LDRI
Avenue Mounier 73/B1.73.12
1200 Woluwe-Saint-Lambert
Rita Vanbever
Directrice de recherche FNRS
Professeure extraordinaire
2024
Wang, Zhifen ; Vanbever, Rita ; Lorent, Joseph H. ; Solis, Jessica ; Knoop, Christiane ; Van Bambeke, Françoise. Repurposing DNase I and alginate lyase to degrade the biofilm matrix of dual-species biofilms of Staphylococcus aureus and Pseudomonas aeruginosa grown in artificial sputum medium: In-vitro assessment of their activity in combination with broad-spectrum antibiotics. In: Journal of Cystic Fibrosis, Vol. Feb213, no.none, p. S1569-1993(24)00027-4 (2024). doi:10.1016/j.jcf.2024.02.012.
2023
Brancaleone, Pierre ; Delefortrie, Quentin ; Descamps, Olivier ; Weynand, Birgit ; Vanbever, Rita ; Detry, Gautier. Lipoid Pneumonia Associated with Polyethylene Glycol Chronic Aspiration.. In: American journal of respiratory and critical care medicine, no. 207 (8), p. e71–e72 (2023). doi:10.1164/rccm.202107-1692IM.
2023
Mahri, Sohaib ; Wilms, Tobias ; Hagedorm, Paul ; Guichard, Marie-Julie ; Vanvarenberg, Kevin ; Dumoulin, Mireille ; Frijlink, Henderik ; Vanbever, Rita. Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study.. In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 189, p. 106522 (2023). doi:10.1016/j.ejps.2023.106522 (Accepté/Sous presse).
2022
Liu, Xiao ; Kouassi, Kobenan ; Vanbever, Rita ; Dumoulin, Mireille. Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal and proteolytic stability of mono-PEGylated alpha-1 antitrypsin. In: Protein Science, (2022) (Accepté/Sous presse).
2022
Reynaerts, Audrey ; Vermeulen, François ; Mottais, Angélique ; Gohy, Sophie ; Lebecque, Patrick ; Frédérick, Raphaël ; Vanbever, Rita ; Leal, Teresinha. Needle-free iontophoresis-driven β-adrenergic sweat rate test.. In: Journal of cystic fibrosis, Vol. 21, no. 3, p. 407-415 (2022). doi:10.1016/j.jcf.2021.08.012.
2022
Liu, Xiao ; Vanvarenberg, Kevin ; Kouassi, Wilfried ; Mahri, Sohaib ; Vanbever, Rita. Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy. In: International Journal of Pharmaceutics, Vol. 612, p. 121355 (2022). doi:10.1016/j.ijpharm.2021.121355.
2021
Mahri, Sohaib ; Rondon, Aurélie ; Wilms, Tobias ; Bosquillon, Cynthia ; Vanbever, Rita. Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 329, p. 1054-1065 (2021). doi:10.1016/j.jconrel.2020.10.034.
2021
Loira Pastoriza, Cristina ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Machado, Maria ; Staub, Aurélie ; Lemaire, Muriel ; Renauld, Jean-Christophe ; Vanbever, Rita. Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer.. In: International journal of pharmaceutics, Vol. 600, p. 120504 (2021). doi:10.1016/j.ijpharm.2021.120504.
2021
Vanbever, Rita ; Champion, Julie. Natural and Bioinspired Carriers for Therapeutic Delivery. In: Current Opinion in Colloid & Interface Science, , p. 101533 (2021). doi:10.1016/j.cocis.2021.101533 (Accepté/Sous presse).
2021
Mahri, Sohaib ; Hardy, Eléonore ; Wilms, Tobias ; De Keersmaecker, Herlinde ; Braeckmans, Kevin ; De Smedt, Stefaan ; Bosquillon, Cynthia ; Vanbever, Rita. PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages.. In: International journal of pharmaceutics, Vol. 593, p. 120107 (2021). doi:10.1016/j.ijpharm.2020.120107.
2021
Guichard, Marie-Julie ; Wilms, Tobias ; Mahri, Sohaib ; Patil, Harshad P. ; Hoton, Delphine ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Cheou, Paméla ; Beka, Mathilde ; Marbaix, Etienne ; Leal, Teresinha ; Vanbever, Rita. PEGylation of recombinant human deoxyribonuclease I provides a long‐acting version of the mucolytic for patients with cystic fibrosis. In: Advanced therapeutics, Vol. 4, no. 2, p. 2000146 (2021). doi:10.1002/adtp.202000146.
2021
Rondon, Aurélie ; Mahri, Sohaib ; Morales‐Yanez, Francisco ; Dumoulin, Mireille ; Vanbever, Rita. Protein Engineering Strategies for Improved Pharmacokinetics. In: Advanced Functional Materials, , p. 2101633 (2021). doi:10.1002/adfm.202101633.
2020
Scarcello, Eleonora ; Lambremont, Alexia ; Vanbever, Rita ; Jacques, Pascal ; Lison, Dominique. Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese. In: PloS one, Vol. 15, no. 4, p. e0231634 [1-14] (2020). doi:10.1371/journal.pone.0231634.
2019
Diaz Iglesias, Yvan ; Wilms, Tobias ; Vanbever, Rita ; Van Bambeke, Françoise. Activity of Antibiotics against Staphylococcus aureus in an Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium.. In: Antimicrobial agents and chemotherapy, Vol. 63, no.7, p. pii: e00602-19 (2019). doi:10.1128/AAC.00602-19.
2019
Vanbever, Rita ; Loira Pastoriza, Cristina ; Dauguet, Nicolas ; Hérin, Caroline ; Ibouraadaten, Saloua ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Tyteca, Donatienne ; Huaux, François. Cationic Nanoliposomes Are Efficiently Taken up by Alveolar Macrophages but Have Little Access to Dendritic Cells and Interstitial Macrophages in the Normal and CpG-Stimulated Lungs.. In: Molecular pharmaceutics, Vol. 16, no.5, p. 2048-2059 (2019). doi:10.1021/acs.molpharmaceut.9b00033.
2019
Sironval, Violaine ; Palmai-Pallag, Mihaly ; Vanbever, Rita ; Huaux, François ; Mejia Mendoza, Jorge Humberto ; Lucas, Stéphane ; Lison, Dominique ; Van Den Brûle, Sybille. HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles. In: Particle and Fibre Toxicology, Vol. 16, p. 35 [1-12] (2019). doi:10.1186/s12989-019-0319-z.
2019
Freches, Danielle ; Rocks, Natacha ; Patil, Harshad P. ; Perrin, Fabienne ; Van Snick, Jacques ; Vanbever, Rita ; Cataldo, Didier. Preclinical evaluation of topically-administered PEGylated Fab'lung toxicity. In: International Journal of Pharmaceutcis, (2019).
2019
Tomar, Jasmine ; Tonnis, Wouter F. ; Patil, Harshad P. ; de boer, Anne H. ; Hagedoorn, Paul ; Vanbever, Rita ; Frijlink, Henderik W. ; Hinrichs, Wouter L.J.. Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination. In: Acta Pharmaceutica Sinica B, Vol. 9, no. 6, p. 1231-1240 (2019). doi:10.1016/j.apsb.2019.05.003.
2018
Tomar, Jasmine ; Patil, Harshad P ; Bracho, Gustavo ; Tonnis, Wouter F ; Frijlink, Henderik W ; Petrovsky, Nikolai ; Vanbever, Rita ; Huckriede, Anke ; Hinrichs, Wouter L J. Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 288, p. 199-211 (2018). doi:10.1016/j.jconrel.2018.09.006.
2018
Patil, Harshad Padmanabh ; Freches, Danielle ; Karmani, Linda ; Duncan, Gregg A ; Ucakar, Bernard ; Suk, Jung Soo ; Hanes, Justin ; Gallez, Bernard ; Vanbever, Rita. Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation.. In: Journal of Controlled Release, Vol. 272, p. 62-71 (2018). doi:10.1016/j.jconrel.2017.12.009.
2018
Guichard, Marie-Julie ; Kinoo, David ; Aubriot, Anne-Sophie ; Bauwens, Nathalie ; Gougué, Jordane ; Vermeulen, François ; Lebecque, Patrick ; Leal, Teresinha ; Vanbever, Rita. Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum. In: Clinical Science, Vol. 132, p. 1439-1452 (2018). doi:10.1042/cs20180315.
2018
Sironval, Violaine ; Ryelandt, Laurence ; Chaurand, Perrine ; Ibouraadaten, Saloua ; Palmai-Pallag, Mihaly ; Yakoub, Yousof ; Ucakar, Bernard ; Rose, Jérôme ; Poleunis, Claude ; Vanbever, Rita ; Marbaix, Etienne ; Lison, Dominique ; Van Den Brûle, Sybille. Respiratory hazard of Li-ion battery components: elective toxicity of lithium cobalt oxide (LiCoO2) particles in a mouse bioassay. In: Archives of Toxicology, Vol. 92, no. 5, p. 1673-1684 (2018). doi:10.1007/s00204-018-2188-x.
2017
Freches, Danielle ; Patil, Harshad Padmanabh ; Machado Franco, Maria ; Uyttenhove, Catherine ; Heywood, Sam ; Vanbever, Rita. PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.. In: International Journal of Pharmaceutics, Vol. 521, no.1-2, p. 120-129 (2017). doi:10.1016/j.ijpharm.2017.02.021.
2017
Guichard, Marie-Julie ; Leal, Teresinha ; Vanbever, Rita. PEGylation, an approach for improving the pulmonary delivery of biopharmaceuticals. In: Current Opinion in Colloid & Interface Science, Vol. 31, p. 43-50 (2017). doi:10.1016/j.cocis.2017.08.001.
2017
Guichard, Marie-Julie ; Patil, Harshad Padmanabh ; Koussoroplis, Salome Juliette ; Wattiez, Ruddy ; Leal, Teresinha ; Vanbever, Rita. Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy.. In: International Journal of Pharmaceutics, Vol. 524, no. 1-2, p. 159-167 (2017). doi:10.1016/j.ijpharm.2017.03.057.
2017
Dugernier, Jonathan ; Hesse, Michel ; Vanbever, Rita ; Depoortere, Virginie ; Roeseler, Jean ; Michotte, Jean-Bernard ; Laterre, Pierre-François ; Jamar, François ; Reychler, Gregory. SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. In: Pharmaceutical Research, Vol. 34, no. 2, p. 290-300 (2017). doi:10.1007/s11095-016-2061-7.
2017
Vanbever, Rita ; Mitragotri, Samir. Therapeutic Opportunities for Polymer-Drug Conjugates to Deliver Small Molecules and Proteins. In: Current Opinion in Colloid & Interface Science, Vol. 31, p. A1-A2 (2017). doi:10.1016/j.cocis.2017.09.006.
2016
Dugernier, Jonathan ; Reychler, Gregory ; Wittebole, Xavier ; Roeseler, Jean ; Depoortere, Virginie ; Sottiaux, Thierry ; Michotte, Jean-Bernard ; Vanbever, Rita ; Dugernier, Thierry ; Goffette, Pierre ; Docquier, Marie-Agnès ; Raftopoulos, Christian ; Hantson, Philippe ; Jamar, François ; Laterre, Pierre-François. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study.. In: Annals of Intensive Care, Vol. 6, no.1, p. 73 (2016). doi:10.1186/s13613-016-0169-x.
2016
Luo, Tian ; Loira Pastoriza, Cristina ; Patil, Harshad Padmanabh ; Ucakar, Bernard ; Muccioli, Giulio ; Bosquillon, Cynthia ; Vanbever, Rita. PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma.. In: Journal of Controlled Release, Vol. 239, p. 62-71 (2016). doi:10.1016/j.jconrel.2016.08.008.
2016
Luo, Tian ; Magnusson, J ; Préat, Véronique ; Frédérick, Raphaël ; Alexander, Cameron ; Bosquillon, Cynthia ; Vanbever, Rita. Synthesis and in vitro evaluation of polyethylene glycol paclitaxel conjugates for lung cancer therapy. In: Pharmaceutical Research, Vol. 33, no. 7, p. 1671-1681. doi:10.1007/s11095-016-1908-2.
2016
Desoubeaux, Guillaume ; Reichert, Janice M ; Sleeman, Matthew ; Reckamp, Karen L ; Ryffel, Bernhard ; Adamczewski, Jörg P ; Sweeney, Theresa D ; Vanbever, Rita ; Diot, Patrice ; Owen, Caroline A ; Page, Clive ; Lerondel, Stéphanie ; Le Pape, Alain ; Heuze-Vourc'h, Nathalie. Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France.. In: mAbs, Vol. 8, no. 6, p. 999-1009 (2016). doi:10.1080/19420862.2016.1196521.
2015
Cuvelier, Brieuc ; Eloy, Pierre ; Loira Pastoriza, Cristina ; Ucakar, Bernard ; Sanogo, Abdoul Aziz ; Dupont-Gillain, Christine C. ; Vanbever, Rita. Minimal amounts of dipalmitoylphosphatidylcholine improve aerosol performance of spray-dried temocillin powders for inhalation. In: International Journal of Pharmaceutics, Vol. 495, no. 2, p. 981-990 (2015). doi:10.1016/j.ijpharm.2015.10.019.
2014
Loira Pastoriza, Cristina ; Todoroff, Julie ; Vanbever, Rita. Delivery strategies for sustained drug release in the lungs. In: Advanced Drug Delivery Reviews, Vol. 75, p. 81-94 (2014). doi:10.1016/j.addr.2014.05.017.
2014
Ungaro, Francesca ; Vanbever, Rita. Improving the efficacy of inhaled drugs for severe lung diseases: emerging pulmonary delivery strategies.. In: Advanced Drug Delivery Reviews, Vol. 75, p. 1-2 (2014). doi:10.1016/j.addr.2014.08.001.
2014
Koussoroplis, Salomé Juliette ; Paulissen, Geneviève ; Tyteca, Donatienne ; Goldansaz, Hadi ; Todoroff, Julie ; Barilly, Céline ; Uyttenhove, Catherine ; Van Snick, Jacques ; Cataldo, Didier ; Vanbever, Rita. PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 187, no. C, p. 91-100 (2014). doi:10.1016/j.jconrel.2014.05.021.
2013
Todoroff, Julie ; Lemaire, Muriel ; Fillee, Catherine ; Jurion, Fabienne ; Renauld, Jean-Christophe ; Huygen, Kris ; Vanbever, Rita. Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice. In: PLoS One, Vol. 8, no. 5, p. e63344 [1-12] (2013). doi:10.1371/journal.pone.0063344.
2013
Koussoroplis, Salomé ; Heywood, Sam ; Uyttenhove, Catherine ; Barilly, Céline ; Van Snick, Jacques ; Vanbever, Rita. Production, purification and biological characterization of mono-PEGylated anti-IL-17A antibody fragments. In: International Journal of Pharmaceutics, Vol. 454, no. 1, p. 107-115 (2013). doi:10.1016/j.ijpharm.2013.06.077.
2013
Todoroff, Julie ; Ucakar, Bernard ; Inglese, Malory ; Vandermarliere, Sophie ; Fillee, Catherine ; Renauld, Jean-Christophe ; Huygen, Kris ; Vanbever, Rita. Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 84, no. 1, p. 40-48 (2013). doi:10.1016/j.ejpb.2012.11.020.
2012
Fernandes, Cláudia A ; Fievez, Laurence ; Neyrinck, Audrey M. ; Delzenne, Nathalie M. ; Bureau, Fabrice ; Vanbever, Rita. Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. In: Biochemical and Biophysical Research Communications, Vol. 420, no.4, p. 857-861 (2012). doi:10.1016/j.bbrc.2012.03.088.
2011
Mitragotri, Samir ; Vanbever, Rita. Converting innovative colloids into potent drug delivery carriers: Opportunities and challenges. In: Current Opinion in Colloid & Interface Science, Vol. 16, no. 3, p. 169-170 (2011). doi:10.1016/j.cocis.2011.03.002.
2011
Todoroff, Julie ; Vanbever, Rita. Fate of nanomedicines in the lungs. In: Current Opinion in Colloid & Interface Science, Vol. 16, no. 3, p. 246-254 (June 2011). doi:10.1016/j.cocis.2011.03.001.
2011
Fernandes, Cláudia A. ; Fievez, Laurence ; Ucakar, Bernard ; Neyrinck, Audrey M. ; Fillee, Catherine ; Huaux, François ; Delzenne, Nathalie M. ; Bureau, Fabrice ; Vanbever, Rita. Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice. In: American Journal of Physiology: Lung Cellular and Molecular Physiology, Vol. 300, no. 3, p. L354-L361 (2011). doi:10.1152/ajplung.00198.2010.
2010
Patton, John S ; Brain, Joseph D. ; Davies, Lee A. ; Fiegel, Jennifer ; Gumbleton, Mark ; Kim, Kwang-Jin ; Sakagami, Masahiro ; Vanbever, Rita ; Ehrhardt, Carsten. The particle has landed--characterizing the fate of inhaled pharmaceuticals. In: Journal of Aerosol Medicine and Pulmonary Drug Delivery, Vol. 23, no. Suppl 2, p. S71-87 (2010). doi:10.1089/jamp.2010.0836.
2009
Lubamba, Bob ; Lebacq, Jean ; Lebecque, Patrick ; Vanbever, Rita ; Leonard, Anissa Marie ; Wallemacq, Pierre ; Leal, Teresinha. Airway delivery of low dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice. In: American Journal of Respiratory and Critical Care Medicine, Vol. 179, no. 11, p. 1022-1028 (2009). doi:10.1164/rccm.200901-0049OC.
2009
Ducreux, Julie ; Crocker, Paul R. ; Vanbever, Rita. Analysis of sialoadhesin expression on mouse alveolar macrophages. In: Immunology Letters, Vol. 124, no. 2, p. 77-80 (2009). doi:10.1016/j.imlet.2009.04.006.
2009
Ducreux, Julie ; Tyteca, Donatienne ; Ucakar, Bernard ; Medts, Thierry ; Crocker, Paul R. ; Courtoy, Pierre J. ; Vanbever, Rita. PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages. In: Bioconjugate Chemistry, Vol. 20, no. 2, p. 295-303 (2009). doi:10.1021/bc800390g.
2009
Fernandes, Cláudia A. ; Vanbever, Rita. Preclinical models for pulmonary drug delivery. In: Expert Opinion on Drug Delivery, Vol. 6, no. 11, p. 1231-1245 (2009). doi:10.1517/17425240903241788.
2008
Minne, Antoine ; Boireau, Hélène ; Horta, Maria Joao ; Vanbever, Rita. Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, no. 3, p. 839-844 (2008). doi:10.1016/j.ejpb.2008.06.013.
2008
Minne, Antoine ; Huaux, François ; Jaworska, Joanna ; Rha, Ro-Dug ; Hamelmann, Eckard ; Vanbever, Rita. Safety evaluation of pulmonary influenza vaccination in healthy and "asthmatic" mice. In: Vaccine, Vol. 26, no. 19, p. 2360-2368 (2008). doi:10.1016/j.vaccine.2008.02.062.
2008
Ducreux, Julie ; Vanbever, Rita ; Crocker, Paul R. The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following PEGylation. In: Bioconjugate Chemistry, Vol. 19, no. 10, p. 2088-2094 (2008). doi:10.1021/bc800259z.
2007
Ducreux, Julie ; Vanbever, Rita. Crucial Biopharmaceutical Issues Facing Macromolecular Candidates for Inhalation: The Role of Macrophages in Pulmonary Protein Clearance. In: Respiratory Drug Delivery Europe, Vol. 2007, no. on-line publication, p. 31-42 (2007).
2007
Minne, Antoine ; Jaworska, J. ; Gerhold, K. ; Ahrens, B. ; Avagyan, A. ; Vanbever, Rita ; Matricardi, P. M. ; Schmidt, A. C. ; Hamelmann, E.. Intranasal delivery of whole influenza vaccine prevents subsequent allergen-induced sensitization and airway hyper-reactivity in mice. In: Clinical and Experimental Allergy, Vol. 37, no. 8, p. 1250-1258 (2007). doi:10.1111/j.1365-2222.2007.02767.x.
2007
Minne, Antoine ; Louahed, Jamila ; Mehauden, Sybille ; Baras, Benoît ; Renauld, Jean-Christophe ; Vanbever, Rita. The delivery site of a monovalent influenza vaccine within the respiratory tract impacts on the immune response. In: Immunology, Vol. 122, no. 3, p. 316-325 (2007). doi:10.1111/j.1365-2567.2007.02641.x.
2005
Vanbever, Rita. Performance-driven, pulmonary delivery of systemically acting drugs. In: Drug Discovery Today: Technologies, Vol. 2, no. 1, p. 39-46 (2005). doi:10.1016/j.ddtec.2005.05.016.
2005
Reychler, Gregory ; Crémers, Caroline ; Bosquillon, Cynthia ; Vanbever, Rita ; Roeseler, Jean ; Delguste, Pierre ; Liistro, Giuseppe. Étude in vitro de deux modes de nébulisation : ventilation à percussions intrapulmonaires vs. nébulisation pneumatique. In: Kinésithérapie : la revue, Vol. 5, p. 38-41 (2005).
2004
Bosquillon, Cynthia ; Rouxhet, Paul ; Ahimou, François ; Simon, Denis ; Culot, Christine ; Préat, Véronique ; Vanbever, Rita. Aerosolization properties, surface composition and physical state of spray-dried protein powders. In: Journal of Controlled Release, Vol. 99, no. 3, p. 357-367 (2004). doi:10.1016/j.jconrel.2004.07.022.
2004
Lombry, Catherine ; Edwards, David A ; Préat, Véronique ; Vanbever, Rita. Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules. In: American Journal of Physiology: Lung Cellular and Molecular Physiology, Vol. 286, no. 5, p. L1002-L1OO8 (2004). doi:10.1152/ajplung.00260.2003.
2004
Codrons, Valérie ; Vanderbist, Francis ; Ucakar, Bernard ; Préat, Véronique ; Vanbever, Rita. Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs. In: Journal of Pharmaceutical Sciences, Vol. 93, no. 5, p. 1241-1252 (2004). doi:10.1002/jps.20053.
2004
Lombry, Catherine ; Marteleur, Aline ; Arras, Mohammed ; Lison, Dominique ; Louahed, Jamila ; Renauld, Jean-Christophe ; Préat, Véronique ; Vanbever, Rita. Local and systemic immune responses to intratracheal instillation of antigen and DNA vaccines in mice. In: Pharmaceutical Research, Vol. 21, no. 1, p. 127-135 (2004). doi:10.1023/B:PHAM.0000012160.00222.55.
2004
Bosquillon, Cynthia ; Préat, Véronique ; Vanbever, Rita. Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats. In: Journal of Controlled Release, Vol. 96, no. 2, p. 233-244 (2004). doi:10.1016/j.jconrel.2004.01.027.
2004
Denet, Anne-Rose ; Vanbever, Rita ; Préat, Véronique. Skin electroporation for transdermal and topical delivery. In: Advanced Drug Delivery Reviews, Vol. 56, no. 5, p. 659-674 (2004). doi:10.1016/j.addr.2003.10.027.
2003
Codrons, Valérie ; Vanderbist, Francis ; Verbeeck, Roger-K. ; Arras, Mohammed ; Lison, Dominique ; Préat, Véronique ; Vanbever, Rita. Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats. In: Journal of Pharmaceutical Sciences, Vol. 92, no. 5, p. 938-950 (2003). doi:10.1002/jps.10346.
2002
Lombry, Catherine ; Bosquillon, Cynthia ; Préat, Véronique ; Vanbever, Rita. Confocal imaging of rat lungs following intratracheal delivery of dry powders or solutions of fluorescent probes. In: Journal of Controlled Release, Vol. 83, no. 3, p. 331-341 (2002). doi:10.1016/S0168-3659(02)00174-8.
2001
Bosquillon, Cynthia ; Lombry, Catherine ; Préat, Véronique ; Vanbever, Rita. Comparison of particle sizing techniques in the case of inhalation dry powders. In: Journal of Pharmaceutical Sciences, Vol. 90, no. 12, p. 2032-2041 (2001). doi:10.1002/jps.1154.
2001
Bosquillon, Cynthia ; Lombry, Catherine ; Préat, Véronique ; Vanbever, Rita. Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance. In: Journal of Controlled Release, Vol. 70, no. 3, p. 329-339 (2001). doi:10.1016/S0168-3659(00)00362-X.
1999
Vanbever, Rita. Administration transdermique de médicaments par electroporation. In: Bulletin et mémoires de l'Académie royale de médecine de Belgique, Vol. 154, no. 6 Pt 2, p. 327-333 (1999).
1999
Vanbever, Rita ; Pliquett, Uwe F. ; Préat, Véronique ; Weaver, James C.. Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties. In: Journal of Controlled Release, Vol. 60, no. 1, p. 35-47 (1999). doi:10.1016/S0168-3659(99)00018-8.
1999
Zewert, Thomas E. ; Pliquett, Uwe F. ; Vanbever, Rita ; Langer, Robert ; Weaver, James C.. Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule. In: Bioelectrochemistry and Bioenergetics, Vol. 49, no. 1, p. 11-20 (1999). doi:10.1016/S0302-4598(99)00056-2.
1999
Vanbever, Rita ; Mintzes, Jeffrey D. ; Wang, Jue ; Nice, Jacquelyn ; Chen, Donghao ; Batycky, Richard ; Langer, Robert ; Edwards, David A.. Formulation and physical characterization of large porous particles for inhalation. In: Pharmaceutical Research, Vol. 16, no. 11, p. 1735-1742 (1999). doi:10.1023/A:1018910200420.
1999
Vanbever, Rita ; Préat, Véronique. In vivo efficacy and safety of skin electroporation. In: Advanced Drug Delivery Reviews, Vol. 35, no. 1, p. 77-88 (1999). doi:10.1016/S0169-409X(98)00064-7.
1999
Ben-Jebria, Abdellaziz ; Chen, Donghao ; Eskew, Mary Lou ; Vanbever, Rita ; Langer, Robert ; Edwards, David A.. Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs.. In: Pharmaceutical Research, Vol. 16, no. 4, p. 555-561 (1999). doi:10.1023/A:1018879331061.
1999
Vanbever, Rita ; Ben-Jebria, Abdellaziz ; Mintzes, Jeffrey D. ; Langer, Robert ; Edwards, David A.. Substained release of insulin from insoluble inhaled particles. In: Drug Development Research, Vol. 48, no. 4, p. 178-185 (1999). doi:10.1002/(SICI)1098-2299(199912)48:4<178::AID-DDR5>3.0.CO;2-I.
1998
Vanbever, Rita ; Fouchard, Delphine ; Jadoul, Anne ; De Morre, Nathalie ; Préat, Véronique ; Marty, Jean-Paul. In vivo noninvasive evaluation of hairless rat skin after high-voltage pulse exposure. In: Skin Pharmacology and Applied Skin Physiology, Vol. 11, no. 1, p. 23-34 (1998). doi:10.1159/000029805.
1998
Pliquett, Uwe F. ; Vanbever, Rita ; Préat, Véronique ; Weaver, James C.. Local transport regions (LTRs) in human stratum corneum due to long and short 'high voltage' pulses. In: Bioelectrochemistry and Bioenergetics, Vol. 47, no. 1, p. 151-161 (1998). doi:10.1016/S0302-4598(98)00180-9.
1998
Vanbever, Rita ; Langers, Gilles ; Montmayeur, Sonia ; Préat, Véronique. Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation. In: Journal of Controlled Release, Vol. 50, no. 1-3, p. 225-235 (1998). doi:10.1016/S0168-3659(97)00147-8.
1998
Vanbever, Rita ; Leroy, Marie-Ange ; Préat, Véronique. Transdermal permeation of neutral molecules by skin electroporation. In: Journal of Controlled Release, Vol. 54, no. 3, p. 243-250 (1998). doi:10.1016/S0168-3659(97)00146-6.
1997
Weaver, James C. ; Vanbever, Rita ; Vaughan, Timothy E. ; Prausnitz, Mark R.. Heparin alters transdermal transport associated with electroporation. In: Biochemical and Biophysical Research Communications, Vol. 234, no. 3, p. 637-640 (1997). doi:10.1006/bbrc.1997.6701.
1997
Vanbever, Rita ; Prausnitz, Mark R. ; Préat, Véronique. Macromolecules as novel transdermal transport enhancers for skin electroporation. In: Pharmaceutical Research, Vol. 14, no. 5, p. 638-644 (1997). doi:10.1023/A:1012161313701.
1996
Vanbever, Rita ; Le Boulengé, Éric ; Préat, Véronique. Transdermal delivery of fentanyl by electroporation. 1 : influence of electrical factors. In: Pharmaceutical Research, Vol. 13, no. 4, p. 559-565 (1996). doi:10.1023/A:1016093920875.
1996
Vanbever, Rita ; De Morre, Nathalie ; Préat, Véronique. Transdermal delivery of fentanyl by electroporation. 2 : mechanisms involved in drug transport. In: Pharmaceutical Research, Vol. 13, no. 9, p. 1360-1366 (1996). doi:10.1023/A:1016073917125.
1995
Vanbever, Rita ; Préat, Véronique. Factors affecting transdermal delivery of metoprolol by electroporation. In: Bioelectrochemistry and Bioenergetics, Vol. 38, no. 1, p. 223-228 (1995). doi:10.1016/0302-4598(95)01830-8.
1994
Vanbever, Rita ; Lecouturier, Nathalie ; Préat, Véronique. Transdermal delivery of metoprolol by electroporation. In: Pharmaceutical Research, Vol. 11, no. 11, p. 1657-1662 (1994). doi:10.1023/A:1018930425591.
2013
Koussoroplis, Salomé-Juliette ; Vanbever, Rita. Peptides and Proteins: Pulmonary Absorption. In: James Swarbrick, Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition, Taylor & Francis: (United Kingdom) Oxford, 2013, [1-11]. 978-1-8418-4819-8. doi:10.1081/E-EPT4-120050324.
2003
Vanbever, Rita. Optimization of dry powder aerosols for systemic drug delivery. In: Jan C.M. Marijnissen, Leon Gradon, Optimization of Aerosol Drug Delivery, Kluwer Academic Publishers: (The Netherlands) Dordrecht, 2003, p. 91-103. 1-4020-1651-4.
2002
Préat, Véronique ; Vanbever, Rita. Skin electroporation for transdermal and topical drug delivery. In: Richard H. Guy and Jonathan Hadgraft, Transdermal Drug Delivery Systems : Revised And Expanded, 2nd Edition, Informa Healthcare: (United States) Boca Raton, FL, 2002, p. 227-254. 978-0-8247-0861-0. doi:10.1201/9780203909683.ch6.
2001
Préat, Véronique ; Vanbever, Rita. Topical delivery by iontophoresis. In: Marc Paye, Andre O. Barel, Howard I. Maibach, Handbook of Cosmetic Science and Technology, 2nd Edition, Taylor & Francis Group: (United States) Boca Raton, FL, 2001, p. 211-219. 978-1-57444-824-5.
2000
Prausnitz, Mark R. ; Pliquett, Uwe ; Vanbever, Rita. Mechanistic studies of skin electroporation using biophysical methods. In: Mark J. Jaroszeski, Richard Heller, Richard Gilbert, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery : Electrically Mediated Delivery of Molecules to Cells (Methods in Molecular Medicine; 37), Humana Press: (United States) Totowa, N.J., 2000, p. 213-245. 978-0-89603-606-2. doi:10.1385/1-59259-080-2:213.
2000
Vanbever, Rita ; Préat, Véronique. Transdermal drug delivery by skin electroporation in the rat. In: Mark J. Jaroszeski, Richard Heller, Richard Gilbert, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery : Electrically Mediated Delivery of Molecules to Cells (Methods in Molecular Medicine; 37), Humana Press: (United States) Totowa, N.J., 2000, p. 457-471. 978-0-89603-606-2. doi:10.1385/1-59259-080-2:457.
2015
Dugernier, Jonathan ; Reychler, Gregory ; Wittebole, Xavier ; Roeseler, Jean ; Sottiaux , Thierry ; Michotte, Jean-Bernard ; Vanbever, Rita ; Dugernier , Thierry ; Goffette, Pierre ; Docquier, Marie-Agnès ; Raftopoulos, Christian ; Hantson, Philippe ; Jamar, François ; Laterre, Pierre-François. Lung deposition of a radiolabeled aerosol with two ventilation modalities during invasive mechanical ventilation: a randomized comparative study. 28th Annual Congress of the Society of Intensive Care Medicine (ESICM) ((Germany) Berlin, du 03/10/2015 au 07/10/2015). In: Intensive Care Medicine Experimental, Vol. 3, no.Suppl. 1 , p. A10 (2015). doi:10.1186/2197-425X-3-S1-A10.
2008
Ducreux, Julie ; Vanbever, Rita. Effect of macrophage PEGylation on endocytosis modes. Annual Meeting & Exposition of the Controlled Release Society (New-York, du 12/07/2008 au 16/07/2008).
2007
Ducreux, Julie ; Vanbever, Rita. Expression of sialoadhesin on alveolar macrophages, a macrophage-restricted receptor. International Society for Aerosols in Medicine (Tours, du 16/06/2007 au 20/06/2007).
2006
Ducreux, Julie ; Vanbever, Rita. Assessment of alveolar macrophages role in growth hormone pulmonary fate. Annual Meeting & Exposition of the Controlled Release Society (Vienne, du 22/07/2006 au 26/07/2006).
2023
DUMOULIN Mireille ; MORALES YÀNEZ Francisco ; Redeghieri, Paola ; Vanbever, Rita ; Vanderstraeten, Jessica ; Leal, Teresinha ; Mottais, Angélique ; MUYLDERMANS Serge ; VINCKE Cécile. Single-domain antibody for inhibition of neutrophil elastase activity. Déposé (30/06/2023). Belgium.
2019
Vanbever, Rita ; Koussoroplis, Salomé ; Cataldo, Didier ; Van Snick, Jacques. Method for increasing the bioavailability of inhaled compounds - US 2019/016177 A1. .
2015
Vanbever, Rita ; Koussoroplis, Salomé ; Van Snick, Jacques ; Cataldo, Didier. Method for increasing the bioavailability of inhaled compounds. Numéro de priorité ; Déposé (16/01/2015) ; Publié (23/07/2015). AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VE, VN, ZA, ZM ,ZW, ARIPO, EURASIAN, EUROPEAN, OAPI.
2012
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Particles for Inhalation Having Sustained Release Properties. Numéro de priorité ; Déposé (29/08/2011) ; Publié (03/05/2012). (United States) Cambridge, MA.
2006
Vanbever, Rita ; Langer, Robert S. ; Edwards , David A. ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao. Particles for inhalation having sustained release properties . Numéro de priorité ; Déposé (07/03/2002) ; Publié (30/05/2006). (United Staes) Cambridge, MA.
2005
Vanbever, Rita ; Edwards, David. Chemical and physical modulators of bioavailability of inhaled compositions. Numéro de priorité ; Numéro de priorité ; Numéro de priorité (2005-01-13). .
2005
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao. Particles for inhalation having sustained release properties . Numéro de priorité ; Déposé (29/12/2000) ; Publié (02/05/2005). (United States) Cambridge, MA.
2005
Chen, Donghao ; Edwards, David A. ; Evora, Carmen ; Hanes, Justin ; Langer, Robert S. ; Mintzes, Jeffrey ; Vanbever, Rita ; Wang, Jue . Preparation de particules pour inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (30/06/2005). (United States) Cambridge, MA.
2005
Chen, Donghao ; Edwards, David A. ; Evora, Carmen ; Hanes, Justin ; Langer, Robert S. ; Mintzes, Jeffrey ; Vanbever, Rita ; Wang, Jue . Preparation of particles for inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (19/01/2005). (United Staes) Cambridge, MA.
2003
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Preparation of novel particles for inhalation. Numéro de priorité ; Déposé (13/09/1999) ; Publié (25/11/2003). (United States) Cambridge, MA.
2000
Weaver, James C. ; Pliquett, Uwe ; Vanbever, Rita ; Gowrishankar, Thiruvallur R. ; Zewert, Thomas E. Biopotential measurement including electroporation of tissue surface. Numéro de priorité ; Déposé (22/05/1998) ; Publié (04/07/2000). (United Staes) Cambridge, MA.
1999
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Preparation of particles for inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (16/11/1999). (United States) Cambridge, MA.
1996
Weaver, James C. ; Chen, Tani ; Cullander, Christopher ; Guy, Richard ; Langer, Robert S. ; Zewert, Thomas E. ; Pliquett , Uwe ; Vanbever, Rita ; Prausnitz, Mark R.. Introduction of modifying agents into skin by electroporation. Numéro de priorité ; Déposé (15/06/1999) ; Publié (/). (United Staes) Cambridge, MA.