Technical and scientific expertise
- Animal welfare expertise and advice for the different housed species (Animal Welfare Units)
- Expertise in the breeding of single or multiple transgenic lines
- Model expertise:
- conditional mutagenesis, Cre/LoxP and CreERT2/LoxP approaches
- CRISPR/Cas9 knock-in or knock-out mice
- Breeding of fish models such as zebrafish (Danio rerio) and African turquoise killifish (Nothobranchius furzeri), and of an amphibian species (Xenopus laevis)
Main equipment
Conventional animal housing facility for housing, breeding and testing rodents and fish.
Rodents: classic animal housing facility with conventional open cages and a capacity of 1,000 individuals
- Seven rooms for breeding and rearing, one room for experimental procedures, one room for quarantine
- Twenty-five unique transgenic mouse lines
Fish: 100 polycarbonate and 48 glass aquariums, accommodating up to 1,500 individuals
- Zebrafish (Danio rerio)
- Turquoise killifish (Nothobranchius furzeri)
Amphibians
- African clawed frog (Xenopus laevis)
Take a look at the platform's infrastructure.
Applications
- Basic and translational research in developmental biology, neurobiology, inflammation and oncology
- Study of issues related to obesity, metabolic diseases, anti-cancer properties of certain fatty acids, underlying mechanisms of ageing and the function of aquaporins
Services available to
- UCLouvain students and researchers
- UCLouvain partner university researchers