14:30
16/10/2026 - 14:30 - ISBA C115 -
Will give a presentation on :
Abstract:
Platform trials are a new class of clinical study design that allow treatment arms to enter and leave the trial over time and have proven to be particularly popular during the COVID-19 pandemic where no fewer than 58 trials have been registered as a platform trial. A common feature of these designs is the desire to answer several research questions within a single protocol. One of the questions arising from this feature that has generated a lot of discussion in the literature is the need for (or lack of need to) control error rates as well as the most appropriate type of error control.
In this talk I will begin by reflecting on the discussion around error rates and introduce different possible testing strategies that could be considered for platform trials. Throughout this presentation I will highlight areas where further research is necessary to enable platform trials to unleash their full potential.