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Theses REMA

ldri | Bruxelles Woluwe

Theses in progress

Mélina CARBONE
Cocktails of fungicides targeting cellular respiration: which benefits to counteract resistance to cryptogamic diseases for which risks fur human cells exposed?
Director: Bernard Gallez

Natacha DEHAEN 
Investigation of the impact of high-fat diet-induced obesity on triple-negative breast cancer metastatic potential: Insights from the gut microbiota perspective
Directors : Bénédicte Jordan, Patrice Cani (MNUT)

Madeline EL ASSAL 
AI-Driven Analysis of Multiparametric MRI for Evaluating Response to Targeted and Immune Therapies in Preclinical Melanoma Models
Directors : Bénédicte Jordan, Patrice Cani (MNUT)

Axell-Natalie KOUAKOU 
Impact of diet-induced obesity on tumor growth and response to therapy in a preclinical melanoma model
Directors : Bénédicte Jordan, Patrice Cani (MNUT), Giulio Muccioli (BPBL)

David NAVARRO SANAGUSTIN
Impact of obesity on the metastatic potential of ovarian cancer toward the peritoneal cavity
Directors : Bénédicte Jordan, Mireille Alhouayek (BPBL)

Yasmine VANDENSANDE 
Induction of a mitochondrial oxidative stress in cholangiocarcinoma to boost the sensitivity to targeted therapy
Director: Bernard Gallez

Mohammad WEHBI 
Multi-Harmonics EPR in the characterization of skin melanoma 
Director: Bernard Gallez
 

2025
Barbara Mathieu
Deciphering the role of mitochondrial ROS in radiation therapy through their direct detection in vivo
Directors: Bernard Gallez, Pierre Sonveaux
Giulia Rodella
Hyaluronic acid-conjugates for the local chemo-immunomodulation of glioblastoma
Directors: Bernard Gallez, Alessio Malfanti

2024
Chloé Buyse
Monitoring the effect of anti-cancer drugs on extracellular pH and pO2 using magnetic resonance
Director: Bernard Gallez
Jérôme Conq
Assessment of strategies for a blood-brain barrier opening in glioblastoma
Directors: Bernard Gallez, Véronique Préat

2023
Chantale Farah
Assessment of early metabolic markers of response to targeted and immune therapies using 13C magnetic resonance spectroscopy in melanoma xenografts
Directors : Bénédicte Jordan, Jean-François Beaurain
Caner Yelek
Obesity-associated alterations driving breast cancer progression: understanding the role of the gut microbiota and characterizing tumor metabolism
Directors: Bénédicte Jordan, Patrice Cani

2021
Donatienne D’Hose
Dual EPR measurement of oxygen consumption and superoxide production: principle and applications
Directors: Bernard Gallez, Bénédicte Jordan

2020
Stefania Accardio
Magnetic resonance markers of response to targeted therapies in BRAFV600E melanoma xenografts
Directors : Bénédicte Jordan, Jean-François Beaurain
Florian Gourgue
Investigation of the apelin adipokine as a potential therapeutic target for breast cancer patients in the context of obesity
Directors: Bénédicte Jordan, Patrice Cani
Céline Schoonjans
Tumor microenvironment involvement in the metabolic reprogramming induced by the PDK inhibitor dichloroacetate
Directors: Bernard Gallez, Olivier Feron

2019
Thanh Trang Cao Pham
Combined endogenous MR biomarkers to assess tumor oxygenation and response to radiation therapy
Directors: Bénédicte Jordan, Bernard Gallez
Nels Janske
Lipid nanocapsules as a theranostic tool
Directors: Laurent Lemaire, Bernard Gallez
Samantha Scheinok
Development of a new EPR tool to detect mitochondrial superoxide
Directors: Bernard Gallez, Pierre Sonveaux

2017
Céline Desmet
Dynamic changes of oxygenation in wound healing in mice diabetic models monitored by Electron Paramagnetic Resonance (EPR) oximetry
Directors: Bernard Gallez, Philippe Levêque

2016
Géraldine De Preter
Metabolic plasticity in cancer cells: involvement in the processes of proliferation and response to radiotherapy
Directors: Bernard Gallez, Pierre Sonveaux
Marie-Aline Neveu
Multi-modality imaging to assess metabolic shift in tumors
Directors: Olivie Feron, Bernard Gallez

2015
Florence Colliez
Monitoring of tumor oxygenation variations using non invasive imaging based on lipid oxygen dependent relaxation in magnetic resonance: preclinical and clinical applications
Directores: Bénédicte Jordan, Bernard Gallez
Damien Jacobs
Characterization of Wallerian degeneration by in vivo diffusion compartment imaging
Directors: Benoit Macq, Anne des Rieux, Bernard Gallez
Lionel Mignion
Markers of response to the targeting of the cholinic phenotype in experimental tumor xenografts: magnetic resonance studies
Directors: Bénédicte Jordan, Vincent Grégoire
Nathalie Schleich
Multifunctional paclitaxel/superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging
Directors: Véronique Préat, Bernard Gallez
Ly Binh An Tran
Bridging the gap between tumor hypoxia and tumor response: assessing the value of imaging biomarkers to guide hypoxia-driven interventions in radiotherapy 
Director: Bernard Gallez, Vincent Grégoire

2014
Anne-Catherine Fruytier
Evaluation of tumor hemodynamics by magnetic resonance imaging : consequence of a modulation of perfusion on chemotherapy delivery
Director: Bernard Gallez
Linda Karmani
Radiolabelled antibody-targeted gold nanoparticles for cancer imaging : effects of nanoparticle conjugation on the biological properties of the antibody and tumor targeting
Director: Bernard Gallez

2013
Pierre Danhier
Monitoring the fate of metastatic tumor cells using magnetic cell tracking approaches (MRI and EPR)
Director: Bernard Gallez, Pierre Sonveaux
Benoît Driesschaert
Radicaux stables de type trityle en tant qu’agents de contraste pour l’imagerie moléculaire par RPE : synthèse de dérivés fonctionnalisés, élaboration de conjugués peptidiques, et caractérisations physico-chimiques
Directors : Jacqueline Marchand-Brynaert, Bernard Gallez
Oussama Karroum
Association of mitogen activated protein kinase inhibitors with radiation therapy
Directors: Bénédicte Jordan, Vincent Grégoire

2012
Quentin Godechal
Development and optimization of magnetic resonance-based methods for the detection and staging of malignant melanoma : EPR imaging and high-field MRI
Directors: Bernard Gallez, Jean-François Baurain
Laurie Hamtiaux
Potentiation of endocannabinoid antitumoral properties by inhibitors of their hydrolysis
Directors: Didier Lambert, Bernard Gallez

2010
Caroline Diepart
Focus on tumor oxygen consumption : development of methods to measure oxygen consumption and evaluation of innovative co-treatment for radiotherapy
Directors: Bernard Gallez, Bénédicte Jordan
Kim Radermacher
Non invasive individual monitoring of tumor response to anti-cancer treatments : early detection of radio- and chemo-induced cell death by magnetic resonance imaging
Directors: Bernard Gallez, Bénédicte Jordan