Publications
2024
Dorrazehi, Gol Mohammad ; Winkle, Matthias ; Desmet, Martin ; Stroobant, Vincent ; Tanriver, Gamze ; Degand, Hervé ; Evrard, Damien ; Desguin, Benoît ; Morsomme, Pierre ; Biboy, Jacob ; Gray, Joe ; Mitusińska, Karolina ; Góra, Artur ; Vollmer, Waldemar ; Soumillion, Patrice. PBP-A, a cyanobacterial DD-peptidase with high specificity for amidated muropeptides, exhibits pH-dependent promiscuous activity harmful to Escherichia coli.. In: Scientific reports, Vol. 14, no. 1, p. 13999 (2024). doi:10.1038/s41598-024-64806-x (Accepté/Sous presse).
2023
Meersseman Arango, Hippolyte ; van den Biggelaar, Ludivine ; Soumillion, Patrice ; Luis Alconero, Patricia ; Leyssens, Tom ; Paradisi, Francesca ; Debecker, Damien P.. Continuous flow-mode synthesis of (chiral) amines with transaminase: a strategic biocatalytic approach to essential building blocks. In: Reaction Chemistry & Engineering, Vol. 8, p. 1505–1544 (2023). doi:10.1039/d3re00210a.
2022
Knoops, Adrien ; Ledesma-García, Laura ; Waegemans, Alexandra ; Lamontagne, Morgane ; Decat, Baptiste ; Degand, Hervé ; Morsomme, Pierre ; Soumillion, Patrice ; Delvigne, Frank ; Hols, Pascal. Competence shut-off by intracellular pheromone degradation in salivarius streptococci. In: PLOS Genetics, Vol. 18, no.5, p. e1010198 (2022). doi:10.1371/journal.pgen.1010198.
2021
Yang, Jinsung ; Petitjean, Simon ; Koehler, Mélanie ; Zhang, Qingrong ; Dumitru, Andra-Cristina ; Chen, Wenzhang ; Derclaye, Sylvie ; Vincent, Stéphane P ; Soumillion, Patrice ; Alsteens, David. Author Correction: Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor.. In: Nature communications, Vol. 12, no.1, p. 2996 (2021). doi:10.1038/s41467-021-23498-x.
2021
Ledesma-García, Laura ; Ensinck, Imke ; Dereinne, Denis ; Viela Bovio, Felipe ; Mignolet, Johann ; Dufrêne, Yves ; Soumillion, Patrice ; Nessler, Sylvie ; Hols, Pascal. Co-evolution of the bacterial pheromone ComS and sensor ComR fine-tunes natural transformation in streptococci.. In: The Journal of biological chemistry, , p. 101346 (2021). doi:10.1016/j.jbc.2021.101346.
2021
Gargiulo, Serena ; Soumillion, Patrice. Directed evolution for enzyme development in biocatalysis.. In: Current opinion in chemical biology, Vol. 61, p. 107-113 (2021). doi:10.1016/j.cbpa.2020.11.006.
2021
Godessart, Pierre ; Lannoy, Adélie ; Dieu, Marc ; Van der Verren, Sander E ; Soumillion, Patrice ; Collet, Jean-François ; Remaut, Han ; Renard, Patricia ; De Bolle, Xavier. β-Barrels covalently link peptidoglycan and the outer membrane in the α-proteobacterium Brucella abortus.. In: Nature microbiology, Vol. 6, no.1, p. 27-33 (2021). doi:10.1038/s41564-020-00799-3.
2020
Yang, Dong ; Klebl, David P. ; Zeng, Sheng ; Sobott, Frank ; Prévost, Martine ; Soumillion, Patrice ; Vandenbussche, Guy ; Fontaine, Véronique. Interplays between copper and Mycobacterium tuberculosis GroEL1. In: Metallomics, (2020). doi:10.1039/d0mt00101e (Accepté/Sous presse).
2020
Yang, Dong ; Vandenbussche, Guy ; Vertommen, Didier ; Evrard, Damien ; Abskharon, Romany ; Cavalier, Jean-François ; Berger, Gilles ; Canaan, Stéphane ; Khan, Mohammad Shahneawz ; Zeng, Sheng ; Wohlkönig, Alexandre ; Prévost, Martine ; Soumillion, Patrice ; Fontaine, Véronique. Methyl arachidonyl fluorophosphonate inhibits Mycobacterium tuberculosis thioesterase TesA and globally affects vancomycin susceptibility.. In: FEBS letters, Vol. 594, no. 1, p. 79-93 (2020). doi:10.1002/1873-3468.13555.
2020
Ledesma-García, Laura ; Thuillier, Jordhan ; Guzman-Espinola, Armando ; Ensinck, Imke ; Li de la Sierra-Gallay, Inès ; Lazar, Noureddine ; Aumont-Nicaise, Magali ; Mignolet, Johann ; Soumillion, Patrice ; Nessler, Sylvie ; Hols, Pascal. Molecular dissection of pheromone selectivity in the competence signaling system ComRS of streptococci. In: Proceedings of the National Academy of Sciences, Vol. 117, no.14, p. 201916085 (2020). doi:10.1073/pnas.1916085117.
2020
Yang, Jinsung ; Petitjean, Simon ; Koehler, Mélanie ; Zhang, Qingrong ; Dumitru, Andra-Cristina ; Chen, Wenzhang ; Derclaye, Sylvie ; Vincent, Stéphane P. ; Soumillion, Patrice ; Alsteens, David. Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor. In: Nature Communications, Vol. 11, no. 1, p. 4541 (2020). doi:10.1038/s41467-020-18319-6.
2020
Khan, Mohammad Shahneawz ; Gargiulo, Serena ; Soumillion, Patrice. Promiscuous activity of 3-isopropylmalate dehydrogenase produced at physiological level affords Escherichia coli growth on d-malate.. In: FEBS letters, (2020). doi:10.1002/1873-3468.13814 (Accepté/Sous presse).
2020
Desguin, Benoît ; Urdiain-Arraiza, Julian ; Da Costa, Matthieu ; Fellner, Matthias ; Hu, Jian ; Hausinger, Robert P ; Desmet, Tom ; Hols, Pascal ; Soumillion, Patrice. Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.. In: Scientific reports, Vol. 10, no.1, p. 18123 (2020). doi:10.1038/s41598-020-74802-6.
2020
Art, Jean-François ; Soumillion, Patrice ; Dupont-Gillain, Christine C.. Use of a quartz crystal microbalance platform to study protein adsorption on aluminum hydroxide vaccine adjuvants: Focus on phosphate-hydroxide ligand exchanges. In: International Journal of Pharmaceutics, Vol. 573, p. 118834 (2020). doi:10.1016/j.ijpharm.2019.118834.
2019
van den Biggelaar, Ludivine ; Soumillion, Patrice ; Debecker, Damien P.. Biocatalytic transamination in a monolithic flow reactor: improving enzyme grafting for enhanced performance. In: RSC Advances, Vol. 9, no.32, p. 18538-18546 (2019). doi:10.1039/c9ra02433f.
2019
Köhler, Melanie ; Aravamudhan, Pavithra ; Guzman-Cardozo, Camila ; Dumitru, Andra-Cristina ; Yang, Jinsung ; Gargiulo, Serena ; Soumillion, Patrice ; Dermody, Terence S. ; Alsteens, David. Glycan-mediated enhancement of reovirus receptor binding. In: Nature Communications, Vol. 10, no. 1, p. 4460 (2019). doi:10.1038/s41467-019-12411-2.
2018
Desguin, Benoît ; Fellner, Matthias ; Riant, Olivier ; Hu, Jian ; Hausinger, Robert ; Hols, Pascal ; Soumillion, Patrice. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.. In: Journal of Biological Chemistry, (2018). doi:10.1074/jbc.RA118.003741.
2018
Crowet, Jean Marc ; Nasir, Mehmet Nail ; Dony, Nicolas ; Deschamps, Antoine ; Stroobant, Vincent ; Morsomme, Pierre ; Deleu, Magali ; Soumillion, Patrice ; Lins, Laurence. Insight into the Self-Assembling Properties of Peptergents: A Molecular Dynamics Simulation Study.. In: International Journal of Molecular Sciences (Print), Vol. 19, no.9, p. 2772 (2018). doi:10.3390/ijms19092772.
2020
Dorrazehi, Gol Mohammad ; Worms, Sebastian ; Chirakadavil, Jason Baby ; Mignolet, Johann ; Hols, Pascal ; Soumillion, Patrice. Building scarless gene libraries in the chromosome of bacteria. In: Iranzo, Olga, Roque, Ana Cecília, Springer Protocols – Peptide and Protein Engineering, From Concepts to Biotechnological Applications, 2020. 978-1-0716-0719-0 (Accepté/Sous presse).
2020
Urvoas, Agathe ; Minard, Philippe ; Soumillion, Patrice. Phage display methodologies. In: Iranzo, Olga, Roque, Ana Cecília, Springer Protocols – Peptide and Protein Engineering, From Concepts to Biotechnological Applications, 2020. 978-1-0716-0719-0 (Accepté/Sous presse).
2019
van den Biggelaar, Ludivine ; Gauchet, Adrien ; Khan, Mohammad Shahneawz ; Soumillion, Patrice ; Debecker, Damien P.. Flow mode enantioselective transamination using transaminase enzymes immobilized in a macroporous silica monolith. International Symposium on Green Chemistry (La Rochelle, France, du 13/05/2019 au 17/05/2019).
2018
Debecker, Damien P. ; van den Biggelaar, Ludivine ; Gauchet, Adrien ; Khan, Mohammad Shahneawz ; Soumillion, Patrice. Immobilizing transaminase in a macroporous silica monolith for flow mode enantioselective transamination . International Symposium on Relations between Homogeneous and Heterogeneous Catalysis (ISHHC18) (Sydney, Australia, du 22/07/2018 au 25/07/2018).
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