Peptides designed to modulate protein-protein interactions inhibit LDH5 activity, enter cancer cells, and impair proliferation

May 30, 2022 - 1-2pm – Salle Adrienne Gommers (unusual location!)

Dr Ferran NADAL BUFI - Postdoc Medicinal Chemistry (CMFA), LDRI

Related publications:

• Nadal-Bufi F, Mason JM, Chan LY, Craik DJ, Kaas Q, Henriques ST*. (2021). Designed β-hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of Medicinal Chemistry 64, 7. https://doi.org/10.1021/acs.jmedchem.0c01898
• Nadal-Bufi F*, Henriques ST. How to overcome endosomal entrapment of cell penetrating peptides to release the therapeutic potential of peptides. (2020). Peptide Science 112, 6. https://doi.org/10.1002/pep2.24168

Info: raphael.frederick@uclouvain.be