LDRI
Avenue Mounier 73/B1.73.12
1200 Woluwe-Saint-Lambert
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- Rita Vanbever
Rita Vanbever
Directrice de recherche FNRS
Professeure extraordinaire
- Les cours
Nom ID Biotechnologies WFARI2110 Eléments de physico-chimie appliqués aux médicaments WFARM1307 Etude critique d'un article de recherche en sciences pharmaceutiques WFARM2175 Présentation d'un travail de recherche en sciences pharmaceutiques WFARM2176 Séminaire d'intégration pharmaceutique (finalité approfondie) WFARM2249 Séminaire d'intégration pharmaceutique (finalité spécialisée) WFARM2259 Exercice de communication scientifique WFARM2275
Wang, Zhifen ; Vanbever, Rita ; Lorent, Joseph H. ; Solis, Jessica ; Knoop, Christiane ; Van Bambeke, Françoise. Repurposing DNase I and alginate lyase to degrade the biofilm matrix of dual-species biofilms of Staphylococcus aureus and Pseudomonas aeruginosa grown in artificial sputum medium: In-vitro assessment of their activity in combination with broad-spectrum antibiotics. In: Journal of Cystic Fibrosis, Vol. Feb213, no.none, p. S1569-1993(24)00027-4 (2024). doi:10.1016/j.jcf.2024.02.012.
Brancaleone, Pierre ; Delefortrie, Quentin ; Descamps, Olivier ; Weynand, Birgit ; Vanbever, Rita ; Detry, Gautier. Lipoid Pneumonia Associated with Polyethylene Glycol Chronic Aspiration.. In: American journal of respiratory and critical care medicine, no. 207 (8), p. e71–e72 (2023). doi:10.1164/rccm.202107-1692IM.
Mahri, Sohaib ; Wilms, Tobias ; Hagedorm, Paul ; Guichard, Marie-Julie ; Vanvarenberg, Kevin ; Dumoulin, Mireille ; Frijlink, Henderik ; Vanbever, Rita. Nebulization of PEGylated recombinant human deoxyribonuclease I using vibrating membrane nebulizers: A technical feasibility study.. In: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, Vol. 189, p. 106522 (2023). doi:10.1016/j.ejps.2023.106522 (Accepté/Sous presse).
Liu, Xiao ; Kouassi, Kobenan ; Vanbever, Rita ; Dumoulin, Mireille. Impact of the PEG length and PEGylation site on the structural, thermodynamic, thermal and proteolytic stability of mono-PEGylated alpha-1 antitrypsin. In: Protein Science, (2022) (Accepté/Sous presse).
Reynaerts, Audrey ; Vermeulen, François ; Mottais, Angélique ; Gohy, Sophie ; Lebecque, Patrick ; Frédérick, Raphaël ; Vanbever, Rita ; Leal, Teresinha. Needle-free iontophoresis-driven β-adrenergic sweat rate test.. In: Journal of cystic fibrosis, Vol. 21, no. 3, p. 407-415 (2022). doi:10.1016/j.jcf.2021.08.012.
Liu, Xiao ; Vanvarenberg, Kevin ; Kouassi, Wilfried ; Mahri, Sohaib ; Vanbever, Rita. Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy. In: International Journal of Pharmaceutics, Vol. 612, p. 121355 (2022). doi:10.1016/j.ijpharm.2021.121355.
Mahri, Sohaib ; Rondon, Aurélie ; Wilms, Tobias ; Bosquillon, Cynthia ; Vanbever, Rita. Biodistribution and elimination pathways of PEGylated recombinant human deoxyribonuclease I after pulmonary delivery in mice.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 329, p. 1054-1065 (2021). doi:10.1016/j.jconrel.2020.10.034.
Loira Pastoriza, Cristina ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Machado, Maria ; Staub, Aurélie ; Lemaire, Muriel ; Renauld, Jean-Christophe ; Vanbever, Rita. Encapsulation of a CpG oligonucleotide in cationic liposomes enhances its local antitumor activity following pulmonary delivery in a murine model of metastatic lung cancer.. In: International journal of pharmaceutics, Vol. 600, p. 120504 (2021). doi:10.1016/j.ijpharm.2021.120504.
Vanbever, Rita ; Champion, Julie. Natural and Bioinspired Carriers for Therapeutic Delivery. In: Current Opinion in Colloid & Interface Science, , p. 101533 (2021). doi:10.1016/j.cocis.2021.101533 (Accepté/Sous presse).
Mahri, Sohaib ; Hardy, Eléonore ; Wilms, Tobias ; De Keersmaecker, Herlinde ; Braeckmans, Kevin ; De Smedt, Stefaan ; Bosquillon, Cynthia ; Vanbever, Rita. PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages.. In: International journal of pharmaceutics, Vol. 593, p. 120107 (2021). doi:10.1016/j.ijpharm.2020.120107.
Guichard, Marie-Julie ; Wilms, Tobias ; Mahri, Sohaib ; Patil, Harshad P. ; Hoton, Delphine ; Ucakar, Bernard ; Vanvarenberg, Kevin ; Cheou, Paméla ; Beka, Mathilde ; Marbaix, Etienne ; Leal, Teresinha ; Vanbever, Rita. PEGylation of recombinant human deoxyribonuclease I provides a long‐acting version of the mucolytic for patients with cystic fibrosis. In: Advanced therapeutics, Vol. 4, no. 2, p. 2000146 (2021). doi:10.1002/adtp.202000146.
Rondon, Aurélie ; Mahri, Sohaib ; Morales‐Yanez, Francisco ; Dumoulin, Mireille ; Vanbever, Rita. Protein Engineering Strategies for Improved Pharmacokinetics. In: Advanced Functional Materials, , p. 2101633 (2021). doi:10.1002/adfm.202101633.
Scarcello, Eleonora ; Lambremont, Alexia ; Vanbever, Rita ; Jacques, Pascal ; Lison, Dominique. Mind your assays: Misleading cytotoxicity with the WST-1 assay in the presence of manganese. In: PloS one, Vol. 15, no. 4, p. e0231634 [1-14] (2020). doi:10.1371/journal.pone.0231634.
Diaz Iglesias, Yvan ; Wilms, Tobias ; Vanbever, Rita ; Van Bambeke, Françoise. Activity of Antibiotics against Staphylococcus aureus in an Model of Biofilms in the Context of Cystic Fibrosis: Influence of the Culture Medium.. In: Antimicrobial agents and chemotherapy, Vol. 63, no.7, p. pii: e00602-19 (2019). doi:10.1128/AAC.00602-19.
Vanbever, Rita ; Loira Pastoriza, Cristina ; Dauguet, Nicolas ; Hérin, Caroline ; Ibouraadaten, Saloua ; Vanvarenberg, Kevin ; Ucakar, Bernard ; Tyteca, Donatienne ; Huaux, François. Cationic Nanoliposomes Are Efficiently Taken up by Alveolar Macrophages but Have Little Access to Dendritic Cells and Interstitial Macrophages in the Normal and CpG-Stimulated Lungs.. In: Molecular pharmaceutics, Vol. 16, no.5, p. 2048-2059 (2019). doi:10.1021/acs.molpharmaceut.9b00033.
Sironval, Violaine ; Palmai-Pallag, Mihaly ; Vanbever, Rita ; Huaux, François ; Mejia Mendoza, Jorge Humberto ; Lucas, Stéphane ; Lison, Dominique ; Van Den Brûle, Sybille. HIF-1α is a key mediator of the lung inflammatory potential of lithium-ion battery particles. In: Particle and Fibre Toxicology, Vol. 16, p. 35 [1-12] (2019). doi:10.1186/s12989-019-0319-z.
Freches, Danielle ; Rocks, Natacha ; Patil, Harshad P. ; Perrin, Fabienne ; Van Snick, Jacques ; Vanbever, Rita ; Cataldo, Didier. Preclinical evaluation of topically-administered PEGylated Fab'lung toxicity. In: International Journal of Pharmaceutcis, (2019).
Tomar, Jasmine ; Tonnis, Wouter F. ; Patil, Harshad P. ; de boer, Anne H. ; Hagedoorn, Paul ; Vanbever, Rita ; Frijlink, Henderik W. ; Hinrichs, Wouter L.J.. Pulmonary immunization: deposition site is of minor relevance for influenza vaccination but deep lung deposition is crucial for hepatitis B vaccination. In: Acta Pharmaceutica Sinica B, Vol. 9, no. 6, p. 1231-1240 (2019). doi:10.1016/j.apsb.2019.05.003.
Tomar, Jasmine ; Patil, Harshad P ; Bracho, Gustavo ; Tonnis, Wouter F ; Frijlink, Henderik W ; Petrovsky, Nikolai ; Vanbever, Rita ; Huckriede, Anke ; Hinrichs, Wouter L J. Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 288, p. 199-211 (2018). doi:10.1016/j.jconrel.2018.09.006.
Patil, Harshad Padmanabh ; Freches, Danielle ; Karmani, Linda ; Duncan, Gregg A ; Ucakar, Bernard ; Suk, Jung Soo ; Hanes, Justin ; Gallez, Bernard ; Vanbever, Rita. Fate of PEGylated antibody fragments following delivery to the lungs: Influence of delivery site, PEG size and lung inflammation.. In: Journal of Controlled Release, Vol. 272, p. 62-71 (2018). doi:10.1016/j.jconrel.2017.12.009.
Guichard, Marie-Julie ; Kinoo, David ; Aubriot, Anne-Sophie ; Bauwens, Nathalie ; Gougué, Jordane ; Vermeulen, François ; Lebecque, Patrick ; Leal, Teresinha ; Vanbever, Rita. Impact of PEGylation on the mucolytic activity of recombinant human deoxyribonuclease I in cystic fibrosis sputum. In: Clinical Science, Vol. 132, p. 1439-1452 (2018). doi:10.1042/cs20180315.
Sironval, Violaine ; Ryelandt, Laurence ; Chaurand, Perrine ; Ibouraadaten, Saloua ; Palmai-Pallag, Mihaly ; Yakoub, Yousof ; Ucakar, Bernard ; Rose, Jérôme ; Poleunis, Claude ; Vanbever, Rita ; Marbaix, Etienne ; Lison, Dominique ; Van Den Brûle, Sybille. Respiratory hazard of Li-ion battery components: elective toxicity of lithium cobalt oxide (LiCoO2) particles in a mouse bioassay. In: Archives of Toxicology, Vol. 92, no. 5, p. 1673-1684 (2018). doi:10.1007/s00204-018-2188-x.
Freches, Danielle ; Patil, Harshad Padmanabh ; Machado Franco, Maria ; Uyttenhove, Catherine ; Heywood, Sam ; Vanbever, Rita. PEGylation prolongs the pulmonary retention of an anti-IL-17A Fab' antibody fragment after pulmonary delivery in three different species.. In: International Journal of Pharmaceutics, Vol. 521, no.1-2, p. 120-129 (2017). doi:10.1016/j.ijpharm.2017.02.021.
Guichard, Marie-Julie ; Leal, Teresinha ; Vanbever, Rita. PEGylation, an approach for improving the pulmonary delivery of biopharmaceuticals. In: Current Opinion in Colloid & Interface Science, Vol. 31, p. 43-50 (2017). doi:10.1016/j.cocis.2017.08.001.
Guichard, Marie-Julie ; Patil, Harshad Padmanabh ; Koussoroplis, Salome Juliette ; Wattiez, Ruddy ; Leal, Teresinha ; Vanbever, Rita. Production and characterization of a PEGylated derivative of recombinant human deoxyribonuclease I for cystic fibrosis therapy.. In: International Journal of Pharmaceutics, Vol. 524, no. 1-2, p. 159-167 (2017). doi:10.1016/j.ijpharm.2017.03.057.
Dugernier, Jonathan ; Hesse, Michel ; Vanbever, Rita ; Depoortere, Virginie ; Roeseler, Jean ; Michotte, Jean-Bernard ; Laterre, Pierre-François ; Jamar, François ; Reychler, Gregory. SPECT-CT Comparison of Lung Deposition using a System combining a Vibrating-mesh Nebulizer with a Valved Holding Chamber and a Conventional Jet Nebulizer: a Randomized Cross-over Study. In: Pharmaceutical Research, Vol. 34, no. 2, p. 290-300 (2017). doi:10.1007/s11095-016-2061-7.
Vanbever, Rita ; Mitragotri, Samir. Therapeutic Opportunities for Polymer-Drug Conjugates to Deliver Small Molecules and Proteins. In: Current Opinion in Colloid & Interface Science, Vol. 31, p. A1-A2 (2017). doi:10.1016/j.cocis.2017.09.006.
Dugernier, Jonathan ; Reychler, Gregory ; Wittebole, Xavier ; Roeseler, Jean ; Depoortere, Virginie ; Sottiaux, Thierry ; Michotte, Jean-Bernard ; Vanbever, Rita ; Dugernier, Thierry ; Goffette, Pierre ; Docquier, Marie-Agnès ; Raftopoulos, Christian ; Hantson, Philippe ; Jamar, François ; Laterre, Pierre-François. Aerosol delivery with two ventilation modes during mechanical ventilation: a randomized study.. In: Annals of Intensive Care, Vol. 6, no.1, p. 73 (2016). doi:10.1186/s13613-016-0169-x.
Luo, Tian ; Loira Pastoriza, Cristina ; Patil, Harshad Padmanabh ; Ucakar, Bernard ; Muccioli, Giulio ; Bosquillon, Cynthia ; Vanbever, Rita. PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma.. In: Journal of Controlled Release, Vol. 239, p. 62-71 (2016). doi:10.1016/j.jconrel.2016.08.008.
Luo, Tian ; Magnusson, J ; Préat, Véronique ; Frédérick, Raphaël ; Alexander, Cameron ; Bosquillon, Cynthia ; Vanbever, Rita. Synthesis and in vitro evaluation of polyethylene glycol paclitaxel conjugates for lung cancer therapy. In: Pharmaceutical Research, Vol. 33, no. 7, p. 1671-1681. doi:10.1007/s11095-016-1908-2.
Desoubeaux, Guillaume ; Reichert, Janice M ; Sleeman, Matthew ; Reckamp, Karen L ; Ryffel, Bernhard ; Adamczewski, Jörg P ; Sweeney, Theresa D ; Vanbever, Rita ; Diot, Patrice ; Owen, Caroline A ; Page, Clive ; Lerondel, Stéphanie ; Le Pape, Alain ; Heuze-Vourc'h, Nathalie. Therapeutic monoclonal antibodies for respiratory diseases: Current challenges and perspectives, March 31 - April 1, 2016, Tours, France.. In: mAbs, Vol. 8, no. 6, p. 999-1009 (2016). doi:10.1080/19420862.2016.1196521.
Cuvelier, Brieuc ; Eloy, Pierre ; Loira Pastoriza, Cristina ; Ucakar, Bernard ; Sanogo, Abdoul Aziz ; Dupont-Gillain, Christine C. ; Vanbever, Rita. Minimal amounts of dipalmitoylphosphatidylcholine improve aerosol performance of spray-dried temocillin powders for inhalation. In: International Journal of Pharmaceutics, Vol. 495, no. 2, p. 981-990 (2015). doi:10.1016/j.ijpharm.2015.10.019.
Loira Pastoriza, Cristina ; Todoroff, Julie ; Vanbever, Rita. Delivery strategies for sustained drug release in the lungs. In: Advanced Drug Delivery Reviews, Vol. 75, p. 81-94 (2014). doi:10.1016/j.addr.2014.05.017.
Ungaro, Francesca ; Vanbever, Rita. Improving the efficacy of inhaled drugs for severe lung diseases: emerging pulmonary delivery strategies.. In: Advanced Drug Delivery Reviews, Vol. 75, p. 1-2 (2014). doi:10.1016/j.addr.2014.08.001.
Koussoroplis, Salomé Juliette ; Paulissen, Geneviève ; Tyteca, Donatienne ; Goldansaz, Hadi ; Todoroff, Julie ; Barilly, Céline ; Uyttenhove, Catherine ; Van Snick, Jacques ; Cataldo, Didier ; Vanbever, Rita. PEGylation of antibody fragments greatly increases their local residence time following delivery to the respiratory tract.. In: Journal of controlled release : official journal of the Controlled Release Society, Vol. 187, no. C, p. 91-100 (2014). doi:10.1016/j.jconrel.2014.05.021.
Todoroff, Julie ; Lemaire, Muriel ; Fillee, Catherine ; Jurion, Fabienne ; Renauld, Jean-Christophe ; Huygen, Kris ; Vanbever, Rita. Mucosal and systemic immune responses to Mycobacterium tuberculosis antigen 85A following its co-delivery with CpG, MPLA or LTB to the lungs in mice. In: PLoS One, Vol. 8, no. 5, p. e63344 [1-12] (2013). doi:10.1371/journal.pone.0063344.
Koussoroplis, Salomé ; Heywood, Sam ; Uyttenhove, Catherine ; Barilly, Céline ; Van Snick, Jacques ; Vanbever, Rita. Production, purification and biological characterization of mono-PEGylated anti-IL-17A antibody fragments. In: International Journal of Pharmaceutics, Vol. 454, no. 1, p. 107-115 (2013). doi:10.1016/j.ijpharm.2013.06.077.
Todoroff, Julie ; Ucakar, Bernard ; Inglese, Malory ; Vandermarliere, Sophie ; Fillee, Catherine ; Renauld, Jean-Christophe ; Huygen, Kris ; Vanbever, Rita. Targeting the deep lungs, Poloxamer 407 and a CpG oligonucleotide optimize immune responses to Mycobacterium tuberculosis antigen 85A following pulmonary delivery. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 84, no. 1, p. 40-48 (2013). doi:10.1016/j.ejpb.2012.11.020.
Fernandes, Cláudia A ; Fievez, Laurence ; Neyrinck, Audrey M. ; Delzenne, Nathalie M. ; Bureau, Fabrice ; Vanbever, Rita. Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. In: Biochemical and Biophysical Research Communications, Vol. 420, no.4, p. 857-861 (2012). doi:10.1016/j.bbrc.2012.03.088.
Mitragotri, Samir ; Vanbever, Rita. Converting innovative colloids into potent drug delivery carriers: Opportunities and challenges. In: Current Opinion in Colloid & Interface Science, Vol. 16, no. 3, p. 169-170 (2011). doi:10.1016/j.cocis.2011.03.002.
Todoroff, Julie ; Vanbever, Rita. Fate of nanomedicines in the lungs. In: Current Opinion in Colloid & Interface Science, Vol. 16, no. 3, p. 246-254 (June 2011). doi:10.1016/j.cocis.2011.03.001.
Fernandes, Cláudia A. ; Fievez, Laurence ; Ucakar, Bernard ; Neyrinck, Audrey M. ; Fillee, Catherine ; Huaux, François ; Delzenne, Nathalie M. ; Bureau, Fabrice ; Vanbever, Rita. Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice. In: American Journal of Physiology: Lung Cellular and Molecular Physiology, Vol. 300, no. 3, p. L354-L361 (2011). doi:10.1152/ajplung.00198.2010.
Patton, John S ; Brain, Joseph D. ; Davies, Lee A. ; Fiegel, Jennifer ; Gumbleton, Mark ; Kim, Kwang-Jin ; Sakagami, Masahiro ; Vanbever, Rita ; Ehrhardt, Carsten. The particle has landed--characterizing the fate of inhaled pharmaceuticals. In: Journal of Aerosol Medicine and Pulmonary Drug Delivery, Vol. 23, no. Suppl 2, p. S71-87 (2010). doi:10.1089/jamp.2010.0836.
Lubamba, Bob ; Lebacq, Jean ; Lebecque, Patrick ; Vanbever, Rita ; Leonard, Anissa Marie ; Wallemacq, Pierre ; Leal, Teresinha. Airway delivery of low dose miglustat normalizes nasal potential difference in F508del cystic fibrosis mice. In: American Journal of Respiratory and Critical Care Medicine, Vol. 179, no. 11, p. 1022-1028 (2009). doi:10.1164/rccm.200901-0049OC.
Ducreux, Julie ; Crocker, Paul R. ; Vanbever, Rita. Analysis of sialoadhesin expression on mouse alveolar macrophages. In: Immunology Letters, Vol. 124, no. 2, p. 77-80 (2009). doi:10.1016/j.imlet.2009.04.006.
Ducreux, Julie ; Tyteca, Donatienne ; Ucakar, Bernard ; Medts, Thierry ; Crocker, Paul R. ; Courtoy, Pierre J. ; Vanbever, Rita. PEGylation of anti-sialoadhesin monoclonal antibodies enhances their inhibitory potencies without impairing endocytosis in mouse peritoneal macrophages. In: Bioconjugate Chemistry, Vol. 20, no. 2, p. 295-303 (2009). doi:10.1021/bc800390g.
Fernandes, Cláudia A. ; Vanbever, Rita. Preclinical models for pulmonary drug delivery. In: Expert Opinion on Drug Delivery, Vol. 6, no. 11, p. 1231-1245 (2009). doi:10.1517/17425240903241788.
Minne, Antoine ; Boireau, Hélène ; Horta, Maria Joao ; Vanbever, Rita. Optimization of the aerosolization properties of an inhalation dry powder based on selection of excipients. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, no. 3, p. 839-844 (2008). doi:10.1016/j.ejpb.2008.06.013.
Minne, Antoine ; Huaux, François ; Jaworska, Joanna ; Rha, Ro-Dug ; Hamelmann, Eckard ; Vanbever, Rita. Safety evaluation of pulmonary influenza vaccination in healthy and "asthmatic" mice. In: Vaccine, Vol. 26, no. 19, p. 2360-2368 (2008). doi:10.1016/j.vaccine.2008.02.062.
Ducreux, Julie ; Vanbever, Rita ; Crocker, Paul R. The inhibitory potencies of monoclonal antibodies to the macrophage adhesion molecule sialoadhesin are greatly increased following PEGylation. In: Bioconjugate Chemistry, Vol. 19, no. 10, p. 2088-2094 (2008). doi:10.1021/bc800259z.
Ducreux, Julie ; Vanbever, Rita. Crucial Biopharmaceutical Issues Facing Macromolecular Candidates for Inhalation: The Role of Macrophages in Pulmonary Protein Clearance. In: Respiratory Drug Delivery Europe, Vol. 2007, no. on-line publication, p. 31-42 (2007).
Minne, Antoine ; Jaworska, J. ; Gerhold, K. ; Ahrens, B. ; Avagyan, A. ; Vanbever, Rita ; Matricardi, P. M. ; Schmidt, A. C. ; Hamelmann, E.. Intranasal delivery of whole influenza vaccine prevents subsequent allergen-induced sensitization and airway hyper-reactivity in mice. In: Clinical and Experimental Allergy, Vol. 37, no. 8, p. 1250-1258 (2007). doi:10.1111/j.1365-2222.2007.02767.x.
Minne, Antoine ; Louahed, Jamila ; Mehauden, Sybille ; Baras, Benoît ; Renauld, Jean-Christophe ; Vanbever, Rita. The delivery site of a monovalent influenza vaccine within the respiratory tract impacts on the immune response. In: Immunology, Vol. 122, no. 3, p. 316-325 (2007). doi:10.1111/j.1365-2567.2007.02641.x.
Vanbever, Rita. Performance-driven, pulmonary delivery of systemically acting drugs. In: Drug Discovery Today: Technologies, Vol. 2, no. 1, p. 39-46 (2005). doi:10.1016/j.ddtec.2005.05.016.
Reychler, Gregory ; Crémers, Caroline ; Bosquillon, Cynthia ; Vanbever, Rita ; Roeseler, Jean ; Delguste, Pierre ; Liistro, Giuseppe. Étude in vitro de deux modes de nébulisation : ventilation à percussions intrapulmonaires vs. nébulisation pneumatique. In: Kinésithérapie : la revue, Vol. 5, p. 38-41 (2005).
Bosquillon, Cynthia ; Rouxhet, Paul ; Ahimou, François ; Simon, Denis ; Culot, Christine ; Préat, Véronique ; Vanbever, Rita. Aerosolization properties, surface composition and physical state of spray-dried protein powders. In: Journal of Controlled Release, Vol. 99, no. 3, p. 357-367 (2004). doi:10.1016/j.jconrel.2004.07.022.
Lombry, Catherine ; Edwards, David A ; Préat, Véronique ; Vanbever, Rita. Alveolar macrophages are a primary barrier to pulmonary absorption of macromolecules. In: American Journal of Physiology: Lung Cellular and Molecular Physiology, Vol. 286, no. 5, p. L1002-L1OO8 (2004). doi:10.1152/ajplung.00260.2003.
Codrons, Valérie ; Vanderbist, Francis ; Ucakar, Bernard ; Préat, Véronique ; Vanbever, Rita. Impact of formulation and methods of pulmonary delivery on absorption of parathyroid hormone (1-34) from rat lungs. In: Journal of Pharmaceutical Sciences, Vol. 93, no. 5, p. 1241-1252 (2004). doi:10.1002/jps.20053.
Lombry, Catherine ; Marteleur, Aline ; Arras, Mohammed ; Lison, Dominique ; Louahed, Jamila ; Renauld, Jean-Christophe ; Préat, Véronique ; Vanbever, Rita. Local and systemic immune responses to intratracheal instillation of antigen and DNA vaccines in mice. In: Pharmaceutical Research, Vol. 21, no. 1, p. 127-135 (2004). doi:10.1023/B:PHAM.0000012160.00222.55.
Bosquillon, Cynthia ; Préat, Véronique ; Vanbever, Rita. Pulmonary delivery of growth hormone using dry powders and visualization of its local fate in rats. In: Journal of Controlled Release, Vol. 96, no. 2, p. 233-244 (2004). doi:10.1016/j.jconrel.2004.01.027.
Denet, Anne-Rose ; Vanbever, Rita ; Préat, Véronique. Skin electroporation for transdermal and topical delivery. In: Advanced Drug Delivery Reviews, Vol. 56, no. 5, p. 659-674 (2004). doi:10.1016/j.addr.2003.10.027.
Codrons, Valérie ; Vanderbist, Francis ; Verbeeck, Roger-K. ; Arras, Mohammed ; Lison, Dominique ; Préat, Véronique ; Vanbever, Rita. Systemic delivery of parathyroid hormone (1-34) using inhalation dry powders in rats. In: Journal of Pharmaceutical Sciences, Vol. 92, no. 5, p. 938-950 (2003). doi:10.1002/jps.10346.
Lombry, Catherine ; Bosquillon, Cynthia ; Préat, Véronique ; Vanbever, Rita. Confocal imaging of rat lungs following intratracheal delivery of dry powders or solutions of fluorescent probes. In: Journal of Controlled Release, Vol. 83, no. 3, p. 331-341 (2002). doi:10.1016/S0168-3659(02)00174-8.
Bosquillon, Cynthia ; Lombry, Catherine ; Préat, Véronique ; Vanbever, Rita. Comparison of particle sizing techniques in the case of inhalation dry powders. In: Journal of Pharmaceutical Sciences, Vol. 90, no. 12, p. 2032-2041 (2001). doi:10.1002/jps.1154.
Bosquillon, Cynthia ; Lombry, Catherine ; Préat, Véronique ; Vanbever, Rita. Influence of formulation excipients and physical characteristics of inhalation dry powders on their aerosolization performance. In: Journal of Controlled Release, Vol. 70, no. 3, p. 329-339 (2001). doi:10.1016/S0168-3659(00)00362-X.
Vanbever, Rita. Administration transdermique de médicaments par electroporation. In: Bulletin et mémoires de l'Académie royale de médecine de Belgique, Vol. 154, no. 6 Pt 2, p. 327-333 (1999).
Vanbever, Rita ; Pliquett, Uwe F. ; Préat, Véronique ; Weaver, James C.. Comparison of the effects of short, high-voltage and long, medium-voltage pulses on skin electrical and transport properties. In: Journal of Controlled Release, Vol. 60, no. 1, p. 35-47 (1999). doi:10.1016/S0168-3659(99)00018-8.
Zewert, Thomas E. ; Pliquett, Uwe F. ; Vanbever, Rita ; Langer, Robert ; Weaver, James C.. Creation of transdermal pathways for macromolecule transport by skin electroporation and a low toxicity, pathway-enlarging molecule. In: Bioelectrochemistry and Bioenergetics, Vol. 49, no. 1, p. 11-20 (1999). doi:10.1016/S0302-4598(99)00056-2.
Vanbever, Rita ; Mintzes, Jeffrey D. ; Wang, Jue ; Nice, Jacquelyn ; Chen, Donghao ; Batycky, Richard ; Langer, Robert ; Edwards, David A.. Formulation and physical characterization of large porous particles for inhalation. In: Pharmaceutical Research, Vol. 16, no. 11, p. 1735-1742 (1999). doi:10.1023/A:1018910200420.
Vanbever, Rita ; Préat, Véronique. In vivo efficacy and safety of skin electroporation. In: Advanced Drug Delivery Reviews, Vol. 35, no. 1, p. 77-88 (1999). doi:10.1016/S0169-409X(98)00064-7.
Ben-Jebria, Abdellaziz ; Chen, Donghao ; Eskew, Mary Lou ; Vanbever, Rita ; Langer, Robert ; Edwards, David A.. Large porous particles for sustained protection from carbachol-induced bronchoconstriction in guinea pigs.. In: Pharmaceutical Research, Vol. 16, no. 4, p. 555-561 (1999). doi:10.1023/A:1018879331061.
Vanbever, Rita ; Ben-Jebria, Abdellaziz ; Mintzes, Jeffrey D. ; Langer, Robert ; Edwards, David A.. Substained release of insulin from insoluble inhaled particles. In: Drug Development Research, Vol. 48, no. 4, p. 178-185 (1999). doi:10.1002/(SICI)1098-2299(199912)48:4<178::AID-DDR5>3.0.CO;2-I.
Vanbever, Rita ; Fouchard, Delphine ; Jadoul, Anne ; De Morre, Nathalie ; Préat, Véronique ; Marty, Jean-Paul. In vivo noninvasive evaluation of hairless rat skin after high-voltage pulse exposure. In: Skin Pharmacology and Applied Skin Physiology, Vol. 11, no. 1, p. 23-34 (1998). doi:10.1159/000029805.
Pliquett, Uwe F. ; Vanbever, Rita ; Préat, Véronique ; Weaver, James C.. Local transport regions (LTRs) in human stratum corneum due to long and short 'high voltage' pulses. In: Bioelectrochemistry and Bioenergetics, Vol. 47, no. 1, p. 151-161 (1998). doi:10.1016/S0302-4598(98)00180-9.
Vanbever, Rita ; Langers, Gilles ; Montmayeur, Sonia ; Préat, Véronique. Transdermal delivery of fentanyl: rapid onset of analgesia using skin electroporation. In: Journal of Controlled Release, Vol. 50, no. 1-3, p. 225-235 (1998). doi:10.1016/S0168-3659(97)00147-8.
Vanbever, Rita ; Leroy, Marie-Ange ; Préat, Véronique. Transdermal permeation of neutral molecules by skin electroporation. In: Journal of Controlled Release, Vol. 54, no. 3, p. 243-250 (1998). doi:10.1016/S0168-3659(97)00146-6.
Weaver, James C. ; Vanbever, Rita ; Vaughan, Timothy E. ; Prausnitz, Mark R.. Heparin alters transdermal transport associated with electroporation. In: Biochemical and Biophysical Research Communications, Vol. 234, no. 3, p. 637-640 (1997). doi:10.1006/bbrc.1997.6701.
Vanbever, Rita ; Prausnitz, Mark R. ; Préat, Véronique. Macromolecules as novel transdermal transport enhancers for skin electroporation. In: Pharmaceutical Research, Vol. 14, no. 5, p. 638-644 (1997). doi:10.1023/A:1012161313701.
Vanbever, Rita ; Le Boulengé, Éric ; Préat, Véronique. Transdermal delivery of fentanyl by electroporation. 1 : influence of electrical factors. In: Pharmaceutical Research, Vol. 13, no. 4, p. 559-565 (1996). doi:10.1023/A:1016093920875.
Vanbever, Rita ; De Morre, Nathalie ; Préat, Véronique. Transdermal delivery of fentanyl by electroporation. 2 : mechanisms involved in drug transport. In: Pharmaceutical Research, Vol. 13, no. 9, p. 1360-1366 (1996). doi:10.1023/A:1016073917125.
Vanbever, Rita ; Préat, Véronique. Factors affecting transdermal delivery of metoprolol by electroporation. In: Bioelectrochemistry and Bioenergetics, Vol. 38, no. 1, p. 223-228 (1995). doi:10.1016/0302-4598(95)01830-8.
Vanbever, Rita ; Lecouturier, Nathalie ; Préat, Véronique. Transdermal delivery of metoprolol by electroporation. In: Pharmaceutical Research, Vol. 11, no. 11, p. 1657-1662 (1994). doi:10.1023/A:1018930425591.
Koussoroplis, Salomé-Juliette ; Vanbever, Rita. Peptides and Proteins: Pulmonary Absorption. In: James Swarbrick, Encyclopedia of Pharmaceutical Science and Technology, Fourth Edition, Taylor & Francis: (United Kingdom) Oxford, 2013, [1-11]. 978-1-8418-4819-8. doi:10.1081/E-EPT4-120050324.
Vanbever, Rita. Optimization of dry powder aerosols for systemic drug delivery. In: Jan C.M. Marijnissen, Leon Gradon, Optimization of Aerosol Drug Delivery, Kluwer Academic Publishers: (The Netherlands) Dordrecht, 2003, p. 91-103. 1-4020-1651-4.
Préat, Véronique ; Vanbever, Rita. Skin electroporation for transdermal and topical drug delivery. In: Richard H. Guy and Jonathan Hadgraft, Transdermal Drug Delivery Systems : Revised And Expanded, 2nd Edition, Informa Healthcare: (United States) Boca Raton, FL, 2002, p. 227-254. 978-0-8247-0861-0. doi:10.1201/9780203909683.ch6.
Préat, Véronique ; Vanbever, Rita. Topical delivery by iontophoresis. In: Marc Paye, Andre O. Barel, Howard I. Maibach, Handbook of Cosmetic Science and Technology, 2nd Edition, Taylor & Francis Group: (United States) Boca Raton, FL, 2001, p. 211-219. 978-1-57444-824-5.
Prausnitz, Mark R. ; Pliquett, Uwe ; Vanbever, Rita. Mechanistic studies of skin electroporation using biophysical methods. In: Mark J. Jaroszeski, Richard Heller, Richard Gilbert, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery : Electrically Mediated Delivery of Molecules to Cells (Methods in Molecular Medicine; 37), Humana Press: (United States) Totowa, N.J., 2000, p. 213-245. 978-0-89603-606-2. doi:10.1385/1-59259-080-2:213.
Vanbever, Rita ; Préat, Véronique. Transdermal drug delivery by skin electroporation in the rat. In: Mark J. Jaroszeski, Richard Heller, Richard Gilbert, Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery : Electrically Mediated Delivery of Molecules to Cells (Methods in Molecular Medicine; 37), Humana Press: (United States) Totowa, N.J., 2000, p. 457-471. 978-0-89603-606-2. doi:10.1385/1-59259-080-2:457.
Dugernier, Jonathan ; Reychler, Gregory ; Wittebole, Xavier ; Roeseler, Jean ; Sottiaux , Thierry ; Michotte, Jean-Bernard ; Vanbever, Rita ; Dugernier , Thierry ; Goffette, Pierre ; Docquier, Marie-Agnès ; Raftopoulos, Christian ; Hantson, Philippe ; Jamar, François ; Laterre, Pierre-François. Lung deposition of a radiolabeled aerosol with two ventilation modalities during invasive mechanical ventilation: a randomized comparative study. 28th Annual Congress of the Society of Intensive Care Medicine (ESICM) ((Germany) Berlin, du 03/10/2015 au 07/10/2015). In: Intensive Care Medicine Experimental, Vol. 3, no.Suppl. 1 , p. A10 (2015). doi:10.1186/2197-425X-3-S1-A10.
Ducreux, Julie ; Vanbever, Rita. Effect of macrophage PEGylation on endocytosis modes. Annual Meeting & Exposition of the Controlled Release Society (New-York, du 12/07/2008 au 16/07/2008).
Ducreux, Julie ; Vanbever, Rita. Expression of sialoadhesin on alveolar macrophages, a macrophage-restricted receptor. International Society for Aerosols in Medicine (Tours, du 16/06/2007 au 20/06/2007).
Ducreux, Julie ; Vanbever, Rita. Assessment of alveolar macrophages role in growth hormone pulmonary fate. Annual Meeting & Exposition of the Controlled Release Society (Vienne, du 22/07/2006 au 26/07/2006).
DUMOULIN Mireille ; MORALES YÀNEZ Francisco ; Redeghieri, Paola ; Vanbever, Rita ; Vanderstraeten, Jessica ; Leal, Teresinha ; Mottais, Angélique ; MUYLDERMANS Serge ; VINCKE Cécile. Single-domain antibody for inhibition of neutrophil elastase activity. Déposé (30/06/2023). Belgium.
Vanbever, Rita ; Koussoroplis, Salomé ; Cataldo, Didier ; Van Snick, Jacques. Method for increasing the bioavailability of inhaled compounds - US 2019/016177 A1. .
Vanbever, Rita ; Koussoroplis, Salomé ; Van Snick, Jacques ; Cataldo, Didier. Method for increasing the bioavailability of inhaled compounds. Numéro de priorité ; Déposé (16/01/2015) ; Publié (23/07/2015). AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VE, VN, ZA, ZM ,ZW, ARIPO, EURASIAN, EUROPEAN, OAPI.
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Particles for Inhalation Having Sustained Release Properties. Numéro de priorité ; Déposé (29/08/2011) ; Publié (03/05/2012). (United States) Cambridge, MA.
Vanbever, Rita ; Langer, Robert S. ; Edwards , David A. ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao. Particles for inhalation having sustained release properties . Numéro de priorité ; Déposé (07/03/2002) ; Publié (30/05/2006). (United Staes) Cambridge, MA.
Vanbever, Rita ; Edwards, David. Chemical and physical modulators of bioavailability of inhaled compositions. Numéro de priorité ; Numéro de priorité ; Numéro de priorité (2005-01-13). .
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao. Particles for inhalation having sustained release properties . Numéro de priorité ; Déposé (29/12/2000) ; Publié (02/05/2005). (United States) Cambridge, MA.
Chen, Donghao ; Edwards, David A. ; Evora, Carmen ; Hanes, Justin ; Langer, Robert S. ; Mintzes, Jeffrey ; Vanbever, Rita ; Wang, Jue . Preparation de particules pour inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (30/06/2005). (United States) Cambridge, MA.
Chen, Donghao ; Edwards, David A. ; Evora, Carmen ; Hanes, Justin ; Langer, Robert S. ; Mintzes, Jeffrey ; Vanbever, Rita ; Wang, Jue . Preparation of particles for inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (19/01/2005). (United Staes) Cambridge, MA.
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Preparation of novel particles for inhalation. Numéro de priorité ; Déposé (13/09/1999) ; Publié (25/11/2003). (United States) Cambridge, MA.
Weaver, James C. ; Pliquett, Uwe ; Vanbever, Rita ; Gowrishankar, Thiruvallur R. ; Zewert, Thomas E. Biopotential measurement including electroporation of tissue surface. Numéro de priorité ; Déposé (22/05/1998) ; Publié (04/07/2000). (United Staes) Cambridge, MA.
Edwards, David A. ; Langer, Robert S. ; Vanbever, Rita ; Mintzes, Jeffrey ; Wang, Jue ; Chen, Donghao . Preparation of particles for inhalation. Numéro de priorité ; Déposé (17/11/1997) ; Publié (16/11/1999). (United States) Cambridge, MA.
Weaver, James C. ; Chen, Tani ; Cullander, Christopher ; Guy, Richard ; Langer, Robert S. ; Zewert, Thomas E. ; Pliquett , Uwe ; Vanbever, Rita ; Prausnitz, Mark R.. Introduction of modifying agents into skin by electroporation. Numéro de priorité ; Déposé (15/06/1999) ; Publié (/). (United Staes) Cambridge, MA.