Teacher(s)
Bertrand Luc; Corbet Cyril; Dumoutier Laure; Henriet Patrick; Horman Sandrine; Jonas Jean-Christophe (coordinator); Maggi Pietro;
Language
English
Prerequisites
This course requires good knowledge of cellular and molecular biology, biochemistry of cell metabolism, immunology, cell and organ physiology, and human pathology.
Main themes
The classes will cover the pathophysiological mechanisms underlying the development of frequent non-communicable human diseases, the drugs targeting these mechanisms and unanswered questions on the topic (biomedical research). The link between the molecular, cellular, and tissue alterations and their impact on the whole organism will be highlighted as much as possible. Topics covered during classes (subject to variation depending on the group of teacher in charge): cellular therapy; cardiovascular and respiratory diseases; hemostatic disorders; endothelial dysfunction and vascular remodeling in cardiovascular diseases; neurodegenerative diseases ; cancers; endometriosis ; chronic inflammatory diseases; diabetes.
Learning outcomes
At the end of this learning unit, the student is able to : | |
| - know the pathophysiology of the diseases covered during classes, from the molecule to the cell, the cell to the organ, and the organ to the organism |
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| - understand/be able to explain the link between the molecular and cellular alterations described and the development of the chronic diseases covered during classes, as well as the mode of action of drugs targeting these alterations and their impact in other organs |
|
| - be able to analyze and criticize a conference or paper in that field ; use his/her new knowledge and skills to investigate unanswered questions on the topic |
|
| - imagine new approaches to study the pathophysiology of other diseases |
|
Content
The classes will cover the pathophysiological mechanisms underlying the development of frequent non-communicable human diseases, the drugs targeting these mechanisms and unanswered questions on the topic (biomedical research). The link between the molecular, cellular, and tissue alterations and their impact on the whole organism will be highlighted as much as possible. Topics covered during classes (subject to variation depending on the group of teacher in charge): cellular therapy; cardiovascular and respiratory diseases; hemostatic disorders; endothelial dysfunction and vascular remodeling in cardiovascular diseases; neurological diseases (multiple sclerosis...) ; cancers; endometriosis ; chronic inflammatory diseases; diabetes.
Teaching methods
Depending on the topic, from regular classes to inverted classesor other teaching ways deemed appropriate by the teacher.
Evaluation methods
Written examination or assignment depending on the professor.
In case of a written exam, questions will be in English, answers can be in English or French according to student’s wishes.
For assignments, instructions and evaluation criteria will be detailed by each professor.
The final note will be computed as the geometrical mean of the notes, with equal weight for each professor (final note = root 7th of the product of the 7 notes). As a consequence, the final note will be 0/20 if one assignment (or more) has not been submitted for grading.
In case of a written exam, questions will be in English, answers can be in English or French according to student’s wishes.
For assignments, instructions and evaluation criteria will be detailed by each professor.
The final note will be computed as the geometrical mean of the notes, with equal weight for each professor (final note = root 7th of the product of the 7 notes). As a consequence, the final note will be 0/20 if one assignment (or more) has not been submitted for grading.
Other information
This course requires good knowledge in cellular and molecular biology, biochemical metabolism, immunology, physiology, and pathology.
Online resources
Slides projected during classes and additional documents will be posted on MoodleUCL.
Faculty or entity
