruger, Annika. Immunosuppressive low-density neutrophils in the blood of cancer patients display a mature phenotype. In: Life Science Alliance, Vol. 7, no.1, p. e202302332 (2023). doi:10.26508/lsa.202302332.
2021
Gondois-Rey, Françoise ; Paul, Magali ; Alcaraz, Florence ; Bourass, Sarah ; Monnier, Jilliana ; Malissen, Nausicaa ; Grob, Jean-Jacques ; Bruger, Annika M ; van der Bruggen, Pierre ; Gaudy-Marqueste, Caroline ; Olive, Daniel. Identification of an Immature Subset of PMN-MDSC Correlated to Response to Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma.. In: Cancers, Vol. 13, no.6, p. 1362 (2021). doi:10.3390/cancers13061362.
2021
Vanhaver, Christophe ; van der Bruggen, Pierre ; Bruger, Annika M. MDSC in Mice and Men: Mechanisms of Immunosuppression in Cancer.. In: Journal of clinical medicine, Vol. 10, no.13 (2021). doi:10.3390/jcm10132872.
2020
Leoni, Guido ; D'Alise, Anna Morena ; Cotugno, Gabriella ; Langone, Francesca ; Garzia, Irene ; De Lucia, Maria ; Fichera, Imma ; Vitale, Rosa ; Bignone, Veronica ; Tucci, Fabio Giovanni ; Mori, Federica ; Leuzzi, Adriano ; Di Matteo, Elena ; Troise, Fulvia ; Abbate, Adele ; Merone, Rossella ; Ruzza, Valentino ; Diodoro, Maria Grazia ; Yadav, Mahesh ; Gordon-Alonso, Monica ; Vanhaver, Christophe ; Panigada, Maddalena ; Soprana, Elisa ; Siccardi, Antonio ; Folgori, Antonella ; Colloca, Stefano ; Van Der Bruggen, Pierre ; Nicosia, Alfredo ; Lahm, Armin ; Catanese, Maria Teresa ; Scarselli, Elisa. A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability.. In: Cancer research, Vol. 80, no. 18, p. 3972-3982 (2020). doi:10.1158/0008-5472.CAN-20-1072.
2020
Renard, Henri-François ; Tyckaert, François ; Lo Giudice, Maria ; Hirsch, Thibault ; Valades-Cruz, Cesar Augusto ; Lemaigre, Camille ; Shafaq-Zadah, Massiullah ; Wunder, Christian ; Wattiez, Ruddy ; Johannes, Ludger ; van der Bruggen, Pierre ; Alsteens, David ; Morsomme, Pierre. Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166. In: Nature Communications, Vol. 11, no.1, p. 1457 (2020). doi:10.1038/s41467-020-15303-y.
2020
Bruger, Annika ; Vanhaver, Christophe ; Bruderek, Kirsten ; Amodio, Giada ; Tavukçuoğlu, Ece ; Esendagli, Günes ; Gregori, Silvia ; Brandau, Sven ; van der Bruggen, Pierre. Protocol to assess the suppression of T-cell proliferation by human MDSC.. In: Methods in enzymology, Vol. 632, p. 155-192 (2020). doi:10.1016/bs.mie.2019.05.046.
2020
Vanhaver, Christophe ; Gordon-Alonso, Monica ; Bayard, Alexandre ; Catanese, Maria Teresa ; Colau, Didier ; van der Bruggen, Pierre ; Bruger, Annika M. Reverse immunology: From peptide sequence to tumor-killing human T-cell clones.. In: Methods in enzymology, Vol. 631, no.1, p. 159-194 (2020). doi:10.1016/bs.mie.2019.05.033.
2018
Gordon-Alonso, Monica ; Bruger, Annika ; van der Bruggen, Pierre. Extracellular galectins as controllers of cytokines in hematological cancer. In: Blood: The Journal of Hematology, (2018).
2018
Bruger, Annika ; Dorhol, Anca ; Esendagli, Gunes ; Barczyk-Kahlert, Katarzyna ; van der Bruggen, Pierre ; Lipoldova, Marie ; Perecko, Tomas ; Santibanez, Juan ; Saralva, Margarida ; Van Ginderachter, Jo A ; Brandau, Sven. How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions. In: Cancer Immunology, Immunotherapy : other biological response modifications, Vol. 68, no. 4, p. 631-644 (2019). doi:10.1007/s00262-018-2170-8.
2018
Boon, Lise ; Ugarte‐Berzal, Estefania ; Martens, Erik ; Vandooren, Jennifer ; Rybakin, Vasily ; Colau, Didier ; Gordon‐Alonso, Monica ; van der Bruggen, Pierre ; Stöcker, Walter ; Becker‐Pauly, Christoph ; Witters, Peter ; Morava, Eva ; Jaeken, Jaak ; Proost, Paul ; Opdenakker, Ghislain. Propeptide glycosylation and galectin‐3 binding decrease proteolytic activation of human proMMP‐9/progelatinase B. In: The FEBS Journal, Vol. 286, no. 5, p. 930-945 (2018). doi:10.1111/febs.14698.
2018
Ma, Wenbin ; Stroobant, Vincent ; Heirman, Carlo ; Sun, Zhaojun ; Thielemans, Kris ; Mulder, Arend ; van der Bruggen, Pierre ; Van den Eynde, Benoît. The Vacuolar Pathway of Long Peptide Cross-Presentation Can Be TAP Dependent. In: The Journal of Immunology, Vol. 202, no.2, p. 451-459 (2018). doi:10.4049/jimmunol.1800353.
2017
Chen, Xinfeng ; Wang, Liping ; Yue, Dongli ; Liu, Jinyan ; Huang, Lan ; Yang, Li ; Cao, Ling ; Qin, Guohui ; Li, Anqi ; Wang, Dan ; Wang, Meng ; Qi, Yu ; Zhang, Bin ; van der Bruggen, Pierre ; Zhang, Yi. Correlation between the high expression levels of cancer-germline genes with clinical characteristics in esophageal squamous cell carcinoma.. In: Histology and Histopathology : cellular and molecular biology, Vol. 32, no.8, p. 793-803 (2017). doi:10.14670/HH-11-847.
2017
Chen, Xinfeng ; Wang, Liping ; Liu, Jinyan ; Huang, Lan ; Yang, Li ; Gao, Qun ; Shi, Xiaojuan ; Li, Jieyao ; Li, Feng ; Zhang, Zhen ; Zhao, Song ; Zhang, Bin ; Van der Bruggen, Pierre ; Zhang, Yi. Expression and prognostic relevance of MAGE-A3 and MAGE-C2 in non-small cell lung cancer.. In: Oncology Letters, Vol. 13, no.3, p. 1609-1618 (2017). doi:10.3892/ol.2017.5665.
2017
Gordon-Alonso, Monica ; Hirsch, Thibault ; Wildmann, Claude ; van der Bruggen, Pierre. Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration. In: Nature Communications, Vol. 8, p. 793 (2017). doi:10.1038/s41467-017-00925-6.
2017
Lu, Yong-Chen ; Parker, Linda L ; Lu, Tangying ; Zheng, Zhili ; Toomey, Mary Ann ; White, Donald E ; Yao, Xin ; Li, Yong F ; Robbins, Paul F ; Feldman, Steven A ; van der Bruggen, Pierre ; Klebanoff, Christopher A ; Goff, Stephanie L ; Sherry, Richard M ; Kammula, Udai S ; Yang, James C ; Rosenberg, Steven A. Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3. In: Journal of Clinical Oncology, Vol. 35, p. 3322-3329 (2017). doi:10.1200/JCO.2017.74.5463.
2016
Petit, Anne-Elisabeth ; Demotte, Nathalie ; Scheid, Benoît ; Wildmann, Claude ; Bigirimana, René ; Gordon-Alonso, Monica ; Carrasco, Javier ; Valitutti, Salvatore ; Godelaine, Danièle ; van der Bruggen, Pierre. A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion. In: Nature Communications, Vol. 7, p. 12242 [1-15] (2016). doi:10.1038/ncomms12242.
2016
Connelley, Timothy K. ; Li, Xiaoying ; MacHugh, Niall ; Colau, Didier ; Graham, Simon P. ; van der Bruggen, Pierre ; Taracha, Evans L. ; Gill, Andy ; Morrison, William Ivan. CD8 T-cell responses against the immunodominant Theileria parvapeptide Tp249-59are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes. In: Immunology : the journal of cells, molecules, system and technologies, Vol. 149, no.2, p. 172-185 (2016). doi:10.1111/imm.12637.
2016
Yao, Xin ; Lu, Yong-Chen ; Parker, Linda L. ; Li, Yong F. ; El-Gamil, Mona ; Black, Mary A. ; Xu, Hui ; Feldman, Steven A. ; van der Bruggen, Pierre ; Rosenberg, Steven A. ; Robbins, Paul F.. Isolation and Characterization of an HLA-DPB1*04. In: Journal of Immunotherapy, Vol. 39, no.5, p. 191-201 (2016). doi:10.1097/CJI.0000000000000123.
2016
Ma, Wenbin ; Zhang, Yi ; Vigneron, Nathalie ; Stroobant, Vincent ; Thielemans, Kris ; van der Bruggen, Pierre ; Van den Eynde, Benoît. Long-Peptide Cross-Presentation by Human Dendritic Cells Occurs in Vacuoles by Peptide Exchange on Nascent MHC Class I Molecules.. In: Journal of Immunology, Vol. 196, no.4, p. 1711-1720 (2016). doi:10.4049/jimmunol.1501574.
2016
Huaux, François ; d'Ursel de Bousies, Virginie ; Parent, Marie-Astrid ; Orsi, Micaela ; Uwambayinema, Francine ; Devosse, Raynal ; Ibouraadaten, Saloua ; Yakoub, Yousof ; Panin, Nadtha ; Palmai-Pallag, Mihaly ; van der Bruggen, Pierre ; Bailly, Christian ; Marega, Riccardo ; Marbaix, Etienne ; Lison, Dominique. Mesothelioma response to carbon nanotubes is associated with an early and selective accumulation of immunosuppressive monocytic cells.. In: Particle and Fibre Toxicology, Vol. 13, no. 1, p. 46 [1-10] (2016). doi:10.1186/s12989-016-0158-0.
2015
Apetoh, Lionel ; Smyth, Mark ; Drake, Charles ; Abastado, Jean-Pierre ; Apte, Ron ; Ayyoub, Maha ; Blay, Jean-Yves ; Bonneville, Marc ; Butterfield, Lisa ; Caignard, Anne ; Castelli, Chiara ; Cavallo, Federica ; Celis, Esteban ; Chen, Lieping ; Colombo, Mario ; Comin-Anduix, Begonya ; Coukos, Georges ; Dhodapkar, Madhav ; Dranoff, Glenn ; Frazer, Ian ; Fridman, Wolf-Hervé ; Gabrilovich, Dmitry ; Gilboa, Eli ; Jäger, Dirk ; Gnjatic, Sacha ; Kalinski, Pawel ; Kaufman, Howard ; Kiessling, Rolf ; Kirkwood, John ; Knuth, Alexander ; Liblau, Roland ; Lotze, Michaël ; Lugli, Enrico ; Marincola, Francesco ; Melero, Ignacio ; Melief, Cornelis ; Mempel, Thorsten ; Mittendorf, Elisabeth ; Odnusi, Kunle ; Overwijk, Willem ; Palucka, Anna Karolina ; Parmiani, Giorgio ; Ribas, Antoni ; Romero, Pedro ; Schreiber, Robert ; Schuler, Gerold ; Srivastava, Pramod ; Tartour, Eric ; Valmori, Danila ; Van der Burg, Sjoerd ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Wang, Ena ; Zou, Weiping ; Yee, Cassian ; Whiteside, Theresa ; Speiser, Daniel ; Pardoll, Drew ; Restifo, Nicholas ; Anderson, Ana. Consensus nomenclature for CD8 T cell phenotypes in cancer. In: OncoImmunology, (2015) (Accepté/Sous presse).
2015
Obenaus, Matthias ; Leitao, Catarina ; Leisegang, Matthias ; Chen, Xiaojing ; Gavvovidis, Ioannis ; van der Bruggen, Pierre ; Uckert, Wolfgang ; Schendel, Dolores ; Blanckenstein, Thomas. Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice. In: Nature Biotechnology, Vol. 33, no. 4, p. 402-407 (2015) (Accepté/Sous presse).
2014
Demotte, Nathalie ; Bigirimana, René ; Wieërs, Grégoire ; Stroobant, Vincent ; Squifflet, Jean-Luc ; Carrasco, Javier ; Thielemans, Kris ; Baurain, Jean-François ; Van Der Smissen, Patrick ; Courtoy, Pierre J ; van der Bruggen, Pierre. A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes.. In: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, no.7, p. 1823-33 (2014). doi:10.1158/1078-0432.CCR-13-2459 (Soumis).
2014
Abad, Sébastien ; Wieers, Grégoire ; Colau, Didier ; Wildmann, Claude ; Delair, Emmanuelle ; Dhote, Robin ; Brézin, Antoine P. ; Kawakami, Yukata ; Coulie, Pierre G. ; van der Bruggen, Pierre. Absence of recognition of common melanocytic antigens by T cells isolated from the cerebrospinal fluid of a Vogt-Koyanagi-Harada patient. In: Molecular Vision, Vol. 20, p. 956-969 (2014).
2014
Gordon-Alonso, Monica ; Demotte, Nathalie ; van der Bruggen, Pierre. Sugars boost exhausted tumor-infiltrating lymphocytes by counteracting immunosuppressive activities of galectins. In: OncoImmunology, Vol. 3, no.5, p. e28783 (2014). doi:10.4161/onci.28783.
2014
Coulie, Pierre G. ; Van den Eynde, Benoît ; van der Bruggen, Pierre ; Boon-Falleur, Thierry. Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy.. In: Nature Reviews. Cancer, Vol. 14, no.2, p. 135-146 (2014). doi:10.1038/nrc3670.
2013
Vigneron, Nathalie ; Stroobant, Vincent ; Van den Eynde, Benoît ; van der Bruggen, Pierre. Database of T cell-defined human tumor antigens: the 2013 update.. In: Cancer Immunity, Vol. 13, p. 15 (2013).
2013
van der Bruggen, Pierre ; Stroobant, Vincent ; Vigneron, Nathalie ; Van den Eynde, Benoît. Peptide database of T-cell defined tumor antigens. In: Cancer Immunity, (2013).
2012
Van Nuffel, An M T ; Benteyn, Daphné ; Wilgenhof, Sofie ; Pierret, Lauranne ; Corthals, Jurgen ; Heirman, Carlo ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Neyns, Bart ; Thielemans, Kris ; Bonehill, Aude. Dendritic cells loaded with mRNA encoding full-length tumor antigens prime CD4+ and CD8+ T cells in melanoma patients.. In: Molecular Therapy, Vol. 20, no. 5, p. 1063-1074 (2012). doi:10.1038/mt.2012.11.
2012
Lorenzi, Silvia ; Forloni, Matteo ; Cifaldi, Loredana ; Antonucci, Chiara ; Citti, Arianna ; Boldrini, Renata ; Pezzullo, Marco ; Castellano, Aurora ; Russo, Vincenzo ; van der Bruggen, Pierre ; Giacomini, Patrizio ; Locatelli, Franco ; Fruci, Doriana. IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma.. In: PLoS One, Vol. 7, no.10, p. e46928 (2012). doi:10.1371/journal.pone.0046928.
2012
Stroobant, Vincent ; Demotte, Nathalie ; Luiten, Rosalie M ; Leonhardt, Ralf M ; Cresswell, Peter ; Bonehill, Aude ; Michaux, Alexandre ; Ma, Wenbin ; Mulder, Arend ; Van den Eynde, Benoît ; van der Bruggen, Pierre ; Vigneron, Nathalie. Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells. In: European Journal of Immunology, Vol. 42, no. 6, p. 1417-1428 (2012). doi:10.1002/eji.201141954.
2012
Antonopoulos, Aristotelis ; Demotte, Nathalie ; Stroobant, Vincent ; Haslam, Stuart M ; van der Bruggen, Pierre ; Dell, Anne. Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation.. In: The Journal of biological chemistry, Vol. 287, no.14, p. 11240-51 (2012). doi:10.1074/jbc.M111.320820.
2012
Straetemans, Trudy ; van Brakel, Mandy ; van Steenbergen, Sabine ; Broertjes, Marieke ; Drexhage, Joost ; Hegmans, Joost ; Lambrecht, Bart N ; Lamers, Cor ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Debets, Reno. TCR gene transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 epitopes as melanoma-specific immune targets.. In: Clinical & Developmental Immunology, Vol. 2012, no.00, p. 586314 (2012). doi:10.1155/2012/586314.
2011
Wieers, Grégoire ; Demotte, Nathalie ; Godelaine, Danièle ; van der Bruggen, Pierre. Immune suppression in tumors as a surmountable obstacle to clinical efficacy of cancer vaccines. In: Cancers, Vol. 3, no. 3, p. 2904-2954 (2011). doi:10.3390/cancers3032904.
2010
Demotte, Nathalie ; Wieers, Grégoire ; Van Der Smissen, Patrick ; Moser, Muriel ; Schmidt, Christopher ; Thielemans, Kris ; Squifflet, Jean-Luc ; Weynand, Birgit ; Carrasco, Javier ; Lurquin, Christophe ; Courtoy, Pierre J. ; van der Bruggen, Pierre. A galectin-3 ligand corrects the impaired function of human CD4 and CD8 tumor-infiltrating lymphocytes and favors tumor rejection in mice. In: Cancer Research, Vol. 70, no. 19, p. 7476-7488 (2010). doi:10.1158/0008-5472.CAN-10-0761.
2010
Kholmanskikh, Olga ; van Baren, Nicolas ; Brasseur, Francis ; Ottaviani, Sabrina ; Vanacker, Julie ; Arts, Nathalie ; van der Bruggen, Pierre ; Coulie, Pierre G. ; De Plaen, Etienne. Interleukins 1 alpha and 1 beta secreted by some melanoma cell lines strongly reduce expression of MITF-M and melanocyte differentiation antigens. In: International Journal of Cancer, Vol. 127, no. 7, p. 1625-36 (2010). doi:10.1002/ijc.25182.
2009
Stockis, Julie ; Fink, Wolfram ; François, Violaine ; Connerotte, Thierry ; De Smet, Charles ; Knoops, Laurent ; van der Bruggen, Pierre ; Boon, Thierry ; Coulie, Pierre G. ; Lucas, Sophie. Comparison of stable human Treg and Th clones by transcriptional profiling.. In: European Journal of Immunology, Vol. 39, no. 3, p. 869-882 (2009). doi:10.1002/eji.200838807.
2009
Baurain, Jean-François ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Coulie, Pierre G. ; van Baren, Nicolas. Immunothérapie du cancer par vaccination contre des antigènes tumoraux. Notre expérience dans le mélanome. In: Oncologie, Vol. 3, p. 25-36 (2009).
2009
Bonehill, Aude ; Van Nuffel, An M T ; Corthals, Jurgen ; Tuyaerts, Sandra ; Heirman, Carlo ; François, Violaine ; Colau, Didier ; van der Bruggen, Pierre ; Neyns, Bart ; Thielemans, Kris. Single-Step Antigen Loading and Activation of Dendritic Cells by mRNA Electroporation for the Purpose of Therapeutic Vaccination in Melanoma Patients.. In: Clinical Cancer Research, Vol. 15, no. 10, p. 3366-75 (2009). doi:10.1158/1078-0432.CCR-08-2982.
2009
François, Violaine ; Ottaviani, Sabrina ; Renkvist, Nicolina ; Stockis, Julie ; Schuler, Gerold ; Thielemans, Kris ; Colau, Didier ; Marchand, Marie ; Boon, Thierry ; Lucas, Sophie ; van der Bruggen, Pierre. The CD4+ T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells.. In: Cancer Research, Vol. 69, no. 10, p. 4335-45 (2009). doi:10.1158/0008-5472.CAN-08-3726.
2008
Graham, Simon P ; Pellé, Roger ; Yamage, Mat ; Mwangi, Duncan M ; Honda, Yoshikazu ; Mwakubambanya, Ramadhan S ; de Villiers, Etienne P ; Abuya, Evelyne ; Awino, Elias ; Gachanja, James ; Mbwika, Ferdinand ; Muthiani, Anthony M ; Muriuki, Cecelia ; Nyanjui, John K ; Onono, Fredrick O ; Osaso, Julius ; Riitho, Victor ; Saya, Rosemary M ; Ellis, Shirley A ; McKeever, Declan J ; MacHugh, Niall D ; Gilbert, Sarah C ; Audonnet, Jean-Christophe ; Morrison, W Ivan ; van der Bruggen, Pierre ; Taracha, Evans L N. Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva.. In: Infection and Immunity, Vol. 76, no.2, p. 685-94 (2008). doi:10.1128/IAI.01244-07.
2008
Baurain, Jean-François ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Coulie, Pierre G. ; van Baren, Nicolas. Principes généraux et premiers essais cliniques de vaccination thérapeutique contre le cancer. In: Bulletin du Cancer, Vol. 95, no. 3, p. 327-335 (2008). doi:10.1684/bdc.2008.0588.
2008
Demotte, Nathalie ; Stroobant, Vincent ; Courtoy, Pierre J. ; Van Der Smissen, Patrick ; Colau, Didier ; Luescher, Immanuel F ; Hivroz, Claire ; Nicaise, Julie ; Squifflet, Jean-Luc ; Mourad, Michel ; Godelaine, Danièle ; Boon, Thierry ; van der Bruggen, Pierre. Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes. In: Immunity, Vol. 28, no. 3, p. 414-424 (2008). doi:10.1016/j.immuni.2008.01.011.
2008
Carrasco, Javier ; Van Pel, Aline ; Neyns, Bart ; Lethé, Bernard ; Brasseur, Francis ; Renkvist, Nicolina ; van der Bruggen, Pierre ; van Baren, Nicolas ; Paulus, Robert ; Thielemans, Kris ; Boon, Thierry ; Godelaine, Danièle. Vaccination of a Melanoma Patient with Mature Dendritic Cells Pulsed with MAGE-3 Peptides Triggers the Activity of Nonvaccine Anti-Tumor Cells.. In: Journal of Immunology, Vol. 180, no. 5, p. 3585-93 (2008). doi:10.4049/jimmunol.180.5.3585.
2007
Graham, Simon P ; Honda, Yoshikazu ; Pellé, Roger ; Mwangi, Duncan M ; Glew, E Jane ; de Villiers, Etienne P ; Shah, Trushar ; Bishop, Richard ; van der Bruggen, Pierre ; Nene, Vishvanath ; Taracha, Evans L N. A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology.. In: Immunome Research, Vol. 3, p. 2 (2007). doi:10.1186/1745-7580-3-2.
2007
Wang, Xiao-Fei ; Cohen, William M. ; Castelli, Florence A. ; Almunia, Christine ; Lethe, Bernard ; Pouvelle-Moratille, Sandra ; Munier, Gaetan ; Charron, Dominique ; Menez, Andre ; Zarour, Hassan M. ; van der Bruggen, Pierre ; Busson, Marc ; Maillere, Bernard. Selective identification of HLA-DP4 binding T cell epitopes encoded by the MAGE-A gene family. In: Cancer Immunology Immunotherapy, Vol. 56, no. 6, p. 807-818 (2007). doi:10.1007/s00262-006-0230-y.
2007
Erfurt, Cornelia ; Sun, Zhaojun ; Haendle, Ina ; Schuler-Thurner, Beatrice ; Heirman, Carlo ; Thielemans, Kris ; van der Bruggen, Pierre ; Schuler, Gerold ; Schultz, Erwin S. Tumor-reactive CD4+ T cell responses to the melanoma-associated chondroitin sulphate proteoglycan in melanoma patients and healthy individuals in the absence of autoimmunity.. In: Journal of Immunology, Vol. 178, no. 12, p. 7703-7709 (2007). doi:10.4049/jimmunol.178.12.7703.
2006
Sun, Zhaojun ; LETHE, Bernard ; Zhang, Yi ; Russo, Vincenzo ; Colau, Didier ; Stroobant, Vincent ; Boon-Falleur, Thierry ; van der Bruggen, Pierre. A new LAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-A68 tumors.. In: Cancer Immunology, Immunotherapy : other biological response modifications, Vol. 55, no. 6, p. 644-652 (2006). doi:10.1007/s00262-005-0066-x.
2006
Ottaviani, Sabrina ; Colau, Didier ; van der Bruggen, Pierre. A new MAGE-4 antigenic peptide recognized by cytolytic T lymphocytes on HLA-A24 carcinoma cells.. In: Cancer Immunology Immunotherapy, Vol. 55, no. 7, p. 867-872 (2006). doi:10.1007/s00262-005-0053-2.
2006
Carrasco Bertrand, Javier ; Godelaine, Danièle ; Boon, Thierry ; Van Pel, Aline ; van der Bruggen, Pierre. CD45RA on human CD8 T cells is sensitive to the time elapsed since the last antigenic stimulation.. In: Blood, Vol. 108, no. 9, p. 2897-2905 (2006). doi:10.1182/blood-2005-11-007237.
2006
Boon, Thierry ; Coulie, Pierre G. ; Van den Eynde, Benoît ; van der Bruggen, Pierre. Human T cell responses against melanoma. In: Annual Review of Immunology, Vol. 24, p. 175-208 (2006). doi:10.1146/annurev.immunol.24.021605.090733.
2006
van der Bruggen, Pierre ; Van den Eynde, Benoît. Processing and presentation of tumor antigens and vaccination strategies. In: Current Opinion in Immunology, Vol. 18, no. 1, p. 98-104 (2006). doi:10.1016/j.coi.2005.11.013.
2006
Graham, Simon P. ; Pellé, Roger ; Honda, Yoshikazu ; Mwangi, Duncan ; Tonukari, Nyerhovwo ; Yamage, Mat ; Glew, Jane E. ; de Villiers, Etienne P. ; Shah, Trushar ; Bishop, Richard ; Abuya, Eevelyne ; Awino, Elias ; Gachanja, James ; Luyai, Aanthony E. ; Mbwika, Ferdinand ; Muthiani, Anthony M. ; Ndegwa, David M. ; Njahira, Moses ; Nyanjui, John K. ; Onono, Frédrick O. ; Osao, Julius ; Saya, Rosemary M. ; Wildmann, Claude ; Fraser, Claire M. ; Maudlin, Ian ; Gardner, Malcolm J. ; Morzaria, Subhash P. ; Loosmore, Sheena ; Gilbert, Sarah C. ; Audonnet, Jean-Christophe ; van der Bruggen, Pierre ; Nene, Vishvanath ; Taracha, Evans L. N.. Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes. In: Proceedings of the National academy of sciences of the United States of America, Vol. 103, no. 9, p. 3286-3291 (2006). doi:10.1073/pnas.0511273103.
2005
Ottaviani, Sabrina ; Zhang, Yi ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-1 antigenic peptide recognized by human cytolytic T lymphocytes on HLA-A2 tumor cells.. In: Cancer Immunology, Immunotherapy : other biological response modifications, Vol. 54, no. 12, p. 1214-1220 (2005). doi:10.1007/s00262-005-0705-2.
2005
van de Corput, L ; Chaux, P. ; van der Meijden, ED ; De Plaen, Etienne ; Falkenburg, JHF ; van der Bruggen, Pierre. A novel approach to identify antigens recognized by CD4 T cells using complement-opsonized bacteria expressing a cDNA library. In: Leukemia, Vol. 19, no. 2, p. 279-285 (2005). doi:10.1038/sj.leu.2403583.
2005
Zhang, Yi ; Renkvist, Nicolina ; Sun, Zhaojun ; Schuler-Thurner, B. ; Glaichenhaus, N ; Schuler, G. ; Boon, Thierry ; van der Bruggen, Pierre ; Colau, Didier. A polyclonal anti-vaccine CD4 T cell response detected with HLA-DP4 multimers in a melanoma patient vaccinated with MAGE-3.DP4-peptide-pulsed dendritic cells. In: European Journal of Immunology, Vol. 35, no. 4, p. 1066-1075 (2005). doi:10.1002/eji.200425847.
2005
Michiels, A. ; Tuyaerts, Sandra ; Bonehill, A ; Corthals, J ; Breckpot, K ; Heirman, C. ; Van Meirvenne, S ; Dullaers, M ; Allard, S ; Brasseur, Francis ; van der Bruggen, Pierre ; Thielemans, K.. Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines. In: Gene Therapy, Vol. 12, no. 9, p. 772-782 (2005). doi:10.1038/sj.gt.3302471.
2005
Grunau, Christoph ; Sanchez, Cecilia ; Ehrlich, Melanie ; van der Bruggen, Pierre ; Hindermann, Winfried ; Rodriguez, Carmen ; Krieger, Sophie ; Dubeau, Louis ; Fiala, Emerich ; De Sario, Albertina. Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer.. In: Genes, Chromosomes & Cancer, Vol. 43, no. 1, p. 11-24 (2005). doi:10.1002/gcc.20155.
2005
Zhang, Yi ; Sun, Zhaojun ; Nicolay, Hugues ; Meyer, Ralf G. ; Renkvist, Nicolina ; Stroobant, Vincent ; Corthals, Jurgen ; Carrasco Bertrand, Javier ; Eggermont, Alexander ; Marchand, Marie ; Thielemans, Kris ; Wolfel, Thomas ; Boon, Thierry ; van der Bruggen, Pierre. Monitoring of anti-vaccine CD4 T cell frequencies in melanoma patients vaccinated with a MAGE-3 protein. In: Journal of Immunology, Vol. 174, no. 4, p. 2404-2411 (2005). doi:10.4049/jimmunol.174.4.2404.
2005
Kruit, WHJ ; Van Ojik, Heidi H. ; Brichard, Vincent G. ; Escudier, B ; Dorval, T ; Dréno, B. ; Patel, P ; van Baren, Nicolas ; Avril, Marie-Françoise ; Piperno, S ; Khammari, A ; Stas, M. ; Ritter, G. ; LETHE, Bernard ; GODELAINE, Danièle ; Brasseur, Francis ; Zhang, Yi ; van der Bruggen, Pierre ; Boon, Thierry ; Eggermont, AMM ; Marchand, Marie. Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma. In: International Journal of Cancer, Vol. 117, no. 4, p. 596-604 (2005). doi:10.1002/ijc.21264.
2005
van Baren, Nicolas ; Bonnet, Marie-Claude ; Dréno, B. ; Khammari, A ; Dorval, T ; Piperno-Neumann, S ; Lienard, D. ; Speiser, David ; Marchand, Marie ; Brichard, Vincent G. ; Escudier, B ; Negrier, S ; Dietrich, PY ; Maraninchi, D. ; Osanto, S ; Meyer, RG ; Ritter, G. ; Moingeon, P ; Tartaglia, J ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Boon, Thierry. Tumoral and immunologic response after vaccination of melanoma patients with an ALVAC virus encoding MAGE antigens recognized by T cells. In: Journal of Clinical Oncology, Vol. 23, no. 35, p. 9008-9021 (2005). doi:10.1200/JCO.2005.08.375.
2004
Vigneron, Nathalie ; Stroobant, Vincent ; Chapiro, Jacques ; Ooms, Annie ; Degiovanni, Gérard ; Morel, Sandra ; van der Bruggen, Pierre ; Boon, Thierry ; Van den Eynde, Benoît. An antigenic peptide produced by peptide splicing in the proteasome. In: Science, Vol. 304, no. 5670, p. 587-590 (2004). doi:10.1126/science.1095522.
2004
Lonchay, Christophe ; van der Bruggen, Pierre ; Connerotte, Thierry ; Hanagiri, Takeshi ; Coulie, Pierre G. ; Colau, Didier ; Lucas, Sophie ; Van Pel, Aline ; Thielemans, Kris ; van Baren, Nicolas ; Boon, Thierry. Correlation between tumor regression and T cell responses in melanoma patients vaccinated with a MAGE antigen.. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101 Suppl 2, p. 14631-8 (2004). doi:10.1073/pnas.0405743101.
2004
Schultz, Erwin S ; Schuler-Thurner, Beatrice ; Stroobant, Vincent ; Jenne, Lars ; Berger, Thomas G ; Thielemanns, Kris ; van der Bruggen, Pierre ; Schuler, Gerold. Functional analysis of tumor-specific Th cell responses detected in melanoma patients after dendritic cell-based immunotherapy.. In: Journal of Immunology, Vol. 172, no. 2, p. 1304-1310 (2004). doi:10.4049/jimmunol.172.2.1304.
2004
Corbiere, Véronique ; Nicolay, H ; Russo, V ; Stroobant, Vincent ; Brichard, Vincent ; Boon, Thierry ; van der Bruggen, Pierre. Identification of a MAGE-1 peptide recognized by cytolytic T lymphocytes on HLA-B*5701 tumors. In: Tissue Antigens, Vol. 63, no. 5, p. 453-7 (2004). doi:10.1111/j.0001-2815.2004.00203.x.
2004
Breckpot, Karine ; Heirman, Carlo ; De Greef, Catherine ; van der Bruggen, Pierre ; Thielemans, Kris. Identification of new antigenic peptide presented by HLA-Cw7 and encoded by several MAGE genes using dendritic cells transduced with lentiviruses.. In: Journal of Immunology, Vol. 172, no. 4, p. 2232-2237 (2004). doi:10.4049/jimmunol.172.4.2232.
2004
Bonehill, Aude ; Heirman, Carlo ; Tuyaerts, Sandra ; Michiels, Annelies ; Breckpot, Karine ; Brasseur, Francis ; Zhang, Yi ; van der Bruggen, Pierre ; Thielemans, Kris. Messenger RNA-electroporated dendritic cells presenting MAGE-A3 simultaneously in HLA class I and class II molecules.. In: Journal of Immunology, Vol. 172, no. 11, p. 6649-6657 (2004). doi:10.4049/jimmunol.172.11.6649.
2004
Dullaers, M ; Breckpot, K ; Van Meirvenne, S ; Bonehill, A ; Tuyaerts, Sandra ; Michiels, A. ; Straetman, L ; Heirman, C. ; De Greef, C ; van der Bruggen, Pierre ; Thielemans, K.. Side-by-side comparison of lentivirally transduced and mRNA-electroporated dendritic cells: Implications for cancer immunotherapy protocols. In: Molecular Therapy, Vol. 10, no. 4, p. 768-779 (2004). doi:10.1016/j.ymthe.2004.07.017.
2003
Zhang, Y. ; Chaux, P ; Stroobant, Vincent ; Eggermont, AMM ; Corthals, J ; Maillere, B ; Thielemans, K. ; Marchand, Marie ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-3 peptide presented by HLA-DR1 to CD4(+) T cells that were isolated from a melanoma patient vaccinated with a MAGE-3 protein. In: Journal of Immunology, Vol. 171, no. 1, p. 219-225 (2003). doi:10.4049/jimmunol.171.1.219.
2003
Vantomme, Valérie ; Boël, Pascale ; Boon, Thierry ; De Plaen, Etienne ; van der Bruggen, Pierre. A new tumor-specific antigenic peptide encoded by MAGE-6 is presented to cytolytic T lymphocytes by HLA-Cw16.. In: Cancer Immunity, Vol. 3, p. 17 (2003).
2003
Jacquemin, Marc ; Vantomme, Valérie ; Buhot, Cécile ; Lavend'homme, Renaud ; Burny, Wivine ; Demotte, Nathalie ; Chaux, Pascal ; Peerlinck, Kathelijne ; Vermylen, Jos ; Maillere, Bernard ; van der Bruggen, Pierre ; Saint-Remy, Jean-Marie. CD4+ T-cell clones specific for wild-type factor VIII: a molecular mechanism responsible for a higher incidence of inhibitor formation in mild/moderate hemophilia A.. In: Blood, Vol. 101, no.4, p. 1351-8 (2003). doi:10.1182/blood-2002-05-1369.
2003
Bonehill, A ; Heirman, C. ; Tuyaerts, Sandra ; Michiels, A. ; Zhang, Y. ; van der Bruggen, Pierre ; Thielemans, K.. Efficient presentation of known HLA class II-restricted MAGE-A3 epitopes by dendritic cells electroporated with messenger RNA encoding an invariant chain with genetic exchange of class II-associated invariant chain peptide. In: Cancer Research, Vol. 63, no. 17, p. 5587-5594 (2003).
2003
Breckpot, K ; Dullaers, M ; Bonehill, A ; Van Meirvenne, S ; Heirman, C. ; De Greef, C ; van der Bruggen, Pierre ; Thielemans, K.. Lentivirally transduced dendritic cells as a tool for cancer immunotherapy. In: Journal of Gene Medicine, Vol. 5, no. 8, p. 654-667 (2003). doi:10.1002/jgm.400.
2003
Kobayashi, T. ; Lonchay, Christophe ; Colau, Didier ; Demotte, Nathalie ; Boon, Thierry ; van der Bruggen, Pierre. New MAGE-4 antigenic peptide recognized by cytolytic T lymphocytes on HLA-A1 tumor cells. In: Tissue Antigens, Vol. 62, no. 5, p. 426-432 (2003). doi:10.1034/j.1399-0039.2003.00123.x.
2003
Coulie, Pierre G. ; van der Bruggen, Pierre. T-cell responses of vaccinated cancer patients.. In: Current Opinion in Immunology, Vol. 15, no. 2, p. 131-137 (2003). doi:10.1016/S0952-7915(03)00009-8.
2002
Bilsborough, Janine ; Panichelli, C ; Duffour, MT ; Warnier, G. ; Lurquin, C. ; Schultz, ES ; Thielemans, K. ; Corthals, J ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-3 peptide presented by HLA-B44 is also recognized by cytolytic T lymphocytes on HLA-B18. In: Tissue Antigens, Vol. 60, no. 1, p. 16-24 (2002). doi:10.1034/j.1399-0039.2002.600103.x.
2002
Zhang, Y. ; Stroobant, Vincent ; Russo, V ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-A4 peptide presented by HLA-B37 is recognized on human tumors by cytolytic T lymphocytes.. In: Tissue antigens, Vol. 60, no. 5, p. 365-371 (2002). doi:10.1034/j.1399-0039.2002.600503.x.
2002
Demotte, Nathalie ; Colau, Didier ; Ottaviani, Sabrina ; Godelaine, Danièle ; Van Pel, Aline ; Boon-Falleur, Thierry ; van der Bruggen, Pierre. A reversible functional defect of CD8+ T lymphocytes involving loss of tetramer labeling. In: European Journal of Immunology, Vol. 32, no. 6, p. 1688-1697 (2002). doi:10.1002/1521-4141(200206)32:6<1688::AID-IMMU1688>3.0.CO;2-9.
2002
Ruault, Myriam ; van der Bruggen, Pierre ; Brun, Marie-Elisabeth ; Boyle, Shelagh ; Roizès, Gérard ; De Sario, Albertina. New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile.. In: European Journal of Human Genetics, Vol. 10, no. 12, p. 833-40 (2002). doi:10.1038/sj.ejhg.5200891.
2002
Schultz, Erwin S. ; Chapiro, Jacques ; Lurquin, Christophe ; Claverol, Stéphane ; Burlet-Schiltz, Odile ; Warnier, Guy ; Russo, Vincenzo ; Morel, Sandra ; Lévy, Frédéric ; Boon-Falleur, Thierry ; Van den Eynde, Benoît ; van der Bruggen, Pierre. The production of a new MAGE-3 peptide presented to cytolytic T lymphocytes by HLA-B40 requires the immunoproteasome. In: The Journal of Experimental Medicine, Vol. 195, no. 4, p. 391-399 (2002). doi:10.1084/jem.20011974.
2002
van der Bruggen, Pierre ; Zhang, Yi ; Chaux, Pascal ; Stroobant, Vincent ; Panichelli, Christophe ; Schultz, Erwin S ; Chapiro, Jacques ; Van den Eynde, Benoît ; Brasseur, Francis ; Boon, Thierry. Tumor-specific shared antigenic peptides recognized by human T cells. In: Immunological Reviews, Vol. 188, p. 51-64 (2002). doi:10.1034/j.1600-065X.2002.18806.x.
2002
Sauvonnet, Nathalie ; Lambermont, Isabelle ; van der Bruggen, Pierre ; Cornelis, Guy. YopH prevents monocyte chemoattractant protein 1 expression in macrophages and T-cell proliferation through inactivation of the phosphatidylinositol 3-kinase pathway.. In: Molecular microbiology, Vol. 45, no. 3, p. 805-15 (2002). doi:10.1046/j.1365-2958.2002.03053.x.
2001
Chaux, P ; Lethé, B ; Van Snick, Jacques ; Corthals, J ; Schultz, E S ; Cambiaso, Cesar ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-1 peptide recognized on HLA-DR15 by CD4(+) T cells.. In: European journal of immunology, Vol. 31, no. 6, p. 1910-6 (2001). doi:10.1002/1521-4141(200106)31:6<1910::AID-IMMU1910>3.0.CO;2-K.
2001
Schultz, ES ; Zhang, Y. ; Knowles, R ; Tine, J ; Traversari, C. ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-3 peptide recognized on HLA-B35 and HLA-A1 by cytolytic T lymphocytes. In: Tissue Antigens, Vol. 57, no. 2, p. 103-109 (2001). doi:10.1034/j.1399-0039.2001.057002103.x.
2001
You, ZY ; Hester, J ; Rollins, L ; Spagnoli, GC ; van der Bruggen, Pierre ; Chen, SY. A retrogen strategy for presentation of an intracellular tumor antigen as an exogenous antigen by dendritic cells induces potent antitumor T helper and CTL responses. In: Cancer Research, Vol. 61, no. 1, p. 197-205 (2001).
2000
Luiten, Rosalie ; van der Bruggen, Pierre. A MAGE-A1 peptide is recognized on HLA-B7 human tumors by cytolytic T lymphocytes. In: Tissue Antigens, Vol. 55, no. 2, p. 149-152 (2000). doi:10.1034/j.1399-0039.2000.550206.x.
2000
Luiten, Rosalie M ; Demotte, Nathalie ; Tine, John ; van der Bruggen, Pierre. A MAGE-A1 peptide presented to cytolytic T lymphocytes by both HLA-B35 and HLA-A1 molecules.. In: Tissue Antigens, Vol. 56, no. 1, p. 77-81 (2000). doi:10.1034/j.1399-0039.2000.560110.x.
2000
Schultz, Erwin S ; Lethé, Bernard ; Cambiaso, Cesar L ; Van Snick, Jacques ; Chaux, Pascal ; Corthals, Jurgen ; Heirman, Carlo ; Thielemans, Kris ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-A3 peptide presented by HLA-DP4 is recognized on tumor cells by CD4+ cytolytic T lymphocytes.. In: Cancer Research, Vol. 60, no. 22, p. 6272-5 (2000).
2000
Mandruzzato, Susanna ; Stroobant, Vincent ; Demotte, Nathalie ; van der Bruggen, Pierre. A human CTL recognizes a caspase-8-derived peptide on autologous HLA-B*3503 molecules and two unrelated peptides on allogeneic HLA-B*3501 molecules. In: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, no. 8, p. 4130-4 (2000). doi:10.4049/jimmunol.164.8.4130.
1999
Duffour, Marie-Thérèse ; Chaux, Pascal ; Lurquin, C.hristophe ; Cornelis, Guy ; Boon, Thierry ; van der Bruggen, Pierre. A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes. In: European Journal of Immunology, Vol. 29, no. 10, p. 3329-3337 (1999). doi:10.1002/(SICI)1521-4141(199910)29:10<3329::AID-IMMU3329>3.0.CO;2-7.
1999
Duffour, Marie-Thérèse ; Chaux, Pascal ; Lurquin, Christophe ; Cornelis, Guy ; Boon-Falleur, Thierry ; van der Bruggen, Pierre. A MAGE-A4 peptide presented by HLA-A2 is recognized by cytolytic T lymphocytes. In: European Journal of Immunology, Vol. 29, no.10, p. 3329-3337 (1999). doi:10.1002/(SICI)1521-4141(199910)29:10<3329::AID-IMMU3329>3.0.CO;2-7.
1999
Morel, Sandra ; Ooms, Annie ; Van Pel, Aline ; Wölfel, Thomas ; Brichard, Vincent G. ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Degiovanni, Gérard. A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes.. In: International Journal of Cancer, Vol. 83, no. 6, p. 755-9 (1999). doi:10.1002/(SICI)1097-0215(19991210)83:6<755::AID-IJC10>3.0.CO;2-S.
1999
De Backer, Olivier ; Arden, Karen C. ; Boretti, Mauro ; Vantomme, Valérie ; De Smet, Charles ; Czekay, Suzanne ; Viars, Carrie S. ; De Plaen, Etienne ; Brasseur, Francis ; Chomez, Patrick ; Van den Eynde, Benoît ; Boon-Falleur, Thierry ; van der Bruggen, Pierre. Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. In: Cancer Research, Vol. 59, no. 13, p. 3157-3165 (1999).
1999
Lake, D F ; Salgaller, M L ; van der Bruggen, Pierre ; Bernstein, R M ; Marchalonis, J J. Construction and binding analysis of recombinant single-chain TCR derived from tumor-infiltrating lymphocytes and a cytotoxic T lymphocyte clone directed against MAGE-1.. In: International Immunology, Vol. 11, no. 5, p. 745-51 (1999).
1999
Huang, Lan-Qing ; Brasseur, Francis ; Serrano, Alfonso ; De Plaen, Etienne ; van der Bruggen, Pierre ; Boon, Thierry ; Van Pel, Aline. Cytolytic T lymphocytes recognize an antigen encoded by MAGE-A10 on a human melanoma. In: Journal of Immunology, Vol. 162, no. 11, p. 6849-6854 (1999).
1999
Gileadi, U ; Gallimore, A ; van der Bruggen, Pierre ; Cerundolo, V. Effect of epitope flanking residues on the presentation of N-terminal cytotoxic T lymphocyte epitopes.. In: European Journal of Immunology, Vol. 29, no. 7, p. 2213-22 (1999). doi:10.1002/(SICI)1521-4141(199907)29:07<2213::AID-IMMU2213>3.0.CO;2-8.
1999
Chaux, Pascal ; Vantomme, Valérie ; Stroobant, Vincent ; Thielemans, Kris ; Corthals, Jurgen ; Luiten, Rosalie ; Eggermont, Alexander M.M. ; Boon, Thierry ; van der Bruggen, Pierre. Identification of MAGE-3 epitopes presented by HLA-DR molecules to CD4(+) T lymphocytes.. In: The Journal of Experimental Medicine, Vol. 189, no. 5, p. 767-777 (1999). doi:10.1084/jem.189.5.767.
1999
Chaux, Pascal ; Luiten, Rosalie ; Demotte, Nathalie ; Vantomme, Valérie ; Stroobant, Vincent ; Traversari, Catia ; Russo, Vincenzo ; Schultz, Erwin ; Cornelis, Guy R. ; Boon, Thierry ; van der Bruggen, Pierre. Identification of five MAGE-A1 epitopes recognized by cytolytic T lymphocytes obtained by in vitro stimulation with dendritic cells transduced with MAGE-A1. In: Journal of Immunology, Vol. 163, no. 5, p. 2928-2936 (1999).
1999
von Leoprechting, A ; van der Bruggen, Pierre ; Pahl, HL ; Aruffo, A ; Simon, JC. Stimulation of CD40 on immunogenic human malignant melanomas augments their cytotoxic T lymphocyte-mediated lysis and induces apoptosis. In: Cancer Research, Vol. 59, no. 6, p. 1287-1294 (1999).
1999
Marchand, Marie ; van Baren, Nicolas ; Weynants, Patrick ; Brichard, Vincent ; Dréno, Brigitte ; Tessier, Marie-Hélène ; Rankin, Elaine ; Parmiani, Giorgio ; Arienti, Flavio ; Humblet, Yves ; Bourlond, André ; Vanwijck, Romain ; Liénard, Danielle ; Beauduin, Marc ; Dietrich, Pierre-Yves ; Russo, Vincenzo ; Kerger, Joseph ; Masucci, Giuseppe ; Jäger, Elke ; De Greve, Jacques ; Atzpodien, Jens ; Brasseur, Francis ; Coulie, Pierre G. ; van der Bruggen, Pierre ; Boon, Thierry. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1.. In: International Journal of Cancer, Vol. 80, no. 2, p. 219-230 (1999). doi:10.1002/(SICI)1097-0215(19990118)80:2<219::AID-IJC10>3.0.CO;2-S.
1998
Tüting, T ; Wilson, C C ; Martin, D M ; Kasamon, Y L ; Rowles, J ; Ma, D I ; Slingluff, C L ; Wagner, S N ; van der Bruggen, Pierre ; Baar, J ; Lotze, M T ; Storkus, W J. Autologous human monocyte-derived dendritic cells genetically modified to express melanoma antigens elicit primary cytotoxic T cell responses in vitro: enhancement by cotransfection of genes encoding the Th1-biasing cytokines IL-12 and IFN-alpha.. In: Journal of Immunology, Vol. 160, no. 3, p. 1139-47 (1998).
1998
Dunbar, P R ; Ogg, G S ; Chen, J ; Rust, N ; van der Bruggen, Pierre ; Cerundolo, V. Direct isolation, phenotyping and cloning of low-frequency antigen-specific cytotoxic T lymphocytes from peripheral blood.. In: Current Biology, Vol. 8, no. 7, p. 413-6 (1998).
1998
Chaux, P ; Vantomme, V ; Coulie, Pierre G. ; Boon, Thierry ; van der Bruggen, Pierre. Estimation of the frequencies of anti-MAGE-3 cytolytic T-lymphocyte precursors in blood from individuals without cancer.. In: International Journal of Cancer, Vol. 77, no. 4, p. 538-42 (1998). doi:10.1002/(SICI)1097-0215(19980812)77:4<538::AID-IJC11>3.0.CO;2-2.
1998
Lee, R S ; Tartour, E ; van der Bruggen, Pierre ; Vantomme, V ; Joyeux, I ; Goud, B ; Fridman, W H ; Johannes, L. Major histocompatibility complex class I presentation of exogenous soluble tumor antigen fused to the B-fragment of Shiga toxin.. In: European Journal of Immunology, Vol. 28, no. 9, p. 2726-37 (1998). doi:10.1002/(SICI)1521-4141(199809)28:09<2726::AID-IMMU2726>3.0.CO;2-W.
1998
Van de Craen, M ; Van Loo, G ; Declercq, W ; Schotte, P ; Van den brande, I ; Mandruzzato, S ; van der Bruggen, Pierre ; Fiers, W. ; Vandenabeele, P.. Molecular cloning and identification of murine caspase-8. In: Journal of Molecular Biology, Vol. 284, no. 4, p. 1017-1026 (1998). doi:10.1006/jmbi.1998.2226.
1997
Mandruzzato, Susanna ; Brasseur, Francis ; Andry, Guy ; Boon-Falleur, Thierry ; Van Der Bruggen, Pierre. A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. In: The Journal of Experimental Medicine, Vol. 186, no. 5, p. 785-793 (1997). doi:10.1084/jem.186.5.785.
1997
Coulie, Pierre G. ; Van den Eynde, Benoît ; Van Der Bruggen, Pierre ; Van Pel, Aline ; Boon-Falleur, Thierry. Antigens recognized by T-lymphocytes on human tumours. In: Biochemical Society Transactions, Vol. 25, no. 2, p. 544-548 (1997). doi:10.1042/bst0250544.
1997
Fisch, P ; Meuer, E ; Pende, D ; Rothenfusser, S ; Viale, O ; Kock, S ; Ferrone, S ; Fradelizi, D ; Klein, G. ; Moretta, L ; Rammensee, HG. ; Boon, Thierry ; Coulie, Pierre G. ; van der Bruggen, Pierre. Control of B cell lymphoma recognition via natural killer inhibitory receptors implies a role for human V gamma/V delta 2 T cells in tumor immunity. In: European Journal of Immunology, Vol. 27, no. 12, p. 3368-79 (1997). doi:10.1002/eji.1830271236.
1997
Fleischhauer, K ; Tanzarella, S ; Russo, V ; Sensi, M L ; van der Bruggen, Pierre ; Bordignon, C ; Traversari, C. Functional heterogeneity of HLA-A*02 subtypes revealed by presentation of a MAGE-3-encoded peptide to cytotoxic T cell clones.. In: Journal of Immunology, Vol. 159, no. 5, p. 2513-21 (1997).
1997
Traversari, C ; Meazza, R ; Coppolecchia, M ; Basso, S ; Verrecchia, A ; van der Bruggen, Pierre ; Ardizzoni, A ; Gaggero, A ; Ferrini, S. IFN-gamma gene transfer restores HLA-class I expression and MAGE-3 antigen presentation to CTL in HLA-deficient small cell lung cancer.. In: Gene Therapy, Vol. 4, no. 10, p. 1029-35 (1997). doi:10.1038/sj.gt.3300489.
1997
Visseren, M J ; van der Burg, S H ; van der Voort, E I ; Brandt, R M ; Schrier, P I ; van der Bruggen, Pierre ; Boon, T ; Melief, C J ; Kast, W M. Identification of HLA-A*0201-restricted CTL epitopes encoded by the tumor-specific MAGE-2 gene product.. In: International Journal of Cancer, Vol. 73, no. 1, p. 125-30 (1997).
1997
De Plaen, Etienne ; Lurquin, Christophe ; Lethé, Bernard ; Van Der Bruggen, Pierre ; Brichard, Vincent ; Renauld, Jean-Christophe ; Coulie, Pierre G. ; Van Pel, Aline ; Boon-Falleur, Thierry. Identification of genes coding for tumor antigens recognized by cytolytic T lymphocytes. In: Methods, Vol. 12, no. 2, p. 125-142 (1997). doi:10.1006/meth.1997.0462.
1997
Lethé, Bernard ; Van Der Bruggen, Pierre ; Brasseur, Francis ; Boon-Falleur, Thierry. MAGE-1 expression threshold for the lysis of melanoma cell lines by a specific cytotoxic T lymphocyte. In: Melanoma Research : a journal for basic, translational and clinical research in melanoma, Vol. 7, no. Suppl 2, p. S83-S88 (1997).
1997
Lecrenier, N ; van der Bruggen, Pierre ; Foury, Françoise. Mitochondrial DNA polymerases from yeast to man: a new family of polymerases.. In: Gene, Vol. 185, no. 1, p. 147-52 (1997). doi:10.1016/S0378-1119(96)00663-4.
1997
Van den Eynde, Benoît ; Van Der Bruggen, Pierre. T cell defined tumor antigens. In: Current Opinion in Immunology, Vol. 9, no. 5, p. 684-693 (1997). doi:10.1016/S0952-7915(97)80050-7.
1996
Herman, Jean ; van der Bruggen, Pierre ; Luescher, I F ; Mandruzzato, S ; Romero, P. ; Thonnard, J. ; Fleischhauer, K ; Boon, Thierry ; Coulie, Pierre G.. A peptide encoded by human gene MAGE-3 and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3.. In: Immunogenetics, Vol. 43, no. 6, p. 377-83 (1996). doi:10.1007/BF02199806.
1996
Farina, C. ; van der Bruggen, Pierre ; Boël, P. ; Parmiani, G. ; Sensi, M.. Conserved TCR usage by HLA-Cw*1601-restricted T cell clones recognizing melanoma antigens. In: International Immunology, Vol. 8, no. 9, p. 1463-1466 (1996). doi:10.1093/intimm/8.9.1463.
1996
Boon, Thierry ; van der Bruggen, Pierre. Human tumor antigens recognized by T lymphocytes. In: The Journal of Experimental Medicine, Vol. 183, no. 3, p. 725-729 (1996). doi:10.1084/jem.183.3.725.
1996
Viale, O ; van der Bruggen, Pierre ; Meuer, E ; Kunzmann, R ; Kohler, H ; Mertelsmann, R ; Boon, Thierry ; Fisch, P. Recognition by human V gamma 9/V delta 2 T cells of melanoma cells upon fusion with Daudi cells. In: Immunogenetics, Vol. 45, no. 1, p. 27-34 (1996). doi:10.1007/s002510050163.
1995
Boël, P. ; Wildmann, C. ; Sensi, ML. ; Brasseur, R. ; Renauld, Jean-Christophe ; Coulie, Pierre G. ; Boon, Thierry ; van der Bruggen, Pierre. Bage - a New Gene Encoding An Antigen Recognized On Human Melanomas By Cytolytic T-lymphocytes. In: Immunity, Vol. 2, no. 2, p. 167-175 (1995). doi:10.1016/S1074-7613(95)80053-0.
1995
Van Pel, Aline ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Brichard, Vincent G. ; Lethe, Bernard ; Van den Eynde, Benoît ; Uyttenhove, Catherine ; Renauld, Jean-Christophe ; Boon, Thierry. Genes coding for tumor-antigens recognized by cytolytic T-lymphocytes. In: Immunological Reviews, Vol. 145, p. 229-250 (1995). doi:10.1111/j.1600-065X.1995.tb00084.x.
1994
van der Bruggen, Pierre ; Bastin, Judy ; Gajewski, Thomas ; Coulie, Pierre G. ; Boël, Pascale ; De Smet, Charles ; Traversari, Catia ; Townsend, Alain ; Boon-Falleur, Thierry. A peptide encoded by human gene MAGE-3 and presented by HLA-A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE-3. In: European Journal of Immunology, Vol. 24, no. 12, p. 3038-3043 (1994). doi:10.1002/eji.1830241218.
1994
van der Bruggen, Pierre ; Szikora, Jean-Pierre ; Boël, Pascale ; Wildmann, Claude ; Somville, Michel ; Sensi, Marialuisa ; Boon-Falleur, Thierry. Autologous cytolytic T lymphocytes recognize a MAGE-1 nonapeptide on melanomas expressing HLA-Cw*1601. In: European Journal of Immunology, Vol. 24, no. 9, p. 2134-2140 (1994). doi:10.1002/eji.1830240930.
1994
Gaugler, Béatrice ; Van den Eynde, Benoit ; van der Bruggen, Pierre ; Romero, Pedro ; Gaforio, Jose Juan ; De Plaen, Etienne ; Lethé, Bernard ; Brasseur, Francis ; Boon-Falleur, Thierry. Human gene Mage-3 codes for an antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. In: The Journal of Experimental Medicine, Vol. 179, no. 3, p. 921-930 (1994). doi:10.1084/jem.179.3.921.
1994
Chen, Yao-Tseng ; Stockert, Elisabeth ; Chen, Yachi ; Garin-Chesa, Pilar ; Rettig, Wolfgang J. ; van der Bruggen, Pierre ; Boon-Falleur, Thierry ; Old, Lloyd J.. Identification of the Mage-1 Gene-product By Monoclonal and Polyclonal Antibodies. In: Proceedings of the National academy of sciences of the United States of America, Vol. 91, no. 3, p. 1004-1008 (1994). doi:10.1073/pnas.91.3.1004.
1994
De Smet, Charles ; Lurquin, C. ; van der Bruggen, Pierre ; De Plaen, Etienne ; Brasseur, Francis ; Boon-Falleur, Thierry. Sequence and Expression Pattern of the Human Mage2 Gene. In: Immunogenetics, Vol. 39, no. 2, p. 121-129 (1994). doi:10.1007/BF00188615.
1994
De Plaen, Etienne ; Arden, Karen ; Traversari, Catia ; Gaforio, José Juan ; Szikora, Jean-Pierre ; De Smet, Charles ; Brasseur, Francis ; van der Bruggen, Pierre ; Lethé, Bernard ; Lurquin, Christophe ; Brasseur, Robert ; Chomez, Patrick ; De Backer, Olivier ; Cavenee, Webster ; Boon-Falleur, Thierry. Structure, Chromosomal Localization, and Expression of 12 Genes of the Mage Family. In: Immunogenetics, Vol. 40, no. 5, p. 360-369 (1994). doi:10.1007/BF01246677.
1994
van der Bruggen, Pierre. The Long-standing Quest for Tumor Rejection Antigens. In: Clinical Immunology and Immunopathology, Vol. 71, no. 3, p. 248-252 (1994). doi:10.1006/clin.1994.1080.
1994
Amar-Costesec, Alain ; Godelaine, Danièle ; Stockert, Elisabeth ; Van Der Bruggen, Pierre ; Beaufay, Henri ; Chen, Yao-Tseng. The tumor protein MAGE-1 is located in the cytosol of human melanoma cells. In: Biochemical and Biophysical Research Communications, Vol. 204, no. 2, p. 710-715 (1994). doi:10.1006/bbrc.1994.2517.
1994
Boon-Falleur, Thierry ; Cerottini, Jean-Charles ; Van den Eynde, Benoît ; van der Bruggen, Pierre ; Van Pel, Aline. Tumor antigens recognized by T lymphocytes. In: Annual Review of Immunology, Vol. 12, p. 337-365 (1994). doi:10.1146/annurev.iy.12.040194.002005.
1993
Marchand, Marie ; Brasseur, Francis ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Boon, Thierry. Perspectives for immunization of HLA-A1 patients carrying a malignant-melanoma expressing gene MAGE-1. In: Dermatology, Vol. 186, no. 4, p. 278-280 (1993). doi:10.1159/000247375.
1992
Traversari, C. ; van der Bruggen, Pierre ; Luescher, IF. ; Lurquin, C. ; Chomez, P. ; Van Pel, Aline ; De Plaen, Etienne ; Amarcostesec, A. ; Boon, Thierry. A Nonapeptide Encoded By Human Gene Mage-1 Is Recognized On Hla-a1 By Cytolytic Lymphocytes-t Directed Against Tumor Antigen-mz2-e. In: The Journal of Experimental Medicine, Vol. 176, no. 5, p. 1453-1457 (1992). doi:10.1084/jem.176.5.1453.
1992
Boon, Thierry ; De Plaen, Etienne ; Lurquin, Christophe ; Van den Eynde, Benoît ; van der Bruggen, Pierre ; Traversari, Catia ; Amar-Costesec, Alain ; Van Pel, Aline. Identification of tumor rejection antigens recognized by lymphocytes-T. In: Cancer Surveys, Vol. 13, p. 23-37 (1992).
1992
van der Bruggen, Pierre ; Van den Eynde, Benoît. Molecular definition of tumor-antigens recognized by T lymphocytes. In: Current Opinion in Immunology, Vol. 4, no. 5, p. 608-612 (1992). doi:10.1016/0952-7915(92)90035-D.
1992
Traversari, C. ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Hainaut, Philippe ; Lemoine, Carine ; Ohta, Nobuyoshi ; Old, Lloyd ; Boon, Thierry. Transfection and expression of a gene coding for a human-melanoma antigen recognized by autologous cytolytic T lymphocytes. In: Immunogenetics, Vol. 35, no. 3, p. 145-152 (1992). doi:10.1007/BF00185107.
1991
van der Bruggen, Pierre ; Traversari, Catia ; Chomez, Patrick ; Lurquin, Christophe ; De Plaen, Etienne ; Van den Eynde, Benoît ; Knuth, Alex ; Boon, Thierry. A gene encoding an antigen recognized by cytolytic lymphocytes-T on a human-melanoma. In: Science, Vol. 254, no. 5038, p. 1643-1647 (1991). doi:10.1126/science.1840703.
1990
van der Bruggen, Pierre ; Grégoire, D. ; Maraite, Henri. Temperature-induced Alterations in the Expression of Susceptibility of Cassava To Colletotrichum-gloeosporioides F Sp Manihotis. In: Journal of Phytopathology, Vol. 130, no. 1, p. 46-58 (1990).
1989
Van den Eynde, Benoît ; Hainaut, Philippe ; Hérin, Michel ; Knuth, Alex ; Lemoine, Carine ; Weynants, Patrick ; Boon, Thierry ; Fauchet, Renée ; van der Bruggen, Pierre. Presence on a human melanoma of multiple antigens recognized by autologous CTL.. In: International Journal of Cancer, Vol. 44, no. 4, p. 634-640 (1989). doi:10.1002/ijc.2910440413.
2013
Pang, Ken C. ; Van den Eynde, Benoît ; van der Bruggen, Pierre ; Chen, Weisan. Tumour antigens recognised by T lymphocytes. In: eLS 2013, John Wiley & Sons Ltd: Chichester, 2013. doi:10.1002/9780470015902.a0001431.pub3.
2012
Demotte, Nathalie ; Antonopoulos, Aristotelis ; Baurain, Jean-François ; Wieers, Grégoire ; van Baren, Nicolas ; van der Bruggen, Pierre. Improving the clinical efficacy of cancer vaccines by targeting immune suppression in human tumors. In: Klyosov A.A. and Traber P.G., Galectins and Disease Implications for Targeted Therapeutics. Proceedings of the First Symposium on Galectin-Related Therapeutics (ACS Symposium Series; 1115), American Chemical Society: (United States) Washington, DC, 2012, 267-288. 978-0-8412-2880-1. doi:10.1021/bk-2012-1115.ch016.
2001
Boon-Falleur, Thierry ; Coulie, Pierre G. ; Van der Bruggen, Pierre ; van Baren, Nicolas. T-Lymphocyte Responses, 2001.
2000
van der Bruggen, Pierre. Human tumor antigens recognized by cytolytic T lymphocytes: Towards vaccination. In: Roopenian D. and Simpson E., Minor Histocompatibility Antigens: From the Laboratory to the Clinic, Landes Bioscience: Georgetown, TX, 2000, 171-182. 1570595992.
2000
Boon-Falleur, Thierry ; Coulie, Pierre G. ; van der Bruggen, Pierre ; van Baren, Nicolas. Immunologic Basis of cancer: T lymphocyte responses. Part I - Section 2.. In: Abeloff Md, Martin D ; Armitage Md, James O ; Lichter Md, Allen S ; Niederhuber Md, John E, Clinical Oncology, 2nd edition, Churchill Linvingstone: New York, 2000, p. 158-173. 9780443075452.
1999
van der Bruggen, Pierre ; Chaux, Pascal ; Mandruzzato, Susanna ; Van den Eynde, Benoît ; Coulie, Pierre G. ; Marchand, Marie ; Boon, Thierry. Towards vaccination with defined tumor antigens ?. In: N.G. Abraham ; A. Tabilio ; M. Martelli ; S. Asano ; A. Donfrancesco (eds.), Molecular Biology of Hematopoiesis. (Molecular Biology of Hematopoiesis.; 6), Kluwer Academic/plenum Publishers: New York, 1999, p. 159-174. 978-0-306-46136-1.
1997
Van den Eynde, Benoît ; Gaugler, B. ; Brändle, D. ; Guilloux, Y. ; Van Der Bruggen, Pierre ; Coulie, Pierre G. ; Brichard, Vincent ; Boon-Falleur, Thierry. Characterization of antigens recognized by T cells on human tumors. In: Eibl M., Huber C., Peter H.H., Wahn U., Symposium in Immunology VI, Springer-Verlag: Berlin/Heidelberg, 1997, 1-11. 9783540617556. doi:10.1007/978-3-642-60562-8_1.
1997
De Plaen, Etienne ; Lurquin, Christophe ; Brichard, Vincent ; Van Der Bruggen, Pierre ; Renauld, Jean-Christophe ; Coulie, Pierre G. ; Szikora, Jean-Pierre ; Wölfel, Thomas ; Van Pel, Aline ; Boon-Falleur, Thierry. Cloning of genes coding for antigens recognized by cytolytic T lymphocytes. In: Lefkovits I., Immunology Methods Manual: The Comprehensive Sourcebook of Techniques, Academic Press: London, 1997, 691-718. 978-0-1244-2710-5.
1994
van der Bruggen, Pierre ; Boël, P. ; Van den Eynde, Benoît ; Coulie, Pierre G. ; Brichard, Vincent ; Van Pel, Aline ; De Plaen, Etienne ; Brasseur, Francis ; Boon-Falleur, Thierry. Antigènes de rejet des tumeurs et immunothérapie du cancer. In: Chouaib S. and Mencia-Huerta J.-M., L'Immuno-intervention. De la biothérapie à la thérapie génique, MediaSciences: Paris, 1994, 79-95.
2011
Demotte, Nathalie ; Wieers, Grégoire ; Klyosov, Anatole ; van der Bruggen, Pierre. Is it possible to correct the impaired function of human tumor-infiltrating T lymphocytes?. Keystone Symposium (Lake Louise, AB, Canada, du 06/03/2011 au 11/03/2011).
2010
van der Bruggen, Pierre ; Demotte, Nathalie ; Wieers, Grégoire. Is it possible to correct the impaired function of human tumor-infiltrating T lymphocytes?. 25th Annual Meeting of the International Society for Biological Therapy of Cancer (Washington D.C., USA, du 02/10/2010 au 04/10/2010).
2009
Van den Eynde, Benoît ; van der Bruggen, Pierre. Invited lecture: Fighting tumoral immune resistance. Keystone Symposium (Snowbird, UT, USA, du 11/01/2009 au 16/01/2009).
2009
van der Bruggen, Pierre. Keynote Lecture: Is it possible to correct the anergy of human tumor-infiltrating lymphocytes?. 9th Jenner Symposium on “Glycobiology and Medicine” of the Royal Society of Medicine (UK) (Brussels, Belgium, du 13/09/2009 au 15/09/2009).
2009
Voland, S. ; Wiesinger, M. ; van der Bruggen, Pierre ; Schuler, G. ; Kaempgen, E.. The galectin disaccharide ligand LacNAc prevents loss of tetramer staining after T cell activation. In: Experimental Dermatology, Vol. 18, no. 3, p. 298. In: Actes de colloque, 2009.
2008
Erfurt, C. ; Haendle, I. ; Schuler-Thurner, B. ; Thielemanns, K. ; van der Bruggen, Pierre ; Schuler, G. ; Schultz, E.. Broad T cell reactivity against a tumour-associated self antigen in melanoma patients and healthy individuals without obvious signs of autoimmunity. 35th Annual Meeting of the Arbeitsgemeinschaft-Dermatolog-Forschung (Eriangen(Germany), Feb 28-mar 01, 2008). In: Experimental Dermatology, Vol. 17, no. 3, p. 251 (2008). In: Actes de colloque, Blackwell Publishing: Oxford, 2008.
2008
Straetemans, Trudy ; Broertjes, Marieke ; Drexhage, Joost ; Coccoris, Miriam ; Lambrecht, Bart ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Gratama, Jan Willem ; Willemsen, Ralph ; Debets, Reno. TCR gene transfer: MHC I and II-restricted MAGE epitopes as melanoma-specific immune targets. 16th Annual Congress of the European-Society-of-Gene-and-Cell-Therapy (Brugge(Belgium), Nov 13-16, 2008). In: Human Gene Therapy, Vol. 19, no. 10, p. 1134-1135 (2008).
2007
Erfurt, C. ; Heirman, C. ; Thielemans, K. ; Zhaojun, S. ; van der Bruggen, Pierre ; Schuler, G. ; Schultz, E. S.. Broad T cell reactivity against a tumor-associated self antigen in melanoma patients and healthy individuals without obvious signs of autoimmunity. Conference on Strategies for Immune Therapy (Mainz(Germany), May 04-05, 2006). In: Cancer Immunology Immunotherapy, Vol. 56, no. 3, p. 418 (2007). In: Actes de colloque, Springer: New York, 2007.
2004
Coulie, Pierre G. ; Lethé, Bernard ; Lurquin, Christophe ; Van Pel, Aline ; Godelaine, Danièle ; van der Bruggen, Pierre ; De Plaen, Etienne ; Brasseur, Francis ; Germeau, Catherine ; Ma , Wenbin ; Thielemans, Kris ; van Baren, Nicolas ; Boon, Thierry ; Germeau, Catherine. Invited Lecture: Monitoring MAGE vaccination. Insights into mechanisms of tumor regression.. 8th International Symposium on Dendritic Cells (Brugge (Belgium), du 17/10/2004 au 21/10/2004).
2000
van der Bruggen, Pierre ; Chaux, Pascal ; Duffour, Marie-Thérèse ; Luiten, Rosalie ; Demotte, Nathalie ; Schultz, Erwin. Keynote Lecture: From the identification of tumor antigens recognized by T cells to immunotherapy. Keystone Symposium (Santa Fe, NM, USA, du 21/01/2000 au 27/01/2000).
1998
Van den Eynde, Benoît ; Chaux, Pascal ; van der Bruggen, Pierre ; Marchand, Marie ; Boon, Thierry. Invited lecture: T cell-defined tumor antigens. European Network of Immunology Institutes Conference, "Pathogenic and Protective T cell responses" (Ile des Embiez, France, du 13/05/1998 au 17/05/1998).
1998
Van den Eynde, Benoît ; Guéguen, M. ; Mandruzzato, S. ; van der Bruggen, Pierre ; Marchand, Marie ; Boon, Thierry. Invited lecture: T cell-defined tumor antigens: perspectives for cancer vaccines. XIIIth Congress of the European Association of Urology (Barcelona, Spain, du 21/03/1998 au 25/03/1998).
1998
Van den Eynde, Benoît ; Guéguen, M. ; Mandruzzato, S. ; van der Bruggen, Pierre ; Marchand, Marie ; Boon, Thierry. Invited lecture: T cell-defined tumor antigens: perspectives for cancer vaccines. International Symposium on Recent Advances of Human Tumor Immunology and Immunotherapy (Sapporo, Japan, du 08/02/1998 au 10/02/1998).
1998
Van den Eynde, Benoît ; Chaux, Pascal ; Morel, Sandra ; van der Bruggen, Pierre ; De Giovanni, G. ; Marchand, Marie ; Boon, Thierry. Invited lecture: The molecular nature of T-cell defined tumor antigens. The Robert Steel Foundation International Symposium (New York, USA, du 21/10/1998 au 23/10/1998).
1998
Van den Eynde, Benoît ; Chaux, Pascal ; Morel, Sandra ; van der Bruggen, Pierre ; De Giovanni, G. ; Marchand, Marie ; Boon, Thierry. Invited lecture: Tumor antigens recognized by T cells: perspectives for cancer vaccines. 13th Annual Society for Biological Therapy Meeting (Pittsburg, USA, du 21/10/1998 au 24/10/1998).
1998
Coulie, Pierre G. ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Marchand, Marie ; Boon, Thierry. Towards vaccination with tumor antigens. In: Naunyn-Schmiedeberg's Archives of Pharmacology, Vol. 358, no. 1, p. R196-R196 (1998).
1997
Boon, Thierry ; Van den Eynde, Benoît ; van der Bruggen, Pierre. Antigens recognized by T lymphocytes on human tumors. 12th International Histocompatibility Workshop & Conference (Paris, France). In: Genetic Diversity of HLA. Functional and Medical Implications (Genetic Diversity of HLA. Functional and Medical Implications; 2), 1997. 9782842540036, p. 75-79.
1997
Coulie, Pierre G. ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Marchand, Marie ; Boon, Thierry. Invited Lecture: "Tumour specific antigens: Perspectives for vaccination". In: European Journal of Cancer, Vol. 33, p. 1299-1299 (1997). doi:10.1016/S0959-8049(97)86209-0.
1997
Van den Eynde, Benoît ; Guéguen, M. ; Mandruzzato, S. ; van der Bruggen, Pierre ; Marchand, Marie ; Coulie, Pierre G. ; Boon, Thierry. Invited lecture: Tumor antigens recognized by T cells: perspectives for the development of cancer vaccines. Annual Meeting of the Swiss Society for Oncology (Lausanne, Switzerland, 07/11/1997).
1997
Van den Eynde, Benoît ; Guéguen, M. ; Mandruzzato, S. ; van der Bruggen, Pierre ; Marchand, Marie ; Boon, Thierry. Invited lecture: Tumor antigens recognized by T lymphocytes. 12th Meeting of the Society for Biological Therapy (Pasadena, USA, du 22/10/1997 au 25/10/1997).
1997
Van den Eynde, Benoît ; Guéguen, M. ; Mandruzzato, S. ; van der Bruggen, Pierre ; Marchand, Marie ; Coulie, Pierre G. ; Boon, Thierry. Invited lecture: Tumor antigens recognized by cytolytic T lymphocytes. 3rd European Conference on Gene Therapy of Cancer (Berlin, Germany, du 11/09/1997 au 13/09/1997).
1995
Boon, Thierry ; van der Bruggen, Pierre ; Brichard, Vincent ; Van Pel, Aline ; Coulie, Pierre G. ; Gaugler, Béatrice ; Van den Eynde, Benoît ; De Plaen, Etienne. Genes coding for tumor rejection antigens. In: European Journal of Cancer, Vol. 31A, p. 995-995 (1995).
1995
van der Bruggen, Pierre ; Van den Eynde, Benoît ; Coulie, Pierre G. ; Brichard, Vincent ; Van Pel, Aline ; De Plaen, Etienne ; Brasseur, Francis ; Boon, Thierry. Genes encoding human tumor-antigens recognized by cytolytic T-lymphocytes. In: Journal of Cellular Biochemistry, , p. 6-6 (1995).
1995
Van den Eynde, Benoît ; Gaugler, Béatrice ; van der Bruggen, Pierre ; Coulie, Pierre G. ; Brichard, Vincent ; Boon, Thierry. Human tumor-antigens recognized by T-cells - Perspectives for new cancer vaccines. 654th Meeting of the Biochemical-Society (Leicester (England), du 04/04/1995 au 07/04/1995). In: Biochemical Society Transactions, Vol. 23, no. 3, p. 681-686 (1995).
1995
Van Pel, Aline ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Brichard, Vincent ; Coulie, Pierre G. ; De Plaen, Etienne ; Guilloux, Y. ; Lucas, Sophie ; Boon, Thierry. Tumor antigens recognized by cytolytic T lymphocytes. The European Cancer Conference 8 (ECCO8) (Paris, France, du 29/10/1995 au 02/11/1995).
1994
Boon-Falleur, Thierry ; Van den Eynde, Benoît ; Hirsch, Hans ; Moroni, Christoph ; De Plaen, Etienne ; van der Bruggen, Pierre ; De Smet, Charles ; Lurquin, Christophe ; Szikora, Jean-Pierre ; De Backer, Olivier. Genes coding for tumor-specific rejection antigens. 59th Symposium on Quantitative Biology (du 02/06/1994 au 08/06/1994). In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology, Vol. 59, p. 617-622 (1994). doi:10.1101/sqb.1994.059.01.070.
1993
Boon, Thierry ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; Traversari, C. ; Lethe, Bernard ; Van Pel, Aline ; Brasseur, Francis ; De Plaen, Etienne ; Chomez, Patrick ; Coulie, Pierre G.. Genes coding for tumor rejection antigens. Colloque de l'INSERM (France). In: De la Recherche oncologique à l'Innovation thérapeutique, P. Tambourin, M. Boiron, John Libbey Eurotext Ltd, 1993. 2-7420-0016-X, p. 1-12.
1993
van der Bruggen, Pierre ; Van den Eynde, Benoît ; Traversari, C. ; Lethe, Bernard ; Van Pel, Aline ; Brasseur, Francis ; De Plaen, Etienne ; Chomez, Patrick ; Coulie, Pierre G. ; Boon, Thierry. Genes encoding tumor rejection antigens. Entretiens Sciences et Défense 1993 (Paris). In: Entretiens Sciences et Défense 1993 (Volume I: Biotechnologies in Life Sciences). Paris, 1993, p. 405-417.
1993
Boon, Thierry ; van der Bruggen, Pierre ; Lurquin, Christophe ; Chomez, Patrick ; Brasseur, Francis ; De Plaen, Etienne ; Van den Eynde, Benoît ; Lethé, Bernard ; Brichard, Vincent ; Van Pel, Aline ; Coulie, Pierre G.. Genes-coding for tumor rejection antigens - Perspectives for cancer-immunotherapy. 10th European Congress of Clinical Chemistry / 12th National Meeting of the Société française de Biologie clinique (EUROLAB 93) (Nice, France, du 25/04/1993 au 29/04/1993). In: Annales de Biologie Clinique, Vol. 51, no. 3-5, p. 279-280 (1993).
1993
Coulie, Pierre G. ; van der Bruggen, Pierre ; Van den Eynde, Benoît ; De Plaen, Etienne ; Chomez, Patrick ; Lurquin, Christophe ; Boon, Thierry. Genetic analysis of human tumor rejection antigens. Symposia on Molecular and Cellular Biology. In: Journal of Cellular Biochemistry, Vol. 53, no. Suppl.17D, p. 92 (1993). In: , Wiley-liss: New York, 1993.
1992
Boon, Thierry ; van der Bruggen, Pierre ; Traversari, C. ; Van den Eynde, Benoît ; Lethe, Bernard ; Chomez, Patrick ; Van Pel, Aline ; Coulie, Pierre G. ; Lurquin, Christophe ; De Plaen, Etienne ; Brasseur, Francis. Genes coding for tumor rejection antigens. 8th International Congress of Immunology (Budapest, Hungary, du 23/08/1992 au 28/08/1992). In: Progress in Immunology, János Gergely, Springer-Verlag Berlin, 1992. 9783540564010, p. 871-873.
1987
van der Bruggen, Pierre. Cassava anthracnose disease: mechanisms contributing to the limitation of the infection, 1987.