Animal facilities (ANCA)

PFTPLUS

Mouse and its young © Ludwig Marion   African clawed frog © Ludwig Marion   Turquoise killifish © Ludwig Marion   Zebrafish © Ludwig Marion   Mouse © Ludwig Marion

Technical and scientific expertise

  • Animal welfare expertise and advice for the different housed species (Animal Welfare Units)
  • Expertise in the breeding of single or multiple transgenic lines
  • Model expertise:
    • conditional mutagenesis, Cre/LoxP and CreERT2/LoxP approaches
    • CRISPR/Cas9 knock-in or knock-out mice
  • Breeding of fish models such as zebrafish (Danio rerio) and African turquoise killifish (Nothobranchius furzeri), and of an amphibian species (Xenopus laevis)

Main equipment

Conventional animal housing facility for housing, breeding and testing rodents and fish.

Rodents: classic animal housing facility with conventional open cages and a capacity of 1,000 individuals

  • Seven rooms for breeding and rearing, one room for experimental procedures, one room for quarantine
  • Twenty-five unique transgenic mouse lines

Fish: 100 polycarbonate and 48 glass aquariums, accommodating up to 1,500 individuals

  • Zebrafish (Danio rerio)
  • Turquoise killifish (Nothobranchius furzeri)

Amphibians

  • African clawed frog (Xenopus laevis)

Take a look at the platform's infrastructure.

Applications

  • Basic and translational research in developmental biology, neurobiology, inflammation and oncology
  • Study of issues related to obesity, metabolic diseases, anti-cancer properties of certain fatty acids, underlying mechanisms of ageing and the function of aquaporins

Services available to

  • UCLouvain students and researchers
  • UCLouvain partner university researchers

News

ANCA: a new infrastructure by 2025 !

After years of discussions and planning, construction of the new infrastructure that will house the ANCA platform began at the end of 2023 on the site of the former greenhouses. Work began in...

ANCA : new equipment to improve animal welfare and...

A convention signed between UCLouvain and Wallonia, as part of the upgrading of accredited animal facilities, has enabled the ANCA platform to acquire new equipment to improve the welfare of the...

Alzheimer's disease: a fish as the main experimental model

Melissa Page (LIBST - BNTE) was awarded by the the Alzheimer’s Research Foundation (Fondation Recherche Alzheimer) in support of her research on cellular ageing in the brain and its potential...