Applied Statistics Workshop by Marina Vives

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LIDAM Statistics Seminar by Ivan Kojadinovic

27/11/2026 - 11:00 - ISBA C115 - 
 

Ivan Kojadinovic  

(Université de Pau et des Pays de l'Adour) 

Will give a presentation on : 

An algorithmic procedure for solving the generalized minimum information checkerboard copula problem

Abstract: 
The minimum information copula principle (see Meeuwissen and Bedford, 1997) is a maximum entropy-like approach for finding the least informative copula that satisfies a certain number of expectation constraints specified either from expert knowledge or the available limited data. In this presentation, we first propose a generalization of this principle allowing the inclusion of additional constraints fixing certain higher-order margins of the copula. We next prove that the associated optimization problem has a unique solution under a natural condition. As the latter problem is intractable in general, following the existing literature, we consider its version with all the probability measures involved in its formulation replaced by checkerboard approximations. This amounts to attempting to solve a
so-called discrete I-projection linear problem. We then use the seminal results of Csiszar (1975) to derive an IPFP-like procedure for solving the latter and provide theoretical guarantees for its convergence. We next report numerical experiments in dimensions up to four with substantially finer discretizations than those encountered in the literature. We finally discuss the computational cost of the procedure and hint at memory saving implementations that should allow to tackle higher dimensional problems under certain conditions.

Applied Statistics Workshop by Aurelie Bertrand and Laura Symul

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LIDAM Statistics Seminar by Alessandra Luati

11/12/2026 - 14:30 - ISBA C115 - 
 

Alessandra Luati  

(Imperial College London) 

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LIDAM Statistics Seminar by Kellie Archer

13/11/2026 - 14:30 - ISBA C.115 - 
 

Kellie Archer 

(The Ohio State University) 

Will give a presentation on : 

High-Dimensional Mixture Cure Models for Time-to-Event Data 

Abstract: 
Medical breakthroughs in recent decades have led to cures for many diseases including cancer.  For example, various groups have shown that advances in therapy for leukemia and myelodysplastic syndrome have increased overall survival rates and some groups have identified factors related to long-term survival, defined as survival exceeding three years, which included that patients treated on newer treatment regimens were more likely to be long-term survivors. In fact, some argue that these improved outcomes indicate that some AML patients can be considered “potentially cured.” The mixture cure model (MCM) is a time-to-event model that is used when a cured fraction exists. MCMs assume the population consists of two subgroups, those cured will not experience the event of interest and those susceptible to the event of interest. Therefore, “cured” can be considered synonymous with attaining long-term relapse-free survival. Thus, there are two regression components in MCMs which permit identification of features associated with cure and/or latency of susceptible patients. Many researchers have sought to identify a prognostic model for a time-to-event outcome. When the covariate space is high-dimensional, as in the case with gene expression data, typically penalized Cox proportional hazards (PH) models are fit. However, when a dataset includes a cured fraction, MCMs are more appropriate than Cox PH models. In these scenarios, Cox models often yield inaccurate hazard and survival estimates due to violations of the proportional hazards assumption. Despite their utility, robust methods for fitting MCMs to high-dimensional data remain scarce. In this talk, I will present our recent work extending MCMs to effectively handle high-dimensional covariate spaces, offering a more accurate prognostic tool for modern high-dimensional datasets.

LIDAM Statistics Seminar by Debarghya Ghoshdastidar

26/02/2027 - 14:30 - ISBA C115 - 
 

Debarghya Ghoshdastidar

(Technical University of Munich) 

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LIDAM Statistics Seminar by Emilie Devijver

05/03/2027 - 14:30 - ISBA C115 - 
 

Emilie Devijver

(Université Grenoble Alpes) 

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