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Avenue Hippocrate 54/B1.55.03
1200 Woluwe-Saint-Lambert
Saeid Moghassemi
Chargé de recherche FNRS
Biography:
Saeid Moghassemi is a dedicated professional who has passionately pursued his education in the field of biomedical engineering. He earned both his BSc and MSc degrees in biomedical engineering-biomaterials from the prestigious Amirkabir University of Technology. In early 2020, Saeid embarked on a new academic journey, joining the Catholic University of Louvain to pursue his Ph.D. in Biomedical and Pharmaceutical Sciences under the guidance of Prof. Christiani A. Amorim. Throughout his academic career, Saeid has demonstrated a strong commitment to advancing knowledge in his field. Saeid's research interests are diverse, with a primary focus on Novel Drug Delivery Systems, Bioprinting, Nanomedicine, and Biomaterials for Tissue Engineering applications. His work reflects a keen interest in pushing the boundaries of innovation within the intersection of engineering and healthcare. As a diligent researcher, Saeid has consistently demonstrated a high level of expertise and dedication to his chosen field. His academic achievements and research contributions showcase not only his proficiency in biomedical engineering but also his potential to make significant contributions to the scientific community. With a strong foundation in both academic and practical aspects of biomedical engineering, Saeid Moghassemi is poised to continue his journey as a dynamic professional, contributing valuable insights to the ever-evolving landscape of biomedical research.
Expertise:
My immersion in biomaterials and biomedical engineering has equipped me with a versatile skill set. I have acquired proficiency in a range of advanced physicochemical techniques, encompassing the fabrication of diverse nanoparticles and scaffolds. My expertise extends to the utilization of sophisticated characterization tools such as TEM, SEM, DLS, FTIR, HPLC, and UV-VIS. Proficient in vitro analysis, my expertise extends to cell culture techniques, various cell viability assays, and molecular techniques such as PCR, western blot, immunohistochemical analyses and ELISA. My enthusiasm extends to gaining further experience in cutting-edge areas such as organ-on-a-chip and nanobiotechnology. During my Ph.D., I pioneered a third-generation photosensitizer, leveraging my expertise in nanoparticle fabrication and photodynamic therapy. Employing mathematical modeling, I meticulously optimized nanoparticle formulation. Subsequent validation, biocompatibility assessments, and in-depth in vitro tests on PDT efficiency and cell death types culminated in ex vivo purging for ovarian fragments. A transformative internship in "Laboratory Animal Medicine and Sciences" facilitated nuanced analyses, including in vivo tests through xenografting treated tissue fragments into SCID mice, unveiling the treatment's impact on ovarian follicles. With each research year, my passion for nanobiotechnology and tissue engineering burgeons, propelling me to continually deepen my understanding and contribute meaningfully to these dynamic fields.
- Diploma
Year Label Educational Organization 2016 Master of Sciences in Biomedical Engineering Amirkabir University of Technology 2024 (missing information) Université catholique de Louvain
2025
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Nikanfar, Saba ; Ghaffari-Bohlouli, Pejman ; de Souza, Paulo Eduardo Narcizo ; Shavandi, Amin ; Azevedo, Ricardo Bentes de ; Amorim, Christiani A. Metallic-based phthalocyanine nanoemulsions for photodynamic purging of ovarian tissue in leukemia patients.. In: Colloids and surfaces. B, Biointerfaces, Vol. 245, no.-, p. 114338 (2025). doi:10.1016/j.colsurfb.2024.114338.
2024
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Andrade Amorim, Christiani. Bioprinting of a Liposomal Oxygen-Releasing Scaffold for Ovary Tissue Engineering.. In: Tissue engineering. Part A, Vol. 12, no.-, p. 0003 (2024). doi:10.1089/ten.TEA.2024.0003.
2024
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Tavares Sousa, Maria João ; Vlieghe, Hanne ; Yang, Jie ; Leon Felix, Cecibel ; Andrade Amorim, Christiani. Extracellular vesicles in nanomedicine and regenerative medicine: A review over the last decade.. In: Bioactive materials, Vol. 36, no.-, p. 126-156 (2024). doi:10.1016/j.bioactmat.2024.02.021.
2024
Grubliauskaitė, Monika ; Vlieghe, Hanne ; Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Camboni, Alessandra ; Gudlevičienė, Živilė ; Andrade Amorim, Christiani. Influence of ovarian stromal cells on human ovarian follicle growth in a 3D environment.. In: Human reproduction open, Vol. 2024, no.1, p. hoad052 (2024). doi:10.1093/hropen/hoad052.
2023
Ghaffari-Bohlouli, Pejman ; Alimoradi, Houman ; Freitas Siqueira Petri, Denise ; Moghassemi, Saeid ; Andrade Amorim, Christiani ; Nie, Lei ; Shavandi, Amin. Alleviating hypoxia through self-generating oxygen and hydrogen peroxide fluorinated chitosan: Insights from a kinetic study. In: Chemical engineering journal, Vol. 473, p. 145072 [1-19] (2023). doi:10.1016/j.cej.2023.145072.
2023
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Camboni, Alessandra ; Feron, Olivier ; Azevedo, Ricardo Bentes ; Andrade Amorim, Christiani. Ex vivo purging of cancer cells from ovarian tissue using photodynamic therapy: a novel strategy to restore fertility in leukemia patients.. In: Human reproduction open, Vol. 2023, no.2, p. hoad005 (2023). doi:10.1093/hropen/hoad005.
2023
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Jafari, Hafez ; Ghaffari-Bohlouli, Pejman ; Shavandi, Amin ; Andrade Amorim, Christiani. Liposomal oxygen-generating hydrogel for enhancing cell survival under hypoxia condition. In: Colloids and Surfaces B: Biointerfaces, Vol. 113562, p. 113562 (2023). doi:10.1016/j.colsurfb.2023.113562 (Accepté/Sous presse).
2023
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Peaucelle, Alexis ; Lucci, Carolina M ; Andrade Amorim, Christiani. Mind the mechanical strength: tailoring a 3D matrix to encapsulate isolated human preantral follicles.. In: Human reproduction open, Vol. 2023, no.2, p. hoad004 (2023). doi:10.1093/hropen/hoad004.
2023
Leonel, Ellen C R ; Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Vlieghe, Hanne ; Wyns, Christine ; Orellana, Renan ; Andrade Amorim, Christiani. New Solutions for Old Problems: How Reproductive Tissue Engineering Has Been Revolutionizing Reproductive Medicine.. In: Annals of biomedical engineering, (2023). doi:10.1007/s10439-023-03321-y (Accepté/Sous presse).
2022
Madamsetty, Vijay Sagar ; Tavakol, Shima ; Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Schneible, John D ; Fatemi, Iman ; Shirvani, Abdolsamad ; Zarrabi, Ali ; Azedi, Fereshteh ; Dehshahri, Ali ; Aghaei Afshar, Abbas ; Aghaabbasi, Kian ; Pardakhty, Abbas ; Mohammadinejad, Reza ; Kesharwani, Prashant. Chitosan: A versatile bio-platform for breast cancer theranostics.. In: Journal of controlled release, Vol. 341, p. 733-752 (2022). doi:10.1016/j.jconrel.2021.12.012.
2022
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Grubliauskaité, Monika ; Vlieghe, Hanne ; Brusa, Davide ; Andrade Amorim, Christiani. Medium supplementation can influence the human ovarian cells in vitro.. In: Journal of ovarian research, Vol. 15, no. 1, p. 137 [1-12] (2022). doi:10.1186/s13048-022-01081-2.
2022
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Azevedo, RB ; Andrade Amorim, Christiani. Nanoemulsion applications in photodynamic therapy. In: Journal of Controlled Release, Vol. 351, no.-, p. 164-173 (2022). doi:10.1016/j.jconrel.2022.09.035.
2022
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Camboni, Alessandra ; Feron, Olivier ; Azevedo, Ricardo Bentes ; Andrade Amorim, Christiani. Photodynamic therapy using OR141-loaded nanovesicles for eradication of leukemic cells from ovarian tissue.. In: Photodiagnosis and photodynamic therapy, Vol. 40, no.-, p. 103139 (2022). doi:10.1016/j.pdpdt.2022.103139.
2022
de Miranda Vasconcellos Vilela, Janice ; Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Dolmans, Marie-Madeleine ; Azevedo, Ricardo B ; Andrade Amorim, Christiani. Safety of Lavender Oil-Loaded Niosomes for In Vitro Culture and Biomedical Applications.. In: Nanomaterials, Vol. 12, no. 12, p. 1999 [1-8] (2022). doi:10.3390/nano12121999.
2022
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; de Azevedo, Ricardo Bentes ; Andrade Amorim, Christiani. Secure transplantation by tissue purging using photodynamic therapy to eradicate malignant cells.. In: Journal of photochemistry and photobiology. B, Biology, Vol. 234, p. 112546 [1-13] (2022). doi:10.1016/j.jphotobiol.2022.112546.
2021
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Shavandi, Amin ; Andrade Amorim, Christiani. A review on biomaterials for ovarian tissue engineering.. In: Acta biomaterialia, Vol. 135, no.-, p. 48-63 (2021). doi:10.1016/j.actbio.2021.08.026.
2021
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; de Souza, Paulo Eduardo Narcizo ; Azevedo, Ricardo Bentes ; Andrade Amorim, Christiani. AlPc/ZnPc-based oncological photodynamic therapy for a selective eradication of leukemic cells from ovarian tissue.. In: Photodiagnosis and photodynamic therapy, Vol. 36, no.-, p. 102555 (2021). doi:10.1016/j.pdpdt.2021.102555.
2021
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Andrade Amorim, Christiani. Evaluation of PEGylated fibrin as a three-dimensional biodegradable scaffold for ovarian tissue engineering. In: Materials Today Chemistry, Vol. 22, no.-, p. 100626 (2021). doi:10.1016/j.mtchem.2021.100626.
2021
Jafari, Hafez ; Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Zahedi, Payam ; Andrade Amorim, Christiani ; Shavandi, Amin. Ovarian Cell Encapsulation in an Enzymatically Crosslinked Silk-Based Hydrogel with Tunable Mechanical Properties. In: Gels, Vol. 7, no.3, p. 138 (2021). doi:10.3390/gels7030138.
2021
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Azevedo, Ricardo Bentes ; Feron, Olivier ; Amorim, Christiani A. Photodynamic cancer therapy using liposomes as an advanced vesicular photosensitizer delivery system.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 339, p. 75-90 (2021). doi:10.1016/j.jconrel.2021.09.024 (Accepté/Sous presse).
2019
Hakamivala, Amirhossien ; Moghassemi, Saeid ; Omidfar, Kobra. Modeling and optimization of the niosome nanovesicles using response surface methodology for delivery of insulin. In: Biomedical Physics & Engineering Express, Vol. 5, no.4, p. 045041 (2019). doi:10.1088/2057-1976/ab1c3d.
2019
Mohammadinejad, Reza ; Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Ashrafizadeh, Milad ; Dehshahri, Ali ; Pardakhty, Abbas ; Sassan, Hosseinali ; Sohrevardi, Seyed-Mojtaba ; Mandegary, Ali. Shedding light on gene therapy: Carbon dots for the minimally invasive image-guided delivery of plasmids and noncoding RNAs - A review.. In: Journal of advanced research, Vol. 18, no.18, p. 81-93 (2019). doi:10.1016/j.jare.2019.01.004.
2019
Dadashzadeh, Arezoo ; Imani, Rana ; Moghassemi, Saeid ; Omidfar, Kobra ; Abolfathi, Nabiollah. Study of hybrid alginate/gelatin hydrogel-incorporated niosomal Aloe vera capable of sustained release of Aloe vera as potential skin wound dressing. In: Polymer Bulletin, Vol. 77, no.1, p. 387-403 (2019). doi:10.1007/s00289-019-02753-8 (Soumis).
2018
Yazdi Rouholamini, Seyede Elmira ; Moghassemi, Saeid ; Maharat, Zahra ; Hakamivala, Amirhossien ; Kashanian, Susan ; Omidfar, Kobra. Effect of silibinin-loaded nano-niosomal coated with trimethyl chitosan on miRNAs expression in 2D and 3D models of T47D breast cancer cell line.. In: Artificial cells, nanomedicine, and biotechnology, Vol. 46, no.3, p. 524-535 (2018). doi:10.1080/21691401.2017.1326928.
2017
Moghassemi, Saeid ; Hadjizadeh, Afra ; Omidfar, Kobra. Formulation and Characterization of Bovine Serum Albumin-Loaded Niosome.. In: AAPS PharmSciTech, Vol. 18, no.1, p. 27-33 (2017). doi:10.1208/s12249-016-0487-1.
2017
Moghassemi, Saeid ; Hadjizadeh, Afra ; Hakamivala, Amirhossien ; Omidfar, Kobra. Growth Factor-Loaded Nano-niosomal Gel Formulation and Characterization.. In: AAPS PharmSciTech, Vol. 18, no.1, p. 34-41 (2017). doi:10.1208/s12249-016-0579-y.
2015
Moghassemi, Saeid ; Parnian, Ehsan ; Hakamivala, Amirhossien ; Darzianiazizi, Maedeh ; Vardanjani, Marzieh Mowlavi ; Kashanian, Susan ; Larijani, Bagher ; Omidfar, Kobra. Uptake and transport of insulin across intestinal membrane model using trimethyl chitosan coated insulin niosomes.. In: Materials science & engineering. C, Materials for biological applications, Vol. 46, no.-, p. 333-40 (2015). doi:10.1016/j.msec.2014.10.070.
2014
Moghassemi, Saeid ; Hadjizadeh, Afra. Nano-niosomes as nanoscale drug delivery systems: an illustrated review.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 185, p. 22-36 (2014). doi:10.1016/j.jconrel.2014.04.015.
2020
Dadashzadeh, Arezoo ; Moghassemi, Saeid ; Andrade Amorim, Christiani. A preliminary study of biodegradable PEGylated fibrin for ovary tissue engineering. 11th World Biomaterials Virtual Congress (Online, du 11/12/2020 au 15/12/2020).
2020
Moghassemi, Saeid ; Dadashzadeh, Arezoo ; Andrade Amorim, Christiani. Designing, optimization and characterization of niosomal OR141 as a novel third-generation photosensitizer for photodynamic therapy of chronic myelogenous leukemia. 11th World Biomaterials Virtual Congress (Online, du 11/12/2020 au 15/12/2020).
2015
Moghassemi, Saeid ; Hadjisadeh, A. ; Oidfar, K. . Preparation and Characterization of Drug Loaded Nano -Niosomes for Tissue Engineering applications. ICANM 2015 International Conference & Exhibition on Advanced & Nano Materials (Ottawa, Canada, du 10/08/2015 au 12/08/2015).
2023
Moghassemi, Saeid. Photodynamic therapy for ex vivo purging of malignant cells from ovarian cortex before autotransplantation, prom. : Andrade Amorim, Christiani ; Bentes de Azevedo, Ricardo, 11/12/2023.
2018
Moghassemi, Saeid. Nanoniosome as a vector of peptide agents for tissue engineering, medicine and cosmetic usages. .