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Theses

ldri | Bruxelles Woluwe

THESES IN PROGRESS

Ameraoui Hafsa
Contribution to the study of oxysterols in inflammatory bowel diseases: from their quantification in patients to the study of their properties in vitro and in vivo.
Director: Giulio Muccioli

Deltombe Matthieu
The role of extracellular vesicle-associated miRNAs in the pathophysiology of multiple sclerosis.
Director: Vincent van Pesch; Co-director: Giulio Muccioli

Hoflack Laurie
Development and pharmacological assessment of a dual nanocarrier containing pro-resolutive drugs in models of rheumatoid arthritis
Directors : Mireille Al Houayek and Ana Beloqui Garcia

Kouakou Axell-Natalie
Study of the links between obesity, gut microbiota and melanoma progression and response to therapy.
Directors: Bénédcite Jordan, Patrice D. Cani, Giulio Muccioli

Laghouati Adam
Study of the involvement of the endocannabinoid system in the resolution of inflammation.
Directors: Mireille Al Houayek

Leloup Romane
GPR183 et ses ligands en tant que modulateurs de l'inflammation du tissus adipeux durant l'obésité.
Director: Giulio Muccioli

Martin Lisa
Involvement of the endocannabinoid system in the resolution of post-operative pain
Director: Mireille Al Houayek; Co-director: Giulio Muccioli

Navarro David
Impact of obesity on the metastatic potential of ovarian cancer toward the peritoneal cavity
Directors: Mireille Al Houayek and Bénédicte Jordan

Temperman Elsa
Inhibiting ABHD6 as anti-inflammatory strategy in the context of chronic lung inflammation
Director: Giulio Muccioli

Terrasi Romano
Development and validation of an MS/MS method to quantify phospholipids and lysophospholipids.
Director: Giulio Muccioli

van Nedervelde Louise
cGAS STING silencing using targeted nanomedicines to alleviate neuroinflammation in the scope of spinal cord injury and promote functional recovery
Directors : Anne des Rieux and Giulio Muccioli

Wijma Yvonne
Assessing the potential of prostamides and prostaglandin glycerol esters in modulating glial cells
Director: Mireille Al Houayek

Yagoubi Hafsa
Effect of MAGL inhibition on the process of inflammation resolution in obesity
Director: Mireille Al Houayek

Zuccaro Noemi
Director: Mireille Al Houayek

Auquière Marie
Investigating bioactive lipid- and microRNA-loaded extracellular vesicles to target neuroinflammation
Director: Anne des Rieux (ADDB/LDRI); co-director: Giulio Muccioli (BPBL/LDRI)
2026.

Ma Zhanjun
MicroRNA-124 loaded lipid nanoparticles for the treatment of spinal cord injury
Director: Anne des Rieux; co-director: Giulio Muccioli
2026.

Morelle Axel
Synthesis and pharmacological evaluation of lactams as Fatty Acid Amide Hydrolase inhibitors
Directors: Raphaël Robiette and Giulio Muccioli
2025.

Paquot Adrien
Setting up, validation and application of lipid quantification methods : a powerful tool to study inflammatory diseases : the examples of prostaglandins and short chain fatty acids
Director: Giulio Muccioli
2024.

Roumain Martin
Advances in bioactive sterol research : metabolism and quantification of oxysterols and bile acids
Director: Giulio Muccioli
2024.

Mwema Ariane
Nose-to-brain delivery of nanomedicines to stimulate remyelination in the scope of multiple sclerosis.
Director: Anne des Rieux; Co-director: Giulio Muccioli
2023.

Abdul Khalik Hafiz
Evaluation of the potential of Pakistani plants used in traditional medicine for the treatment of inflammatory bowel diseases (IBD) and identification of their active molecules
Director: Joelle Quetin-Leclercq; Co-Director: Giulio Muccioli
2022.

Labrak Yasmine
Targeted nanomedicines to stimulate the differentiation of oligodendrocyte progenitor cells in the scope of multiple sclerosis.
2022. With Anne des Rieux

Bottemanne Pauline
Study of the role of N-acylethanolamine-hydrolyzing acid amidase (NAAA) in inflammation and models of neurodegenerative diseases.
2020. With Mireille Al Houayek

Buisseret Baptiste
Study of the effects of oxygenated derivatives of endocannabinoids in inflammation and inflammatory pain.
2020. With Mireille Al Houayek

Guillemot-Legris Owein
Central nervous system inflammation in the context of obesity: implication of bioactive lipids and pathophysiological repercussions.
2017.

Masquelier Julien
Targeted and untargeted lipidomics studies: towards a better understanding of the role of lipids in inflammation.
2017.

Mutemberezi Valentin
Setting up of quantification methods for oxysterols and their metabolites: Towards a better understanding of their role in inflammation.
2017.

Al Houayek Mireille
Controlling inflammation and macrophage activation with bioactive lipids: Role of PEA and 2-AG metabolizing enzymes.
2014. With Didier Lambert as co-promotor (UCLouvain).