Publications
Publications
2019
Duchêne, Marie-Clémence ; Rolain, Thomas ; Knoops, Adrien ; Courtin, Pascal ; Chapot-Chartier, Marie-Pierre ; Dufrêne, Yves ; Hallet, Bernard ; Hols, Pascal. Distinct and Specific Role of NlpC/P60 Endopeptidases LytA and LytB in Cell Elongation and Division of .. In: Frontiers in microbiology, Vol. 10, p. 713 (2019). doi:10.3389/fmicb.2019.00713.
2019
Fléchard, Maud ; Lucchetti-Miganeh, Céline ; Hallet, Bernard ; Hols, Pascal ; Gilot, Philippe. Intensive targeting of regulatory competence genes by transposable elements in streptococci.. In: Molecular Genetics and Genomics : an international journal, Vol. 294, no. 3, p. 531-548 (2019). doi:10.1007/s00438-018-1507-5.
2019
Hols, Pascal ; Ledesma-García, Laura ; Gabant, Philippe ; Mignolet, Johann. Mobilization of Microbiota Commensals and Their Bacteriocins for Therapeutics. In: Trends in Microbiology, (2019). doi:10.1016/j.tim.2019.03.007.
2019
Mignolet, Johann ; Cerckel, Guillaume ; Damoczi, Julien ; Ledesma-Garcia, Laura ; Sass, Andrea ; Coenye, Tom ; Nessler, Sylvie ; Hols, Pascal. Subtle selectivity in a pheromone sensor triumvirate desynchronizes competence and predation in a human gut commensal.. In: eLife, Vol. 8 (2019). doi:10.7554/eLife.47139.
2018
Desguin, Benoît ; Fellner, Matthias ; Riant, Olivier ; Hu, Jian ; Hausinger, Robert ; Hols, Pascal ; Soumillion, Patrice. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.. In: Journal of Biological Chemistry, (2018). doi:10.1074/jbc.RA118.003741.
2018
Mignolet, Johann ; Fontaine, Laetitia ; Sass, Andrea ; Nannan, Catherine ; Mahillon, Jacques ; Coenye, Tom ; Hols, Pascal. Circuitry Rewiring Directly Couples Competence to Predation in the Gut Dweller Streptococcus salivarius. In: Cell Reports, Vol. 22, no. 7, p. 1627-1638 (2018). doi:10.1016/j.celrep.2018.01.055.
2018
David, Blandine ; Duchêne, Marie-Clémence ; Haustenne, Gabrielle Laurie ; Pérez-Núñez, Daniel ; Chapot-Chartier, Marie-Pierre ; De Bolle, Xavier ; Guédon, Eric ; Hols, Pascal ; Hallet, Bernard. PBP2b plays a key role in both peripheral growth and septum positioning in Lactococcus lactis.. In: PLoS One, Vol. 13, no.5, p. e0198014 (2018). doi:10.1371/journal.pone.0198014.
2018
Fernández Ramírez, Mónica D ; Nierop Groot, Masja N ; Smid, Eddy J ; Hols, Pascal ; Kleerebezem, Michiel ; Abee, Tjakko. Role of cell surface composition and lysis in static biofilm formation by Lactobacillus plantarum WCFS1.. In: International journal of food microbiology, Vol. 271, p. 15-23 (2018). doi:10.1016/j.ijfoodmicro.2018.02.013.
2017
David, Blandine ; Radziejwoski, Amandine ; Toussaint, Frédéric ; Fontaine, Laetitia ; Henry de Frahan, Marie ; Patout, Cédric ; van Dillen, Sabine ; Boyaval, Patrick ; Horvath, Philippe ; Fremaux, Christophe ; Hols, Pascal. Natural DNA transformation is functional in Lactococcus lactis ssp. cremoris KW2.. In: Applied and Environmental Microbiology, Vol. 83, no.16, p. e01074-17 (2017). doi:10.1128/AEM.01074-17 (Accepté/Sous presse).
2017
Desguin, Benoît ; Soumillion, Patrice ; Hausinger, Robert P. ; Hols, Pascal. Unexpected complexity in the lactate racemization system of lactic acid bacteria. In: FEMS Microbiology Reviews, Vol. 41, no. Supp_1, p. S71-S83 (2017 Aug 1). doi:10.1093/femsre/fux021.
2016
Mignolet, Johann ; Fontaine, Laetitia ; Kleerebezem, Michiel ; Hols, Pascal. Complete Genome Sequence of Streptococcus salivarius HSISS4, a Human Commensal Bacterium Highly Prevalent in the Digestive Tract. In: Genome Announcements, Vol. 4, no.1, p. e01637-15 (2016). doi:10.1128/genomeA.01637-15.
2016
Desguin, Benoît ; Soumillion, Patrice ; Hols, Pascal ; Hausinger, Robert P. Nickel-pincer cofactor biosynthesis involves LarB-catalyzed pyridinium carboxylation and LarE-dependent sacrificial sulfur insertion.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 113, no.20, p. 5598-5603 (2016). doi:10.1073/pnas.1600486113.
2016
Solopova, Ana ; Formosa, Cécile ; Courtin, Pascal ; Furlan, Sylviane ; Veiga, Patrick ; Péchoux, Christine ; Armalyte, Julija ; Sadauskas, Mikas ; Kok, Jan ; Hols, Pascal ; Dufrêne, Yves ; Kuipers, Oscar P. ; Chapot-Chartier, Marie-Pierre ; Kulakauskas, Saulius. Regulation of Cell Wall Plasticity by Nucleotide Metabolism in Lactococcus lactis. In: Journal of Biological Chemistry, Vol. 291, no.21, p. 11323-11336 (2016). doi:10.1074/jbc.M116.714303.
2016
Talagas, Antoine ; Fontaine, Laetitia ; Ledesma-Garca, Laura ; Mignolet, Johann ; Li de la Sierra-Gallay, Inès ; Lazar, Noureddine ; Aumont-Nicaise, Magali ; Federle, Michael J. ; Prehna, Gerd ; Hols, Pascal ; Nessler, Sylvie. Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS. In: PLoS Pathogens, Vol. 12, no.12, p. e1005980 (2016). doi:10.1371/journal.ppat.1005980.
2016
Colinet, Anne-Sophie ; Sengottaiyan, Palanivelu ; Deschamps, Antoine ; Colsoul, Marie-Lise ; Thines, Louise ; Demaegd, Didier ; Duchêne, Marie-Clémence ; Foulquier, François ; Hols, Pascal ; Morsomme, Pierre. Yeast Gdt1 is a Golgi-localized calcium transporter required for stress-induced calcium signaling and protein glycosylation.. In: Scientific Reports, Vol. 6, no.24282, p. 1-11 (2016). doi:10.1038/srep24282.
2015
Desguin, Benoît ; Zhang, Tuo ; Soumillion, Patrice ; Hols, Pascal ; Hu, Jian ; Hausinger, Robert P. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.. In: Science, Vol. 349, no.6243, p. 66-69 (2015). doi:10.1126/science.aab2272.
2015
Desguin, Benoît ; Goffin, Philippe ; Bakouche, Nordine ; Diman, Aurélie ; Viaene, Eric ; Dandoy, Damien ; Fontaine, Laetitia ; Hallet, Bernard ; Hols, Pascal. Enantioselective regulation of lactate racemization by LarR in Lactobacillus plantarum.. In: Journal of Bacteriology, Vol. 197, no.1, p. 219-230 (2015). doi:10.1128/JB.02192-14.
2015
El Kirat, Sofiane ; Beaussart, Audrey ; Vincent, Stéphane P. ; Abellan Flos, Marta ; Hols, Pascal ; Lipke, Peter N. ; Dufrêne, Yves. Forces in yeast flocculation. In: Nanoscale, Vol. 7, no. 5, p. 1760-1767 (2015). doi:10.1039/c4nr06315e.
2015
Haustenne, Laurie ; Bastin, Georges ; Hols, Pascal ; Fontaine, Laetitia. Modeling of the ComRS Signaling Pathway Reveals the Limiting Factors Controlling Competence in Streptococcus thermophilus. In: Frontiers in Microbiology, Vol. 6, p. paper 1413 (2015). doi:10.3389/fmicb.2015.01413.
2015
Fontaine, Laetitia ; Wahl, Astrid ; Fléchard, Maud ; Mignolet, Johann ; Hols, Pascal. Regulation of competence for natural transformation in streptococci.. In: Infection, Genetics and Evolution, Vol. 1348, no. 33, p. 343-360 (2015). doi:10.1016/j.meegid.2014.09.010.
2014
Wahl, Astrid ; Servais, Florence ; Drucbert, Anne-Sophie ; Foulon, Catherine ; Fontaine, Laetitia ; Hols, Pascal. Control of natural transformation in salivarius Streptococci through specific degradation of σX by the MecA-ClpCP protease complex.. In: Journal of Bacteriology, Vol. 196, no.15, p. 2807-2816 (2014). doi:10.1128/JB.01758-14.
2014
Lee, I-Chiao ; van Swam, Iris I ; Tomita, Satoru ; Morsomme, Pierre ; Rolain, Thomas ; Hols, Pascal ; Kleerebezem, Michiel ; Bron, Peter A. GtfA and GtfB are both required for protein O-glycosylation in Lactobacillus plantarum.. In: Journal of Bacteriology, Vol. 196, no. 9, p. 1671-1682 (2014). doi:10.1128/JB.01401-13.
2014
Desguin, Benoît ; Goffin, Philippe ; Viaene, Eric ; Kleerebezem, Michiel ; Martin-Diaconescu, Vlad ; Maroney, Michael J ; Declercq, Jean-Paul ; Soumillion, Patrice ; Hols, Pascal. Lactate racemase is a nickel-dependent enzyme activated by a widespread maturation system.. In: Nature Communications, Vol. 5, p. 3615 (2014). doi:10.1038/ncomms4615.
2014
Beaussart, Audrey ; Péchou, Christine ; Trieu-Cuot, Patrick ; Hols, Pascal ; Mistou, Michel-Yves ; Dufrêne, Yves. Molecular mapping of the cell wall polysaccharides of the human pathogen Streptococcus agalactiae. In: Nanoscale, Vol. 6, p. 14820–14827 (2014). doi:10.1039/c4nr05280c.
2013
Beaussart, Audrey ; Rolain, Thomas ; Duchêne, Marie-Clémence ; El Kirat, Sofiane ; Andre, Guillaume ; Hols, Pascal ; Dufrêne, Yves. Binding mechanism of the peptidoglycan hydrolase Acm2: low affinity, broad specificity. In: Biophysical Journal, Vol. 105, no.3, p. 620-629 (2013). doi:10.1016/j.bpj.2013.06.035.
2013
Bienert, Gerd Patrick ; Desguin, Benoît ; Chaumont, François ; Hols, Pascal. Channel-mediated lactic acid transport: a novel function for aquaglyceroporins in bacteria. In: Biochemical Journal, Vol. 454, no. 3, p. 559-570 (2013). doi:10.1042/BJ20130388.
2013
Gardan, Rozenn ; Besset, Colette ; Gitton, Christophe ; Guillot, Alain ; Fontaine, Laetitia ; Hols, Pascal ; Monnet, Véronique. Extracellular life cycle of ComS, the competence-stimulating peptide of Streptococcus thermophilus.. In: Journal of bacteriology, Vol. 195, no.8, p. 1845-55 (2013). doi:10.1128/JB.02196-12.
2013
Herman, Philippe ; El Kirat, Sofiane ; Beaussart, Audrey ; Geoghegan, J.A. ; Vanzieleghem, Thomas ; Foster, T.J. ; Hols, Pascal ; Mahillon, Jacques ; Dufrêne, Yves. Forces driving the attachment of staphylococcus epidermidis to fibrinogen-coated surfaces. In: Langmuir : the A C S journal of surfaces and colloids, Vol. 29, no.42, p. 13018-13022 (2013). doi:10.1021/la4029172.
2013
Tian, Xiao-Lin ; Dong, Gaofeng ; Liu, Tianlei ; Gomez, Zubelda A ; Wahl, Astrid ; Hols, Pascal ; Li, Yung-Hua. MecA protein acts as a negative regulator of genetic competence in Streptococcus mutans.. In: Journal of bacteriology, Vol. 195, no.22, p. 5196-206 (2013). doi:10.1128/JB.00821-13.
2013
Fontaine, Laetitia ; Goffin, Philippe ; Dubout, Hélène ; Delplace, Brigitte ; Baulard, Alain ; Lecat-Guillet, Nathalie ; Chambellon, Emilie ; Gardan, Rozenn ; Hols, Pascal. Mechanism of competence activation by the ComRS signalling system in streptococci. In: Molecular Microbiology, Vol. 87, no.6, p. 1113-1132 (2013). doi:10.1111/mmi.12157.
2013
Tsuji, Akira ; Okada, Sanae ; Hols, Pascal ; Satoh, Eiichi. Metabolic engineering of Lactobacillus plantarum for succinic acid production through activation of the reductive branch of the tricarboxylic acid cycle.. In: Enzyme and microbial technology, Vol. 53, no.2, p. 97-103 (2013). doi:10.1016/j.enzmictec.2013.04.008.
2013
Rolain, Thomas ; Bernard, Elvis ; Beaussart, Audrey ; Degand, Hervé ; courtin, Pascal ; Egge-Jacobsen, Wolfgang ; Bron, Peter A. ; Morsomme, Pierre ; Kleerebezem, Michiel ; Chapot-Chartier, Marie-Pierre ; Dufrêne, Yves ; Hols, Pascal. O-glycosylation as a novel control mechanism of peptidoglycan hydrolase activity. In: Journal of Biological Chemistry, Vol. 288, no. 31, p. 22233-22247 (2013). doi:10.1074/jbc.M113.470716.
2013
Boutry, Céline ; Delplace, Brigitte ; Clippe, André ; Fontaine, Laetitia ; Hols, Pascal. SOS response activation and competence development are antagonistic mechanisms in Streptococcus thermophilus.. In: Journal of bacteriology, Vol. 195, no. 4, p. 696-707 (2013). doi:10.1128/JB.01605-12.
2013
Beaussart, Audrey ; El Kirat, Sofiane ; Herman, Philippe ; Alsteens, David ; Mahillon, Jacques ; Hols, Pascal ; Dufrêne, Yves. Single-Cell Force Spectroscopy of Probiotic Bacteria. In: Biophysical Journal, Vol. 104, p. 1886-1892 (2013). doi:10.1016/j.bpj.2013.03.046.
2013
Meyrand, Mickael ; Guillot, Alain ; Goin, Mélodie ; Furlan, Sylviane ; Armalyte, Julija ; Kulakauskas, Saulius ; Cortes-Perez, Naima G ; Thomas, Ginette ; Chat, Sophie ; Péchoux, Christine ; Dupres, Vincent ; Hols, Pascal ; Dufrêne, Yves ; Trugnan, Germain ; Chapot-Chartier, Marie-Pierre. Surface proteome analysis of a natural isolate of Lactococcus lactis reveals the presence of pili able to bind human intestinal epithelial cells.. In: Molecular & cellular proteomics : MCP, Vol. 12, no. 12, p. 3935-47 (2013). doi:10.1074/mcp.M113.029066.
2012
Boutry, Céline ; Wahl, Astrid ; Delplace, Brigitte ; Clippe, André ; Fontaine, Laetitia ; Hols, Pascal. Adaptor protein MecA is a negative regulator of the expression of late competence genes in Streptococcus thermophilus.. In: Journal of bacteriology, Vol. 194, no. 7, p. 1777-88 (2012). doi:10.1128/JB.06800-11.
2012
Regulski, Krzysztof ; Courtin, Pascal ; Meyrand, Mickael ; Claes, Ingmar J.J. ; Lebeer, Sarah ; Vanderleyden, Jos ; Hols, Pascal ; Guillot, Alain ; Chapot-Chartier, Marie-Pierre. Analysis of the peptidoglycan hydrolase complement of Lactobacillus casei and characterization of the major γ-D-glutamyl-L-lysyl-endopeptidase.. In: PLoS One, Vol. 7, no. 2, p. e32301 (2012). doi:10.1371/journal.pone.0032301.
2012
Bernard, Elvis ; Rolain, Thomas ; David, Blandine ; André, Guillaume ; Dupres, Vincent ; Dufrêne, Yves ; Hallet, Bernard ; Chapot-Chartier, Marie-Pierre ; Hols, Pascal. Dual Role for the O-Acetyltransferase OatA in Peptidoglycan Modification and Control of Cell Septation in Lactobacillus plantarum.. In: PLoS One, Vol. 7, p. e47893 (2012). doi:10.1371/journal.pone.0047893.
2012
Claes, Ingmar J.J. ; Schoofs, Geert ; Regulski, Krzysztof ; Courtin, Pascal ; Chapot-Chartier, Marie-Pierre ; Rolain, Thomas ; Hols, Pascal ; von Ossowski, Ingemar ; Reunanen, Justus ; de Vos, Willem M ; Palva, Airi ; Vanderleyden, Jos ; De Keersmaecker, Sigrid C J ; Lebeer, Sarah. Genetic and biochemical characterization of the cell wall hydrolase activity of the major secreted protein of Lactobacillus rhamnosus GG.. In: PLoS One, Vol. 7, no. 2, p. e31588 (2012). doi:10.1371/journal.pone.0031588.
2012
Rolain, Thomas ; Bernard, Elvis ; Courtin, Pascal ; Bron, Peter A ; Kleerebezem, Michiel ; Chapot-Chartier, Marie-Pierre ; Hols, Pascal. Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of Lactobacillus plantarum WCFS1.. In: Microbial cell factories, Vol. 11, no. 1, p. 137 (2012). doi:10.1186/1475-2859-11-137.
2012
Tripathi, Prachi ; Beaussart, Audrey ; André, Guillaume ; Rolain, Thomas ; Lebeer, S. ; Vanderleyden, J. ; Hols, Pascal ; Dufrêne, Yves. Towards a nanoscale view of lactic acid bacteria. In: Micron, Vol. 43, p. 1323-1330 (2012). doi:10.1016/j.micron.2012.01.001.
2011
Pérez-Núñez, Daniel ; Briandet, Romain ; David, Blandine ; Gautier, Céline ; Renault, Pierre ; Hallet, Bernard ; Hols, Pascal ; Carballido-López, Rut ; Guédon, Eric. A new morphogenesis pathway in bacteria : unbalanced activity of cell wall synthesis machineries leads to coccus-to-rod transition and filamentation in ovococci.. In: Molecular microbiology, Vol. 79, no. 3, p. 759-71 (2011). doi:10.1111/j.1365-2958.2010.07483.x.
2011
Bernard, Elvis ; Rolain, Thomas ; Courtin, Pascal ; Guillot, Alain ; Langella, Philippe ; Hols, Pascal ; Chapot-Chartier, Marie-Pierre. Characterization of O-acetylation of N-acetylglucosamine : a novel structural variation of bacterial peptidoglycan.. In: The Journal of biological chemistry, Vol. 286, no. 27, p. 23950-8 (2011). doi:10.1074/jbc.M111.241414.
2011
André, Guillaume ; Deghorain, Marie ; Bron, Peter A. ; van Swam, Iris I. ; Kleerebezem, Michiel ; Hols, Pascal ; Dufrêne, Yves. Fluorescence and Atomic Force Microscopy Imaging of Wall Teichoic Acids in Lactobacillus plantarum. In: ACS Chemical Biology, Vol. 6, no. 4, p. 366-376 (2011). doi:10.1021/cb1003509.
2011
Bernard, Elvis ; Rolain, Thomas ; Courtin, Pascal ; Hols, Pascal ; Chapot-Chartier, Marie-Pierre. Identification of the amidotransferase AsnB1 as being responsible for meso-diaminopimelic acid amidation in Lactobacillus plantarum peptidoglycan.. In: Journal of bacteriology, Vol. 193, no. 22, p. 6323-30 (2011). doi:10.1128/JB.05060-11.
2011
Capozzi, Vittorio ; Weidmann, Stéphanie ; Fiocco, Daniela ; Rieu, Aurélie ; Hols, Pascal ; Guzzo, Jean ; Spano, Giuseppe. Inactivation of a small heat shock protein affects cell morphology and membrane fluidity in Lactobacillus plantarum WCFS1.. In: Research in Microbiology, Vol. 162, no. 4, p. 419-425 (2011). doi:10.1016/j.resmic.2011.02.010.
2011
Storelli, Gilles ; Defaye, Arnaud ; Erkosar, Berra ; Hols, Pascal ; Royet, Julien ; Leulier, François. Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing.. In: Cell metabolism, Vol. 14, no. 3, p. 403-14 (2011). doi:10.1016/j.cmet.2011.07.012.
2011
Fleuchot, Betty ; Gitton, Christophe ; Guillot, Alain ; Vidic, J. ; Nicolas, P. ; Besset, Colette ; Fontaine, Laetitia ; Hols, Pascal ; Leblond-Bourget, Nathalie ; Monnet, Véronique ; Gardan, Rozenn. Rgg proteins associated with internalized small hydrophobic peptides: a new quorum-sensing mechanism in streptococci. In: Molecular Microbiology, Vol. 80, no. 4, p. 1102-119 (2011). doi:10.1111/j.1365-2958.2011.07633.x.
2011
Dandoy, Damien ; Fremaux, Christophe ; de Frahan, Marie Henry ; Horvath, Philippe ; Boyaval, Patrick ; Hols, Pascal ; Fontaine, Laetitia. The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS.. In: Microbial Cell Factories, Vol. 10 Suppl 1, p. S21 (2011). doi:10.1186/1475-2859-10-S1-S21.
2010
Fontaine, Laetitia ; Boutry, Céline ; Henry de Frahan, Marie ; Delplace, Brigitte ; Fremaux, Christophe ; Horvath, Philippe ; Boyaval, Patrick ; Hols, Pascal. A novel pheromone quorum-sensing system controls the development of natural competence in Streptococcus thermophilus and Streptococcus salivarius.. In: Journal of bacteriology, Vol. 192, no. 5, p. 1444-54 (2010). doi:10.1128/JB.01251-09.
2010
Chapot-Chartier, Marie-Pierre ; Vinogradov, Evgeny ; Sadovskaya, Irina ; André, Guillaume ; Mistou, Michel-Yves ; Trieu-Cuot, Patrick ; Furlan, Sylviane ; Bidnenko, Elena ; Courtin, Pascal ; Pechoux, Christine ; Hols, Pascal ; Dufrêne, Yves ; Kulakauskas, Saulius. Cell Surface of Lactococcus lactis Is Covered by a Protective Polysaccharide Pellicle. In: Journal of Biological Chemistry, Vol. 285, no. 14, p. 10464-10471 (2010). doi:10.1074/jbc.M109.082958.
2010
Fiocco, Daniela ; Capozzi, Vittorio ; Collins, Michael ; Gallone, Anna ; Hols, Pascal ; Guzzo, Jean ; Weidmann, Stephanie ; Rieu, Aurélie ; Msadek, Tarek ; Spano, Giuseppe. Characterization of the CtsR stress response regulon in Lactobacillus plantarum.. In: Journal of bacteriology, Vol. 192, no. 3, p. 896-900 (2010). doi:10.1128/JB.01122-09.
2010
Fontaine, Laetitia ; Dandoy, Damien ; Boutry, Céline ; Delplace, Brigitte ; de Frahan, Marie Henry ; Fremaux, Christophe ; Horvath, Philippe ; Boyaval, Patrick ; Hols, Pascal. Development of a versatile procedure based on natural transformation for marker-free targeted genetic modification in Streptococcus thermophilus.. In: Applied and environmental microbiology, Vol. 76, no. 23, p. 7870-7 (2010). doi:10.1128/AEM.01671-10.
2010
Deghorain, Marie ; Fontaine, Laetitia ; David, Blandine ; Mainardi, Jean-Luc ; Courtin, Pascal ; Daniel, Richard ; Errington, Jeff ; Sorokin, Alexei ; Bolotin, Alexander ; Chapot-Chartier, Marie-Pierre ; Hallet, Bernard ; Hols, Pascal. Functional and morphological adaptation to peptidoglycan precursors alteration in Lactococcus lactis.. In: The Journal of biological chemistry, Vol. 285, no. 31, p. 24003-13 (2010). doi:10.1074/jbc.M110.143636.
2010
André, Guillaume ; Kulakauskas, Saulius ; Chapot-Chartier, Marie-Pierre ; Navet, Benjamine ; Deghorain, Marie ; Bernard, Elvis ; Hols, Pascal ; Dufrêne, Yves. Imaging the nanoscale organization of peptidoglycan in living Lactococcus lactis cells.. In: Nature Communications, Vol. 1, no. 13, p. 1-8 (2010). doi:10.1038/ncomms1027.
2010
Kleerebezem, Michiel ; Hols, Pascal ; Bernard, Elvis ; Rolain, Thomas ; Zhou, Miaomiao ; Siezen, Roland J. ; Bron, Peter A.. The extracellular biology of the lactobacilli. In: FEMS Microbiology Reviews, Vol. 34, no. 2, p. 199-230 (2010). doi:10.1111/j.1574-6976.2010.00208.x.
2017
Desguin, Benoît ; Soumillion, Patrice ; Hols, Pascal ; Hu, Jian ; Hausinger, Robert P.. Lactate Racemase and Its Niacin-Derived, Covalently-Tethered, Nickel Cofactor. In: Deborah Zamble, Magdalena Rowińska-Żyrek, Henryk Kozłowski, The Biological Chemistry of Nickel (Metallobiology Series; 10), The Royal Society of Chemistry, 2017. 978-1-78262-498-1. doi:10.1039/9781788010580.
2011
Hugenholtz, Jeroen ; Hols, Pascal ; Snoep, Jacky. Metabolic engineering of lactic acid bacteria. In: Ledeboer A., Hugenholtz J., Kok J., Konings W., Wouters J., The 10th Lab Symposium. Thirty Years of Research on Lactic Acid Bacteria, Media Labs: Rotterdam, The Netherlands, 2011, p. 196. 978-90-817671-0-1.
2017
Mignolet, Johann ; Hols, Pascal. Ubiquitous rewiring of transcriptional control in streptococci: lesson from competence and predation coupling in Streptococcus salivarius.. 12th Symposium on Lactic Acid Bacteria (Egmond aan Zzee, du 27/08/2017 au 31/08/2017).
2017
Mignolet, Johann ; Fontaine, Laetitia ; Hols, Pascal. Ubiquitous rewiring of transcriptional control in streptococci: lessons from competence and predation coupling in Streptococcus salivarius. 19th International Conference on Bacilli and other Gram-Positive Bacteria (Berlin, DE, du 11/06/2017 au 15/06/2017).
2015
Mignolet, Johann. Cross-talk mediated by Rgg-peptide cell-cell communication systems from Streptococcus salivarius.. 8th International Conference on Gram-positive Microorganisms and 18th International Conference on Bacilli (Montecatini terme, Italy, du 21/06/2015 au 25/06/2015).
2015
Haustenne, Laurie ; Bastin, Georges ; Coron, Jean-Michel ; Fontaine, Laetitia ; Hols, Pascal. On stability analysis of genetic regulatory networks represented by delay-differential equations. 8th Vienna International Conference on Mathematical Modelling (Vienna, Austria, February 2015). In: Proceedings of Mathmod 2015, IFAC-PapersOnLine Vol. 48, n°1, 2015, 453-457. doi:10.1016/j.ifacol.2015.05.108.
2013
Haustenne, Laurie ; Bastin, Georges ; Wahl, Astrid ; Delplace, Brigitte ; Fontaine, Laetitia ; Hols, Pascal. Mathematical Modelling of the Gene Regulatory Network Governing Natural Transformation in Streptococcus thermophilus. 7th Conference on Functional Genomics of Gram-positive Microorganisms (Montecatini Terme, Italy, du 23/06/2013 au 27/06/2013).
2011
Fontaine, Laetitia ; Hols, Pascal. ComRS-dependent activation of natural competence in Streptococci. 10th International Symposium on Lactic Acid Bacteria (Amsterdam (Egmond Aan de Zee), The Netherlands, du 08/2011 au 09/2011).
2011
Fontaine, Laetitia ; Dubout, Hélène ; Dandoy, Damien ; Delplace, Brigitte ; Clippe, André ; Baulard, Alain ; Guillet, Nathalie ; Monnet, Véronique ; Gardan, Rozenn ; Hols, Pascal. Natural transformation in Streptococcus thermophilus: from regulation to application. 10th Symposium on lactic Acid bacterium (Egmond aan Zee, the Netherlands, du 28/08/2011 au 01/09/2011).
2018
Fremaux, Christophe ; Horvath, Philippe ; Boyaval, Patrick ; Hols, Pascal ; David, Blandine ; Radziejwoski, Amandine ; Fontaine, Laetitia ; Toussaint, Frédéric. A method for transforming a strain of the Lactococcus genus by natural competence. Numéro de priorité. .
2018
Mignolet, Johann ; Ledesma, Laura ; Hols, Pascal. Peptides for inducing bacteriocin synthesis and methods to identify and/ or select and/or optimize the same. Numéro de priorité ; Déposé (22 November 2018). EUR.
2013
Glénisson, Wendy ; Prozzi, Deborah ; Hols, Pascal. Method for modifying sporolactobacillus species by genetic engineering. .
2010
Boyaval, Patrick ; Fremaux, Christophe ; Hols, Pascal ; Fontaine, Laetitia ; Horvat, Philippe. A method for transforming a bacterium belonging to the streptococcus genus by natural competence. Numéro de priorité ; Déposé ; Publié (2010-12-29). WO WO.
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