IBST
Croix du sud 4-5/L7.07.10
1348 Louvain-la-Neuve
Frédéric Clotman
Professeur
Directeur de recherche FNRS
- Diploma
Year Label Educational Organization 1989 Candidat en sciences pour le groupe des sciences biologiques Université catholique de Louvain 1991 Licencie en sciences (groupe des sciences zoologiques) Université catholique de Louvain 1994 Diplômé d'études approfondies en biologie Université catholique de Louvain 1996 Docteur en sciences Université catholique de Louvain
Molecular and cellular mechanisms controlling neuronal differentiation and migration during development of the spinal cord.
Neuroplasticity of spinal interneurons after adult spinal cord injury.
Contribution of spinal interneurons to the etiopathogenesis of Amyotrophic Lateral Sclerosis.
2024
Renaux, Estelle ; Baudouin, Charlotte ; Schakman, Olivier ; Gay, Ondine ; Martin, Manon ; Marchese, Damien ; Achouri, Younes ; Rezsohazy, René ; Gofflot, Françoise ; Clotman, Frédéric. Arid3c identifies an uncharacterized subpopulation of V2 interneurons during embryonic spinal cord development. In: Frontiers in Cellular Neuroscience, Vol. 18, no.None, p. Published online (2024). doi:10.3389/fncel.2024.1466056.
2024
Zupančič, Maja ; Keimpema, Erik ; Tretiakov, Evgenii O. ; Eder, Stephanie J. ; Lev, Itamar ; Englmaier, Lukas ; Bhandari, Pradeep ; Fietz, Simone A. ; Härtig, Wolfgang ; Renaux, Estelle ; Villunger, Andreas ; Hökfelt, Tomas ; Zimmer, Manuel ; Clotman, Frédéric ; Harkany, Tibor. Concerted transcriptional regulation of the morphogenesis of hypothalamic neurons by ONECUT3. In: Nature Communications, Vol. 15, no.1, p. Published online (2024). doi:10.1038/s41467-024-52762-z.
2024
Renaux, Estelle ; Baudouin, Charlotte ; Marchese, Damien ; Clovis, Yoanne ; Lee, Soo-Kyung ; Gofflot, Françoise ; Rezsohazy, René ; Clotman, Frédéric. Lhx4 surpasses its paralog Lhx3 in promoting the differentiation of spinal V2a interneurons. In: Cellular and Molecular Life Sciences, Vol. 81, no.1, p. Published online (2024). doi:10.1007/s00018-024-05316-x.
2024
Dominguez Bajo, Ana ; Clotman, Frédéric. Potential Roles of Specific Subclasses of Premotor Interneurons in Spinal Cord Function Recovery after Traumatic Spinal Cord Injury in Adults. In: Cells, Vol. 13, no.8, p. 652 (2024). doi:10.3390/cells13080652.
2024
Goffin, Luca ; Lemoine, Damien ; Clotman, Frédéric. Potential contribution of spinal interneurons to the etiopathogenesis of amyotrophic lateral sclerosis. In: Frontiers in Neuroscience, Vol. 18, no.None, p. Published online (2024). doi:10.3389/fnins.2024.1434404.
2023
Zupančič, Maja ; Tretiakov, Evgenii ; Máté, Zoltán ; Erdélyi, Ferenc ; Szabó, Gábor ; Clotman, Frédéric ; Hökfelt, Tomas ; Harkany, Tibor ; Keimpema, Erik. Brain‐wide mapping of efferent projections of glutamatergic (Onecut3+) neurons in the lateral mouse hypothalamus. In: Acta Physiologica, Vol. 238, no.3, p. 1 (2023). doi:10.1111/apha.13973.
2021
Baudouin, Charlotte ; Pelosi, Barbara ; Courtoy, Guillaume E ; Achouri, Younes ; Clotman, Frédéric. Generation and characterization of a tamoxifen-inducible Vsx1-CreER line to target V2 interneurons in the mouse developing spinal cord.. In: Genesis: The Journal of Genetics and Development, , p. e23435 (2021). doi:10.1002/dvg.23435 (Accepté/Sous presse).
2020
Gray de Cristoforis, Angelica ; Ferrari, Francesco ; Clotman, Frédéric ; Vogel, Tanja. Differentiation and localization of interneurons in the developing spinal cord depends on DOT1L expression.. In: Molecular Brain, Vol. 13, no.1, p. 85 (2020). doi:10.1186/s13041-020-00623-3.
2020
Romanov, Roman A ; Tretiakov, Evgenii O ; Kastriti, Maria Eleni ; Zupancic, Maja ; Häring, Martin ; Korchynska, Solomiia ; Popadin, Konstantin ; Benevento, Marco ; Rebernik, Patrick ; Lallemend, Francois ; Nishimori, Katsuhiko ; Clotman, Frédéric ; Andrews, William D ; Parnavelas, John G ; Farlik, Matthias ; Bock, Christoph ; Adameyko, Igor ; Hökfelt, Tomas ; Keimpema, Erik ; Harkany, Tibor. Molecular design of hypothalamus development.. In: Nature, Vol. 582, no. 7811, p. 246-252 (2020). doi:10.1038/s41586-020-2266-0 (Accepté/Sous presse).
2020
Toch, Mathilde ; Harris, Audrey ; Schakman, Olivier ; Kondratskaya, Elena ; Boulland, Jean-Luc ; Dauguet, Nicolas ; Debrulle, Stéphanie ; Baudouin, Charlotte ; Hidalgo-Figueroa, Maria ; Gow, Alexander ; Glover, Joel C ; Tissir, Fadel ; Clotman, Frédéric. Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.. In: Scientific reports, Vol. 10, no. 1, p. 996 [1-17] (2020). doi:10.1038/s41598-020-57945-4.
2019
Toch, Mathilde ; Clotman, Frédéric. CBP and p300 coactivators contribute to the maintenance of Isl1 expression by the Onecut transcription factors in embryonic spinal motor neurons.. In: Molecular and Cellular Neuroscience, Vol. 101, p. 103411 (2019). doi:10.1016/j.mcn.2019.103411 (Accepté/Sous presse).
2019
Harris, Audrey ; Masgutova, Gauhar ; Collin, Amandine ; Toch, Mathilde ; Hidalgo-Figueroa, Maria ; Jacob, Benvenuto ; Corcoran, Lynn M. ; Francius, Cédric ; Clotman, Frédéric. Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord. In: Frontiers in Cellular Neuroscience, Vol. 13, no.184, p. 1 (2019). doi:10.3389/fncel.2019.00184.
2019
Masgutova, Gauhar ; Harris, Audrey ; Jacob, Benvenuto ; Corcoran, Lynn M ; Clotman, Frédéric. Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord.. In: Frontiers in Molecular Neuroscience, Vol. 12, p. 263 (2019). doi:10.3389/fnmol.2019.00263.
2019
Debrulle, Stéphanie ; Baudouin, Charlotte ; Hidalgo-Figueroa, Maria ; Pelosi, Barbara ; Francius, Cédric ; Rucchin, Vincent ; Ronellenfitch, Kara ; Chow, Robert L ; Tissir, Fadel ; Lee, Soo-Kyung ; Clotman, Frédéric. Vsx1 and Chx10 paralogs sequentially secure V2 interneuron identity during spinal cord development.. In: Cellular and Molecular Life Sciences, (2019). doi:10.1007/s00018-019-03408-7 (Accepté/Sous presse).
2018
Clotman, Frédéric ; Tissir, Fadel. Guidance of motor axons: where do we stand?. In: Current Opinion in Physiology, Vol. 4, p. 76-81 (2018). doi:10.1016/j.cophys.2018.06.004.
2017
Kabayiza, Uwantege Karolina ; Masgutova, Gauhar ; Harris, Audrey ; Rucchin, Vincent ; Jacob, Benvenuto ; Clotman, Frédéric. The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development. In: Frontiers in Molecular Neuroscience, Vol. 10, no.n/A, p. n/A (2017). doi:10.3389/fnmol.2017.00157.
2016
Stanga, Serena ; Zanou, Bidossessi Nadège ; TASIAUX, Bernadette ; Contino, Sabrina ; Clotman, Frédéric ; Gailly, Philippe ; Dewachter, Ilse ; Octave, Jean-Noël ; Kienlen-Campard, Pascal. APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.. In: The FASEB Journal, Vol. 30, no. 5, p. 1696-711 (2016). doi:10.1096/fj.15-278739.
2016
Romanov, Roman A ; Zeisel, Amit ; Bakker, Joanne ; Girach, Fatima ; Hellysaz, Arash ; Tomer, Raju ; Alpár, Alán ; Mulder, Jan ; Clotman, Frédéric ; Keimpema, Erik ; Hsueh, Brian ; Crow, Ailey K ; Martens, Henrik ; Schwindling, Christian ; Calvigioni, Daniela ; Bains, Jaideep S ; Máté, Zoltán ; Szabó, Gábor ; Yanagawa, Yuchio ; Zhang, Ming-Dong ; Rendeiro, Andre ; Farlik, Matthias ; Uhlén, Mathias ; Wulff, Peer ; Bock, Christoph ; Broberger, Christian ; Deisseroth, Karl ; Hökfelt, Tomas ; Linnarsson, Sten ; Horvath, Tamas L ; Harkany, Tibor. Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.. In: Nature Neuroscience, Vol. 20, no. 2, p. 176-188 (Feb 2017). doi:10.1038/nn.4462.
2016
Francius, Cédric ; Hidalgo Figueroa, Maria ; Debrulle, Stéphanie ; Pelosi, Barbara ; Rucchin, Vincent ; Ronellenfitch, Kara ; Panayiotou, Elena ; Makrides, Neoklis ; Misra, Kamana ; Harris, Audrey ; Hassani, Hessameh ; Schakman, Olivier ; Parras, Carlos ; Xiang, Mengqing ; Malas, Stavros ; Chow, Robert L. ; Clotman, Frédéric. Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord. In: Frontiers in Molecular Neuroscience, Vol. 9, p. 145 [1-15] (2016). doi:10.3389/fnmol.2016.00145.
2015
Pirson, Marc ; Debrulle, Stéphanie ; Clippe, André ; Clotman, Frédéric ; Knoops, Bernard. Thioredoxin-2 modulates neuronal programmed cell death in the embryonic chick spinal cord in basal and target-deprived conditions.. In: PLoS One, Vol. 000, no.000, p. 1-21 (2015). doi:10.1371/journal.pone.0142280.
2014
Chai, Guoliang ; Zhou, Libing ; Manto, Mario ; Helmbacher, Françoise ; Clotman, Frédéric ; Goffinet, André ; Tissir, Fadel. Celsr3 is required in motor neurons to steer their axons in the hindlimb. In: Nature Neuroscience, Vol. 17, no. 9, p. 1171-1179 (2014). doi:10.1038/nn.3784.
2014
Francius, Cédric ; Clotman, Frédéric. Generating spinal motor neuron diversity: a long quest for neuronal identity. In: Cellular and Molecular Life Sciences, Vol. 71, no. 5, p. 813-829 (2014). doi:10.1007/s00018-013-1398-x.
2014
Francius, Cédric ; Ravassard, Philippe ; Hidalgo Figueroa, Maria ; Mallet, Jacques ; Clotman, Frédéric ; Nardelli, Jeannette. Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.. In: Developmental Neurobiology, (2014). doi:10.1002/dneu.22244.
2014
des Rieux, Anne ; De Berdt, Pauline ; Ansorena Artieda, Eduardo ; Ucakar, Bernard ; Jacobs, Damien ; Schakman, Olivier ; Audouard, Emilie ; Bouzin, Caroline ; Auhl, Dietmar ; Simón-Yarza, Teresa ; Feron, Olivier ; Blanco-Prieto, Maria J ; Carmeliet, Peter ; Bailly, Christian ; Clotman, Frédéric ; Préat, Véronique. Vascular endothelial growth factor-loaded injectable hydrogel enhances plasticity in the injured spinal cord. In: Journal of Biomedical Materials Research. Part A, Vol. 102, no. 7, p. 2345–2355 (2014). doi:10.1002/jbm.a.34915.
2013
Hermant, Pascale ; Francius, Cédric ; Clotman, Frédéric ; Michiels, Thomas. IFN-ε Is Constitutively Expressed by Cells of the Reproductive Tract and Is Inefficiently Secreted by Fibroblasts and Cell Lines.. In: PLoS One, Vol. 8, no.8, p. e71320 (2013). doi:10.1371/journal.pone.0071320.
2013
Francius, Cédric ; Harris, Audrey ; Rucchin, Vincent ; Hendricks, Timothy J ; Stam, Floor J ; Barber, Melissa ; Kurek, Dorota ; Grosveld, Frank G ; Pierani, Alessandra ; Goulding, Martyn ; Clotman, Frédéric. Identification of Multiple Subsets of Ventral Interneurons and Differential Distribution along the Rostrocaudal Axis of the Developing Spinal Cord.. In: PLoS One, Vol. 8, no.8, p. e70325 (2013). doi:10.1371/journal.pone.0070325.
2013
Panayiotou, Elena ; Panayi, Elena ; Lapathitis, George ; Francius, Cédric ; Clotman, Frédéric ; Kessaris, Nicoletta ; Richardson, William D ; Malas, Stavros. Pax6 is expressed in subsets of V0 and V2 interneurons in the ventral spinal cord in mice.. In: Gene Expression Patterns, Vol. 13, no. 8, p. 328-334 (2013). doi:10.1016/j.gep.2013.06.004.
2013
Audouard, Emilie ; Schakman, Olivier ; Ginion, Audrey ; Bertrand, Luc ; Gailly, Philippe ; Clotman, Frédéric. The Onecut transcription factor HNF-6 contributes to proper reorganization of Purkinje cells during postnatal cerebellum development. In: Molecular and Cellular Neuroscience, Vol. 56, p. 159-68 (2013). doi:10.1016/j.mcn.2013.05.001.
2012
Chakrabarty, Koushik ; Von Oerthel, Lars ; Hellemons, Anita ; Clotman, Frédéric ; Espana-Bessy, Agnès ; Groot Koerkamp, Marian ; Holstege, Frank C P ; Pasterkamp, R Jeroen ; Smidt, Marten P. Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.. In: Biology open, Vol. 1, no.8, p. 693-704 (2012). doi:10.1242/bio.20121230.
2012
Espana-Bessy, Agnès ; Clotman, Frédéric. Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.. In: Molecular and cellular neurosciences, Vol. 50, no.1, p. 93-102 (2012). doi:10.1016/j.mcn.2012.04.002.
2012
Roy, Agnès ; Francius, Cédric ; Rousso, David L ; Seuntjens, Eve ; Debruyn, Joke ; Luxenhofer, Georg ; Huber, Andrea B ; Huylebroeck, Danny ; Novitch, Bennett G ; Clotman, Frédéric. Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.. In: Development (Cambridge, England), Vol. 139, no.17, p. 3109-19 (2012). doi:10.1242/dev.078501.
2012
Audouard, Emilie ; Schakman, Olivier ; René, Frédérique ; Huettl, Rosa-Eva ; Huber, Andrea B. ; Loeffler, Jean-Philippe ; Gailly, Philippe ; Clotman, Frédéric. The Onecut Transcription Factor HNF-6 Regulates in Motor Neurons the Formation of the Neuromuscular Junctions. In: PLoS One, Vol. 7, no. 12, p. e50509 (2012). doi:10.1371/journal.pone.0050509.
2011
Espana-Bessy, Agnès ; Clotman, Frédéric. Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse. In: The Journal of Comparative Neurology, Vol. 520, no. 7, p. 1424 -1441 (2012). doi:10.1002/cne.22803.
2011
Stam, F.J. ; Hendricks, T.J. ; Zhang, J. ; Geiman, E.J. ; Francius, C. ; Labosky, P.A. ; Clotman, Frédéric ; Goulding, M.. Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. In: Development, Vol. 139, no. 1, p. 179-190 (2012). doi:10.1242/dev.071134.
2010
Francius, Cédric ; Clotman, Frédéric. Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.. In: Neuroscience, Vol. 165, no. 1, p. 116-29 (2010). doi:10.1016/j.neuroscience.2009.09.076.
2009
Antoniou, Aline ; Raynaud, Peggy ; Cordi, Sabine ; Zong, Yiwei ; Tronche, François ; Stanger, Ben ; Jacquemin, Patrick ; Pierreux, Christophe ; Clotman, Frédéric ; Lemaigre, Frédéric. Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9. In: Gastroenterology, Vol. 136, no. 7, p. 2325-33 (2009). doi:10.1053/j.gastro.2009.02.051.
2008
Clotman, Frédéric ; Libbrecht, Louis ; Killingsworth, Murray C ; Loo, Christine C K ; Roskams, Tania ; Lemaigre, Frédéric. Lack of cilia and differentiation defects in the liver of human foetuses with the Meckel syndrome. In: Liver International, Vol. 28, no. 3, p. 377-384 (2008). doi:10.1111/j.1478-3231.2007.01617.x.
2008
Margagliotti, Sabrina ; Clotman, Frédéric ; Pierreux, Christophe ; Lemoine, Pascale ; Rousseau, Guy ; Henriet, Patrick ; Lemaigre, Frédéric. Role of metalloproteinases at the onset of liver development. In: Development, Growth and Differentiation, Vol. 50, no. 5, p. 331-338 (2008). doi:10.1111/j.1440-169X.2008.01031.x.
2007
Margagliotti, Sabrina ; Clotman, Frédéric ; Pierreux, Christophe ; Beaudry, Jean-Bernard ; Jacquemin, Patrick ; Rousseau, Guy ; Lemaigre, Frédéric. The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration. In: Developmental Biology Journal, Vol. 311, no. 2, p. 579-589 (2007). doi:10.1016/j.ydbio.2007.09.013.
2006
Clotman, Frédéric ; Lemaigre, Frédéric. Control of hepatic differentiation by activin/TGFbeta signaling. In: Cell Cycle, Vol. 5, no. 2, p. 168-171 (2006). doi:10.4161/cc.5.2.2341.
2006
Veiga da Cunha, Maria ; Jacquemin, Patrick ; Delpierre, Ghislain ; Théate, Ivan ; Vertommen, Didier ; Clotman, Frédéric ; Lemaigre, Frédéric ; Devuyst, Olivier ; Van Schaftingen, Emile. Increased protein glycation in fructosamine 3-kinase-deficient mice, collab. Godfraind, Catherine. In: The Biochemical Journal, Vol. 399, no. 2, p. 257-64 (2006). doi:10.1042/BJ20060684.
2006
Pierreux, Christophe ; Poll, Aurélie V ; Kemp, Caroline R ; Clotman, Frédéric ; Maestro, Miguel A ; Cordi, Sabine ; Ferrer, Jorge ; Leyns, Luc ; Rousseau, Guy ; Lemaigre, Frédéric. The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. In: Gastroenterology, Vol. 130, no. 2, p. 532-41 (2006). doi:10.1053/j.gastro.2005.12.005.
2005
Clotman, Frédéric ; Courtoy, Pierre J. ; Jacquemin, Patrick ; Plumb-Rudewiez, Nicolas ; Pierreux, Christophe ; Van Der Smissen, Patrick ; Dietz, Harry C ; Rousseau, Guy ; Lemaigre, Frédéric. Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. In: Genes & Development, Vol. 19, no. 16, p. 1849-54 (2005). doi:10.1101/gad.340305.
2004
Briançon, Nadège ; Bailly, Alain ; Clotman, Frédéric ; Jacquemin, Patrick ; Lemaigre, Frédéric ; Weiss, Mary C. Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver. In: Journal of Biological Chemistry (Online), Vol. 279, no. 32, p. 33398-408 (2004). doi:10.1074/jbc.M405312200.
2004
Plumb-Rudewiez, Nicolas ; Clotman, Frédéric ; Strick-Marchand, Hélène ; Pierreux, Christophe ; Weiss, Mary C ; Rousseau, Guy ; Lemaigre, Frédéric. Transcription factor HNF-6/OC-1 inhibits the stimulation of the HNF-3alpha/Foxa1 gene by TGF-beta in mouse liver. In: Hepatology (Baltimore, Md.), Vol. 40, no. 6, p. 1266-74 (2004). doi:10.1002/hep.20459.
2003
Clotman, Frédéric ; Libbrecht, Louis ; Gresh, Lionel ; Yaniv, Moshe ; Roskams, Tania ; Rousseau, Guy ; Lemaigre, Frédéric. Hepatic artery malformations associated with a primary defect in intrahepatic bile duct development. In: Journal of Hepatology, Vol. 39, no. 5, p. 686-692 (2003). doi:10.1016/S0168-8278(03)00409-4.
2003
Bouzin, Caroline ; Clotman, Frédéric ; Renauld, Jean-Christophe ; Lemaigre, Frédéric ; Rousseau, Guy. The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. In: Journal of Immunology, Vol. 171, no. 3, p. 1297-1303 (2003). doi:10.4049/jimmunol.171.3.1297.
2002
Clotman, Frédéric ; Lannoy, Vincent J ; Reber, Michael ; Cereghini, Silvia ; Cassiman, David ; Jacquemin, Patrick ; Roskams, Tania ; Rousseau, Guy ; Lemaigre, Frédéric. The onecut transcription factor HNF6 is required for normal development of the biliary tract. In: Development (Cambridge, England), Vol. 129, no. 8, p. 1819-28 (2002).
2000
Clotman, Frédéric ; De Backer, O ; Boon, Thierry ; De Plaen, Etienne ; Picard, Jacques. Cell- and stage-specific expression of mage genes during mouse spermatogenesis.. In: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 11, no. 8, p. 696-9 (2000). doi:10.1007/s003350010116.
1999
Gofflot, Françoise ; Kolf-Clauw, M ; Clotman, Frédéric ; Roux, C. ; Picard, Jacques. Absence of ventral cell populations in the developing brain in a rat model of the Smith-Lemli-Opitz syndrome.. In: American Journal of Medical Genetics, Vol. 87, no. 3, p. 207-216 (1999). doi:10.1002/(SICI)1096-8628(19991126)87:3<207::AID-AJMG3>3.0.CO;2-5.
1999
Carmeliet, P ; Moons, L ; Lampugnani, M G ; Breviario, F ; Compernolle, V ; Bono, F ; Balconi, G ; Spagnuolo, R ; Oosthuyse, B ; Dewerchin, M ; Zanetti, A ; Angellilo, A ; Mattot, V ; Nuyens, D ; Lutgens, E ; Clotman, Frédéric ; de Ruiter, M C ; Gittenberger-de Groot, A ; Poelmann, R ; Lupu, F ; Herbert, J M ; Collen, D ; Dejana, E. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.. In: Cell, Vol. 98, no. 2, p. 147-57 (1999).
1998
Clotman, Frédéric ; Van Maele, Geneviève ; Picard, JJ.. All-trans-retinoic acid upregulates the expression of COUP-TFI in early-somite mouse embryos cultured in vitro. In: Neurotoxicology and Teratology, Vol. 20, no. 6, p. 591-599 (1998). doi:10.1016/S0892-0362(98)00018-X.
1998
Clotman, Frédéric ; Van Maele, Geneviève ; Chu-Wu, L ; Picard, Jacques. Structural and gene expression abnormalities induced by retinoic acid in the forebrain.. In: Reproductive toxicology (Elmsford, N.Y.), Vol. 12, no. 2, p. 169-176 (1998). doi:10.1016/S0890-6238(97)00151-2.
1997
Landry, Claire ; Clotman, Frédéric ; Hioki, Takeshi ; Oda, Hiroaki ; Picard, Jacques ; Lemaigre, Frédéric ; Rousseau, Guy. HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates to the cross-regulatory network of liver-enriched transcription factors. In: Developmental Biology Journal, Vol. 192, no. 2, p. 247-257 (1997). doi:10.1006/dbio.1997.8757.
1997
Rosen, ED ; Chan, JCY ; Idusogie, E ; Clotman, Frédéric ; Vlasuk, G ; Luther, T ; Jalbert, LR ; Albrecht, S ; Zhong, L ; Lissens, A ; Schoonjans, L ; Moons, L ; Collen, D. ; Castellino, FJ ; Carmeliet, P. Mice lacking factor VII develop normally but suffer fatal perinatal bleeding. In: Nature : international weekly journal of science, Vol. 390, no. 6657, p. 290-4 (1997). doi:10.1038/36862.
1997
Van Maele, Geneviève ; Clotman, Frédéric ; Gofflot, Françoise ; Bosschaert, Johan ; Picard, Jacques. Postimplantation mouse embryos cultured in vitro : Assessment with whole-mount immunostaining and in situ hybridization. In: The International Journal of Developmental Biology, Vol. 41, no. 2, p. 365-374 (1997).
1997
Clotman, Frédéric ; Van Maele, Geneviève ; Picard, Jacques. Retinoic acid induces a tissue-specific deletion in the expression domain of Otx2. In: Neurotoxicology and Teratology, Vol. 19, no. 3, p. 163-169 (1997). doi:10.1016/S0892-0362(97)00017-2.
1996
Van Maele, Geneviève ; Clotman, Frédéric ; Picard, Jacques. Exogenously added retinoic acid effects on expression of Otx2 and on morphology in early mouse embryos. In: Acta Scientiarum Naturalium Universitatis Normalis Hunanensis, Vol. 19, no.3, p. 47-53 (1996).
1995
Van Maele, Geneviève ; Gofflot, Françoise ; Clotman, Frédéric ; Picard, Jacques. Alterations of mouse embryonic branchial nerves and ganglia induced by ethanol. In: Neurotoxicology and Teratology, Vol. 17, no. 4, p. 497-506 (1995). doi:10.1016/0892-0362(95)00009-G.