Teacher(s)
Demoulin Jean Baptiste; Gualdani Roberta; Lemaigre Frédéric (coordinator); Limaye Nisha; Michiels Thomas; Tyteca Donatienne;
Language
English
Main themes
The main topics are those of the analysis of the interaction between DNA and proteins, the study of gene expression, including manipulation of the expression level, cell imaging, receptor function, and electrophysiology. The integrated use of the tools presented will be further illustrated by recent scientific publications.
Learning outcomes
At the end of this learning unit, the student is able to : | |
| 1 |
At the end of this course, students will be able to use the tools needed to study the function of genes and their expression. Students will also be able to use the tools needed to investigate the subcellular localization and function of the proteins encoded by these genes. |
Content
Protein-DNA interactions and gene regulatory networks
Ectopic gene expression, gene expression inhibition, introduction of nucleic acids in cells
Bulk and single cell RNA sequencing
Next generation sequencing and spatial transcriptomics
Biological and fluorescence imaging
Functional analysis of gene expression
Ectopic gene expression, gene expression inhibition, introduction of nucleic acids in cells
Bulk and single cell RNA sequencing
Next generation sequencing and spatial transcriptomics
Biological and fluorescence imaging
Functional analysis of gene expression
Teaching methods
Lectures
Evaluation methods
Written examination on theoretical issues, data analysis, and methodological choices based on issues raised.
The final mark of the exam results from the global evaluation of the exam, not from the mathematical sum of points collected at individual questions.
The final mark of the exam results from the global evaluation of the exam, not from the mathematical sum of points collected at individual questions.
Other information
Courses grouped into periods of two hours during the first trimester. Courses are given in english.
Online resources
Illustrations and text posted on Moodle.
Teaching materials
- Supports du cours disponibles sur Moodle
Faculty or entity
