2026
Randy Buzisa Mbuku
Therapeutic innovation in Prosthetic Joint Infections: A biofilm-disrupting and drug-delivering hydrogel incorporating an enzymatic cocktail
Directors: Olivier Cornu, Françoise Van Bambeke
2025
Gwenaëlle Mahieu
An integrated pharmacokinetic, pharmacogenomic and pharmacodynamic study of fluoroquinolones in the context of intracellular infections
Directors: Françoise Van Bambeke
2024
Audrey Comein
Intracellular persistence of Pseudomonas aeruginosa : when bacteria play hide-and-seek with antibiotics
Director: Françoise Van Bambeke
Steven De Soir
Exploring Phage-Antibiotic Synergies for the Treatment of Biofilm-related Infectious Diseases
Directors: Françoise Van Bambeke, Jean-Paul Pirnay
Zhifen Wang
Evaluation of the activity of antibiotics and adjuvant strategies against dual species biofilms in the context of cystic fibrosis
Director: Françoise Van Bambeke
2023
Mandeep Kaur
VacJ : a regulatory hub for Pseudomonas aeruginosa outer membrane asymmetry, modulates virulence factors, lipid composition, mechanical, biophysical and functional properties of the cell envelope
Directors: Marie-Paule Mingeot-Leclercq, Joseph Lorent
Hélène Thirot
Overview of Linezolid use in Belgium : towards a better appraisal of the risk of adverse drug reactions
Directors: Françoise Van Bambeke, Anne Spinewine
2022
Perrin Ngougni Pokem
Clinical pharmacokinetics of temocillin: A way to optimize personalized dosing
Directors: Françoise Van Bambeke, Laure Elens, Arnaud Carpon
Gang Wang
Reviving disused antibiotics against Gram-negative ESKAPE pathogens: combination with the polyaminoisoprenyl potentiator NV716
Director: Françoise Van Bambeke
2021
Hervé Poilvache
In-vitro and in-vivo study of biofilm disruption strategies for the treatment of Prosthetic Joint Infections
Director: Olivier Cornu, co-director: Françoise Van Bambeke
Frédéric Peyrusson
Intracellular persistence of Staphylococcus aureus: from observations to mechanisms
Director: Françoise Van Bambeke
Albert Ruiz Sorribas
Targeting inter-kingdom biofilms with antimicrobials and hydrolytic enzymes
Director: Françoise Van Bambeke
2020
Alice Ameryckx
Design, synthesis and evaluation of D-alanyl-D-alanine ligase inhibitors : an attractive target for the development of antimicrobial agents
Directors: Raphaël Frédérick, Françoise Van Bambeke
Jules César Bayiha
Characterization of the effects of the budesonide-hydroxypropyl-ß-cyclodextrin complex on lipid membranes and the cellular response to hydrogen peroxide and lipopolysaccharide
Director: Marie-Paule Mingeot-Leclercq
Yvan Diaz Iglesias
Activity of antibiotics against in vitro mono-species biofilms of P. aeruginosa and S. aureus in the context of cystic fibrosis: The influence of the culture medium
Director: Françoise Van Bambeke
Tiep Khac Nguyen
Antibiotic resistance in Vietnam in relation with persistent forms of infection
Director: Françoise Van Bambeke
2019
Ana Miranda Bastos
Towards optimization of temocillin exposure in haemodialysis patients: a translational approach from bedside-to-bench-to-bedside
Directors: Françoise Van Bambeke, Anne Spinewine
Thanh Binh Le
Anti-parasitic activity of Vietnamese essential oils and study of the mode of action of eugenol, one of their active constituents
Directors: Joëlle Leclercq, Marie-Paule Mingeot-Leclercq
Tamara Milosevic
Mitochondrial toxicity induced by oxazolidinone antibiotics: insights from studies in human cell lines and primary cells
Director: Françoise Van Bambeke
Sandrine Verstraeten
Contribution of membrane lipids to the activity of the saponin ginsenoside Rh2
Directors: Marie-Paule Mingeot-Leclercq, Donatienne Tyteca
2017
Ahalieyah Anantharajah
Contribution to the understanding of Pseudomonas aeruginosa virulence in search of innovative therapeutic approaches: focus on type III secretion system
Directors: Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq
Catherine Leonard
Contribution of plasma membrane lipid domains to red blood cell (re)shaping
Directors: Tyteca Donatienne, Marie-Paule Mingeot-Leclercq
Muhammad Hariri Mustafa
Development of new antibiotic combinations to be administered by dry powder for inhalation to patients with Cystic Fibrosis: microbiological, pharmacological and pharmaceutical studies
Director: Francis Vanderbist, Françoise Van Bambeke
2016
Hussein Chalhoub
Impact of efflux mechanisms on susceptibility and resistance to beta-lactam antibiotics in Pseudomonas aeruginosa: beyond the usual concepts
Director: Françoise Van Bambeke
2014
Nathalie Vandevelde
Streptococcus pneumoniae infections in a context of Chronic Obstructive Pulmonary Disease (COPD). Study of the factors contributing to the recurrence of the disease
Director: Françoise Van Bambeke
2013
Ann Lismond
Antimicrobial resistance in Streptococcus pneumoniae isolates from community acquired pneumonia in Belgium, with special reference to efflux mechanism
Directors: Paul Tulkens, Françoise Van Bambeke
Els Ampe
Continuous Infusion of Vancomycin in non-ICU Patients: Why, How and What's the Benefit ?
Director: Paul Tulkens
Sophie Denamur
Intracellular mechanisms of apoptosis induced by aminoglycoside antibiotics
Directors: Marie-Paule Mingeot-Leclercq, Paul Tulkens
Joseph Lorent
Membrane interactions of lipopeptides and saponins, two groups of natural amphiphiles
Directors: Marie-Paule Mingeot-Leclercq, Joëlle Leclercq
2012
Laetitia Garcia
Intracellular pharmacodynamics of antibiotics Against small-colony variants of Staphylococcus aureus In in vitro models of professional phagocytic cells
Director: Françoise Van Bambeke
Coralie Vallet
Characterization of the active efflux of fluoroquinolones in eukaryotic cells
Director: Françoise Van Bambeke
2011
Hayet Bensikaddour
Interactions between fluroquinolones and lipids: biophysical studies
Director: Marie-Paule Mingeot-Leclercq
2010
Pierre Baudoux
Antibiotic activity against intracellular Staphylococcus aureus
Directors: Paul Tulkens, Françoise Van Bambeke
Sébastien Van de Velde
Intracellular localization of Listeria monocytogenes: impact on its proteome and antibiotic treatments
Director: Paul Tulkens
