Steven DE SOIR - Translational Research from Experimental and Clinical Pharmacology to Treatment Optimization (TFAR)/ Cellular and Molecular Pharmacology (FACM)
Exploring Phage-Antibiotic Synergies for the Treatment of Biofilm-related Infectious Diseases
Promotors: Prof. Françoise Van Bambeke and Prof. Jean-Paul Pirnay
Related references:
- De Soir S, Parée H, Kamarudin NHN, Wagemans J, Lavigne R, Braem A, Merabishvili M, De Vos D, Pirnay J, Van Bambeke F. 2024. Exploiting phage-antibiotic synergies to disrupt Pseudomonas aeruginosa PAO1 biofilms in the context of orthopedic infections. Microbiol Spectr 12:e03219-23. (https://doi.org/10.1128/spectrum.03219-23)
- Wang Z & De Soir S., Glorieux A, Merabishvili M, Knoop C, De Vos D, Pirnay J, Van Bambeke F. Phages as potential antibiotic potentiators in cystic fibrosis: Study of combinations of antibiotics with a phage cocktail targeting dual species biofilms of S. aureus and P. aeruginosa
- Steele A, Stacey HJ, De Soir S, Jones JD. The Safety and Efficacy of Phage Therapy for Superficial Bacterial Infections: A Systematic Review. Antibiotics (Basel). 2020 Oct 29;9(11):754. doi: 10.3390/antibiotics9110754. PMID: 33138253; PMCID: PMC7692203
- Clarke AL, De Soir S, Jones JD. The Safety and Efficacy of Phage Therapy for Bone and Joint Infections: A Systematic Review. Antibiotics (Basel). 2020 Nov 10;9(11):795. doi: 10.3390/antibiotics9110795. PMID: 33182795; PMCID: PMC7697170
- Stacey HJ, De Soir S, Jones JD. The Safety and Efficacy of Phage Therapy: A Systematic Review of Clinical and Safety Trials. Antibiotics (Basel). 2022 Sep 30;11(10):1340. doi: 10.3390/antibiotics11101340. PMID: 36289998; PMCID: PMC9598614
This thesis defence took place on February 29, 2024.
