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Avenue Hippocrate 75/B1.75.02
1200 Woluwe-Saint-Lambert
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- Didier Vertommen
Didier Vertommen
Logisticien de recherche en chef
2023
Cloos, Anne-Sophie ; Pollet, Hélène ; Stommen, Amaury ; Maja, Mauriane ; Lingurski, Maxime ; Brichard, Bénédicte ; Lambert, Catherine ; Henriet, Patrick ; Pierreux, Christophe ; Pyr dit Ruys, Sébastien ; Van Der Smissen, Patrick ; Vikkula, Miikka ; Gatto, Laurent ; Martin, Manon ; Brouillard, Pascal ; Vertommen, Didier ; Tyteca, Donatienne. Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance but not maturation defects. In: Blood advances, (2023). doi:10.1182/bloodadvances.2022009114 (Accepté/Sous presse).
2022
Sorgeloos, Frédéric ; Peeters, Michael ; Hayashi, Yohei ; Borghese, Fabian ; Capelli, Nicolas ; Drappier, Melissa ; Cesaro, Teresa ; Colau, Didier ; Stroobant, Vincent ; Vertommen, Didier ; de Bodt, Grégory ; Messe, Stéphane ; Forné, Ignasi ; Mueller-Planitz, Felix ; Collet, Jean-François ; Michiels, Thomas. A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif.. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, no.5, p. e2114647119 (2022). doi:10.1073/pnas.2114647119.
2022
Lizcano-Perret, Belén ; Lardinois, Cécile ; Wavreil, Fanny ; Hauchamps, Philippe ; Herinckx, Gaëtan ; Sorgeloos, Frédéric ; Vertommen, Didier ; Gatto, Laurent ; Michiels, Thomas ; Belov, George A.. Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic. In: PLOS Pathogens, Vol. 18, no. 12, p. e1011042 (2022). doi:10.1371/journal.ppat.1011042.
2022
Ward, Bradley ; Yombi, Jean Cyr ; Balligand, Jean-Luc ; Cani, Patrice D. ; Collet, Jean-François ; De Greef, Julien ; Dewulf, Joseph P. ; Gatto, Laurent ; Haufroid, Vincent ; Jodogne, Sébastien ; Kabamba-Mukadi, Benoît ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Elens, Laure ; Belkhir, Leïla. HYGIEIA: HYpothesizing the Genesis of Infectious Diseases and Epidemics through an Integrated Systems Biology Approach. In: Viruses, Vol. 14, no. 7, p. 1373 [1-17] (2022). doi:10.3390/v14071373.
2022
Kostyuk, Alexander I ; Tossounian, Maria-Armineh ; Panova, Anastasiya S ; Thauvin, Marion ; Raevskii, Roman I ; Ezeriņa, Daria ; Wahni, Khadija ; Van Molle, Inge ; Sergeeva, Anastasia D ; Vertommen, Didier ; Gorokhovatsky, Andrey Yu ; Baranov, Mikhail S ; Vriz, Sophie ; Messens, Joris ; Bilan, Dmitry S ; Belousov, Vsevolod V. Hypocrates is a genetically encoded fluorescent biosensor for (pseudo)hypohalous acids and their derivatives.. In: Nature communications, Vol. 13, no.1, p. 171 (2022). doi:10.1038/s41467-021-27796-2 (Soumis).
2022
Johanns, Manuel ; Corbet, Cyril ; Jacobs, Roxane ; Drappier, Melissa ; Bommer, Guido ; Herinckx, Gaëtan ; Vertommen, Didier ; Tajeddine, Nicolas ; Young, David ; Messens, Joris ; Feron, Olivier ; Steinberg, Gregory R ; Hue Louis ; Rider, Mark H.. Inhibition of basal and glucagon-induced hepatic glucose production by 991 and other pharmacological AMPK activators.. In: The Biochemical journal, Vol. 479, no.12, p. 1317-1336 (2022). doi:10.1042/BCJ20220170.
2022
Rademaker, Gilles ; Costanza, Brunella ; Pyr dit Ruys, Sébastien ; Peiffer, Raphaël ; Agirman, Ferman ; Maloujahmoum, Naïma ; Vertommen, Didier ; Turtoi, Andrei ; Bellahcène, Akeila ; Castronovo, Vincent ; Peulen, Olivier. Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination. In: Oncogenesis, Vol. 11, no.1, p. 11-42 (2022). doi:10.1038/s41389-022-00416-4 (Soumis).
2022
Heremans, Isaac ; Caligiore, Francesco ; Gerin, Isabelle ; Bury, Marina ; Lutz, Marilena ; Graff, Julie ; Stroobant, Vincent ; Vertommen, Didier ; Teleman, Aurelio A ; Van Schaftingen, Emile ; Bommer, Guido. Parkinson's disease protein PARK7 prevents metabolite and protein damage caused by a glycolytic metabolite.. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, no.4, p. e2111338119 (2022). doi:10.1073/pnas.2111338119.
2022
Vergnes, Alexandra ; Henry, Camille ; Grassini, Gaia ; Loiseau, Laurent ; El Hajj, Sara ; Denis, Yann ; Galinier, Anne ; Vertommen, Didier ; Aussel, Laurent ; Ezraty, Benjamin ; Crosson, Sean. Periplasmic oxidized-protein repair during copper stress in E. coli: A focus on the metallochaperone CusF. In: PLOS Genetics, Vol. 18, no.7, p. e1010180 (2022). doi:10.1371/journal.pgen.1010180 (Soumis).
2022
Ouni, Emna ; Nedbal, Valerie ; Da Pian, Marta ; Cao, Hangbao ; Haas, Kalina T ; Peaucelle, Alexis ; Van Kerk, Olivier ; Herinckx, Gaëtan ; Marbaix, Etienne ; Dolmans, Marie-Madeleine ; Tuuri, Timo ; Otala, Marjut ; Andrade Amorim, Christiani ; Vertommen, Didier. Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.. In: Matrix biology : journal of the International Society for Matrix Biology, Vol. 109, no.-, p. 91-120 (2022). doi:10.1016/j.matbio.2022.03.005.
2022
Ouni, Emna ; Nedbal, Valerie ; Da Pian, Marta ; Cao, Hangbao ; Haas, Kalina T ; Peaucelle, Alexis ; Van Kerk, Olivier ; Herinckx, Gaetan ; Marbaix, Etienne ; Dolmans, Marie-Madeleine ; Tuuri, Timo ; Otala, Marjut ; Amorim, Christiani A ; Vertommen, Didier. Proteome-wide and matrisome-specific atlas of the human ovary computes fertility biomarker candidates and open the way for precision oncofertility.. In: Matrix biology : journal of the International Society for Matrix Biology, Vol. 109, p. 91-120 (2022). doi:10.1016/j.matbio.2022.03.005.
2022
Pecquet, Christian ; Papadopoulos, Nicolas ; Balligand, Thomas ; Chachoua, Ilyas ; Tisserand, Amandine ; Vertenoeil, Gaëlle ; Nedelec, Audrey ; Vertommen, Didier ; Roy, Anita ; Marty, Caroline ; Nivarthi, Harini ; Defour, Jean-Philippe ; El-Khoury, Mira ; Hug, Eva ; Xu, Erica ; Zagrijtschuk, Oleh ; Fertig, Emmanuel ; Marta, Daciana ; Gisslinger, Heinz ; Gisslinger, Bettina ; Schalling, Martin ; Casetti, Ilaria ; Rumi, Elisa ; Pietra, Daniela ; Cavalloni, Chiara ; Arcaini, Luca ; Cazzola, Mario ; Komatsu, Norio ; Kihara, Yoshihiko ; Sunami, Yoshitaka ; Edahiro, Yoko ; Araki, Marito ; Lesyk, Roman ; Buxhofer-Ausch, Veronika ; Heibl, Sonja ; Pasquier, Florence ; Havelange, Violaine ; Plo, Isabelle ; Vainchenker, William ; Kralovics, Robert ; Constantinescu, Stefan N.. Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms. In: Secreted Mutant Calreticulins As Rogue Cytokines in Myeloproliferative Neoplasms, Vol. ., no.., p. . (2022) (Accepté/Sous presse).
2022
Hakanen, Janne ; Parmentier, Nicolas ; Sommacal, Leonie ; Garcia-Sanchez, Dario ; Aittaleb, Mohamed ; Vertommen, Didier ; Zhou, Libing ; Ruiz-Reig, Nuria ; Tissir, Fadel. The Celsr3-Kif2a axis directs neuronal migration in the postnatal brain. In: Progress in Neurobiology, Vol. 208, no.1, p. 102177 (2022). doi:10.1016/j.pneurobio.2021.102177.
2022
Dontaine, Justine ; Bouali, Asma ; Daussin, Frederic ; Bultot, Laurent ; Vertommen, Didier ; Martin, Manon ; Rathagirishnan, Raahulan ; Cuillerier, Alexanne ; Horman, Sandrine ; Beauloye, Christophe ; Gatto, Laurent ; Lauzier, Benjamin ; Bertrand, Luc ; Burelle, Yan. The intra-mitochondrial O-GlcNAcylation system rapidly modulates OXPHOS function and ROS release in the heart.. In: Communications biology, Vol. 5, no.1, p. 349 (2022). doi:10.1038/s42003-022-03282-3.
2021
Kerselidou, Despoina ; Dohai, Bushra Saeed ; Nelson, David R. ; Daakour, Sarah ; De Cock, Nicolas ; Hassoun, Zahra Al Oula ; Kim, Dae-Kyum ; Olivet, Julien ; El Assal, Diana C. ; Jaiswal, Ashish ; Alzahmi, Amnah ; Saha, Deeya ; Pain, Charlotte ; Matthijssens, Filip ; Lemaitre, Pierre ; Herfs, Michael ; Chapuis, Julien ; Ghesquiere, Bart ; Vertommen, Didier ; Kriechbaumer, Verena ; Knoops, Kèvin ; Lopez-Iglesias, Carmen ; van Zandvoort, Marc ; Lambert, Jean-Charles ; Hanson, Julien ; Desmet, Christophe ; Thiry, Marc ; Lauersen, Kyle J. ; Vidal, Marc ; Van Vlierberghe, Pieter ; Dequiedt, Franck ; Salehi-Ashtiani, Kourosh ; Twizere, Jean-Claude. Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells. In: Science Advances, Vol. 7, no.19, p. eabe8349 (2021). doi:10.1126/sciadv.abe8349.
2021
Denis, Manon ; Dupas, Thomas ; Persello, Antoine ; Dontaine, Justine ; Bultot, Laurent ; Betus, Charlotte ; Pelé, Thomas ; Dhot, Justine ; Erraud, Angélique ; Maillard, Anaïs ; Montnach, Jérôme ; Leroux, Aurélia A. ; Bigot-Corbel, Edith ; Vertommen, Didier ; Rivière, Matthieu ; Lebreton, Jacques ; Tessier, Arnaud ; Waard, Michel De ; Bertrand, Luc ; Rozec, Bertrand ; Lauzier, Benjamin. An O-GlcNAcylomic Approach Reveals ACLY as a Potential Target in Sepsis in the Young Rat. In: International Journal of Molecular Sciences, Vol. 22, no.17, p. 9236 (2021). doi:10.3390/ijms22179236.
2021
Okella, Hedmon ; Ikiriza, Hilda ; Ochwo, Sylvester ; Ajayi, Clement Olusoji ; Ndekezi, Christian ; Nkamwesiga, Joseph ; Kaggwa, Bruhan ; Aber, Jacqueline ; Mtewa, Andrew Glory ; Koffi, Tindo Kevin ; Odongo, Steven ; Vertommen, Didier ; Kato, Charles Drago ; Ogwang, Patrick Engeu. Identification of Antimicrobial Peptides Isolated From the Skin Mucus of African Catfish, (Burchell, 1822).. In: Frontiers in microbiology, Vol. 12, no.1, p. 794631 (2021). doi:10.3389/fmicb.2021.794631.
2021
Muffels, Irena J J ; Wiame, Elsa ; Fuchs, Sabine A ; Massink, Maarten P G ; Rehmann, Holger ; Musch, Jiska L I ; Van Haaften, Gijs ; Vertommen, Didier ; Van Schaftingen, Emile ; van Hasselt, Peter M. NAA80 bi-allelic missense variants result in high-frequency hearing loss, muscle weakness and developmental delay.. In: Brain communications, Vol. 3, no.4, p. fcab256 (2021). doi:10.1093/braincomms/fcab256.
2021
Cesaro, Teresa ; Hayashi, Yohei ; Borghese, Fabian ; Vertommen, Didier ; Wavreil, Fanny ; Michiels, Thomas. PKR activity modulation by phosphomimetic mutations of serine residues located three aminoacids upstream of double-stranded RNA binding motifs. In: Scientific Reports, Vol. 11, no.1, p. 2045-2322 (2021). doi:10.1038/s41598-021-88610-z.
2021
van Caloen, Gabrielle ; Schmitz, Sandra ; van Marcke, Cédric ; Caignet, Xavier ; Mendola, Antonella ; Pyr Dit Ruys, Sébastien ; Roger, Pierre P ; Vertommen, Didier ; Machiels, Jean-Pascal. Preclinical Evaluation of the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor, Ribociclib, and Cetuximab in Squamous Cell Carcinoma of the Head and Neck.. In: Cancers, Vol. 13, no.6, p. 1251 (2021). doi:10.3390/cancers13061251.
2021
Dupas, Thomas ; Denis, Manon ; Dontaine, Justine ; Persello, Antoine ; Bultot, Laurent ; Erraud, Angélique ; Vertommen, Didier ; Bouchard, Bertrand ; Tessier, Arnaud ; Rivière, Matthieu ; Lebreton, Jacques ; Bigot-Corbel, Edith ; Montnach, Jérôme ; De Waard, Michel ; Gauthier, Chantal ; Burelle, Yan ; Olson, Aaron K ; Rozec, Bertrand ; Des Rosiers, Christine ; Bertrand, Luc ; Issad, Tarik ; Lauzier, Benjamin. Protein O-GlcNAcylation levels are regulated independently of dietary intake in a tissue and time-specific manner during rat postnatal development.. In: Acta physiologica (Oxford, England), Vol. 231, no. 3, p. e13566 (2021). doi:10.1111/apha.13566 (Accepté/Sous presse).
2021
Henry, Camille ; Loiseau, Laurent ; Vergnes, Alexandra ; Vertommen, Didier ; Mérida-Floriano, Angela ; Chitteni-Pattu, Sindhu ; Wood, Elizabeth A ; Casadesús, Josep ; Cox, Michael M ; Barras, Frédéric ; Ezraty, Benjamin. Redox controls RecA protein activity via reversible oxidation of its methionine residues. In: eLife, Vol. 10 (2021). doi:10.7554/elife.63747 (Accepté/Sous presse).
2021
He, Huaming ; Denecker, Jordi ; Van Der Kelen, Katrien ; Willems, Patrick ; Pottie, Robin ; Phua, Su Yin ; Hannah, Matthew A ; Vertommen, Didier ; Van Breusegem, Frank ; Mhamdi, Amna. The Arabidopsis Mediator Complex Subunit 8 Regulates Oxidative Stress Responses. In: The Plant Cell, (2021). doi:10.1093/plcell/koab079 (Accepté/Sous presse).
2021
Luo, Ting ; Pueyo, Julia Malo ; Wahni, Khadija ; Yvanoff, Charlotte ; Lazar, Tamas ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Ezeriņa, Daria ; Messens, Joris. Thiol-disulphide independent in-cell trapping for the identification of peroxiredoxin 2 interactors. In: Redox Biology, Vol. 46, no.1, p. 102066 (2021). doi:10.1016/j.redox.2021.102066.
2021
Spillier, Quentin ; Ravez, Séverine ; Dochain Simon ; Vertommen, Didier ; Thabault, Léopold ; Feron, Olivier ; Frédérick, Raphaël. Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments. In: Molecules, Vol. 26, no. 2, p. 477 (2021). doi:10.3390/molecules26020477.
2020
Pollet, Hélène ; Cloos, Anne-Sophie (co-first author) ; Stommen, Amaury ; Vanderroost, Juliette ; Conrard, Louise ; Paquot, Adrien ; Ghodsi, Marine ; Carquin, Mélanie ; Léonard, Anne-Catherine ; Guthmann, Manuel ; Lingurski, Maxime ; Vermylen, Christiane ; Killian, Theodore ; Gatto, Laurent ; Rider, Mark H. ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Vikkula, Miikka ; Brouillard, Pascal ; Van Der Smissen, Patrick ; Muccioli, Giulio ; Tyteca, Donatienne. Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis. In: Biomolecules, Vol. 10, no. 8, p. 1120 [1-25] (2020). doi:10.3390/biom10081120.
2020
Li, Zeng ; Pinto Torres, Joar Esteban ; Goossens, Julie ; Vertommen, Didier ; Caljon, Guy ; Sterckx, Yann G.-J. ; Magez, Stefan. An Unbiased Immunization Strategy Results in the Identification of Enolase as a Potential Marker for Nanobody-Based Detection of Trypanosoma evansi. In: Vaccines, Vol. 8, no. 3, p. 415 (2020). doi:10.3390/vaccines8030415 (Accepté/Sous presse).
2020
Hussain, Nusrat ; Chuang, Sheng-Ju ; Johanns, Manuel ; Vertommen, Didier ; Steinberg, Gregory R ; Kemp, Bruce E ; Rider, Mark H.. Correction: Effects of PKB/Akt inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.. In: The Biochemical journal, Vol. 477, no.23, p. 4599-4601 (2020). doi:10.1042/BCJ-2019-0788_COR.
2020
Nguyen, Phuong N. ; Tossounian, Maria-Armineh ; Kovacs, Denes S. ; Thu, Tran T. ; Stijlemans, Benoit ; Vertommen, Didier ; Pauwels, Jarne ; Gevaert, Kris ; Angenon, Geert ; Messens, Joris ; Tompa, Peter. Dehydrin ERD14 activates glutathione transferase Phi9 in Arabidopsis thaliana under osmotic stress. In: Biochimica et biophysica acta. General subjects, Vol. 1864, no. 3, p. 129506 [1-11] (2020). doi:10.1016/j.bbagen.2019.129506.
2020
Perrin, Florian ; Papadopoulos, Nicolas ; Suelves Caballol, Nuria ; Opsomer, Remi ; Vadukul, Devkee Mahesh ; Vrancx, Céline ; Smith, Steven O. ; Vertommen, Didier ; Kienlen-Campard, Pascal ; Constantinescu, Stefan N.. Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization. In: iScience, Vol. 23, no. 12, p. 101887 [1-43] (2020). doi:10.1016/j.isci.2020.101887.
2020
Perrin, Florian ; Papadopoulos, Nicolas ; Suelves, Nuria ; Opsomer, Rémi ; Vadukul, Devkee M ; Vrancx, Céline ; Smith, Steven O ; Vertommen, Didier ; Kienlen-Campard, Pascal ; Constantinescu, Stefan N.. Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization.. In: iScience, Vol. 23, no.12, p. 101887 (2020). doi:10.1016/j.isci.2020.101887.
2020
Ouni, Emna ; Pyr dit Ruys, Sébastien ; Dolmans, Marie-Madeleine ; Herinckx, Gaëtan ; Vertommen, Didier ; Andrade Amorim, Christiani. Divide-and-Conquer Matrisome Protein (DC-MaP) Strategy: An MS-Friendly Approach to Proteomic Matrisome Characterization. In: International Journal of Molecular Sciences, Vol. 21, no. 23, p. 9141 [1-23] (2020). doi:10.3390/ijms21239141.
2020
Hussain, Nusrat ; Chuang, Sheng-Ju ; Johanns, Manuel ; Vertommen, Didier ; Steinberg, Gregory R ; Kemp, BruceE ; Rider, Mark H.. Effects of PKB/AKT inhibitors on insulin-stimulated lipogenesis and phosphorylation state of lipogenic enzymes in white adipose tissue.. In: The Biochemical journal, Vol. 477, no. 8, p. 1373-1389 (2020). doi:10.1042/BCJ20190788.
2020
Kopietz, Franziska ; Rupar, Kaja ; Berggreen, Christine ; Säll, Johanna ; Vertommen, Didier ; Degerman, Eva ; Rider, Mark H. ; Göransson, Olga. Inhibition of AMPK activity in response to insulin in adipocytes: involvement of AMPK pS485, PDEs, and cellular energy levels. In: American Journal of Physiology-Endocrinology and Metabolism, Vol. 319, no. 3, p. E459-E471 (2020). doi:10.1152/ajpendo.00065.2020.
2020
Murvai, Nikoletta ; Kalmar, Lajos ; Szalaine Agoston, Bianka ; Szabo, Beata ; Tantos, Agnes ; Csikos, Gyorgy ; Micsonai, András ; Kardos, József ; Vertommen, Didier ; Nguyen, Phuong N. ; Hristozova, Nevena ; Lang, Andras ; Kovacs, Denes ; Buday, Laszlo ; Han, Kyou-Hoon ; Perczel, Andras ; Tompa, Peter. Interplay of Structural Disorder and Short Binding Elements in the Cellular Chaperone Function of Plant Dehydrin ERD14. In: Cells, Vol. 9, no.8, p. 1856 (2020). doi:10.3390/cells9081856 (Accepté/Sous presse).
2020
Tossounian, Maria-Armineh ; Khanh Truong, Anh-Co ; Buts, Lieven ; Wahni, Khadija ; Mourenza, Álvaro ; Leermakers, Martine ; Vertommen, Didier ; Mateos, Luis Mariano ; Volkov, Alexander N ; Messens, Joris. Methionine sulfoxide reductase B from catalyzes sulfoxide reduction via an intramolecular disulfide cascade.. In: The Journal of biological chemistry, Vol. 295, no.11, p. 3664-3677 (2020). doi:10.1074/jbc.RA119.012438.
2020
Yang, Dong ; Vandenbussche, Guy ; Vertommen, Didier ; Evrard, Damien ; Abskharon, Romany ; Cavalier, Jean-François ; Berger, Gilles ; Canaan, Stéphane ; Khan, Mohammad Shahneawz ; Zeng, Sheng ; Wohlkönig, Alexandre ; Prévost, Martine ; Soumillion, Patrice ; Fontaine, Véronique. Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility.. In: FEBS letters, Vol. 594, no. 1, p. 79-93 (2020). doi:10.1002/1873-3468.13555.
2020
Gourgue, Florian ; Mignion, Lionel ; Van Hul, Matthias ; Dehaen, Natacha ; Bastien, Estelle ; Payen, Valery ; Leroy, Baptiste ; Joudiou, Nicolas ; Vertommen, Didier ; Bouzin, Caroline ; Delzenne, Nathalie M. ; Gallez, Bernard ; Feron, Olivier ; Jordan, Bénédicte ; Cani, Patrice D.. Obesity and triple-negative-breast-cancer: Is apelin a new key target?. In: Journal of cellular and molecular medicine, Vol. 24, p. 10233-44 (2020). doi:10.1111/jcmm.15639.
2020
van Caloen, Gabrielle ; Schmitz, Sandra ; El Baroudi, Mariama ; Caignet, Xavier ; Pyr dit Ruys, Sébastien ; Roger, Pierre P ; Vertommen, Didier ; Machiels, Jean-Pascal. Preclinical Activity of Ribociclib in Squamous Cell Carcinoma of the Head and Neck.. In: Molecular cancer therapeutics, Vol. 19, no. 3, p. 777-789 (2020). doi:10.1158/1535-7163.MCT-19-0695.
2020
Ouni, Emna ; Bouzin, Caroline ; Dolmans, Marie-Madeleine ; Marbaix, Etienne ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Andrade Amorim, Christiani. Spatiotemporal changes in mechanical matrisome components of the human ovary from prepuberty to menopause.. In: Human reproduction, Vol. 36, no. 6, p. 1391-1410 (2020). doi:10.1093/humrep/deaa100.
2020
Liu, Yang ; Nguyen, Phong T ; Wang, Xun ; Zhao, Yuting ; Meacham, Corbin E ; Zou, Zhongju ; Bordieanu, Bogdan ; Johanns, Manuel ; Vertommen, Didier ; Wijshake, Tobias ; May, Herman ; Xiao, Guanghua ; Shoji-Kawata, Sanae ; Rider, Mark H. ; Morrison, Sean J ; Mishra, Prashant ; Levine, Beth. TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise.. In: Nature, Vol. 578, no. 7796, p. 605-609 (2020). doi:10.1038/s41586-020-1992-7.
2019
Ouni, Emna ; Vertommen, Didier ; Chiti, Maria Costanza ; Dolmans, Marie-Madeleine ; Andrade Amorim, Christiani. A draft map of the human ovarian proteome for tissue engineering and clinical applications.. In: Molecular and Cellular Proteomics, Vol. 18, no. S1, p. S159-S173 (2019). doi:10.1074/mcp.RA117.000469.
2019
Spillier, Quentin ; Vertommen, Didier ; Séverine Ravez ; Marteau, Romain ; THÉMANS, Quentin ; Corbet, Cyril ; Feron, Olivier ; Wouters, Johan ; Frédérick, Raphaël. Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation. In: Scientific Reports, Vol. 9, no. 1, p. 4737 (2019).
2019
Lewandowska, Aleksandra ; Vo, Trung ; Nguyen, Thuy-Dung ; Wahni, Khadija ; Vertommen, Didier ; Van Breusegem, Frank ; Young, David ; Messens, Joris. Bifunctional Chloroplastic DJ-1B from Arabidopsis thaliana is an Oxidation-Robust Holdase and a Glyoxalase Sensitive to H2O2. In: Antioxidants, Vol. 8, no.1, p. 8 (2019). doi:10.3390/antiox8010008.
2019
Pecquet, Christian ; Chachoua, Ilyas ; Roy, Anita ; Balligand, Thomas ; Vertenoeil, Gaëlle ; Leroy, Emilie ; Albu, Roxana-Irina ; Defour, Jean-Philippe ; Nivarthi, Harini ; Hug, Eva ; Xu, Erica ; Ould Amer, Yasmine ; Mouton, Céline ; Colau, Didier ; Vertommen, Didier ; Shwe, Myat Marlar ; Marty, Caroline ; Plo, Isabelle ; Vainchenker, William ; Kralovics, Robert ; Constantinescu, Stefan N.. Calreticulin mutants as oncogenic rogue chaperones for TpoR and traffic-defective pathogenic TpoR mutants. In: Blood, Vol. 133, no. 25, p. 2669-2681 (2019). doi:10.1182/blood-2018-09-874578.
2019
Vermeulen, Maxime ; Del Vento, Federico ; Kanbar, Marc ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Poels, Jonathan ; Wyns, Christine. Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix. In: International Journal of Molecular Sciences, Vol. 20, no.21, p. 5476 [1-21] (2019). doi:10.3390/ijms20215476.
2019
Johanns, Manuel ; Kviklyté, Samanta ; Chuang, Sheng-Ju ; Corbeels, Katrien ; Jacobs, Roxane ; Herinckx, Gaëtan ; Vertommen, Didier ; Schakman, Olivier ; Duparc, Thibaut ; Cani, Patrice D. ; Bouzin, Caroline ; Andersén, Harriet ; Bohlooly-Y, Mohammad ; Van der Schueren, Bart ; Oscarsson, Jan ; Rider, Mark H.. Genetic deletion of soluble 5′-nucleotidase II reduces body weight gain and insulin resistance induced by a high-fat diet. In: Molecular Genetics and Metabolism, Vol. 126, no. 4, p. 377-387 (2019). doi:10.1016/j.ymgme.2019.01.017.
2019
Deneyer, Noémie ; Bridoux, Laure ; Bombled, Céline ; Pringels, Tamara ; Bergiers, Isabelle ; Pyr dit Ruys, Sébastien ; Vertommen, Didier ; Twizere, Jean-Claude ; Rezsohazy, René. HOXA2 activity regulation by cytoplasmic relocation, protein stabilization and post-translational modification. In: Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1862, no.9, p. 194404 (2019). doi:10.1016/j.bbagrm.2019.07.005.
2019
Marbaix, Alexandre ; Chehade, Georges ; Noël, Gaëtane ; Morsomme, Pierre ; Vertommen, Didier ; Bommer, Guido ; Van Schaftingen, Emile. Pyridoxamine-phosphate oxidases and pyridoxamine-phosphate oxidase-related proteins catalyze the oxidation of 6-NAD(P)H to NAD(P).. In: The Biochemical journal, Vol. 476, no.20, p. 3033-3052 (2019). doi:10.1042/BCJ20190602.
2019
Ouni, Emna ; Vertommen, Didier ; Andrade Amorim, Christiani. The Human Ovary and Future of Fertility Assessment in the Post-Genome Era. In: International Journal of Molecular Sciences, Vol. 20, no.17, p. 4209 (2019). doi:10.3390/ijms20174209.
2019
Choumessi Tchewonpi, Aphrodite ; Johanns, Manuel ; Beaufay, Claire ; Herent, Marie-France ; Stroobant, Vincent ; Vertommen, Didier ; Corbet, Cyril ; Jacobs, Roxane ; Herinckx, Gaëtan ; Steinberg, Gregory R ; Feron, Olivier ; Quetin-Leclercq, Joëlle ; Rider, Mark H.. Two isoprenylated flavonoids from Dorstenia psilurus activate AMPK, stimulate glucose uptake, inhibit glucose production and lower glycemia. In: Biochemical Journal, Vol. 476, no. 24, p. 3687-3704 (2019). doi:10.1042/BCJ20190326.
2018
Drappier, Melissa ; Jha, Babal Kant ; Stone, Sasha ; Elliott, Ruth ; Zhang, Rong ; Vertommen, Didier ; Weiss, Susan R ; Silverman, Robert H ; Michiels, Thomas. A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L.. In: PLoS pathogens, Vol. 14, no.4, p. e1006989 (2018). doi:10.1371/journal.ppat.1006989.
2018
Goemans, Camille V ; Vertommen, Didier ; Agrebi, Rym ; Collet, Jean-François. CnoX Is a Chaperedoxin: A Holdase that Protects Its Substrates from Irreversible Oxidation.. In: Molecular Cell, Vol. 70, no.4, p. 614-627.e7 (2018). doi:10.1016/j.molcel.2018.04.002.
2018
Pinto Torres, Joar E. ; Goossens, Julie ; Ding, Jianzu ; Li, Zeng ; Lu, Shaohong ; Vertommen, Didier ; Naniima, Peter ; Chen, Rui ; Muyldermans, Serge ; Sterckx, Yann G.-J. ; Magez, Stefan. Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections. In: Scientific Reports, Vol. 8, no.1, p. 9019 (2018). doi:10.1038/s41598-018-26732-7.
2018
Tossounian, Maria-Armineh ; Van Molle, Inge ; Wahni, Khadija ; Jacques, Silke ; Gevaert, Kris ; Van Breusegem, Frank ; Vertommen, Didier ; Young, David ; Rosado, Leonardo Astolfi ; Messens, Joris. Disulfide bond formation protects Arabidopsis thaliana glutathione transferase tau 23 from oxidative damage. In: Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1862, no. 3, p. 775-789 (2018). doi:10.1016/j.bbagen.2017.10.007.
2018
Degosserie, Jonathan ; Heymans, Charlotte ; Spourquet, Catherine ; Halbout, Mathias ; D'Auria, Ludovic ; Van Der Smissen, Patrick ; Vertommen, Didier ; Courtoy, Pierre J. ; Tyteca, Donatienne ; Pierreux, Christophe. Extracellular vesicles from endothelial progenitor cells promote thyroid follicle formation.. In: Journal of Extracellular Vesicles, Vol. 7, no.1, p. 1487250 [1-12] (2018). doi:10.1080/20013078.2018.1487250.
2018
Bollaert, Emeline ; Johanns, Manuel ; Herinckx, Gaëtan ; de Rocca Serra, Audrey ; Vandewalle, Virginie A ; Havelange, Violaine ; Rider, Mark H. ; Vertommen, Didier ; Demoulin, Jean-Baptiste. HBP1 phosphorylation by AKT regulates its transcriptional activity and glioblastoma cell proliferation.. In: Cellular Signalling, Vol. 44, p. 158-170 (2018). doi:10.1016/j.cellsig.2018.01.014.
2018
Wiame, Elsa ; Tahay, Gaëlle ; Tyteca, Donatienne ; Vertommen, Didier ; Stroobant, Vincent ; Bommer, Guido ; Van Schaftingen, Emile. NAT6 acetylates the N-terminus of different forms of actin.. In: The FEBS journal, Vol. 285, no. 17, p. 3299-3316 (2018). doi:10.1111/febs.14605.
2018
Tossounian, Maria‐Armineh ; Wahni, Khadija ; Van Molle, Inge ; Vertommen, Didier ; Astolfi Rosado, Leonardo ; Messens, Joris. Redox‐regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H‐site flexibility. In: Protein Science, Vol. 28, no.5, p. 56-67 (2018). doi:10.1002/pro.3440.
2018
Kwiatkowski, Sebastian ; Seliga, Agnieszka K ; Vertommen, Didier ; Terreri, Marianna ; Ishikawa, Takao ; Grabowska, Iwona ; Tiebe, Marcel ; Teleman, Aurelio A ; Jagielski, Adam K ; Veiga da Cunha, Maria ; Drozak, Jakub. SETD3 protein is the actin-specific histidine N-methyltransferase. In: eLife, Vol. 7, p. e37921 [1-42] (2018). doi:10.7554/elife.37921.
2018
Huang, Jingjing ; Niazi, Adnan Khan ; Young, David ; Rosado, Leonardo Astolfi ; Vertommen, Didier ; Bodra, Nandita ; Abdelgawwad, Mohamed Ragab ; Vignols, Florence ; Wei, Bo ; Wahni, Khadija ; Bashandy, Talaat ; Bariat, Laetitia ; Van Breusegem, Frank ; Messens, Joris ; Reichheld, Jean-Philippe. Self-protection of cytosolic malate dehydrogenase against oxidative stress in Arabidopsis. In: Journal of Experimental Botany, Vol. 69, no. 14, p. 3491-3505 (2018). doi:10.1093/jxb/erx396.
2018
Goemans, Camille V ; Beaufay, François ; Arts, Isabelle S ; Agrebi, Rym ; Vertommen, Didier ; Collet, Jean-François. The Chaperone and Redox Properties of CnoX Chaperedoxins Are Tailored to the Proteostatic Needs of Bacterial Species.. In: mBio, Vol. 9, no.6, p. 1-14 (2018). doi:10.1128/mBio.01541-18.