Main applications
Atomic force microscopy has recently opened a variety of novel possibilities for imaging and manipulating cell surfaces in their native environment, thereby complementing optical imaging techniques.
While AFM imaging offers a means to visualize cell surface structure at nanometer resolution and in physiological conditions, AFM force spectroscopy allows researchers to localize single cell surface receptors and to quantitatively probe cellular interactions.
- Nanoscale surface imaging of live cells and biosurfaces
- Detection, localization and conformational analysis of single molecules
Equipment
- BioScope Catalyst (Bruker)/Observer Z1 (Zeiss)
- BioScope Resolve (Bruker)/Observer Z1 (Zeiss)
- NanoWizard III (JPK)/Observer Z1 (Zeiss)
