Friday 25 February 2022 – 16 h – auditoire Maisin and on Teams

Gang WANG - FACM/TFAR/LDRI

Reviving disused antibiotics against Gram-negative ESKAPE pathogens: combination with the polyaminoisoprenyl potentiator NV716

Promotor: Françoise Van Bambeke

Related publications:

• Wang, Brunel JM, Bolla JM, Van Bambeke F. The polyaminoisoprenyl potentiator NV716 revives old disused antibiotics against intracellular forms of infection by Pseudomonas aeruginosa. Antimicrob Ag Chemother 2021 Feb 17;65(3):e02028-20
• Wang G, Brunel JM, Preusse M, Mozaheb N, Willger S, Baatsen P, Häussler S, Bolla JM, Van Bambeke F. The polyaminoisoprenyl potentiator NV716 re-sensitizes old disused antibiotics against Pseudomonas aeruginosa by perturbing outer membrane permeability. Submitted for publication
• Wang G, Brunel JM, Bolla JM, Van Bambeke F. The polyamino-isoprenyl potentiator NV716 revives disused antibiotics against intracellular forms of infection by Escherichia coli, Klebsiella pneumoniae, and Acinetobacter baumannii. Submitted for publication

Info : francoise.vanbambeke@uclouvain.be