Biological Imaging (IMABIOL)

Picture credit : Yvan Flamant - IMABIOL

High-resolution imaging equipment for biological samples
Light and scanning microscopy
Cell sorter
Expertise available from qualified personnel for both light microscopy and nanoscopy

Confocal microscopy
- NEW !!! LEICA STELLARIS 8 FALCON - 3D images and capture of dynamic processes in real-time
- Zeiss LSM980 with six laser lines (405, 445, 488, 514, 561, 663), Airyscan II/Multiplex, Definite focus 2
- Thermostatic chamber
Epifluorescence microscopy
- Two Observer Z1 inverted stand microscopes (Zeiss)
- Bright field-Phase contrast-ICD-Fluorescence
- Motorised stage
- Zen Module Tiles/Positions
- CellASIC ONIX 2 microfluidic system
Atomic force microscopy
- Bioscope Resolve, NanoWizard III, Nanowizard IV coupled to an Observer Z1 inverted stand microscope (Zeiss)
- Bioscope Resolve coupled to a LSM980
- Fluid-FM technology and UltraSpeed NW head
- Autonomous AFM : force robot with automatic force mapping and temperature control from 4°C to 50°C
Flow cytometry
- One fluorescence-activated cell sorter: Cell Sorter S3e Biorad

Get an overview of the platform’s facilities via a virtual tour.

Confocal microscopy allows for the determination of the cellular and subcellular localisation of proteins and biomolecules at high resolution, and the monitoring of their dynamics. Furthermore, combined with appropriate software, it is possible to obtain quantitative data on the molecule of interest.
Atomic force microscopy (AFM) has recently opened up a range of new possibilities for imaging and manipulating cell surfaces in their natural environment, complementing optical imaging techniques. It allows for the visualisation of cell surface structure at nanoscale resolution and under physiological conditions, and gives researchers the ability to localise unique receptors on the cell surface and quantitatively probe cellular interactions.

12 June 2023

IMABIOL is now equipped with a new state-of-the-art microscope to provide a better view of the complexity of life at cellular and molecular levels

The IMABIOL platform has just acquired a new confocal microscope: the LEICA STELLARIS 8 FALCON*. With unmatched resolution, speed, and sensitivity, this cutting-edge microscope is designed to capture the finest details of your specimens, giving you a bird's eye view of the intricacies of life at the cellular and molecular levels.
12 May 2022

AFM: an ally to reach the frontiers of nanotechnology, biophysics and biology

David Alsteens is the head of the team that has just made this very promising discovery in the health field. He has been working on it for several years. His aim is to investigate the molecular mechanisms. His most valuable ally (apart from his team)? The atomic force microscope.

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