SST/EPL Ecole polytechnique de Louvain (EPL)
Adresse postale
ELEN - StevinL5.04.04
Place du Levant 2
1348 Louvain-la-Neuve
Réseaux sociaux
L5.04.04
Place du Levant 2
1348 Louvain-la-Neuve
2025
Article de journal
Wuyckens, S., Janssens, G., Chocan Vera, M., Sundström, J., Di Perri, D., Sterpin, E., Souris, K., & Lee, J. (2025). Proton arc therapy plan optimization with energy layer pre-selection driven by organ at risk sparing and delivery time. Physics in Medicine & Biology, 70(4), 45003. https://doi.org/10.1088/1361-6560/adad2d (Original work published 2025)
2024
Article de journal
Mein, S., Wuyckens, S., Li, X., Both, S., Carabe, A., Chocan Vera, M., Engwall, E., Francesco, F., Graeff, C., Gu, W., Hong, L., Inaniwa, T., Janssens, G., de Jong, B., Li, T., Liang, X., Liu, G., Lomax, A., Mackie, T., et al. (2024). Particle arc therapy: Status and potential. Radiotherapy & Oncology, 199, 110434 [1-23]. https://doi.org/10.1016/j.radonc.2024.110434 (Original work published 2024)
2023
Article de journal
Wuyckens, S., Dasnoy-Sumell, D., Janssens, G., Hamaide, V., Huet, M., Loyen, E., Macq, B., Rotsart de Hertaing, G., & et al. (2023). OpenTPS -- Open-source treatment planning system for research in proton therapy. Medical Physics. Published. https://doi.org/10.48550/arXiv.2303.00365 (Original work published 2023)
2022
Article de journal
Wuyckens, S., Saint-Guillain, M., Janssens, G., Zhao, L., Li, X., Ding, X., Sterpin, E., Lee, J. A., & Souris, K. (2022). Treatment planning in arc proton therapy: Comparison of several optimization problem statements and their corresponding solvers. Computers in Biology and Medicine, 148(1), 105609. https://doi.org/10.1016/j.compbiomed.2022.105609 (Original work published 2022)
Wuyckens, S., Zhao, L., Saint-Guillain, M., Janssens, G., Sterpin, E., Souris, K., Ding, X., & Lee, J. (2022). Bi-criteria Pareto optimization to balance irradiation time and dosimetric objectives in proton arc therapy. Physics in Medicine & Biology, 67(24), 245017. https://doi.org/10.1088/1361-6560/aca5e9 (Original work published 2022)
2021
Article de journal
Li, X., Ding, X., Zheng, W., Liu, G., Janssens, G., Souris, K., Barragán-Montero, A. M., Yan, D., Stevens, C., & Kabolizadeh, P. (2021). Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study. Frontiers in Oncology, 11, 698537 [1-9]. https://doi.org/10.3389/fonc.2021.698537 (Original work published 2021)
Patch, S. K., Nguyen, C., Dominguez-Ramirez, D., Labarbe, R., Janssens, G., Cammarano, D., Lister, J., Finch, C., Lambert, J., Pandey, J., Bennett, C., Porteous, E., Chirvase, C., Cohilis, M., Souris, K., Ono, S., & Lynch, T. (2021). Thermoacoustic range verification during pencil beam delivery of a clinical plan to an abdominal imaging phantom. Radiotherapy & Oncology, 159, 224-230. https://doi.org/10.1016/j.radonc.2021.03.027 (Original work published 2021)
2020
Article de journal
Guterres Marmitt, G., Pin, A., Ng Wei Siang, K., Janssens, G., Souris, K., Cohilis, M., Langendijk, J. A., Both, S., Knopf, A., & Meijers, A. (2020). Platform for automatic patient quality assurance via Monte Carlo simulations in proton therapy. Physica Medica : an international journal devoted to the applications of physics to medicine and biology, 70, 49-57. https://doi.org/10.1016/j.ejmp.2019.12.018 (Original work published 2020)
2019
Article de journal
Albert, J., Labarbe, R., Janssens, G., Souris, K., & Sterpin, E. (2019). Estimation of respiratory phases during proton radiotherapy from a 4D-CT and Prompt gamma detection profiles. Physica Medica : an international journal devoted to the applications of physics to medicine and biology, 64, 33-39. https://doi.org/10.1016/j.ejmp.2019.06.006 (Original work published 2019)
Souris, K., Barragan Montero, A. M., Janssens, G., Di Perri, D., Sterpin, E., & Lee, J. (2019). Technical Note: Monte Carlo methods to comprehensively evaluate the robustness of 4D treatments in proton therapy. Medical Physics, 46(10), 4676-4684. https://doi.org/10.1002/mp.13749 (Original work published 2019)
2018
Article de journal
Huang, S., Souris, K., Li, S., Kang, M., Barragan Montero, A. M., Janssens, G., Lin, A., Garver, E., Ainsley, C., Taylor, P., Xiao, Y., & Lin, L. (2018). Validation and application of a fast Monte Carlo algorithm for assessing the clinical impact of approximations in analytical dose calculations for pencil beam scanning proton therapy. Medical Physics, 45(12), 5631-5642. https://doi.org/10.1002/mp.13231 (Original work published 2018)
Di Perri, D., Colot, A., Delor, A., Ghoul, R., Janssens, G., Lacroix, V., Matte, P., Robert, A., Souris, K., & Geets, X. (2018). Effect of continuous positive airway pressure administration during lung stereotactic ablative radiotherapy: a comparative planning study. Strahlentherapie und Onkologie, 194(6), 591-599. https://doi.org/10.1007/s00066-018-1278-2 (Original work published 2018)
Bernatowicz, K., Geets, X., Barragan Montero, A. M., Janssens, G., Souris, K., & Sterpin, E. (2018). Feasibility of online IMPT adaptation using fast, automatic and robust dose restoration. Physics in Medicine and Biology, 63(8), 085018 [1-13]. https://doi.org/10.1088/1361-6560/aaba8c (Original work published 2018)
Papier de conférence
Janssens, G., William Scott Ingram, Sheng Huang, Minglei Kang, Souris, K., Kevin Teo, & Liyong Lin. (2018). Development of Virtual 4DCT for Image Guided Proton Therapy. PTCOG.
Sheng Huang, Souris, K., Siyang Li, Minglei Kang, & Janssens, G. (2018). Assessing the clinical impact of TPS dose calculation for proton PBS treatment using fast Monte Carlo algorithm. PTCOG.
Sheng Huang, Souris, K., S Li, Minglei Kang, Janssens, G., & Liyong Lin. (2018). Assessment of Clinical Impact of Analytical Dose Calculation in TPS for Proton PBS Treatment Using Fast Monte Carlo Simulation. International Journal of Radiation: Oncology - Biology - Physics, 102(3), S57-S58. (Original work published 2018)
2017
Article de journal
Di Perri, D., Lee, J., Bol, A., Hanin, F.-X., Janssens, G., Labar, D., Robert, A., Sterpin, E., & Geets, X. (2017). Correlation analysis of [18F]fluorodeoxyglucose and [18F]fluoroazomycin arabinoside uptake distributions in lung tumours during radiation therapy. Acta Oncologica, 56, 1181-1188. https://doi.org/10.1080/0284186x.2017.1329594 (Original work published 2017)
Di Perri, D., Lee, J., Bol, A., Hanin, F.-X., Janssens, G., Labar, D., Robert, A., Sterpin, E., & Geets, X. (2017). Evolution of [18F]fluorodeoxyglucose and [18F]fluoroazomycin arabinoside PET uptake distributions in lung tumours during radiation therapy. Acta Oncologica, 56(4), 516-524. https://doi.org/10.1080/0284186X.2017.1287943 (Original work published 2017)
Wanet, M., Delor, A., Hanin, F.-X., Ghaye, B., Van Maanen, A., Remouchamps, V., Clermont, C., Goossens, S., Lee, J., Janssens, G., Bol, A., & Geets, X. (2017). An individualized radiation dose escalation trial in non-small cell lung cancer based on FDG-PET imaging. Strahlentherapie und Onkologie, 193(10), 812-822. https://doi.org/10.1007/s00066-017-1168-z (Original work published 2017)
Lin, L., Souris, K., Kang, M., Glick, A., Lin, H., Huang, S., Stützer, K., Janssens, G., Sterpin, E., Lee, J., Solberg, T. D., McDonough, J. E., Simone, C. B., & Ben-Josef, E. (2017). Evaluation of motion mitigation using abdominal compression in the clinical implementation of pencil beam scanning proton therapy of liver tumors. Medical Physics, 44, 703-712. https://doi.org/10.1002/mp.12040 (Original work published 2017)
2016
Article de journal
Mory, C., Janssens, G., & Rit, S. (2016). Motion-aware temporal regularization for improved 4D cone-beam computed tomography. Physics in Medicine and Biology, 61(18), 6856-6877. https://doi.org/10.1088/0031-9155/61/18/6856 (Original work published 2016)
Janssens, G., Smeets, J., Vander Stappen, F., Prieels, D., Clementel, E., Hotoiu, E.-L., & Sterpin, E. (2016). Sensitivity study of prompt gamma imaging of scanned beam proton therapy in heterogeneous anatomies. Radiotherapy & Oncology, 118(3), 562-567. https://doi.org/10.1016/j.radonc.2015.11.002 (Original work published 2016)
Differding, S., Sterpin, E., Janssens, G., Hanin, F.-X., Lee, J., & Grégoire, V. (2016). Methodology for adaptive and robust FDG-PET escalated dose painting by numbers in head and neck tumors. Acta Oncologica, 55(2), 217-225. https://doi.org/10.3109/0284186X.2015.1046997 (Original work published 2016)
Macq, B., Xing, Y., Bondar, M. L., & Janssens, G. (2016). Prompt Gamma Imaging-Based Prediction of Bragg Peak Position for Realistic Treatment Error Scenarios. Medical Physics, 43(6), 3456. https://doi.org/10.1118/1.4956116 (Original work published 2016)
Papier de conférence
Souris, K., Glick, A., Janssens, G., Sterpin, E., Lee, J., & Lin, L. (2016). Study of the interplay between breathing motion and PBS delivery for liver cancer. BHPA.
2015
Article de journal
Sterpin, E., Janssens, G., Smeets, J., Van der Stappen, F., Prieels, D., Priegnitz, M., Perali, I., & Vynckier, S. (2015). Analytical computation of prompt gamma ray emission and detection for proton range verification. Physics in Medicine and Biology, 60(12), 4915-4946. https://doi.org/10.1088/0031-9155/60/12/4915 (Original work published 2015)
Landry, G., Dedes, G., Zöllner, C., Handrack, J., Janssens, G., Orban de Xivry, J., Reiner, M., Paganelli, C., Riboldi, M., Kamp, F., Söhn, M., Wilkens, J. J., Baroni, G., Belka, C., & Parodi, K. (2015). Phantom based evaluation of CT to CBCT image registration for proton therapy dose recalculation. Physics in Medicine and Biology, 60(2), 595-613. https://doi.org/10.1088/0031-9155/60/2/595 (Original work published 2015)
Cambraia Lopes, P., Clementel, E., Crespo, P., Henrotin, S., Huizenga, J., Janssens, G., Parodi, K., Prieels, D., Roellinghoff, F., Smeets, J., Stichelbaut, F., & Schaart, D. R. (2015). Time-resolved imaging of prompt-gamma rays for proton range verification using a knife-edge slit camera based on digital photon counters. Physics in Medicine and Biology, 60(15), 6063-6085. https://doi.org/10.1088/0031-9155/60/15/6063 (Original work published 2015)
Goossens, S., Descampe, A., Orban de Xivry, J., Lee, J., Delor, A., Janssens, G., & Geets, X. (2015). Impact of motion induced artifacts on automatic registration of lung tumors in Tomotherapy. Physica Medica : an international journal devoted to the applications of physics to medicine and biology, 31(8), 963-968. https://doi.org/10.1016/j.ejmp.2015.07.140 (Original work published 2015)
Sterpin, E., Differding, S., Janssens, G., Geets, X., Grégoire, V., & Lee, J. (2015). Generation of prescriptions robust against geometric uncertainties in dose painting by numbers. Acta Oncologica, 54(2), 253-260. https://doi.org/10.3109/0284186X.2014.930171 (Original work published 2015)
Papier de conférence
Sterpin, E., Janssens, G., Smeets, J., Vander Stappen, F., Priegnitz, M., Perali, I., Prieels, D., & Vynckier, S. (2015). TH-CD-BRA-03: Experimental Validation of An Analytical Model for Prompt Gamma Imaging. Medical Physics, 42(6), 3726. https://doi.org/10.1118/1.4926228 (Original work published 2015)
2014
Papier de conférence
Gallego Ortiz, N., Orban de Xivry, J., Descampe, A., Goossens, S., Geets, X., Janssens, G., & Macq, B. (2014). Respiratory motion variations from skin surface on lung cancer patients from 4D CT data. Progress in Biomedical Optics and Imaging, 9034, 90342Y. https://doi.org/10.1117/12.2043477 (Original work published 2014)
Article de journal
Wanet, M., Sterpin, E., Janssens, G., Delor, A., Lee, J., & Geets, X. (2014). Validation of the mid-position strategy for lung tumors in helical TomoTherapy. Radiotherapy & Oncology, 110(3), 529-537. https://doi.org/10.1016/j.radonc.2013.10.025 (Original work published 2014)
Goossens, S., Senny, F., Lee, J., Janssens, G., & Geets, X. (2014). Assessment of tumor motion reproducibility with audio-visual coaching through successive 4D CT sessions. Journal of Applied Clinical Medical Physics, 15(1), 47-56. https://doi.org/10.1120/jacmp.v15i1.4332 (Original work published 2014)
Bol, V., Bol, A., Bouzin, C., Labar, D., Lee, J., Janssens, G., Porporato, P., Sonveaux, P., Feron, O., & Grégoire, V. (2014). Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation. Acta Oncologica, 54(2), 266-274. https://doi.org/10.3109/0284186X.2014.932006 (Original work published 2015)
2013
Papier de conférence
Wanet, M., Sterpin, E., Janssens, G., Delor, A., Lee, J., & Geets, X. (2013). Validation of the mid-position strategy for lung tumors in helical tomotherapy. Belgian Hospital Physicist Association Symposium 2012, Mechelen, Belgium.
Sterpin, E., Differding, S., Janssens, G., Grégoire, V., & Lee, J. (2013). Dose painting by numbers: a universal method to ensure the robustness of heterogeneous prescriptions against geometric uncertainties. 2013 Symposium of Belgian Hospital Physicist Association, Mechelen, Belgium.
2012
Papier de conférence
Orban de Xivry, J., Janssens, G., Denis, J.-M., Sterpin, E., Prieels, D., & Vynckier, S. (2012). Is the patient a good detector for in-vivo dosimetry? Belgian Hospital Physicist Association Symposium 2012, Brussels.
Denis, J.-M., Prieels, D., Janssens, G., Orban de Xivry, J., Sterpin, E., & Vynckier, S. (2012). Dosimétrie in-vivo : le patient utilisé comme détecteur. Symposium 2012 de la société française de physique médicale, Strasbourg.
Janssens, G., Geets, X., Orban de Xivry, J., Goossens, S., Delor, A., Wanet, M., Lee, J., Vynckier, S., Grégoire, V., & Sterpin, E. (2012). 4D validation of dynamic treatment delivery for lung tumors. Belgian Hospital Physicist Association Symposium 2012, Brussels.
Sterpin, E., Janssens, G., Orban de Xivry, J., Goossens, S., Delor, A., Wanet, M., Lee, J., Vynckier, S., & Geets, X. (2012). OC-0378 helical tomotherapy dynamics are not an issue to treat lung tumors for patients coached to ensure regular breathing. Radiotherapy & Oncology, 103, S151-S152. https://doi.org/10.1016/S0167-8140(12)70717-X (Original work published 2012)
Article de journal
Sterpin, E., Janssens, G., Orban de Xivry, J., Goossens, S., Wanet, M., Lee, J., Bol, V., Delor, A., Vynckier, S., Grégoire, V., & Geets, X. (2012). Helical tomotherapy SIB and hypo-fractionated stereotactic treatments of lung tumors without gating or tracking: a 4D Monte Carlo treatment planning study. Radiotherapy & Oncology, 104(2), 173-180. https://doi.org/10.1016/j.radonc.2012.06.005 (Original work published 2012)
2011
Article de journal
van den Bogaard, J., Janssen, M. H. M., Janssens, G., Buijsen, J., Reniers, B., Lambin, P., Lammering, G., & Ollers, M. C. (2011). Residual metabolic tumor activity after chemo-radiotherapy is mainly located in initially high FDG uptake areas in rectal cancer. Radiotherapy & Oncology, 99(2), 137-141. https://doi.org/10.1016/j.radonc.2011.04.004 (Original work published 2011)
Janssens, G., Jacques, L., Orban de Xivry, J., Geets, X., & Macq, B. (2011). Diffeomorphic Registration of Images with Variable Contrast Enhancement. International Journal of Biomedical Imaging, 2011(1), 16. https://doi.org/10.1155/2011/891585 (Original work published 2011)
Papier de conférence
Sterpin, E., Orban de Xivry, J., Geets, X., Goossens, S., Wanet, M., Mackie, T. R., Vynckier, S., Grégoire, V., & Janssens, G. (2011). SU-E-T-774: on the Effects of Intrafraction Motion on TomoTherapy SIB Treatments of Lung Tumors: A 4D Monte Carlo Study including Non-Rigid Registration and Beamlet-Breathing Phase Correlation. Medical Physics, 38(6 Part35), 3669. https://doi.org/10.1118/1.3612738 (Original work published 2011)
2010
Papier de conférence
Janssens, G., Petit, S., Orban de Xivry, J., Hanbeukers, B., Macq, B., van Elmpt, W., De Ruysscher, D., & Lambin, P. (2010). The concept of a ‘virtual patient’: Transformation of multiple lung cancer patients to a common spatial configuration using non-rigid registration, a way to simplify large datasets and to generate new hypotheses. Radiotherapy & Oncology, 96(Supplement 1), S92. (Original work published 2010)
Article de journal
Orban de Xivry, J., Castadot, P., Janssens, G., Lee, J., Geets, X., Grégoire, V., & Macq, B. (2010). Evaluation of the radiobiological impact of anatomic modifications during radiation therapy for head and neck cancer : can we simply summate the dose? Radiotherapy & Oncology, 96(1), 131-138. https://doi.org/10.1016/j.radonc.2010.05.009 (Original work published 2010)
Thèse
Janssens, G. (2010). Registration models for tracking organs and tumors in highly deformable anatomies : applications to radiotherapy.
2009
Article de journal
Janssens, G., Orban de Xivry, J., Fekkes, S., Dekker, A., Macq, B., Lambin, P., & van Elmpt, W. (2009). Evaluation of nonrigid registration models for interfraction dose accumulation in radiotherapy. Medical Physics, 36(9), 4268-4276. https://doi.org/10.1118/1.3194750 (Original work published 2009)
Plumat, J., Andersson, M., Janssens, G., Orban de Xivry, J., Knutsson, H., & Macq, B. (2009). Image registration using the Morphon algorithm: an ITK implementation. Insight Journal, 2009 January - June. (Original work published 2009)
Papier de conférence
van den Bogaard, J., Janssen, M., Janssens, G., Buijsen, J., Lammering, G., Reniers, B., Lambin, P., & Ollers, M. (2009). Use of advanced deformable registration algorithms in repeated fdg pet-ct imaging for rectal cancer. 10th BIENNAL ESTRO, Conference on physics and radiation technology for clinical radiotherapy., Maastricht, The Netherlands.
Janssens, G., Orban de Xivry, J., Fekkes, S., Dekker, A., Macq, B., Lambin, P., & van Elmpt, W. (2009). Validation of inter-fraction dose accumulation using non-rigid registration algorithms. 10th BIENNAL ESTRO, Conference on physics and radiation technology for clinical radiotherapy., Maastricht, The Netherlands.
Reniers, B., Janssens, G., & Verhaegen, F. (2009). 3D dose distribution for gyn with dose accumulation between insertions: feasibility study. 10th BIENNAL ESTRO, Conference on physics and radiation technology for clinical radiotherapy., Maastricht, The Netherlands.
2008
Papier de conférence
Janssens, G., Orban de Xivry, J., Aerts, H. J. W. L., Bosmans, G., Dekker, A. L. A., & Macq, B. (2008). Improving physical behavior in image registration. 2008 15th IEEE International Conference on Image Processing - ICIP 2008, p. 2952-2955. https://doi.org/10.1109/ICIP.2008.4712414
2007
Article de journal
Orban de Xivry, J., Janssens, G., Bosmans, G., De Craene, M., Dekker, A., Buijsen, J., van Baardwijk, A., De Ruysscher, D., Macq, B., & Lambin, P. (2007). Tumour delineation and cumulative dose computation in radiotherapy based on deformable registration of respiratory correlated CT images of lung cancer patients. Radiotherapy & Oncology, 85(2), 232-238. https://doi.org/10.1016/j.radonc.2007.08.012 (Original work published 2007)
2006
Papier de conférence
Janssens, G., Orban de Xivry, J., Bosmans, G., Buijsen, J., Decraene, M., Dekker, A., van Baardwijk, A., Macq, B., & Lambin, P. (2006). Semi-automatic delineation of moving lung tumours using deformation fields based on respiration correlated CT: Improvement of the internal target volume definition. Radiotherapy & Oncology, 81, S98-S98. (Original work published 2006)
Orban de Xivry, J., Janssens, G., Bosmans, G., Buijsen, J., De Craene, M., Dekker, A., Van Baardwijk, A., Lambin, P., & Macq, B. (2006). Deformation of planned dose distribution to track delivered dose to Non Small Cell Lung Cancer (NSCLC) patients. Radiotherapy & Oncology, 81(Supplement 1), S102. (Original work published 2006)