Céline SCHOONJANS - Thesis defence

Tumor microenvironment involvement in the metabolic reprogramming induced by the PDK inhibitor dichloroacetate

Céline SCHOONJANS - REMA (Biomedical Magnetic Resonance), LDRI, UCL and FATH (Pharmacologie et Thérapeutique), IREC, UCL

Supervisors : Bernard Gallez (promotor) and Olivier Feron (co-promotor)

Related publications :

• Schoonjans, C. A., Joudiou, N., Brusa, D., Corbet, C., Feron, O., & Gallez, B. (2020). Acidosis-induced metabolic reprogramming in tumor cells enhances the anti-proliferative activity of the PDK inhibitor dichloroacetate. Cancer Letters, 470, 18-28.
• Schoonjans, C. A., Mathieu, B., Joudiou, N., Zampieri, L. X., Brusa, D., Sonveaux, P., ... & Gallez, B. (2020). Targeting Endothelial Cell Metabolism by Inhibition of Pyruvate Dehydrogenase Kinase and Glutaminase-1. Journal of clinical medicine, 9(10), 3308.
• Schoonjans, C. A., & Gallez, B. (2020). Metabolic Plasticity of Tumor Cells: How They Do Adapt to Food Deprivation. In Tumor Microenvironment (pp. 109-123). Springer, Cham.

The thesis defence took place on December 18, 2020