Publications
2022
Gatreddi, Santhosh ; Urdiain-Arraiza, Julian ; Desguin, Benoît ; Hausinger, Robert P. ; Hu, Jian. Structural and mutational characterization of a malate racemase from the LarA superfamily. In: BioMetals, (2022). doi:10.1007/s10534-022-00372-x (Soumis).
2021
Rankin, Joel A ; Chatterjee, Shramana ; Tariq, Zia ; Lagishetty, Satyanarayana ; Desguin, Benoît ; Hu, Jian ; Hausinger, Robert P. The LarB carboxylase/hydrolase forms a transient cysteinyl-pyridine intermediate during nickel-pincer nucleotide cofactor biosynthesis.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 118, no.39, p. e2106202118 (2021). doi:10.1073/pnas.2106202118.
2020
Desguin, Benoît ; Urdiain-Arraiza, Julian ; Da Costa, Matthieu ; Fellner, Matthias ; Hu, Jian ; Hausinger, Robert P ; Desmet, Tom ; Hols, Pascal ; Soumillion, Patrice. Uncovering a superfamily of nickel-dependent hydroxyacid racemases and epimerases.. In: Scientific reports, Vol. 10, no.1, p. 18123 (2020). doi:10.1038/s41598-020-74802-6.
2018
Fellner, Matthias ; Rankin, Joel A ; Desguin, Benoît ; Hu, Jian ; Hausinger, Robert P. Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum.. In: Biochemistry, Vol. 57, no.38, p. 5513-5523 (2018). doi:10.1021/acs.biochem.8b00601.
2018
Desguin, Benoît ; Fellner, Matthias ; Riant, Olivier ; Hu, Jian ; Hausinger, Robert ; Hols, Pascal ; Soumillion, Patrice. Biosynthesis of the nickel-pincer nucleotide cofactor of lactate racemase requires a CTP-dependent cyclometallase.. In: Journal of Biological Chemistry, (2018). doi:10.1074/jbc.RA118.003741.
2018
Rankin, Joel A ; Mauban, Robert C ; Fellner, Matthias ; Desguin, Benoît ; McCracken, John ; Hu, Jian ; Varganov, Sergey A ; Hausinger, Robert P. Lactate Racemase Nickel-Pincer Cofactor Operates by a Proton-Coupled Hydride Transfer Mechanism.. In: Biochemistry, Vol. 57, no.23, p. 3244-3251 (2018). doi:10.1021/acs.biochem.8b00100.
2018
Desguin, Benoit. Lactate Racemization and Beyond. In: Journal of Bacteriology & Parasitology, Vol. 09, no. 02 (2018) (2018). doi:10.4172/2155-9597.1000335.
2017
Fellner, Matthias ; Desguin, Benoît ; Hausinger, Robert P ; Hu, Jian. Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.. In: Proceedings of the National academy of sciences of the United States of America, Vol. 114, p. 9074-9079 (2017). doi:10.1073/pnas.1704967114.
2017
Desguin, Benoît ; Soumillion, Patrice ; Hausinger, Robert P. ; Hols, Pascal. Unexpected complexity in the lactate racemization system of lactic acid bacteria. In: FEMS Microbiology Reviews, Vol. 41, no. Supp_1, p. S71-S83 (2017 Aug 1). doi:10.1093/femsre/fux021.
2020
Desguin, Benoît. LarC Cyclometallase. In: Robert A Scott, John Wiley & Sons, Encyclopedia of Inorganic and Bioinorganic Chemistry, 2020. 9781119951438. doi:10.1002/9781119951438.eibc2737.
2017
Desguin, Benoît ; Soumillion, Patrice ; Hols, Pascal ; Hu, Jian ; Hausinger, Robert P.. Lactate Racemase and Its Niacin-Derived, Covalently-Tethered, Nickel Cofactor. In: Deborah Zamble, Magdalena Rowińska-Żyrek, Henryk Kozłowski, The Biological Chemistry of Nickel (Metallobiology Series; 10), The Royal Society of Chemistry, 2017. 978-1-78262-498-1. doi:10.1039/9781788010580.
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