Theoretical Approaches in Neurosciences

wsbim2251  2026-2027  Bruxelles Woluwe

Theoretical Approaches in Neurosciences
3.00 credits
20.0 h + 10.0 h
Q2
Teacher(s)
Lee John; Missal Marcus (coordinator);
Language
Prerequisites

The prerequisite(s) for this Teaching Unit (Unité d’enseignement – UE) for the programmes/courses that offer this Teaching Unit are specified at the end of this sheet.
Content
I. Introduction to Theoretical Neuroscience
  • Goal: What is theoretical neuroscience? Its relationship to experimental neuroscience, mathematics, physics, and computer science.
  • Key Topics: The role of theory (prediction, interpretation, synthesis). Levels of analysis (Marr's three levels: computational, algorithmic, implementation). Causality in Neurosciences.
II. The Neuron as a Computational Unit
  • Introduce the fundamental building block and its electrical properties.
  • The Hodgkin-Huxley Model (ionic currents, action potential generation).
  • Integrate-and-Fire models and their variants (e.g., leaky I&F).
III. Neural Encoding and Decoding
  • How does the brain represent information? How can we read it out?
  • Rate coding vs. Temporal coding.
IV. The Bayesian brain hypothesis
  • Predictive Coding (prediction error).
  • Free energy principle.
V. Theoretical Approaches to Deep Learning
  • Bridging the gap between biological neural networks and Artificial Neural Networks (ANNs).
  • Comparing ANNs and the brain (e.g., backpropagation vs. local learning rules).
  • Convolutional Neural Networks (CNNs) as models for the visual cortex.
  • Recurrent Neural Networks (RNNs) and sequence processing.
VI. Oscillations and Neural Synchronization
  • Network rhythms and their functional role.
  • Synchronization, binding problem.
  • Coupled Oscillator Models (Kuramoto model).
  • Different frequency bands (α,β,γ) and their hypothesized functions (e.g., γ oscillations in attention).
Teaching methods
Ex-cathedra lessons, remotely if necessary. Group discussions. Article presentations by students.
Evaluation methods
Oral or written examination (questions with written development or multiple choices).
Online resources
https://moodleucl.uclouvain.be/course/view.php?id=9189
Teaching materials
  • https://moodleucl.uclouvain.be/course/view.php?id=9189
Faculty or entity


Programmes / formations proposant cette unité d'enseignement (UE)

Title of the programme
Sigle
Credits
Prerequisites
Learning outcomes
Master [120] in Biomedicine

Master [60] in Biomedicine