Justine GILLARD - Thesis defence

Justine GILLARD - IREC and LDRI/Metabolism and Nutrition (MNut)

Bile acids and the enterohepatic cycle: from old dogmas to new potential therapeutic targets for non-alcoholic steatohepatitis

Promotor: Prof. Isabelle Leclercq - Copromotor : Prof. Laure Bindels

Related references:

• Gillard J, Clerbaux LA, Nachit M, Sempoux C, Staels B, Bindels LB, Tailleux A, Leclercq IA. Bile acids contribute to the development of non-alcoholic steatohepatitis in mice. JHEP Reports. 2022;4:100387.
• Gillard J, Picalausa C, Ullmer C, Adorini L, Staels B, Tailleux A, Leclercq IA. Enterohepatic Takeda G-Protein Coupled Receptor 5 Agonism in Metabolic Dysfunction-Associated Fatty Liver Disease and Related Glucose Dysmetabolism. Nutrients. 2022;14:2707.
• Gillard J, Leclercq IA. Biological tuners to reshape the bile acid pool for therapeutic purposes in non-alcoholic fatty liver disease. Clinical Science. 2023; 137:65-85.

This thesis defence took place on April 25, 2023.