Mass spectrometry of metabolites and compounds of pharmaceutical and biological interest (MASSMET)


LTQ–ORBITRAP XL (THERMOFISHER SCIENTIFIC)   Identification of secondary metabolites in plant extracts by HPLC-LTQ-Orbitrap XL HRMS and molecular networks   Xevo TQ-S UPLC-MS/MS (WATERS)   Xevo TQ-S UPLC-MS/MS (WATERS): Source   Identification of fatty acyl chains of phospholipids by UPLC-MS/MS

Technical and scientific expertise

  • Quantitative analysis of endogenous and exogenous molecules in biological matrices
  • Recognised expertise in lipid mediators and secondary plant metabolites (quantification, structural identification, etc.)
  • Complete development of chromatographic methods coupled with mass spectrometric detection
  • Validation of chromatographic methods (LC-MS, LC-UV, etc.)
  • Support for data interpretation and project/manuscript writing

Main equipment

  • High-resolution mass spectrometer coupled with a liquid chromatography system (UHPLC-HRMS LTQ-Orbitrap XL)
  • High-sensitivity mass spectrometer coupled with a liquid chromatography system (UHPLC-MS/MS Xevo TQ-S)
  • Several chromatographic systems (HPLC, UPLC, GC) using UV, DAD or FID detectors

Get an overview of the platform’s facilities via a virtual tour.


  • Identification and quantification of metabolites and compounds of pharmacological interest from complex matrices: biological fluids, tissues, cells, plants, etc.
    • Quantification of lipid mediators (bile acids, endocannabinoids, oxysterols, phospholipids, short chain fatty acids, etc.)
    • Structural identification of endogenous and xenobiotic derived metabolites
    • Identification and quantification of secondary metabolites of natural origin
  • Development and validation of LC-MS methods

Services available to

  • UCLouvain students and researchers
  • External collaborations