Advanced Drug Delivery and Biomaterials (ADDB)
ldri | Bruxelles Woluwe
The aim of the research of the Advanced Drug Delivery and Biomaterials research group is to develop new delivery systems for unmet medical and pharmaceutical needs that address two main challenges for the pharmaceutical industry.
Figure 1: A. Drug delivery systems and biomaterials developed/used by the ADDB group; B. Biomedical applications
The objective of our research is to use drug delivery systems and biomaterials as a mean to improve therapeutic outcomes of drugs. We develop drug delivery systems going from nano-scale, through micro-scale up to macro-scale (Figure 1A).
Our different research applications can be gathered into two research themes (Figure 1B):
1. Nanomedicines:
a. Cancer: this theme focuses on targeted theranostic nanoparticles loaded with anticancer drugs or siRNA, adjuvanted recombinant antigens and gene vaccines.
b. Mucosal delivery routes: this theme includes the research on oral delivery using nanomedicines, cutaneous delivery and pulmonary delivery.
c. CNS diseases: the objective is to develop nanomedicines that would stimulate CNS repair by local, systemic, or mucosal delivery.
2. Regenerative medicine: this theme focuses on tissue regeneration and restoration and gathers the research on spinal cord regeneration, dental restoration and skin wound healing.