December 04, 2023
Monday December 4, 2023 – 1pm – Auditoire Maisin - LDRI Seminar
Dendritic cells in tumors: which subpopulations to use for novel cancer therapies?
Prof. Damya LAOUI
Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
Lab of Dendritic Cell Biology and Cancer Immunotherapy, VIB Center for Inflammation Research, Brussels, Belgium.
Related publications :
- Clappaert EJ, Kancheva K, Brughmans J, Debraekeleer A, Bardet PMR, Elkrim Y, Lacroix D, Živalj M, Hamouda AEI, Van Ginderachter JA, Deschoemaeker S, Laoui D. Flt3L therapy increases the abundance of Treg-promoting CCR7 + cDCs in preclinical cancer models. Front Immunol. 2023 Aug 9;14:1166180.
- Murgaski A, Kiss M, Van Damme H, Kancheva D, Vanmeerbeek I, KeirsseJ, Hadadi E, Brughmans J, Arnouk SM, Hamouda AEI, Debraekeleer A, Bosteels V, ElkimY, Boon L, Hoves S, Vandamme N, Deschoemaeker S, Janssens S, Garg AD, Vande Velde G, Schmittnägel M, Ries CH, Laoui D. Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages. Cancer Research. 2022 Oct 17;82(20):3785-3801.
- Laoui D, Keirsse J, Morias Y, Van Overmeire E, Geeraerts X, Elkrim Y, Kiss M, Bolli E, Lahmar Q, Sichien D, Serneels J, Scott CL, Boon L, De Baetselier P, Mazzone M, Guilliams M, Van Ginderachter JA. The tumour microenvironment harbours ontogenically distinct dendritic cell populations with opposing effects on tumour immunity. Nature Communications. 2016 Dec 23;7:13720.