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Photo of Antoine Christiaens

Antoine Christiaens

Chercheur qualifié FNRS, Professeur
antoine.christiaens@uclouvain.be

SSS/LDRI Louvain Drug Research Institute (LDRI)

SSS/MEDE Faculté de médecine et médecine dentaire (MEDE)

2026
Article de journal

de Terwangne, C., Henrard, S., Marien, S., Steinman, M., Boland, B., & Christiaens, A. (2026). Diabetes overtreatment and flags for deprescribing glucose‐lowering treatment in geriatric inpatients with type 2 diabetes: Prognostic insights from a longitudinal cohort. Diabetic Medicine: journal of diabetes UK, 1-10. https://doi.org/10.1111/dme.70435 (Original work published 2026)

https://research.dial.uclouvain.be/handle/2078.5/279550


Lecomte, E., Arys, M., Christiaens, A., Doyen, L., Marot, J., Verbelen, V., & Wieërs, G. (2026). Prioritizing cefuroxime as empirical treatment in acute bacterial prostatis: patient characteristics and outcomes. JAC Antimicrobial Resistance. Accepted/in-press. (Original work published 2026)

https://research.dial.uclouvain.be/handle/2078.5/265190


2025
Article de journal

Christiaens, A., Boureau, A.-S., Hadjadj, S., & Cariou, B. (2025). Response to the Comment on Christiaens et al. Diabetes overtreatment and hypoglycemia in older patients with type 2 diabetes on insulin therapy: insights from the HYPOAGE cohort study. Diabetes Care 2025;48:61–66. Diabetes Care. Accepted/in-press. (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/258446


Aponte Ribero, V., Efthimiou, O., Abolhassani, N., Alwan, H., Bauer, D. C., Henrard, S., Christiaens, A., O’Mahony, D., Knol, W., Peters, M. J. L., Chiolero, A., Aujesky, D., Waeber, G., Rodondi, N., Del Giovane, C., & Gencer, B. (2025). Diabetes and the risk of cardiovascular events and all‐cause mortality among older adults: an individual participant data analysis of five prospective studies. European Journal of Clinical Investigation, 55(2). https://doi.org/10.1111/eci.14340 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/248295


Christiaens, A., Cochard, A., Tubach, F., Thompson, W., Sinclair, A. J., Henrard, S., Boland, B., Slaouti-Jégou, Y., Lekens, B., Bonnet-Zamponi, D., Simon-Tillaux, N., & Zerah, L. (2025). Association between hypoglycaemic drug de-intensification, mortality and hospital admission in older adults with type 2 diabetes: a cohort study emulating a target trial. Age and Ageing, 54(6). https://doi.org/10.1093/ageing/afaf160 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/246478


Aponte Ribero, V., Baretella, O., Del Giovane, C., Haller, M., Feller, M., Boland, B., Christiaens, A., Knol, W., O’Mahony, D., Gastens, V., Gencer, B., Baggio, S., & Rodondi, N. (2025). Target trial emulation of statin discontinuation in multimorbid older adults with polypharmacy. European Journal of Clinical Investigation. Accepted/in-press. https://doi.org/10.1111/eci.70126 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/265333


Kahkoska, A. R., Neumiller, J. J., Alexopoulos, A.-S., Christiaens, A., Cukierman-Yaffe, T., Ehrhardt, N. M., Huang, E. S., Idrees, T., Laffel, L. M., Lee, S. J., Pandya, N., Pratley, R. E., Rodriguez-Mañas, L., Slyne, C., Toschi, E., Weinstock, R. S., Wisniewski, A., Wysham, C., & Munshi, M. (2025). Preparing to Meet the Needs of a Growing Older Adult Population with Type 1 Diabetes: A Narrative Review. Journal of General Internal Medicine. Accepted/in-press. https://doi.org/10.1007/s11606-025-10053-3 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/265328


Boccardi, V., Bahat, G., Balci, C., Bourdel-Marchasson, I., Christiaens, A., Donini, L. M., Cavdar, S., Maggi, S., Özkök, S., Pavic, T., Perkisas, S., Volpato, S., Zaidi, M. S., Zeyfang, A., & Sinclair, A. J. (2025). Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)—Special Interest Group in Diabetes. European Geriatric Medicine. Accepted/in-press. https://doi.org/10.1007/s41999-025-01168-1 (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/242888


Christiaens, A. (2025). Optimisation du traitement anti-hyperglycémiant chez les personnes âgées vivant avec diabète de type 2 : enjeux du surtraitement et de la déprescription. Louvain médical, 144(3), 16-20. (Original work published 2025)

https://research.dial.uclouvain.be/handle/2078.5/248899


Papier de conférence

Christiaens, A. (2025). Optimisation du traitement anti-hyperglycémiant chez les personnes âgées vivant avec diabète de type 2 : Enjeux du surtraitement et de la déprescription. Congrès UCLouvain d’Endocrino-Diabétologie, Bruxelles, Belgique.

https://research.dial.uclouvain.be/handle/2078.5/265193


Christiaens, A. (2025). Hypoglycemia in Nursing Home residents living with type 2 diabetes. International Geriatric Diabetes Society.

https://research.dial.uclouvain.be/handle/2078.5/265188


Christiaens, A. (2025). Statistical calibration of OPTIMISE trial results using real-world data. Hypertension group seminar, University of Oxford.

https://research.dial.uclouvain.be/handle/2078.5/265189


Christiaens, A. (2025). Diabetes overtreatment and Deprescribing in Older Adults living with Type 2 Diabetes. Nuffield Department of Primary Care Health Sciences seminar, University of Oxford.

https://research.dial.uclouvain.be/handle/2078.5/265192


Chapitre de livre

Christiaens, A. (2025). 17 - Deintensification of therapy. In Alan Sinclair, Ahmed Abdelhafiz (ed.), Care of Older People with Diabetes - A Manual for Healthcare Practice (6th ed., p. p. 448). Wiley-Blackwell.

https://research.dial.uclouvain.be/handle/2078.5/236981


2024
Article de journal

Morel, T., Heinrich, C. H., Zerah, L., Hurley, E., Christiaens, A., & Fournier, J.-P. (2024). Use of deprescribing search filters in systematic review search strategies: A case study. Basic & Clinical Pharmacology & Toxicology, 134(1), 116-120. https://doi.org/10.1111/bcpt.13908 (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/242526


Christiaens, A. (2024). Eerstelijnsaanpak van type 2-diabetes bij oudere personen : behandelingsstrategie op maat van de patiënt. Medi-Sfeer, 766, 20-25. (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/233487


Mellot, M., Jawal, L., Morel, T., Fournier, J.-P., Tubach, F., Cadwallader, J.-S., Christiaens, A., & Zerah, L. (2024). Barriers and Enablers for Deprescribing Glucose-Lowering Treatment in Older Adults: A Systematic Review. Journal of the American Medical Directors Association, 25(3), 439-447. https://doi.org/10.1016/j.jamda.2023.11.025 (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/237150


Christiaens, A. (2024). From burden to benefits: new promises of glucose-lowering treatments in older adults. Age and Ageing, 53(12), afae265 [1-2]. https://doi.org/10.1093/ageing/afae265 (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/263088


Christiaens, A. (2024). Prise en charge du diabète de type 2 chez les personnes âgées en première ligne : individualisation de la stratégie thérapeutique. Medi-Sphère, 766, 20-25. (Original work published 2024)

https://research.dial.uclouvain.be/handle/2078.5/233486


Papier de conférence

Christiaens, A. (2024). Interactions between Comorbidities and Aging-related Conditions in Older Adults with Diabetes. International Geriatric Diabetes Society, Boston, USA.

https://research.dial.uclouvain.be/handle/2078.5/238441


Christiaens, A. (2024). Deprescribing Antihyperglycemic Treatments and Hypoglycemia in Older Adults with Type 2 Diabetes. Geriatric Diabetes Days, Nantes, France.

https://research.dial.uclouvain.be/handle/2078.5/238442


Christiaens, A., & et al. (2024). EFFECT OF DE-INTENSIFYING HYPOGLYCAEMIC DRUGS IN OLDER ADULTS WITH TYPE 2 DIABETES: A COHORT STUDY EMULATING A TARGET TRIAL. Di-Prescribe, Bruxelles, Belgique.

https://research.dial.uclouvain.be/handle/2078.5/238450


Christiaens, A. (2024). Overtreatment and Therapeutic De-escalation in Elderly Patients. National Days of Endocrinology (College of Endocrinology, Diabetes, and Metabolic Diseases Teachers), Paris, France.

https://research.dial.uclouvain.be/handle/2078.5/238446


2023
Papier de conférence

Christiaens, A. (2023). Choosing Therapeutic Targets for Antihyperglycemic Treatments in Elderly Patients with Type 2 Diabetes. Autumn Days of the French Society of Geriatrics and Gerontology, Paris, France.

https://research.dial.uclouvain.be/handle/2078.5/238445


Article de journal

Christiaens, A., Henrard, S., Boland, B., & Sinclair, A. J. (2023). Overtreatment of older people with type 2 diabetes - a high impact frequent occurrence in need of a new definition. Diabetic Medicine: journal of diabetes UK, 40(2), e14994 [1-8]. https://doi.org/10.1111/dme.14994 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/216113


Christiaens, A., Baretella, O., Del Giovane, C., Rodondi, N., Knol, W., Peters, M., Jennings, E., O’Mahony, D., Spinewine, A., Boland, B., & Henrard, S. (2023). Association between diabetes overtreatment in older multimorbid patients and clinical outcomes: an ancillary European multicentre study. Age and Ageing, 52(1 (2023)), afac320 [1-8]. https://doi.org/10.1093/ageing/afac320 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/232176


Bourdel-Marchasson, I., Maggi, S., Abdelhafiz, A., Bellary, S., Demurtas, J., Forbes, A., Ivory, P., Rodríguez-Mañas, L., Sieber, C., Strandberg, T., Tessier, D., Vergara, I., Veronese, N., Zeyfang, A., Christiaens, A., & Sinclair, A. (2023). Essential steps in primary care management of older people with Type 2 diabetes: an executive summary on behalf of the European geriatric medicine society (EuGMS) and the European diabetes working party for older people (EDWPOP) collaboration. Aging Clinical and Experimental Research, 35(11), 2279-2291. https://doi.org/10.1007/s40520-023-02519-3 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/213051


Christiaens, A., & Sinclair, A. J. (2023). Comment on: Data-driven classification of health status of older adults with diabetes: The diabetes and aging study. Journal of the American Geriatrics Society, 71(9), 2995-2996. https://doi.org/10.1111/jgs.18470 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/217753


Baretella, O., Alwan, H., Feller, M., Aubert, C. E., Del Giovane, C., Papazoglou, D., Christiaens, A., Meinders, A.-J., Byrne, S., Kearney, P. M., O’Mahony, D., Knol, W., Boland, B., Gencer, B., Aujesky, D., & Rodondi, N. (2023). Overtreatment and associated risk factors among multimorbid older patients with diabetes. Journal of the American Geriatrics Society, 71(9), 2893-2901. https://doi.org/10.1111/jgs.18465 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/217644


Christiaens, A., Bordier, L., Doucet, J., & Bauduceau, B. (2023). Particularités d’utilisation des traitements antihyperglycémiants chez les patients âgés. Médecine des Maladies Métaboliques, 17(8), 8S90-8S95. https://doi.org/10.1016/s1957-2557(23)00304-8 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/217604


Christiaens, A., Simon-Tillaux, N., Thompson, W., Sinclair, A. J., Henrard, S., Boland, B., Slaouti-Jégou, Y., Lekens, B., Bonnet-Zamponi, D., Tubach, F., & Zerah, L. (2023). Impact of deintensifying hypoglycaemic drugs in older adults with type 2 diabetes: protocol for an emulation of a target trial. BMJ open, 13(11), e073081 [1-9]. https://doi.org/10.1136/bmjopen-2023-073081 (Original work published 2023)

https://research.dial.uclouvain.be/handle/2078.5/216622


2022
Thèse

Christiaens, A. (2022). Implications of health and metabolic heterogeneities for glycaemic management in older patients with type 2 diabetes.

https://research.dial.uclouvain.be/handle/2078.5/110590


Papier de conférence

Christiaens, A. (2022). Implications of Health and Metabolic Heterogeneities for Glycemic Management in Older Patients with Type 2 Diabetes. Académie Royale de Médecine de Belgique, séance académique de remise des prix, Bruxelles, Belgique.

https://research.dial.uclouvain.be/handle/2078.5/238448


Christiaens, A. (2022). Diabetes and Elderly Patients: Heterogeneities and Individualization of Treatment. Geriatrics Days in Nouvelle Aquitaine, Bordeaux, France.

https://research.dial.uclouvain.be/handle/2078.5/238447


Christiaens, A. (2022). The Elderly Diabetic Patient: A Comprehensive and Personalized Approach. Pharmacy Days URPS, Lille, France.

https://research.dial.uclouvain.be/handle/2078.5/238449


Article de journal

Christiaens, A., Henrard, S., & Boland, B. (2022). Large discrepancy in glycaemic control appropriateness in geriatric patients with type 2 diabetes according to major clinical practice guidelines. European Geriatric Medicine, 13(3), 753-758. https://doi.org/10.1007/s41999-021-00594-1 (Original work published 2022)

https://research.dial.uclouvain.be/handle/2078.5/216119


2021
Article de journal

Christiaens, A., Henrard, S., Zerah, L., Dalleur, O., Bourdel-Marchasson, I., & Boland, B. (2021). Individualisation of glycaemic management in older people with type 2 diabetes: a systematic review of clinical practice guidelines recommendations. Age and Ageing, 50(6), 1935-1942. https://doi.org/10.1093/ageing/afab157 (Original work published 2021)

https://research.dial.uclouvain.be/handle/2078.5/216131


Papier de conférence

Christiaens, A., Boland, B., & Henrard, S. (2021). 530 INTERPRETATION OF HBA1C VALUES IN GERIATRIC PATIENTS WITH TYPE 2 DIABETES: LARGE DIVERGENCE BETWEEN CLINICAL PRACTICE GUIDELINES. Age and Ageing, 50(Supplement_2), ii1-ii4. https://doi.org/10.1093/ageing/afab117.11 (Original work published 2021)

https://research.dial.uclouvain.be/handle/2078.5/216124


2020
Article de journal

Christiaens, A., Boland, B., Germanidis, M., Dalleur, O., & Henrard, S. (2020). Poor health status, inappropriate glucose-lowering therapy and high one-year mortality in geriatric patients with type 2 diabetes. BMC Geriatrics, 20(1). https://doi.org/10.1186/s12877-020-01780-9 (Original work published 2020)

https://research.dial.uclouvain.be/handle/2078.5/23695


Papier de conférence

Baretella, O., Papazoglou, D., Feller, M., Christiaens, A., Meinders, A., Byrne, S., Kearny, P., O’Mahony, D., Knol, W., Boland, B., Aujesky, D., & Rodondi, N. (2020). Is type 2 diabetes mellitus appropriately treated in multimorbid elderly patients? Sources of potential overtreatment. Spring Congress of the Swiss Society of General Internal Medicine, Basel (CH).

https://research.dial.uclouvain.be/handle/2078.5/112466


2019
Papier de conférence

Christiaens, A., Germanidis, M., Henrard, S., & Boland, B. (2019). Appropriateness of glucose-lowering therapy in geriatric patients with type 2 diabetes: factors associated with glucose-lowering therapy at high risk of hypoglycaemia. Doctoral day – Thematic doctoral school SPSS 2019, Louvain-la-Neuve.

https://research.dial.uclouvain.be/handle/2078.5/216150


Article de journal

Christiaens, A., Hermans, M., Boland, B., & Henrard, S. (2019). Distinction of cardiometabolic profiles among people ≥ 75 years with type 2 diabetes: A latent profile analysis. BMC Endocrine Disorders, 19(1), 85 [1-10]. https://doi.org/10.1186/s12902-019-0411-2 (Original work published 2019)

https://research.dial.uclouvain.be/handle/2078.5/216149


2018
Papier de conférence

Boland, B., Germanidis, M., Christiaens, A., Chérif, M., Dalleur, O., & Henrard, S. (2018). Sur-traitement hypoglycémiant chez les patients gériatriques avec diabète de type 2. 11ème Congrès international francophone de gérontologie et gériatrie (CIFGG), Montreux, CH.

https://research.dial.uclouvain.be/handle/2078.5/216166


Vanderhofstadt, M., Moreau, A., de La Serna, I., Luyx, C., Repoussez, C., & Christiaens, A. (2018). Impact de la dysphagie sur l’administration des médicaments. 11ème Congrès international francophone de gérontologie et gériatrie (CIFGG), Montreux, CH.

https://research.dial.uclouvain.be/handle/2078.5/124888


Christiaens, A., Hermans, M., Boland, B., & Henrard, S. (2018). Latent Profile Analysis of the metabolic phenotype classified patients ≥75 years with type 2 diabetes into six distinct groups. Doctoral day – Thematic doctoral school SPSS 2018, Liège.

https://research.dial.uclouvain.be/handle/2078.5/26458


2017
Papier de conférence

Christiaens, A., Ngueliapi, Y., Henrard, S., Dalleur, O., & Boland, B. (2017). Prescription médicamenteuse cardiovasculaire inappropriée chez des patients âgés diabétiques. Journées d’Automne - Société belge de gériatrie et gérontologie (SBGG), Liège, BE.

https://research.dial.uclouvain.be/handle/2078.5/229895


2016
Article de journal

Christiaens, A., Deprez, P., Amyere, M., Mendola, A., Bernard, P., Gillerot, Y., Clapuyt, P., Godfraind, C., Lengelé, B., Vikkula, M., & Behets Wydemans, C. (2016). Isolated bilateral transverse agenesis of the distal segments of the lower limbs at the level of the knee joint in a human fetus. American Journal of Medical Genetics. Part A, 170(2), 523-530. https://doi.org/10.1002/ajmg.a.37462 (Original work published 2016)

https://research.dial.uclouvain.be/handle/2078.5/180916


2014
Papier de conférence

Christiaens, A., Beeckmans, M., Hermans, M., & Boland, B. (2014). Increased frailty in older patients with type 2 diabetes and malnutrition. Geriatrie et Psychologie Neuropsychiatrie du Vieillissement, 12(Suppl. 3), 16. (Original work published 2014)

https://research.dial.uclouvain.be/handle/2078.5/124913


Unités d'enseignement pour 2026

Libellé Code
Scientific writing in health sciences and social approaches of health (quantitative and qualitative methods) WESP2227
Epidémiologie, santé publique et soins de santé WMDS1113
Année Libellé Établissement
2022 Docteur en sciences médicales UCLouvain | Université catholique de Louvain (Belgique)
2014 Médecin UCLouvain | Université catholique de Louvain (Belgique)